The following modules were posted in 2025:

• Week of January 6: Pilot and feasibility studies for pragmatic trials (Implementation & Impact)

• Week of January 13: Trial designs and randomization schemes: Part 2 (Trial Design)

• Week of January 20: Trial designs and randomization schemes: Part 3 (Trial Design)

• Week of January 27: RegisterNow-1 (Exemplar Trial)

• Week of February 3: Endpoints and outcomes in pragmatic trials (Trial Design)

• Week of February 10: Ethical and regulatory complexities in pragmatic trials (Ethics, Consent, & Regulations)

• Week of February 17: Considerations related to consent in pragmatic trials (Ethics, Consent, & Regulations)

• Week of February 24: AcT (Exemplar Trial)

• Week of March 3: No module (Conference Break)

• Week of March 10: Intervention fidelity and adaptations during the trial (Implementation & Impact)

• Week of March 17: Use of routinely collected data in randomized trials: Part 2 (Data)

• Week of March 24: Contrast RISK (Exemplar Trial)

• Week of March 31: Trial designs and randomization schemes: Part 4 (Trial Design)

• Week of April 7: Estimands in clinical trials (Statistics)

• Week of April 14: Statistical analysis plans for clinical trials (Statistics)

• Week of April 21: STRATUS (Exemplar Trial)

• Week of April 28: Data and safety monitoring in pragmatic trials (Quality Control & Oversight)

• Week of May 5: Patient-reported outcomes in pragmatic trials (Data)

• Week of May 12: Statistical analysis in trials: an introduction (Statistics)

• Week of May 19: Be-Free (Exemplar Trial)

• Week of May 26: Sample size and power calculations: an introduction (Trial Design)

• Week of June 2: P-values, confidence intervals, and multiple testing (Statistics)

• Week of June 9: Biases in clinical trials: an introduction (Trial Design)

• Week of June 16: Covariate adjustment in randomized trials (Statistics)

• Week of June 23: Missing data in clinical trials: an introduction (Data)

Year 2 Modules

• Week of July 7: Explanatory vs. Pragmatic Trials (Intent & Question)

• Week of July 14: Crafting Pragmatic Trial Questions (Intent & Question)

• Week of July 28: Design Foundations for Pragmatic Clinical Trials (Trial Design)

• Week of August 5: Choosing Outcomes and Endpoints (Trial Design)

• Week of August 11: Choosing Outcomes and Endpoints - The Equity Lens (Trial Design & IDEA)