Module 1-3 – Feasibility & Partner Input in Question Development (8-min video).

• Summary: This module guides learners through transforming initial concepts into practical, partner-supported research questions for pragmatic trials. The module emphasizes early stakeholder involvement—patients, clinicians, and system leaders—to sharpen questions and boost feasibility. Participants will learn a structured approach to assess trial viability, address workload concerns proactively, and use coordinator-led reconnaissance methods, including rapid surveys and workflow observations. We use the MyTEMP dialysis trial to illustrate how early partner input uncovered hidden barriers and improved research design. By aligning trial goals with partners' priorities, researchers can secure stronger buy-in and prevent implementation pitfalls. 

** The content, slides, and narrator's voice were generated with the assistance of artificial intelligence, with human guidance and oversight throughout the process.

Dr. Deborah Marshall on NCTP: Driving Evidence-Informed Health System Change (5-min video).

• Summary: Dr. Marshall, Academic Supervisor of the National Cohort Training Program (NCTP), shares how the program supports embedded research and drives real-world impact in health system transformation. Learn how NCTP is training the next generation of researchers to contribute meaningfully to evidence-informed decision-making. 

NIH Pragmatic Trials Collaboratory (Living Textbook): Section 3 - Deciding Who to Engage: 1-page website. 

• Pragmatic clinical trials rely heavily on engaging the right partners (e.g., patients, caregivers, healthcare professionals, system leaders, insurers, regulators, funders, researchers, and manufacturers). These partners can help develop the research question, trial design, overcome challenges, and ensure the findings matter to those who will use or be impacted by the trial. Through inclusive collaboration, pragmatic trials produce valuable evidence that benefits patients and healthcare providers, making research more relevant and effective in real-world settings.