Identifying the intention of the trial and mapping this to a clearly articulated research question is crucial. This section overviews the differing objectives of explanatory vs. pragmatic trials: e.g., explanatory trials often involved highly controlled trial implementation/management to maximize adherence to the intervention, whereas pragmatic trials allow for deviations in how interventions would be delivered in the real-world.
Modules from this section, featured in previous weeks, will be posted here over time.
Week of July 8, 2024: Explanatory (“traditional”) vs. pragmatic clinical trials
Week of July 29, 2024: The PRagmatic Explanatory Continuum Indicator Summary (PRECIS-2) Tool
Week of September 2, 2024: Determining your intent and question through partnerships
Week of December 2, 2024: Reinforcing the fundamentals: Understanding your intention and refining your research question