2026 REGION IV FAIR: Saturday, March 14, 2026 from 8am - 2pm
LOCATION: Joyce Cummings Center, Tufts University
We are excited to move to a larger space at Tufts University this upcoming fair. Click here to learn how to enter. Please click here for deadlines and a tentative schedule for the day.
Congratulations to all our 2025 award winners! Click here to see all 2025 prize winners and to see a list of students who advanced to MSEF.
Congratulations to Ethan Yan, our 2025 Sanofi Specialty Care Grand Prize Winner and ISEF Representative for Region IV!
Ethan Yan, Groton School, "Empowering Low-Resource Settings with RetinAI: An AI System with Wearable Headset and Retinal Imaging for Eye Tumor Home-Screening"
Congratulations to our 2025 First Place Winners! Listed in alphabetical order by first name.
"The Effects of Environmental Concentrations of Caffeine on the Neurobehavioral and Neurobiological development of Zebrafish Embryos"
"Inequality in the Age of AI: An Agent-Based, Machine Learning Approach to Explore AI and Economic Inequity"
"Artificial Intelligence-based Optical Treatment of Vitiligo"
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The six Regional Science Fairs serve as qualifying competitions for the Regeneron International Science & Engineering Fair (ISEF) and the Massachusetts Science & Engineering Fair (MSEF). At the Region IV Competition, the top project is nominated for ISEF, and the top 40 projects advance to MSEF where the awards total over $500,000.
To learn how to enter the Region IV Fair, visit our HOW TO ENTER section.
Learn more about the Massachusetts Science & Engineering Fair
Learn more about the International Science & Engineering Fair