• Class: Antiemetic

• Action: blocks serotonin receptors centrally and peripherally at the vagal nerve terminal in the intestine

• Indications: vomiting

• Adverse Effects: agitation, anxiety, ataxia, dizziness, drowsiness, dystonia, fever, headache, hypotension, arrhythmias, chest pain, palpitations, prolonged QT interval, shock, tachycardia, torsades de pointes, bronchospasm, shortness of breath,

• Contraindications: Pregnant

• Special Considerations: Pregnancy category B

Dosages:

Adults:

Active nausea/vomiting

• IV 4mg

• IM 4mg

• PO 4mg

Pediatrics:

Active nausea/vomiting 0.1mg/kg IV/PO

COG's

COG's - Abdominal Pain/Vomiting (google.com)

COG's - Pediatric Abdominal Pain/Vomiting (google.com)