• Class: neuromuscular blockade NON-depolarizing, ***RSI drug***

• Action: Antagonizes acetylcholine at the motor end plate producing skeletal muscle paralysis.

• Indications: To induce neuromuscular blockage for the facilitation of advanced airway / ET tube placement.

• Adverse Effects: muscle paralysis, apnea, dyspnea, respiratory depression, sinus tachycardia urticaria.

• Contraindications: Known sensitivity to bromides. Use caution in heart and liver disease patients.

• Special Considerations: Pregnancy Class B

Dosages:

Adults:

• IV 0.6 - 1.2mg/kg

• IO 0.6 - 1.2mg/kg

Pediatrics:

(older that 3 months) 0.1mg/kg to MAX of 2mg

COG's

COG's - Rapid Sequence Intubation (google.com)