• Class: Electrolyte, mineral, anti-inflammatory

• Action: Required for normal physiologic functioning. Magnesium is a cofactor in neurochemical transmission and muscular excitability.

• Indications: Torsades de pointes, cardiac arrhythmias associated with hypomagnesaemia eclampsia and seizure prophylaxis in pre-eclampsia and status asthmaticus.

• Adverse Effects: Toxicity may cause muscle paralysis, weakness, hypothermia, cardiac, respiratory or CNS depression

• Contraindications: AV Blocks, GI obstruction, renal impairment

• Special Considerations: Pregnancy Class A

Dosages:

Adults:

Cardiac arrest (V-fib/V-tach/Torsades) 1-2g in 10ml D5W IV/IO over 5-10 mins

Torsades WITH a pulse: 1-2g in 100ml D5W IV/IO over 5-60 mins

Eclampsia 2-4g IV/IM

Status Asthmaticus 1.2-2g slow IV/IO over 20 mins.

Pediatrics:

20-50mg/kg to MAX dose of 2g for pulseless V-Tach/Torsades and status asthmaticus.