Shimadzu LCMS-8030 Triple Quad

The Shimadzu LCMS-8030 is a powerful Triple Quadrupole Liquid Chromatography-Mass Spectrometry (LC-MS/MS) system used for highly sensitive and accurate quantification and confirmation of trace-level analytes in various matrices. 

Types of Samples and Applications:

This system is particularly well-suited for the analysis of samples in complex matrices and is employed in various fields, including: 

• Biological Specimens: Detecting and quantifying drugs and metabolites in biological samples.

• Environmental Monitoring: Analyzing environmental contaminants and pesticides in various samples.

• Food and Beverage Analysis: Screening for pesticides and other contaminants in food and beverages.

• Pharmaceutical Testing: Identifying and quantifying genotoxic impurities, as well as performing Bioanalytical (BA) and Bioequivalence (BE) studies.

• Biotechnology, Clinical, Diagnostic, and Research Laboratories: Used for various applications requiring sensitive and quantitative analysis. 

Capabilities of the LCMS-8030 Triple Quad UV-VIS:

The LCMS-8030 boasts several features and capabilities that make it a powerful analytical tool: 

• Triple Quadrupole Mass Spectrometry (TQ-MS): This technique is ideal for sensitive quantification and confirmation of target analytes.

• Ultra-Fast MRM Transitions: Offers rapid analysis with dwell times as low as 1 msec and pause times of 1 msec, enabling high-speed multi-analyte detection (up to 555 channels per second).

• Ultra-Fast Polarity Switching: Achieves rapid polarity switching in just 15 msec, allowing for comprehensive analysis of both positive and negative ions.

• UFsweeper® Technology: A patented technology that accelerates ions out of the collision cell for efficient collision-induced dissociation (CID) and ultra-fast ion transport, minimizing sensitivity losses and crosstalk.

• High-Speed Scanning: Features a high scanning rate of up to 15,000 u/sec, allowing for full spectrum scans within a series of MRM measurements.

• Robust and High-Sensitivity Detection: The heated ion source handles challenging samples and offers high-sensitivity detection using ESI, APCI, or a dual-probe ionization interface.

• Easy Maintenance: Streamlined maintenance procedures, including quick and straightforward cleaning of the heated desolvation capillary, ensure greater system uptime and usability.

• Seamless Integration with UHPLC Systems: When coupled with Shimadzu's Nexera UHPLC, the LCMS-8030 provides a unified platform for enhanced qualitative and quantitative analysis, increased productivity, and accelerated workflows. 

Note: The UV-VIS detection component enhances the system's capabilities by providing orthogonal detection for compounds with UV-Vis absorbance. Triple quadrupole mass spectrometry primarily provides information based on the mass-to-charge ratio and fragmentation patterns of ions, while UV-Vis detection is based on the absorption of light at specific wavelengths.