Located in room SNR 1224.
Below the specifications is the calendar to schedule appointments, and below that is the calendar showing all scheduled reservations:
You must be logged into a @georgiasouthern.edu or Gmail account to reserve instrument time.
The Bruker Microflex MALDI-TOF is a versatile mass spectrometry instrument that can be used to analyze a variety of samples, especially in the fields of microbiology and life sciences.
Samples you can analyze with the Bruker Microflex MALDI-TOF:
Microorganisms: The MALDI Biotyper® system, based on Bruker's MALDI-TOF technology, is widely used for identifying bacteria, yeast, molds, and mycobacteria. This includes clinical isolates from various sources like blood, urine, tissue, and wounds. The system uses the unique proteomic fingerprint of an organism to identify it by matching it with a comprehensive reference library.
Peptides and Proteins: It's useful for protein or peptide characterization, including determining primary protein sequences and detecting post-translational modifications like disulfide bonds.
Polymers: The instrument can be used to determine absolute molecular weight distributions of synthetic polymers, even those with high molecular weights up to 500 kDa.
Oligonucleotides and Small Molecules: The technology allows for the analysis of oligonucleotides and small molecules.
Other Biological Samples: MALDI-TOF MS can also be applied to the analysis of complex samples like blood cultures (after sample preparation), urine, and cerebrospinal fluid.
Food and Beverage Samples: It's used for purposes such as classifying oils to detect adulterations, determining components in milk products, and analyzing wine.
Capabilities of the Bruker Microflex MALDI-TOF:
Rapid and Accurate Identification: It significantly reduces the time required for identification compared to traditional methods, providing accurate results in minutes for many applications.
High-Throughput Analysis: The technology allows for the rapid analysis of a large number of samples.
Ease of Use: The system is designed with intuitive operations, making it suitable for both experienced and non-expert users.
Broad Application Range: It can address a wide variety of analytical challenges in fields like clinical microbiology, food quality control, and polymer analysis.
Flexibility in Ionization Mode: The instrument can be used in either positive or negative ionization modes, allowing for the analysis of different types of analytes.
Robust and Reliable Performance: Features like an integrated oil-free vacuum system and stable ion generation contribute to its reliability.
Data Analysis Software: Dedicated software packages support data visualization, target characterization, and the creation of custom libraries for specific research needs.
Cost-Effectiveness (Long-Term): While the initial instrument cost may be high, the reduced cost per sample compared to many other identification methods can lead to cost savings over time.
In summary, the Bruker Microflex MALDI-TOF is a powerful and versatile tool for research and routine analysis in various fields, with a strong emphasis on rapid and accurate identification of microorganisms and characterization of biomolecules and polymers.