Rigaku Synergy-i XRD

The Rigaku XtaLAB Synergy-i XRD with Cryo-cooling is a single-crystal X-ray diffractometer that uses a hybrid photon counting (HPC) detector. It offers enhanced capabilities through its cryo-cooling system. 

Samples for use:

The XtaLAB Synergy-i with cryo-cooling is mainly for single-crystal X-ray diffraction (SC-XRD) analysis. This technique determines the atomic structure of crystalline samples. With cryo-cooling, it is useful for studying: 

• Sensitive organic materials and proteins: Cryo-cooling helps minimize radiation damage to delicate organic crystals and proteins, preserving sample integrity.

• Weakly diffracting materials: Lower temperatures can minimize thermal vibrations, resulting in sharper diffraction patterns and better signal-to-noise ratios, making it easier to study materials that diffract weakly.

• Materials prone to radiation damage: The XtaLAB Synergy-i can use Mo and/or Cu sources, allowing a broad range of sample types to be studied. Mo Kα radiation is ideal for evaluating large crystal samples, crystals containing heavy atoms, and densely packed inorganic materials, which can be prone to absorption effects. 

Capabilities:

The Rigaku XtaLAB Synergy-i XRD with Cryo-cooling has several key capabilities:

• High-quality data collection: Equipped with a HyPix-Bantam HPC detector, the system allows for direct X-ray photon detection and counting, leading to low-noise images and enhanced data quality.

• Minimized radiation damage: The integrated cryo-cooling system (such as the Oxford Cryostream 1000 or Oxford Cobra) suppresses radiation damage, particularly beneficial for sensitive samples like proteins and organic materials.

• Precise structure determination: By minimizing thermal vibrations and radiation damage, the system facilitates more accurate atomic position determination, bond length and angle measurements, and crystal lattice symmetry analysis.

• Enhanced signal-to-noise ratio: Cryo-cooling leads to sharper diffraction patterns and an improved signal-to-noise ratio, enabling the study of materials that diffract weakly.

• Flexible X-ray sources: The instrument can be configured with Mo and/or Cu sources allowing for tailored analysis depending on the sample type and characteristics.

• High-precision goniometer: A 4-circle kappa goniometer enables precise sample orientation and data collection.

• User-friendly software: The system is controlled by the intuitive CrysAlisPro software, simplifying data collection and processing.

• Automated structure solution: CrysAlisPro includes automated tools for crystal screening, data reduction, and structure solution. 

In short, the Rigaku XtaLAB Synergy-i XRD with Cryo-cooling is a powerful tool for single-crystal X-ray diffraction, offering superior data quality and the ability to investigate sensitive and challenging crystalline materials by mitigating the effects of radiation damage and thermal vibrations.