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Technologies for proteomic sample processing, automation and tissue homogenization/cell lysis
I. Automation
Automated high throughput LC-MS sample preparation workflow
PreON (PreOmics) instrument for full automation
iST is used on established platforms from Agilent, Hamilton and Tecan
PreOn Platform
True walk-away automation for label-free and chemical labeling workflows
Eliminates manual processing steps (only 5 min hands-on time)
Works seamlessly with pre-loaded PreOmics protocols
Generates standardized and highly reproducible results
11 and 16 plex TMT (including ACN & hydroxylamine)
II. Protein Extraction
BeatBox hardware for quick, effective and flexible tissue homogenization and cell lysis
Fast: 1-96 samples processed in parallel in less than 10 mins
Easy-to-use: Add your sample into preassembled kits and run with just two clicks
Efficient: Enhance the protein identification rate using the BeatBox in combination with the iST kits
Flexible: Homogenize everything from cells to tough muscle tissue; either in 96well or 24 single tube format
Revolutionary: Small footprint, silent, and minimal heat induction in sample
Application for BeatBox
BeatBox homogenates show the highest protein yields
Reproducibility of protein yields from different tissues were increased 2.5x using BeatBox
Increase in protein identifications by, on average, 40% compared to unfractionated samples
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