16)

“Synthesis of pironetin and related analogs: studies on structure-activity relationships as tubulin assembly inhibitors.” Watanabe H, Watanabe H, Usui T, Kondoh M, Osada H, and Kitahara T. J. Antibiot., 53, 540-545 (2000).

15)

“Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues.” Wang H, Usui T, Osada H, and Ganesan A. J. Med. Chem., 43, 1577-1585 (2000).

14)

“Synthesis and evaluation of microtubule assembly inhibition and cytotoxicity of prenylated derivatives of cyclo-L-Trp-L-Pro.” Sanz-Cervera JF., Stocking EM, Usui T, Osada H, and Williams RM.Bioorg. Med. Chem., 8, 2407-2415 (2000).

13)

“Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes.” Ganesh S, Agarwala KL, Ueda K, Akagi T, Shoda K, Usui T, Hashikawa T, Osada H, Delgado-Escueta AV, and Yamakawa K. Hum. Mol. Genet., 9, 2251-2261 (2000).

12)

“Protein phosphatase 2A inhibitors, phoslactomycins. Effects on the cytoskeleton in NIH/3T3 cells.” Usui T, Marriott G, Inagaki M, Swarup G, and Osada H. J. Biochem., 125, 960-965 (1999).

11)

“Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin.” Kondoh M, Usui T, Nishikiori T, Mayumi T, and Osada H. Biochem. J., 340, 411-416 (1999).

10)

“Tryprostatin A, a specific and novel inhibitor of microtubule assembly.” Usui T, Kondoh M, Cui CB, Mayumi T, and Osada H.Biochem. J., 333, 543-548 (1998).

9)

“Syntheses and bioactivities of acetophthalidin and its derivatives.” Uchida K, Watanabe H, Usui T, Osada H, and Kitahara T.Heterocycles 48, 2049-2060 (1998).

8)

“Cell cycle arrest and antitumor activity of pironetin and its derivatives.” Kondoh M, Usui T, Kobayashi S, Tsuchiya K, Nishikawa K, Nishikiori T, Mayumi T, and Osada H. Cancer Lett., 126, 29-32 (1998).

7)

“Effects of tryprostatin derivatives on microtubule assembly in vitro and in situ.” Kondoh M, Usui T, Mayumi T, and Osada H. J. Antibiot., 51, 801-804 (1998).

6)

“Biochemical differences between staurosporine- induced apoptosis and premature mitosis.” Yoshida M, Usui T, Tsujimura K, Inagaki M, Beppu T, and Horinouchi S. Exp. Cell Res., 232, 225-239 (1997).

5)

“A novel HSP70 gene of Schizosaccharomyces pombe that confers K-252a resistance.” Usui T, Yoshida M, Kasahara K, Honda A, Beppu T, and Horinouchi S. Gene 189, 43-47 (1997).

4)

“A K-252a-resistance gene, sks1+, encodes a protein similar to the Caenorhabditis elegans F37 A4.5 gene product and confers multidrug resistance in Schizosaccharomyces pombe.” Usui T, Yoshida M, Honda A, Beppu T, and Horinouchi S. Gene 161, 93-96 (1995).

3)

“Phosphatidylinositol-3 kinase in fission yeast: a possible role in stress responses.” Kimura K, Miyake S, Makuuchi M, Morita R, Usui T, Yoshida M, Horinouchi S, and Fukui Y. Biosci. Biotechnol. Biochem., 59, 678-682 (1995).

2)

“Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a.” Usui T, Yoshida M, Abe K, Osada H, Isono K, and Beppu T. J. Cell Biol., 115, 1275-1282 (1991).

1)

“Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases.” Abe K, Yoshida M, Usui T, Horinouchi S, and Beppu T. Exp. Cell Res., 192, 122-127 (1991).