Key Players in the Cell Expansion Market: A Product-Centric Analysis

The global cell expansion market was valued at USD 17.75 billion in 2022 and is anticipated to grow at a CAGR of 12.85% from 2023 to 2030. A significant driver of this market is the increasing use of automated solutions in cell expansion applications. These automated systems help reduce both labor costs and expenses associated with producing Cell Therapy Products (CTP), gene therapies, and other biologics, resulting in more robust and reliable production processes.

Key industry players involved in CTP development are actively expanding their product offerings to meet the surging global demand for these therapies. For example, in January 2021, Thermo Fisher Scientific launched the Gibco CTS OpTmizer Pro Serum Free Media platform, designed for developing and expanding human T lymphocytes for cell therapy developers working with allogeneic workflows. This innovative platform focuses on optimizing donor cell metabolism, making it particularly well-suited for allogeneic, off-the-shelf cell therapies.

Additionally, the industry is witnessing a significant shift towards Single-Use Systems (SUS), which offer notable production advantages in CTP manufacturing. SUS effectively eliminates the risks of cross-contamination and culture contamination that may arise from inadequate sterilization. Moreover, SUS facilitates the production of CTP with high cell densities and provides long-term cost savings. As the adoption of SUS increases, the development of CTP accelerates, further driving market growth.

The popularity of cellular therapies within the life sciences sector is on the rise, supported by a notable increase in funding from both private and government organizations. Initiatives aimed at promoting the development of cellular therapies are also contributing to market growth. The International Society for Stem Cell Research is actively involved in identifying funding opportunities related to stem cell research across various biomedical applications.

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Product Insights

In terms of product segmentation, consumables led the market in 2022, accounting for 45.7% of the overall market share. This segment is projected to maintain its leading position throughout the forecast period. The availability of a diverse array of commercial media and reagent products tailored to specific cell types significantly contributes to the revenue share of this segment. Additionally, these consumable products are convenient, ready-to-use, and available in serum-free formulations.

For instance, in May 2023, Lonza introduced the TheraPEAK T-VIVO Cell Culture Medium, a chemically defined medium optimized for the production of CAR T-cells. This non-animal-origin medium enhances consistency and process control, facilitating regulatory approval and expediting cell therapy development.

The instruments segment is projected to experience the fastest growth, with a CAGR of 13.18% during the forecast period, primarily due to the trend of automation in bioreactors and other expansion platforms aimed at improving the efficiency of culturing procedures. The introduction of automated platforms standardizes the cell expansion process and enables effective process tracking while reducing the need for hands-on intervention, thus optimizing the utilization of skilled personnel's time.

In September 2022, Terumo Blood and Cell Technologies (Terumo BCT) launched the Quantum Flex Cell Expansion System, a bioreactor platform designed for the development and manufacturing of cell and gene therapies (CGT). This platform aims to automate various processes, eliminate time-consuming steps, and streamline technology transfers. The continuous introduction of automated culturing equipment is expected to significantly boost revenue generation within the instruments segment, as these innovations enhance production capabilities and efficiency in cell expansion processes.

Overall, the combination of automation trends, increasing demand for cellular therapies, and ongoing product innovation positions the global cell expansion market for substantial growth in the coming years. The industry’s focus on improving process efficiency and reducing costs will likely drive further advancements in both consumables and instruments, ensuring continued market expansion.

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