Vee Xu
Stem Cell Internship: Alexanian Lab, Gladstone Institutes
Poster: Unbiased Proteomics on CRISPR-Affinity-Purified Enhancers to Identify New Mechanisms of Fibrosis
Stem Cell Internship: Alexanian Lab, Gladstone Institutes
Poster: Unbiased Proteomics on CRISPR-Affinity-Purified Enhancers to Identify New Mechanisms of Fibrosis
Vee is an experienced professional in natural language processing, specializing in summarization and machine translation. Before transitioning to biotechnology, Vee worked as an international film project manager in the entertainment industry. Her current career goal is to advance in bioengineering, with a particular focus on bioinformatics.
Vee completed her Bioscience internships at UCSF, where she researched histidine kinase signal transduction and microfluidics. At UCSF's DeGrado Lab and Abate Lab, she explored the signal transduction mechanisms of histidine kinase using de novo proteins and demonstrated the advantages of culturing and sorting bacteria in microdroplets. She honed her wet lab skills in cell culture, library preparation, cell sorting, and microfluidic device fabrication and operation. Additionally, she developed bioinformatics skills in analyzing genetic mutations and protein structures, devising gating strategies for FACS, and simulating droplet sorting conditions.
During her Stem Cell Internship at the Gladstone Institutes, Vee focused on the mechanisms of cardiac fibrosis, using CRISPR-affinity purification of regulatory elements. She also screened transposable elements for broad-targeting epigenetic regulation of cardiac fibrosis. Her training continued in the 2023-2024 academic year, where she delved into proteomics and fibrosis mechanisms at Gladstone Institutes.
The most rewarding aspects of Vee's internships have been collaborating with talented scientists to derive logical and experimental proofs for scientific questions while receiving invaluable mentorship. She looks forward to sharing her journey and insights in bioengineering and bioinformatics.
Spring 2023
Bioscience Internship: DeGrado Lab, UCSF
Internship Mentor: Dr. Katie Hatstat
Poster: Thermodynamic Modeling of the Two-component Signaling System in Histine Kindase Using CpxA-5wlk Chimeras
Vee and Max with their mentor, Katie, discussing experimental equipment.
Vee talking with Katie.
Alexanian lab outing
Vee with her internship poster at the Spring 2023 Biosymposium
Vee and Dr Shinya Yamanaka
2023-2024 CCSF CIRM interns