It follows the story of Maki and Aira, two high school students who become embroiled in a series of bizarre and otherworldly encounters after they explore their interests in the supernatural and the occult. The narrative is filled with dynamic battles against various supernatural entities, as well as humor stemming from the characters' personalities and interactions. The artwork is vibrant and energetic, enhancing the intense action scenes. "Dandadan" is notable for its unique blend of horror, comedy, and adventure, appealing to fans of shonen manga and those looking for something fresh and unconventional.