For this unit, we learned about about DNA and the roles it plays during protein synthesis. In this project, we were assigned to research a specific disease that shows a mutation in the genetic code. We were to observe the effects that the disease has on one's structure and function.
For this project, we started off by doing a strawberry DNA extraction lab to practice analyzing actual DNA in a living organism. After learning about DNA and the role it plays in our lives, we studied the process of protein synthesis along with the stages. Transcription and translation are important concepts to know with this information. We, as a class, took a lot of time in order to understand these steps by translating the DNA into the mRNA sequence. Additionally, we learned about the mutations in DNA and applied this knowledge to the Protein to Disease project. My partner, Sadie, and I decided to research Parkinson's disease. As shown, we saw the mutations in the DNA and RNA sequence and how this disease affects the structure of humans.
Parkinson's is a disease in the central nervous system of the body that affects one's physical movement. This is the disease that we researched about for our Protein to Disease project.
Transcription is the process of copying a segment of DNA into RNA. This is the first stage of protein synthesis.
Translation, the second stage of protein synthesis, is the process in which ribosomes in the cytoplasm or endoplasmic reticulum synthesize proteins.
DNA is the genetic molecule that carries the genetic code and allows for development, functioning, growth, and reproduction.
RNA is a polymeric molecule that helps in the process of protein synthesis.
This is the sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid during protein synthesis.
This is a trinucleotide sequence on a tRNA molecule that bonds to a complementary sequence on an mRNA molecule.
Ribosomes are complex molecules that perform biological protein synthesis. This is where translation takes place.
Amino acids are molecules that make up proteins. They regulate the translation of mRNA.
This is the process by which protein is translated to its 3-dimensional structure in order to properly function. It occurs in four stages: primary, secondary, tertiary, and quaternary.
This is the process in which cells produce more proteins throughout two stages: transcription and translation.
A disease is the disorder of a structure or functions of an organism caused by genes and/or external factors. The disease that we studied was Parkinson's Disease, which harms the central nervous system in the body.
A mutation is an alteration in the DNA sequence that causes a change in one's genetics. We the different mutations, which are substitution, deletion, and insertion.
Throughout the course of this unit, I think I worked efficiently with my partner. I found the Protein to Disease project very interesting and I enjoyed researching different diseases along with their genetic components.
Some areas that I succeeded in was communication and cultural competence. I feel that I communicated information clearly with my partner. Additionally, I communicated with my teacher when I didn't understand something by asking questions. As for cultural competence, I kept an open mind about the diseases that we were learning about by knowing that it can be a sensitive topic. I also was civically engaged in the project. For example, when other groups were presenting their projects, I made sure to be attentive and involved.
However, I could have worked on my critical thinking and my skills as a conscientious learner. I think I could have looked deeper into translation and transcription in terms of Parkinson's. I also could have managed my time better because I found myself feeling rushed to finish the project near the end. I will make sure to work on improving these skills for my future projects.