Publications
Publications in Chinese Journals
11. H. Dan, Y. Chen, X. Wei, Z. Zhu, L. Tang, Y. Li, X. Zhuang. 2002. Screening Microbial Herbicides from Weed DRB. Microbiology (Chinese), 29 (4): 5 – 9.
10. F. Wang, Z. Zhu, H. Dan, C. Wang, Y. Chen, X. Wei & L. Tang. 1999 . A fast toxicity detection method of Bacillus thuringiensis preparations. Journal of Southwest Agricultural University. 21 (1), 110 – 112.
9. C. Wang, H. Dan, Z. Zhu, X. Wei, Y. Chen, H. Lan. 1999. Resistance feature of Plutella Xylostella against Bacillus thuringiensis HD-1 preparations. Chinese Journal of Biological Control. 15 (1), 12 – 15.
8. Y. Chen & H. Dan .1998. Current situation on the research and application of microbial herbicides in foreign countries. Tianjin Agricultural Sciences. 4 (2), 5 – 9.
7. C. Wang, H. Dan, Y. Chen , B. Zhang, X. Wei & Z. Zhu.1997. Toxicity determination of Bacillus thuringiensis preparations using Plutella Xylostella - Brassica Campestris ssp. Chinensis var. communis leef method. Acta Agricultural Boreali-sinica. 12 (suppliment), 81 – 84.
6. H. Dan & Y. Chen. 1997. Tthe haemolytic properties of Bacillus thuringiensis subsp. Israelensis (B.t.i) and their applications in toxicity determination of B.t.i preparations. Microbiology (Chinese). 24 (6), 326 – 330.
5. Z. Zhu, C. Wang, G. Guo, Y. Chen ,H. Dan, H. Qu & J. Liu. 1997. The effects of spores of Bacillus thuringiensis HD-1 and TJ-20 on the susceptivities of Diamondback Moth. Acta Agricultural Boreali-sinica. 12(suppliment). 85 – 90.
4. H. Dan, X. Wei, Y. Chen & B. Zhang. 1996. Prelimilary report of the biological study on Bacillus thuringiensis fermentation. Tianjin Agricultural Sciences. 2 (1), 28 – 31.
3. C. Wang, Z. Zhu, X. Wei, Y. Chen , B. Zhang & H. Dan. 1996. Research of the effect of Bacillus thuringiensis (B.t ) synergist I on B.t preparations. Tianjin Agricultural Sciences. 2 (1), 26 – 27.
2. B. Zhang, C. Wang, X. Wei, H. Dan, Z. Zhu & Y. Chen . 1996. Preliminary report of the biological control of cotton bollworm (Heliothis armi) in field. Tianjin Agricultural Sciences. 2 (1), 21 – 23.
1. Y. Chen, C. Wang, B. Zhang, X. Wei & Z. Zhu. 1996. Research on the effect of Bacillus thuringiensis synergist II. Tianjin Agricultural Sciences. 2 (1), 24 – 25.
Conference abstracts
2. H. Dan, Y. Chen , X. Wei, Z. Zhu, L. Tang, Y. Li & X. Zhuang. 2001. Research of the screening of target strains for microbial herbicides from deleterious rhizobacteria on weeds. Proceedings of the Fourth Annual Academic Conference of Youth by China Association of Science and Technology . PP. 71.
1. H. Dan, C. Wang, Z. Zhu. X. Wei, Y. Chen & B. Zhang. 2001. Production and field application of the cotton bollworm (Heliothis armi) nuclear polyhedrosis viruses. Proceedings of the Science and Technology Conference of Tianjin Youth in 2001. 541 – 543.
Autophagy and cell death
12. Chen Y, Wei H, Liu F, Guan J-L. Hyper-activation of mTORC1 promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling. J Biol Chem. 2014, 289:1164-1173. (2012 IF=4.651)
11. Liu F, Fang F, Yuan H, Yang D, Chen Y, Williams L, Goldstein SA, Krebsbach PH, Guan JL. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast condensation and terminal differentiation. J Bone Miner Res. 2013, 28 (11): 2414-2430. (2012 IF=6.128)
10. Li L*, Chen Y*, Gibson SB. Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation. Cell Signal. 2013 Jan;25(1):50-65. *These two authors contributed equally to this work) (2012 IF=4.304)
9. Klionsky et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012, 8(4): 445-544. (2012 IF=12.042)
8. Chen Y, Klionsky DJ. The regulation of autophagy: unanswered questions. J Cell Sci. 2011 Jan 15;124(Pt 2):161-70. (2012 IF=5.877)
7. Chen Y, Azad MB, Gibson SB. Methods for detecting autophagy and determining autophagy-induced cell death. Can. J Physiol Pharmacol. 2010, 88: 285-295.(2012 IF=1.556)
6. Chen Y, Azad MB, Gibson SB. Superoxide is the major reactive oxygen species regulating autophagy. Cell Death Differ 2009, 16, 1040–1052. (2012 IF=8.371)
5. Azad MB, Chen Y, Gibson SB.Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment.Antioxid Redox Signal. 2009 April, 11 (4): 777-790. (Review) ( 2012 IF=7.189)
4. Chen Y, Gibson SB. Is mitochondrial generation of reactive oxygen species a trigger for autophagy? Autophagy. 2008 Feb 16: 4(2):195-204. (Review) (2012 IF=12.042)
3. Azad MB, Chen Y, Hensen ES, Cizeau J, McMillan-Ward E, Israels SJ, Gibson SB. 2008. Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3 . Autophagy. 2008 Feb 16; 4(2): 246-248. (2012 IF=12.042)
2. Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. 2007. Mitochondrial electron transport chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci . 120: 4155-4166 . (2012 IF=5.877)
This article has been highlighted at: Cancer cells die of consumption. J Cell Sci. 120: 2303e (2007).
1. Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. 2007. Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ 2008, 15: 171-182 . (2012 IF=8.371)
See Autophagy Research Front Maps
Representative conference abstracts
4. Y. Chen, MB, Azad. Mitochondria-generated superoxide is the major reactive oxygen species regulating starvation-induced autophagy. Keystone Symposia-Targeted Cancer Therapies (X8). Whistler, British Columbia, Canada, March 27 - April 1, 2009.
3. Y. Chen and SB. Gibson. CancerCare Manitoba Research Day: Superoxide but not hydrogen peroxide is the major reactive oxygen species to induce autophagy in cancer cells. Winnipeg, Manitoba, Canada, April 11, 2008.
2. Y. Chen, E. McMillian-Ward, J. Kong, SJ. Israels, and SB. Gibson. 2007. Reactive oxygen species induce autophagic cell death in transformed and cancer cells. Apoptotic and Non-Apoptotic Cell Death Pathways (Z4). Keystone Symposia. Monterey, California, April 15 - 20, 2007.
1. MB. Azad, Y. Chen, E. Henson, E. McMillian-Ward, J. Cizeau, S. J. Israels, and SB. Gibson. 2007. Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. Autophagy in Health and Disease (Z3). Keystone Symposia. Monterey, California, April 15 - 20, 2007.