Homunculus: Valorian Homunculi are humanoid organisms synthesized by concentrated mana and are therefore highly susceptible to Astralite, the primary weapon of Magekillers. A wound inflicted with such a weapon leaves a grievous wound that renders the body in excruciating pain and constant nausea until it can be purged or treated via a magical means. On the subject of mana itself however, as the bodies are forged through magic via intricate design, channeling too much too often will result in the inevitable decay of the body.
The bodies themselves were never designed to host an aging mechanism, so one might speculate that they could continue on indefinitely without fail. Unfortunately as the bodies fail to age alongside the mind there will be unavoidable consequences, and a highly stressful or dangerous lifestyle will eventually begin to cause severe mental instability, peaking in the mind's desire for release from the artificial body, regardless of how artfully built. The possibility of a slow decline to insanity can occur as early as one hundred and fifty, but it is more likely to occur around five-hundred years, given the lifestyle of the Homunculus.
A lifestyle which revolves around magic and sorcery will cause the homunculus to reach this breaking point far earlier than one which chooses to live in a isolated, or peacful manner. As of current none of these creatures seem to live, however a frightful number of identical, partially-formed ones were discovered in a dilapidated mansion that was plundered...