A randomized, double-blind, placebo-controlled, multicenter, dose range finding study, to evaluate efficacy, safety and pharmacodynamics of XXXX in mild to moderate hypertensive patients.
Summary: The treatment period is of 12 months (dosing interval Q6M) and is composed
Summary: The treatment period is of 12 months (dosing interval Q6M) and is composed
of 2 parts: Part 1: 6 month treatment period comprising 4 active arms at different
of 2 parts: Part 1: 6 month treatment period comprising 4 active arms at different
doses (75, 150, 300 and 600 mg) and one placebo. Part 2: 6 month treatment period in which all patients on placebo and 75 mg dose will be re-randomized to one of the 3 active arms (150, 300
doses (75, 150, 300 and 600 mg) and one placebo. Part 2: 6 month treatment period in which all patients on placebo and 75 mg dose will be re-randomized to one of the 3 active arms (150, 300
and 600 mg) and those patients already receiving active treatment will continue to do so.
and 600 mg) and those patients already receiving active treatment will continue to do so.
Type of study (PIC, Recruiting): Recruiting
Type of study (PIC, Recruiting): Recruiting
Commercial Study - Site Identification form required to be completed, please find Site ID form uploaded to study documents link below.
Commercial Study - Site Identification form required to be completed, please find Site ID form uploaded to study documents link below.
Recruitment Duration: 01/11/2025 - 01/11/2026
Recruitment Duration: 01/11/2025 - 01/11/2026
Practice Activity: See part B and Schedule of Events
Practice Activity: See part B and Schedule of Events
Practice Eligibility Criteria: GP practices within East Midlands
Practice Eligibility Criteria: GP practices within East Midlands
Practice Target: 3 per site
Practice Target: 3 per site
Is this Study Applicable for RSI Scheme?
Is this Study Applicable for RSI Scheme?
Yes, applicable for RSI scheme
Research Costs:
Research Costs:
Commercial research studies follow a national tariff guideline. Click here for more information on the tariff or download the tariff by clicking here
Commercial research studies follow a national tariff guideline. Click here for more information on the tariff or download the tariff by clicking here