South Bank station opened in 1889, as Vulture Street at the same time as the line. In September 1930, the standard gauge opened west of the station. On 18 September 1982, the line was electrified through the station from Roma Street to Kingston. In 1995, the standard gauge to the west of the station was converted to a dual gauge for the Gold Coast line. On 27 April 2001, the station was renamed South Bank (Vulture Street), later being renamed South Bank after the nearby South Bank Parklands and a platform was added to the dual gauge line.
South Bank station has three platforms consisting of an island platform and a side platform. Platform 1 is for outbound services, platform 2 is for inbound services and platform 3 is for selected peak services.
South Bank station has four station entrances. Two are from Grey Street, one is from Tribune Street and one is from Southpoint.
South Bank does have disability access.
South Bank busway station is located adjacent to South Bank station which is served by many bus services.