Nov 27 2020 notes
Sat, Nov 28, 2020, 11:48 PM
to Be
Genetic algorithms can often make things 30 to 2 to 3 times better; To my perception the body is already filled with networked systems and perhaps it is possible to remove all or most epigenetics at something like yeast or zebrafish, then that would leave rapid opportunity for stochastisticaly reintroduced saved data as well as of course breed billions of new yeast to find out if this techquenique which is strongly supported at google scholar can create longevevity increases, If it works at yeast they can try it at zebrafish
There is a single gene difference between caucasian and non caucasians, wikipedia says, “In 1999, the nacre mutation was identified in the zebrafish ortholog of the mammalian MITF transcription factor.[73] Mutations in human MITF result in eye defects and loss of pigment, a type of Waardenburg Syndrome. In December 2005, a study of the golden strain identified the gene responsible for its unusual pigmentation as SLC24A5, a solute carrier that appeared to be required for melanin production, and confirmed its function with a Morpholino knockdown. The orthologous gene was then characterized in humans and a one base pair difference was found to strongly segregate fair-skinned Europeans and dark-skinned Africans.[74] Zebrafish”https://en.wikipedia.org/wiki/Zebrafish#Scientific_research Utilizing that single base pair difference and making the caucasian version part of the germline of all mammals, including all homo sapiens, humans, people and persons is beneficial germline genetic engineering.
There is a wonderful idea of better than well. What might this look like at neurodevelopment; I read about neural crest development at wikipeida, so what would better than well look look like there?
measuring things causes the possibility of optimal knowledge isolates (comical I’m reminded of the phrease why protein isolate) and highly forgiving traversed or iterated or the actual neural crest pathways math and chemistry, at completely well neural crest development biology mauses can guide minds to recognition of valued paths and bruit about optima, although I think true optima are possible.
It is very ignorant of of me, but I saw a thing where Bell’s inequality could be expressed with three polarizers, I am reminded of how water surfaces polarize light and a person could make a pleasant water feature (undulating or laminar) with mirors in the right places so that the Bell’s inequality polarization overlap environment is continuously updated and refreshed, perhaps with enough of these to look at, and a sufficient number of physics enthusiasts looking at them a person will think of something new to say about about Bell’s inequality
Its Novemember 2020, and some people are getting nasal swab tests
eugenol or lidocaine, nanosomal with piezoelectric element driven penetration of the anesthetic; alibaba .1c to 1c piezoelement and half cent battery make this affordable.
snort microspheres, they puff up in the nose, and diffuse an enjoyable flavor (sucralose) simultaneous with absorbing a sample of fluid. Then do single nostril nose blow to gather sample, if snortatant colorant has made saliva colored then expectorate in tube as a replacement for a nose swab.
does the: gentle q tip in the ear pleasant sensation have anything comparable to the least-pressure but sufficient to gather a nasal swab sample?, that is, is there a nasal swab experieinece of extreme gentleness and vary narrow pressure range that actually feels good to neutral? Completely unknown to me.
Craigslist activity partner: let’s hang out! I’m unconcenred about your covid-19 tatus but am happy to use one of the free testing options so you can verfiy I’m harmless.
Reading about automated and human in-the-loop helpdesk automation software, I read “Many calls to the IT help desk originate from users who just want to know what directory to save work in and which printer is the closest to them” There are software based solutions which might well be better, but the cheapest (11/2020) GPS chip on alibaba is 20 cents, so printers, such as office printers could simply have a 9 cent version of that chip producing True 3D location that people could seek out when choosing a printer.
What to call a file and where to store it: with the cloud, parallel storage, or the impression of that, of one identical file at 20-100 differently labelled directories makes it so the computer can store a new file in a location that would make most sense for a computer to store a new file in like “documents” for a Microsoft office document; As a sloppy, untutored, or heavily rewarded human I might save it to the desktop; with cloud computing, or even just version synchronization off-net and HDD, clicking “save” which then alerts people to the fact that their document has been saved three or more ways: to the desktop, at the documents file folder, and as a long-abstract-length titled file, reminiscent of a search engine search result, called a Bing it up at Microsoft environments. So you click save, or it autosaves these three versions, at least 1-3 of them will be be mentally easy to find and remember, or importantly, spot, with human recognition memory.
unicode shapes ⚮ ╗⌇⌋ ⌬⌝ ⎦ ⏖ ⏣
∿∿∿ Ⅎ ᴤ
Looks like game of life glider gun ⠫
placenta vessels based heart lung machine, notbably keep lab mammals and humans alive as long as possible, then map things that go amiss during first 400 years of sustained living
royal jelly does HDAC epignenetics, neutral version as well as inverse of royal jelly epigenenti change could be tested as to any effect on longevity, if there is none then royal jelly longevizes without an epigenentic componenent. If there is a longevization epigenetic component to royal jelly at mammals, like mouse study, then the Even Moreso variation with hyperacetylation/Hypoacetylation/hyper and hypomethylation varieties of the beneficial epigenetics tried
I was reading about treatments from calcified coronary arteries. My perception is that I read among many procedures, those that involve grafts sometimes have the grafts themeselves calcify, causing nonoptimal effects, It seems possible that a soak up the crummy stuff vascular loop could be installed and then if it soaks up 90% of the circulating recalcifiers at the cicrulatory system then perhaps the heart vasculature might only do 10% as much recalcification, contributing to wellness and durable effectiveness of procedure, very crudely, it is possible to imagine a meter long extra loop of circulatory pathway tube used to absorb some of the “calcify” instruction chemicals, perhaps the GI tract vasculature could host the extra meter of tissue culture vessel length, and, perhaps be minimally invasive to swap out periodically;
I have previously written about ways to reduce diminuation of efficacy of drugs, on their repeated dosing, possibly including analgesic or also anesthetic drugs.
The internet says things that suggest a cure for low back pain would be of major benefit, “In both 1990 and 2013, the leading causes of ill health worldwide were: Low back pain, depression, iron-deficiency anemia, neck pain and age-related hearing loss.”
I noticed once when my back hurt that if I went to sleep it was likely to feel much better and be cured the next day on waking up. So, could they isolate that “it (back pain) fixes itself while alseep” to some brain sleep stage or pattern (EEG, REM, etc) then make a harmless nonhabituating Instant nap technology that lasts 3-7 minutes to create a restorative mini-nap that gets rid of back pain. Some possibilitities that come to mind are
Nanosomal instant sleep ambien nasal spray+REM inducer, or perhaps Slow-wave sleep (delta sleep peptide) peptide + “3 minute knockout from asthma whiffer”. The idea is that you get instant sleep, of the particular kind that causes recovery from back pain if there were an entire nap.
It might be too weak an effect, but playing back EEGs causes the brain to synchronize around they played-back waveforms; an EEG head playback circlet plus an instant nap chemical could do that.
Another possibility might be TMS (transcranial magnetic stimulation) that does either instant nap/nod off plus an optimal to back recovery sleep mimetic peptide.
If there is a messenger RNA profile of narcolepsy then that could be made into an RNA drug that causes instant sleep, again with the purpose of an instant micronap solving lower back pain just like a real nap.
The TMS focalization that causes P-zombie effects thing I saw published. could be another thing to switch on for 20-40 seconds to see if a P-zombie nap cures lower back pain, particulalrly, as like the other technologies, when combined with an EEG drug, or perhaps better, a drug that causes the EEG-like waves of a normal well back/spine. sort of like an electrospinalogram.
Botox may be effective against small back pain, the internet says, “Botulinum toxin A has been tried as a treatment for chronic low back pain . Although this practice is experimental and not well tested, it has shown promise. For example, in one small study of 31 people with chronic low back pain, botulinum A injection was compared to saline injection into painful back muscles. Pain relief was reported by most people as lasting 3 to 4 months.” That brings up the possibility of an ultraffordable topical cofocalized laser activated version of botox for back pain. The person applies the drug delivery (nanosomal, DMSOish, many others) topical botox, which is then only activated with light at tissue depth from a light emitting patch. As a technology the person with back pain would just get the ointment and photoactivating LED patch as a product at the grocery store. The botox could be photoactivated with a wide variety of published technologies, and a porphyrin moiety attached to the botox protein is just one of many numerous possible technological approaches.
The internet says there is a working topically applied specific area muscle pain ointment, I do not know how this works, but that localization through ointment rub-in location suggests that a lower back or other back areas topically migratory and effective photoactivated botox could also be effective. This could be a very affordable solution to back pain. The actual picograms of botulism toxin per dose is very affordable, and the $1 store has a 4 LED elastic toy wearable product. On alibaba that is likely 5-9 cents for the light emitting elastic wearable, and 1 cent or less for the photoctivateable (porphyrin) botox
I thought it could be beneficial to think of treatments, cures, and preventatives for heart disease, includinging atherosclerosis and heart attacks.
Hearts with less regularity and more chaotic attractor aspect are published as being healthier. That is the high variability chaotic attractor heart is weller longer. It might be possible to create a pill that nudges a heart to prefer the strange attractor math region. A big pill with lots of little pills in it it, each of which contained stochastic 1-.05 Hz dosing of something that harmlessly effected cardiovascular things (vasodilators, vasoconctrictors, stimulants, stochastic hawthorne active ingredients) such that there was a beneath the threshold of personal awareness chaotic nudge once every 1-5 seconds, this could causes an unwell heart to switch to a chaotic attractor program many many times each day, then they could measure to see if this reduced illnesss.
Perhaps the micro moment CA (chaotic attractor ) pill with bodyside only of the blood brain barrier active ingredients causes similar effect, completely excluding the nudges to chaotic attractor mode from having brain (feelable) effects.
It is possible that as a solution to menstrual cramping, or cramping with an IUD contraceptive, that a transcervical implant or IUD could have botox as a diffusive ingredient, which could be measured to see that it gets rid of menstrual cramping.
Wikipedia says 60% of people are absent ever experiencing low back pain, monozygotic twin studies could find the genetic basis of complete immunity to lower back pain, it is beneficial to make complete immunity to back pain a part of the germline of homo sapiens, that is humans, that is people.
somewhat analogous to changing the location of a needleless epidural anesthetic procedure 1.5 cm to a new location everyday for a month would keep any one location from from wearing out while still providing blockage of backache
Wikipedia notes that most people rapidly recover from small back pain, this brings up the possibility of geneticially isolating the equivalent of small back pain in agricultural animals, then breeding/engineering groups that recover from the veterinary equivalent of small back pain in 5% the median amount of time. The most parsimonious genetics of rapid recovery can be traced to particular genes and mRNA, then mRNA drugs based on that can be generated then tested to see if they make recovery much more rapid at median responder verterinary animals to see if these could also be RNA drugs that relieve human back pain with high rapidity.
longevity technology research area, online it says, “a hibernating groundhog's heart beats just five times” [ a minute], they could raise groundhogs in an environment where they hibernate 90% of the time time and another 0-10% of the time, then they could see if the long hibernating groundhogs had markedly longer lifespans than the 0-10% hibernating groundhogs. If they do, then groundhog (rodent) similarity to mice could be used to engineer a 90% hibernating mouse from groundhog genes and then the mice characterized as to why they were living much longer hibernating 90% of the time. Messenger RNA profiles (of eiher groundhogs immediately or 90% hibernator longevized mice) could be used to make RNA drugs to test to see if they make non-hibernating mice live longer and the RNA drugs, if any, that cause mice to live longer are then tested on age batched groups of marmosets (primates) to find out if this is a n RNA longevity drug that benefits primates; if it does it can be tested on age batched groups of human volunteers to see if it causes greater human longevity absent any effects deleterious to humans.
If groundhogs that hibernate 90% of the time live notably longer than groundhogs that only hibernate 0-10% of the time then they could also do a connected circulatory system parabiosis procedure linking a 90% hibernating groundhog to a 0-10% hibernating groundhog. If the 0-10% groundhog lives noticeably longer then they can find new chemicals (proteins, peptides) at the shared circulation that cause greater longevity and possibly wellness. Although several longevity parabioisis chemicals are published, this could be a completely new type, and be made into a human longevity drug.
What does it mean to actual things when a math system is particularly attracted to a 4th spatial or chronolological dimension? distribution outliers are favored perhaps, or just possibly poission distributions spontaneoueously make themselves prominent (sort of become a most frequently found vertice), if delayed quantum choice eraser retrocausality is true, what would combining its math and physics with a 4D time attractor math, and actual physical embodiminent do? The internet says, “These chaotic states are bounded by paths that form attractors, where the specific path is determined by initial conditions, much like the oscillation of a pendulum. However, whereas the damped pendulum attractor is a single point (the lowest point), attractors of nonlinear dynamical systems do not converge to a single dimensional point, but to a different dimension in three-dimensional space – a fractal dimension. Attractors that have a fractal dimension are known as ‘strange attractors’, so basically what if you just upped the math to make 4D starnge attractors, after you then know what they might look like from the equations you can look for them in nauture or build them. Finding 4D starnge attractors in naure could find many new phenomena. at measured systems, these might look like data that has a strong, not otherwise obviously sourced avoidance of regression to the mean and normal distributions. This could look like a distribution with a much higher amount of outliers. If a 4D strange attractor is prior knowledge about a system then perhaps it becomes (bayesian)
This one is kind of unlikely but they could do longevity (and wellness) mammal parabiosis math studies, where all the actual measureds are used to come up with a stack of little math models that, among other things, describe the math of the benefitting connected partner. those specific little maths could be used to design new drugs with. Let’s say at parabiosis the cardiostrange attractor of the benefitting mammal becomes more fractally variable, previously published as cardiobeneficial; or perhaps the benifittor becomes more circadian responsive (even in the absence of melatonin)
detect angina before it is ever felt
EDTA solution as keep alive solution for postvehicular accident hearts, measure calcification at 30, 60, 90,120, 300, 365 days prior to transplant to see if chelation actually does anything beneficial to cardiac tissue; the internet
A variety of lab mammals are used to model human atherosclerosis (2020), it is possible a longevity treatment published as causing greater, for example, rodent longevity grants the rodent models sufficient extended lifespan to better model atherosclerosis. So, if centrophenoxine is causing rodents to live 30-50% longer then they have that much more lifespan to develop atherosclerosis, and then can be used to develop new antiatherosclerotic drugs. Deprenyl at 24% greater longevity may also be beneficial, as could genetically modifying rodents to make more GDF-11 protein (I think I read female mice that overexpress GDF-11 live 47% longer). The combination of a longevity drug with a wider new area of testing out antiatherosclerosis drugs and gene therapies could be a beneficial new research protocol.
A kind of sideways approach to a new antidepressant and possibly anti-atherosclerotic is, noticing that stress causes macrophage activity that causes plaque build up and rupture, do something with the immune system that reduces, but to within normal range, macrophage activity; I may have read that when antigens are placed in some kind of phospholipid packaging or moietyization, that the person actually becomes less allergic to something they were previously sensistized to. If they made a pie chart of all the the things a normal person, as a well as an atherosclerotic person, as well as a depressed person are immunoreactive to then compare these three, to make a subset list, that provides a briefer list of things to do a possible immunopassivation therapy about, to decrease atherosclerotic reactivity, and also reduce the atherosclerotic stress from mental nonoptimality (stressy personality; depression).
Using a genetic alorithm to develop immunopassivation molecules and moieties; Note 100-1000 endogenous immunoreactive chemicals, then do a a kind of combinatorial phospholipid where the potential passivating moiety is a single variant on 1000 versions, such as length, liposomal anti-innumunogen passivation.
The internet has numerous immunopassivation and antigen desensitization drugs and protocols online.
immunopassivation (phospholipid moiety) of toxoplasmosis gondii antibodies could have mental health benefits (reference: the connection between cats and mental illness), reducing nonoptimal mental effects of toxoplasmosis gondii.
Shift (night) work is associated with less optimal health and possibly even nonoptimal longevity effects. It is possible using monozygotic twin human volunteers that that one could simulate shift (night) work, and the the other could continue day based activities. Immunoreactivity profiles of the two styles could be made, and then if there are any differences in the specific things new antibodies are made to either day/night then they could test an immunization to either mop up the deleterious shift work chemicals at the circulatory system, or immunopassivate (phospholipid moiety) existing antigens. Noting these shift-work chemicals are deleterious, it could be that even among day active persons immunizing against them, noting they may already circulate as a baseline, provides additional health and wellness benefit possibly a better than well effect.
As a new drug delivery method I have not ever previously heard of an injectable (airjectable) fluid or gel at the sublingual area. Advantages are much hight non-metabolized absorption, and the 1-12 month durability of a gel depot. Peptide drugs could beneficit from this.
Iodine sufficiency one dose treatment could be bellybutton depot airjection anywhere. about 1/10,000th of a gram is dialy iodine sufficiency, so a one gram depot injection could supply 3 decades of iodine, or being more engineering friendly, a 1/2 medium depot injection covinging 67% of USRDI sufficiency could provide two decades of iodine sufficiency;
The possible structural variations on phospholipids is likely more than trillions, notably at the phospholipids that have already been researched some are actually good for people (phopshatidylderine), Using yeast and microfluidics to mass screen phospholipids to find those that are even more beneficial to people is I think possible; as previviously described GFP yeast can accumulate more GFP the longer they live, and flow cytometry can then find the most optimal (greatest longevity) yeast treatments at about 10 million yeast screened per minute. During 2012 1 million or more c elegans could be flow cytometry sorted per 24 hours.
endolith phospholipids, rapamycin phospholipids, totoise phospholipids
comparative robustness of pubertal sperm and eggs cytes compared with supercentnerarian sperm and eggs; the difference between the two could have some kind of preervative factors;
stagnant water that is not stagnant, there are things called micyrhizzial communities where biotic communities have durable beneficial effect. I was thinkinging that ponds could have the same thing, human slecected microorganism mixtures that make the wateter safer to drink if a mammal drinks it. optimally people would treat their water first before drinking, but a 1/100 of crummy stuff precluded could make water treatment require 1/100 the infrastructure, making it 100 times cheaper (sort of; piping pumps) to treat. a green algae genetically engineered to glom what would otherwise be an essential nutrient for a pathogenic bacteria, perhaps lactoferrin made at algae or duckweek could preferentially utilize iron, keeping other bacteria from growing. risk of eutrophication, and staged ponds, (optimized pond scum ecology makes pondwater 1/10-1/100 as risky as it would otherwise be
shaker flashlight ice cream churn, ph swing
cox 2 immunization might make everything less achey and fervid, thinking of both milk cows and all mammals, “Mastitis has cost American dairy industries an estimated $1.5 to 2 billion per year in treating dairy cows (wikipedia)” It is possible an immunization to cycloxegenase II and I enzymes could reduce mastitis, making the lives of dairy cowsmore enjoyable. At humans, with safety testing, lifetime immunization against cyclooxygenase I and II could reduce incidence of cancr as well as reduce any joint achey or feverish symptoms throughout the lifetime.
thought the lifespan.
crispy duckweed naPCA
some fungi are deliquescent, purification of those chemicals, dependent on positive flavor, could be made a part of duckweed, and possibly be more deliquescent than NaPCA. selective breeding for most deliquescent edible gene product (such as genes trasferred from fungi) makes a duckweed or duckweed like plant that doubles volume every 16-24 hours that spontanteously turns to liquid when harvested.
g, like IQ genetics BDNF has numerous SNP versions, creating a completely new BDNF SNP could be tested at rodents and marmosets for greater cognitive ability, then this SNP variant of the BDNF gene made into a reversible human gene therapy, then upon further improvement is made an intelligence enhancing part of the human germline at all homo sapiens, that is people.
It is pretty simple to think of, ut it might have a longevity effect: Besides pineal chemicals that effect circadian rhythyms there are other chemicals that effect circadian rhythms (irisin), these could be tested on mice to see if they have a longevization effect noting the 20% longevization from melatonin supplementation at rodents.
a variety of species may have different circadian rhythm adjustor chemicals, which may be with or without any circardian effect on mammals like humans, these circadian rhythm adjustor chemicals could be tested as longeveity drugs.
The first human clock mutation was identified in an extended Utah family by Chris Jones, and genetically
characterized by Ying-Hui Fu and Louis Ptacek. Affected individuals are extreme 'morning larks' with 4 hour advanced sleep and other rhythms. This form of Familial Advanced Sleep Phase is caused by a single amino acid change, S662➔G, in the human PER2 protein
are there fungi with unusual circadian rhythms? like different spans, they could try these novel .5-1000 hour circadian rhythm chemicals out on c elegans and yeast to find out if any of them lengevize.
circadian rhythm chemicals in 400 year lifespan tortoises that are not in mammals are another possible place for longevizing chemicals to be found at.
I read that banana plants are 60% anologous gnetically to the human genome, nad plants have circadian rhythms. Making the circadian and ultradian rhythm chemicals (like proteins, possibly others) that plants make then feeding them to C elegans could find longevization chemicals.
Also, I read two things, one is that the difference between a perennial plant and annual plant can be as few as three genes (the internet), and then there is the other different area of how a plant on a certain light schedule can be made to be perennial or annual, it is very simplistic, but feeding c elegans perennial proteins could have a longevity effect.
a better version of a circadian rhythm gene could have the opposite effect of shift work, possibly reducing cardiocascular events; the very daytime version could be tested at atherosclerotic mice to see if it reduces cardiovascular events, this could be a beneficial improved gene to place at the human germline as it confers better than well “very day shift” effects.
saffron vision
gratitude journal discussion with Bob,
genetic algorithm wells30%-300% better effectiveness based on helicopter rotor beams and wind-power rotors (300%)
perhaps people would be waterborne illness resistant if their stomachs prouced enzymes that denature, zap, or otherwise neutralize proteins and microorganisms. Sources of these illness resistance chemicals could alsoready be at high concentration in other species, then gene therapy used to make them to be produced at homo sapiens. Vultures, hyenas, raccoons, crows could also be species that sustain their health over decades even though they eat rotten food; the technology here is that they could test detrivore/omnivores to find out if they have have stomach or gi tract enzymes, such as proteolytic enzymes that kill bacteria, perhaps cyst forms, as well as denature (make harmlesss) bacterial toxins. The bacteria/virus/cyst terminating enzymes then become water purification addititives (10 mg/gallon), as well as can be made a beneficial part of the human germline.
Wikipedia describes how proteolytic enzymes have been bred and engineered from bacteria. These biologically produced proteolytic enzymbes could have a big new wellness side branch, a proteolytic protein and spore denaturing material where a droplet placed in a gallon of water sterilizes the water. The protein then denatures at human stomach pH to be harmless and sensationless to humans. So, as a n example, you could just get 1-20 gallons of pond water, a 1-20 drops, wait 7-20 minutes (analogous to cold water “laundry detergent” proteolytic enzymes duration of action) then drink the water. “laundry detergent” proteases are only about $16-20/kg at alibaba, suggesting a new custom version that produces potable water could be, at 10 mg/gallon , 2c a gram is just two one hundredths of one cent to purify a gallon of water. As described these would be new bred/engineered proteolytic enzymes with an empahsis on sterilizing water and making it potable. It is beneficial to develop a proteolytic as well as bacteriolytic virolytic and sporolytic protein based enzyme that is producible at the stomach or also human GI tract as a gene therapy. This would cause untreated water to approach much fuller potability when drunk by a human being and benefits people.
Noting Dave Pearce’ Hedonistic Imperative and Abolitionist Manifesto there is a strong basis for genetically engineering all organisms with neurons to make GI tract proteolytic enzymes that make water potable for every species with neurons, as these all benefit from increased wellness.
biologically based sources of laundry detergent enzymes as water sterilants, either, amazingly, at the human GI tract, or as a golden rice/golden wheat/golden corn ingredient.
quats with thiosulfate, .0005% of a quat sterilizes water, then thiosulfate or some other (ph buffer)thing denatures quat, very high efficiency water sterilization; there could be a particular molecule quat where stomach acid defunctionalizes the quat, making drinking quat-sterilized water harmless
Bow head whales live more than 200 years. thinking about the possibility that bowhead whales might have different atherosclerosis, of some form that permits diving blood pressure effects, repeatedly, that could be thought of as figuring out puff and compress at bowhead whale vasculature, does it preclude cardiovascular plaque break-off and CHD, if so, what about bowhead whale CHD makes for the wider latitude greater survivavability vasculature. This could possibly be made into a gene therapy for humans to have, possibly along with just less or no atherosclerosis, but if if atherosclerosis were to occur it would be the bowhead whale kind.
Tortoises (400 year lifespan) and bowhead whales (over 200 year lifespan) might get pneumonia, at up to 400+ years, how do these organisms
CPP to lungs from circulatory system brings anti-pneumonia drugs, and possibly mucolytics preferentially to lung tissue,
I think I read that some nonhuman organisms that maintain the same mate decline if their partner organism ceases living, trace this to any of 100 different neurotransmitters and possibly even EEG effects, then come up with a better than well and partnered neutrotransmitter booster drug to test as a longevity technology to see if it causes greater longevity
There is some kind of thing where mountain and prairie voles partner up or do not partner up, but can interbreed, measure to see if they have differences in survival after partner nonaliveness; if they do, then figure out the difference in the longer lived variety to find out the mechanisms of precluding partner mediated deleterious lifespan effects, and find the biochemistry of better than partnered longevity effects.
LKM512 yogurt is published at about 2 studies as causing 80-90% lifespan increase in mice; give LKM512 yogurt to atherosclerotic mice to see if it causes greater longevity even with a non-cancer atherosclerotic mouse model
there is a DNA methylation thing called an epigenetic clock, I think may others must have alreaddy considered editing this clock as a way to increase lifespan. could the corpse of a superenteneratian, 99.999999% of the cytes as which, or more are still fully functional, extend or refute the methylation clock? Or find the places on it it, the actual tissues, that matter (neurons, vasculature)
its not cancer, its point of specificity tissue disregulation (hints of epigenetic clock going amiss at .000000000001% of tissue causing say atherosclerosis
genetically engineered-in anti-ischemia harm peptides as testable longevity drugs at atherosclerotic mice
mouse dorm n=40k, what causes a bruise to be scavenged successfully away, rather than treated as a body interior multicm dead tissue that could float out and cause strokes effect?
do the genetics of least bruising have any relation to cardiovascular wellness genetics? IS there any relation to longevity effects? Least bruising of human MZ twins correlates with what wellness benefit?
volunteer process, ultrasonic zapper bruises 1 cm tissue at 100k human volunteers with parents ages 70 on up. Correlate parental survival and lifespan with child non bruisability, advantage, basically harmless to the 40-50 year olds at experiment.
Pills that stop bruising may be longevizing, there may be a reduction of “microetherosclerotic” effects benefit as well.
“In one study, patients suffering from pigmented purpura — those deep purple bruises that get progressively worse — that took 50 mg of rutin (oral rutoside) two times per day along with 500 mg of Vitamin C twice a day were completely healed of their bruising within just four weeks.”, “hesperidin can dramatically reduce bruising and strengthen your capillaries”
60 second reactive stent, 20 seconds better
f=MA microsurgery, 2mm golfball core elastics can do 1.8 mm suturing at 90% mechanical engineering efficiency.
just explore the HOX and other state space to find completely well nonhuman primates with 2-3x the volume, span, and reach, of coronary arteries as regular primates, verify they are almost immune to lethal cardiovascular events from network and path duplication at the corononary vasculature.
should they just put in two hearts?
right handed heart people
apoe e immunue to ath at germline
Ok, so the source of tissue culture can be exceptionally well tissue, it is even possible that exceptionally well tissue with its epigenetic meythylation clock reset to age 1 could be the basis of transplant tissue.
One way to tell excpetionally well tissue culture tisuue is to use the velvet plate cuplication process; a tissue culutre plate with say 1 billion cyctes at it (vascular epithelium, or better, stem cells) is velvet copied, then the copy frozen (or quiecently maintained), then at the 1 billion cyctes on the source plate actual particular to the human physiological stressors are introduced. For example, blood plasma concentrate from an elederly person might contain the things senolytics get rid of, as well as diverse but nonoptimal immunology, like immune sensititizations; other challenges like hypoxia(ischemia) that would terminate 90% of cyctes, and 99th percentile of cholesteric plaque adhesion. So after one of the velvet prints has 99.9999 mortality, the physical locations of the million cells (stem cells, or differentiateds) that surviced all that are known, then tissue culture is accomplished from just those million cells most likely to thrive and survive found via the physical mapping to the velvet copy base. They would then verify that tissue culture from these 1 in a million best cells actually caused better survival and function at implanted tissue culture constructs, like vascular material, cardiac repair stem cells, and even neural tissue grafts (treating mental things). If it is possible to grind away an atherosclerotic plaque, then spackle the area with the 1 in a million perkiest spackle cytes, then overlay them with a planar tissue made from the 1 in a million perkiest planar tissue cytes, then the repairs addressing cardiovascular disease are likely to be better.
As a possible longevity wellness technology it could be possible to find the “weakest stuff” at a person’s personal tissue sample, then cure it, then deliver the cure to the entire person’s living body for greater longevity from strengtheninging what otherwise would have been the weakest parts. Culture the 99.999th percentile of feeble, (say resistance to ILGF-1, or nonresponsiveness to Nitric oxide, or then cure it, then administer the cure to the actual human where 99.999& of the cells are doing better
Some people, when they exert themselves, experieince cardiovascular events, even while exercise has preventative effects on CHD, implant notices when the person’s physical exertion (and associated things like blood oxygen levels and blood pressure) goes into 1 per 10,000 likeliness of causing cardiovascular event then the implant releases instant destresing, blood pressure reducing, respiratory function optimizing drugs, this is then lifesaving per some number of automatic activations; Opiate peptides might destress, vagus nerve agents, if there are any, might deepen breathing, other peptides could reduce blood pressure.
So this brings up the research question, how many minutes before a heart attack is a heart attack preventable? Do you have to get there 5 minutes early or 30 seconds early? Do sensations radiating along one arm precede a reversible process, or do they indicate an actual heart attack process? 5 minutes early suggests a wearable, like a smartwatch, that magnetically stirs up and opens chemical reservoirs (drug depots) at an injection site beneath it.
The internet says ”The most dangerous times for heart attack and for all kinds of cardiovascular emergency — including sudden cardiac death, rupture or aneurysm of the aorta, pulmonary embolism and stroke — are the morning and during the last phase of sleep. A group from Harvard estimated this risk and evaluated that on average, the extra risk of having a myocardial infarction, or heart attack, between 6 a.m. and noon is about 40%. But if you calculate only the first three hours after waking, this relative risk is threefold.” That suggests that the smart watch that activates drug depots to prevent heart attacks might actually find itself working about 1/2 the time while the person is unconscious in the morning before waking.
One advantage to a magnetic drug depot smartwatch that measures physiologogy and dispenses drugs may be that it addresses the (I pereceive I read) 1/3-1/2 of peopel who have a first heart attack without any medical warning. I do not know what medical warning means, but I get the feeling that it means people who feel healthy, without angina, without prior cardiovascular surgery (atherosclerosis), Have a first and lethal heart attack. Family history could be a guide to whether these people would do well to wear a heart attack preventing watch above a certain age even with a normal physician’s physical. Also, if you omit ever needing it, it omits ever getting used.
“wiggle melatonin” could reduce heart attacks. Noting the connection between circadian rhythms and heart attacks (quoted) it could be that a multimodal distribution of melatonin taken before sleep, rather than a single main dose of melatonin could cause the first 4 hours (highest heart attack risk period) to have some quantitative difference in the likeliness of having a heart attack. Also, there is now a melatonoin-similar-molecule antidepressant drug they could screen to see if it, or, it at certain dosing schedules, reduces risk of heart attack.
There are also nonpineal human circadian rhythm mechanisms and drugs. I read about irisin, whcih effects circadian rhythms, perhaps there could be a heart attack preventing nonpineal circadian rhythm drug.
Epithalon is a pineal hormone, and it is published that humans (over 70?) on epithalon are twice as likely to live six years longer as those not on epithalon. Epithalon could prevent heart attacks.
17%lifespan increase tropical rainforest sounds during heart attack sleep am, measure reduction; stay alsleep massaging bed during am risk period.
“greater than 50 percent more heart attacks in winter months than in summer months, and it's mostly about stress”, combine that with 40% more AM heart attacks and that suggests that studying the physiology of people during summer afternoons could represent a mere 10% risk. So, using rodents, or another heart attack model experimental mammal, inject the rodents with one-previous-heart attack human AM winter blood chemicals, and human PM summer blood chemicals (from one previous heart attack paersons), find out if there are specific circulating factors in human blood/plasma that cause heart attacks in rodents or other lab mammals, interestingly there is the possibility of concentrating the plasma chemicals 10 or 100:1 to get a stronger heart attack production signal. Immunizing aaginst any of these chemicals, if novel, could reduce heart attacks in humans.
if there are specific circulating factors (AM winter) it is possible liver enzymes naturally get rid of them, upregulating those liver enzymes with a pill then reduces the AM winter chemicals, reducing risk of heart attack.
tissue culture staples and roof shingles, tarps oooh gross, or vasculature advantage(?), the tomographed skin tag or wart, possibly from the persons own tissue culture.
Glaxosmithkline: headache reliever pill. Some people chew pills, having planes of cleavage so that the pill fractures all over the place, but always (usually) at a micrometer thin delicious flavor plane turns a yucky chewed NSAID into a tolerably flavored or even flavor treat headache relief pill that works much faster. The flavor cleavage planes could also have hygroscopic (pulls water from surroundings) micrometer coating to form the rapidest micrometer slurry. Better to use a flavor enhanced liquicap though if that is faster at pain relief.
Dwelling air warming, cooling, and transport could be improved as to its effect on indorr air quality. Indoor air quality is likely linked to a reduction in risk of disease possibly heart disease, there is a chance improving indoor air quality reduces risk of heart attack. Noting first four hours of the day (and winter) are greatest risk for heart attacks it is possible indoor air quality duing that time makes a bigger difference. Is there a benefit to producing summer evening psychrometrics (humidity/temp) during winter AM? It is a broad slice, up at 6 am, at work at 10:00, but suggests indoor air quality at communting vehicles could matter a lot, At the dwelling, just running the fan through the air filter 2-4x as much between 5:00 am and 8:00 am could be beneficial,
Indoor air quality and psychrometrics might be particularly testable at nursing homes. Just modifying the settings to a different variety of “normal” (summer evening) at 100K of aggregate residential facility could show a strong data trend rapidly.
There is a chance that summer evenings are actually good for cardiovascularly ill people, rather than it just being ab absence of AM events during winter.Find those beneficial things, then trry them out all year, one possibility is pollen, another is antidepressant long days of summer; better data would be better, I associate winter with rain, others associate it with snow, I perceive places it snows more, the people who live there live longer; rainy winter season from physical rain might be more deleterious than ice season. Psychrometric testing opportunitity.
well lit dwellings summer circadian during winter could be tested to see if they reduce cadrdiovascular events
(circadian rhythms of summer) gene therapy or daily responsive but once annual or less often depot melatonin injecttion could reduce cardiovascular disease. One set of numbers is 50% less heart attacks during summer, and also melatonin or a nother circadian rhythym drug could preclude first 4 hours peri-rising (40%) heart attack risk factor. with a one office visit injection to get the multi-year depot injection/implant
Is hibernation or things like estivation a source of calm and possibly sleep, that might work on completely different neurotransmitters than GABA? If so then this could produce beneficial new harmless sedatives and anti-anxiety drugs. They could take a rodent that does true hibernation, and connect it via parabiosis to a non hibernatining rodent to see if the non hibernatining rodent calmed down, was sedated or also had the brain scan of lack of anxiety. One possibility is the the hibernatining squirrel/rat or beaver combination, another possibilility is testing the groundhog
“While hibernation has long been studied in rodents (namely ground squirrels) no primate or tropical mammal was known to hibernate until the discovery of hibernation in the fat-tailed dwarf lemur of Madagascar, which hibernates in tree holes for seven months of the year.”
circulatory factors of hibernating animals do things to alert animals, “Hibernation induction trigger (HIT) is somewhat of a misnomer. Although research in the 1990s hinted at the ability to induce torpor in animals by injection of blood taken from a hibernating animal, further research has been unable to reproduce this phenomenon. Despite the inability to induce torpor, there are substances in the blood of hibernators that can lend protection to organs for possible transplant. Researchers were able to prolong the life of an isolated pig's heart with an HIT.[36] This may have potentially important implications for organ transplant,”
smartwatch magnetically releases hibernation induction trigger https://www.annalsthoracicsurgery.org/article/S0003-4975(97)00631-0/fulltext “HIT” (or maintenance) chemicals if it detects 1 per 1000 likeliness of cardiovascular event that hour, interestingly it may be possible to combine this benefit with a mild wake-up chmical so the person is able to do something other than pass out in response. bodyside and well as brainside varied chemicalcs could also contribute to heightening surviviving and normalcy after cardiovascular event; bodyside only “HIT” (Hibernation induction trigger (HIT) obtained from serum of certain winter-hibernating mammals, such as woodchucks, 13-lined ground squirrels, brown cave bats, and black bears, can induce hibernation in these animals, even when summer active) At humans, with a smartwatch drug depot this could be continuouous low level medication for those projected to be at cardiovascular risk without impairing mental function. HIT studies are from 1997 and could be updated to see if it is possible to make RNA drugs and peptides that do the same things as the HIT chemicals, thought at the time to be opiods (like opiate peptides)
As a technologogy to get rid of heart attacks, HIT chemicals could be made to circulate at the body during the first 4 hours (most lethal), as well as during winter. Perhaps bodyside only would do it, leaving people’s minds fully functional in the AM. Also, the article mentions opiate receptors as HIT life-preserving drug receptors. I read there are more than 100 neurotransmitters, so perhaps there are other non opioid HIT chemicals that can be found with serum between lab mammals experiments.
Also, they found a primate (nearer human biochemistry, mRNA) the fat-tailed dwarf lemur that hibernates up to 7 months a year, along with opiate HIT, these lemurs may have other serum chemical systems that could benefit humans, particularly at redicing cardiovascular events or making them less serious.
Along with the article URL, that concentrates on treatmentless ischemic hearts having about about 30% their original capacity on survival, and 15 minute pretreated (bear serum or opiates) hearts having 69-80% original capacity this brings up the possibility of using HIT hibernation chemicals to measurably reduce the effects of strokes or even routine surgical anesthesia on mental functioning.
Under hibernation, Wikipedia mentions sharks can go three hours of ischemia, so shark serum could also be tested on cardiac and strokelike ischemia to find new drugs that minimize the effects of heart attacks and strokes.
As a possible technological improvement to the 1997 HIT paper, cell penetrating peptides could concentrate all of the traversal of active drugs (Bear serum simililar chemicals, opiate peptides) to specific organs, for example, heightening concentration at the heart and vasculature, making these drugs more dose efficient and possibly better tolerated.
A one dose approach to a drug that increases the survivability of cardiovascular events (heart attacks) is: tail squiggle gene therapy, photoactive installation just at the heart: Describing that, basically receptors, like opiate receptors have receptive components (one mental reference is g coupled protein receptor swirl fingers) as well as a base area (before the fingers) some authors call the tail that does not directly glom the the thing of interest. This tail area can however have a custom peptide or protein made, that gloms to it, that causes the actual receptor part (fingers) to be more or less sensistive. So engineering a peptide that causes heart opiate receptors (or bear hibernation serum chemical receptors) to be unusually easy to activate and causes them to stay activated could cause continuous “on” status just from normal circulating levels of endogenous (natural) chemicals as they are primed to prefer to be on. One way to get the tails to have the perma-on peptide attached to them, or, perhaps more optimally, just be developed from stem cells with the “easy on” protein sequence and conformation conformation part of their makeup is is phototherapy gene therapy: Using published methods gene therapy only takes (does its thing) where tissues are illuminated, and at a person, cofocal lighting lights up the heart for the duration of the gene therapy installation. That causes the opiate receptors (or also bear hibernation heart chemical survival receptors) to be the only things at the body illuminated/eligible, at that particular treatment, for updating with the new genetic form.
Hibernating Arctic ground squirrels
female polar-bears go into hibernation during the cold winter months in order to give birth to their offspring.
What restarts a cardiovascular event heart? They could put that chamical at the magnetic stirred drug depot smart watch that prevents and responds to cardiovascular events.
circulating null epinephirine with enzymatically cleavable null part then turns to nor epinepherine restarting a heart if the magnetic depot releases a bunch of the enzyme.
radical: EM quarter squeeze a supercapacitor to make a super big current pulse; sequential reaction, 2 supercapcitors, the first em squeezes the second, the second supercapacitor when squeezed has a much accellerated or rather concentratated current pulse. pro IC technology MEMS like size defibribillator,
I have not hard of a defibrillator that installs custom, “ultra high survival” waveforms, perhaps the MEMs duocapacitor could do this as well.
“presented with the shockable rhythms of ventricular tachycardia or ventricular fibrillation (better outcomes)”
People at cardiovascular risk could have their IoT lightbulbs watch them for cardiovascular events. at Quora one person writes, “The most treatable situation is where the event is witnessed, 911 activated and bystander CPR provided. In those cases, we get about 80% to the hospital alive and about 55–60% discharged from the hospital in normal or near-normal condition.”
That suggests that volunteers trained in CPR at various kinds of dwelling buildings could be IoT (Internet of Things) called to suddenly go to a strange apartment with freshly (IoT) unlocked doors to rescue someone before the paramedics can get there. I’d do it, that is I would get CPR certified, then let my neighbor’s computer call me to their assistance to do interim CPR before the professionals arrived.
The cable box anti-heart attack drug flinger and pro-survival taser, expanded to the in commuter vehicle version: I think it is possible that at halfbakery.com I posted a technology about how the home media center (20th century words: cable box) could have a camera that watched the people on the couch in front of them, using things like digital themography of the face to see how their health was. It could spot if they were having a heart attack and then the cable box could discharge (fling) eentsy ninja-shuriken drug injecting at the person’s neck to deliver lifesaving chemicals (drugs), possibly like the ones EMTs (emergency medical technicians) give to people they are reviving, or things like DMSO(drug delivery)-aspirin splashballs, Something better than tissue plasminogen activator, and, having read more recently, possibly the the chemicals at hibernating animals (hibernating bear blood serum chemicals, opiate peptides) that cause (30% functional ->80 functional) greater function survival in heart-attack hearts. The in-vehicle (car) version makes sense as well. A very simple modification to that makes it work better, put it at the dashboard of the vehicle. Airbags are already common, and heart attacks in motor vehicles on the driver’s side (and with oblique shuriken aim, passenger side) could possibly be very near the lifesaving rescue use numbers of collision airbags. The numbers are very approximate, but 2020 800K heart attacks, compared with 30.2K (2010) lethal vehicle acidents, (800k/24 hours, 33K heart attacks during a period of driving 1 hour each day. Note that the 33k heart attacks is spread across the entire population of drivers. If the motor vehicle had an Anti-Heart Attack Drug Shuriken Flinger (AHADSF) only at those over 49 (actually math of a graph with crossing lines could find the optimal age to have an anti-heart attack drug shuriken flinger (AHADSF) installed at a vehicle) then the person could just get that as a standard option on their motor vehicle when they were getting it >49.
Also, there is an opportunity for higher quality of diagnostics than “having a heart attack”, for example, if the radiating one arm sensations that may(?) precede a heart attack can be detected with digital thermography of the hand and neck, then 5-15 minutes of advance notice is produced to fling the drug shuriken ahead of time. Similarly there are optical (laser) only ways to read blood pressure from the eye, and it is just possible that photonics of the face, or through-skull photonics could detect angina. Benefitting this technology is autodriving vehicle technology (driverless cars) which could take over for a person who is on the verge of a cardiovascular event but does not know it, or a person having a cardiovascular event.
One thing an in-vehicle heart attack response technology can do is do a good job imitating an EMT (emergency medical technician), with technology at the steering column able to push out a contact surface that can do CPR compressions, and another item that extends (or shoots, perhaps like a taser) from the steering column that does electrical defibrillation.
https://www.everydayhealth.com/atrial-fibrillation/noninvasive-vagus-nerve-stimulation-shown-to-reduce-atrial-fibrillation-in-post-operative-patients/ "Electrical stimulation of the ear and the vagus nerve that sits on the surface there has a calming effect, in that we are stimulating the largest nerve of the parasympathetic nervous system [part of the autonomic nervous system] and hence the corresponding antagonists," Martin Andreas, MD, lead author and an associate professor in the department of cardiac surgery for the Medical University of Vienna, said in a press release.
For the study, researchers divided 40 postoperative patients into two groups: one-half received LLTS while the rest were given a placebo. The patients who received LLTS for five days post-surgery had a significantly lower incidence of developing atrial fibrillation — 4 patients out of 20, compared with 11 out of 20 in the control group.
“The autonomous nervous system controls the heart rate and influences the threshold for cardiac arrhythmias,” Dr. Andreas said. After surgery, the body is under stress, dealing with inflammatory reactions and oxidative stress, and the sympathetic nervous system — the body’s fight or flight response — gets activated.
This increases the likelihood of developing atrial fibrillation, which affects 1 out of 3 patients who undergo open heart surgery and can lead to further complications.
“Patients who had an episode of atrial fibrillation are more likely to develop another episode and are frequently kept on anticoagulant medication, which increases the bleeding risk and may increase long-term complications,” Andreas said.
A previous study, published in September 2017 in JACC: Clinical Electrophysiology, found that vagus nerve stimulation had a positive effect on incidences of atrial fibrillation post-surgery, but researchers used an invasive device that was implanted inside patients’ bodies. This study shows that a noninvasive option could make a similar positive effect with fewer potential complications.”
As an adjunct that reduces death from CVD vagus earlobe or throat stimulation could be based on a wearable battery pack, with a wireless charging pad on bed. Other published things online have descrbibed how people are at greatest risk of heart attack during the first 4 hour hours or morning (approximately, that includes about an hour of sleeping), it could be that vagus stimulation could have anti-heart attack beneficial AM effects. Similiarly vagus stimulation could reduce cardiovascular risk during Winter (50% greater risk) as well. Perhpas the vagus output of normal well people during summer evenings could be prompted to be produced with a vagal stimulator at the unwell and this could contribute to fewer heart attacks.
I perceive I read some people are not sure if they have had a heart attack or not, perhaps a medical diganostic chewing gum with antibodies that change color could tell people if they are having a cardiovascular event that immediate attention would benefit. The general instructions might go like this: “You have a family hisotry of heart disease and various biomarkers suggesting cardiovascular risk. If you feel funny, chew this gum. If it changes color immediately seek medical assistance even if you feel fine.” This is a actually very affordable, compared to a (color/antibody) $1 pregnancy test, 1 piece of gum a month (the worried well) for three decades is only $360 for a person to test themselves at will if say their hand feels funny or if they get dizzy.
Longevity technology, This one is a longshot. I read that at different times of the human menstrual cycle women are much better at smelling odors than other times. I also read that the abilitity to discern odors is predictive of whether a person will be alive or not. “A 2019 study published in the Annals of Internal Medicine found a link between a poor sense of smell and mortality. Researchers from Michigan State University analyzed data of over 2000 older adults, between the ages of 71 and 82. As part of the study, participants were asked to identify 12 common scents such as cinnamon, gasoline, and smoke. Researchers then tracked each participants over the course of 13 years. As they found, people who identified less than eight different smells were 46 percent more likely to die 10 years laetr. So researchers concluded that a poorer sense of smell could predict death.”, so drawing plasma from young women at their monthly height of odor detecting ability, then administering the plasma fractions as drugs to elderly mice could find out a longevization diference between most effective smelling times of the month plasma administred-as-drug and least effective smelling times of the month plasma-administered-as-drug. Then note the chemical differences between the two plasmas with their different longevization abilities (if any), to find the specific plasma chamicals that are causing the mice to live longer. Make synthetic versions and administer these human chemicals (proteins, peptides) to age batched groups of human volunteers to see if the pro-smell plasma chemicals are longevizing to humans to make a new human longevity drug.
another approach to finding a longevity drug from the human smelling acuity test is to find out the people who could smell just 1 or zero of the scents, and see if their 10 year mortality was above the published 46% for those that smell less than 8 of the samples. If the zero/one smellers are hypermortality-prone then their blood may carry toxic chemicals that when administered to mice cause mortality. The sources (specific plasma proteins) of that chemically transmissable mortality can be found, and then immunizations to those chemicals produced, and the immunizations tested on mice and humans as longevity drugs.
Another way is to make a longevity drug from supersmeller blood plasma: find the 99.99th percentile of both males and females able to discern different odors, then make blood plasma fractions from a donated 2 pints of blood then inject mice or rats with the plasma fractions. Noting the 2 pint volume to mouse or rat dose volume ratio One human supersmeller might be able to dose 300 days of rat possible longevization from 1 pint (600 days from 2 pints), or several thousand days of mouse dosing per pint of human plasma.
(new note)
Industrial and construction lasers could have cameras on them that would only start the laser if the machine saw properly worn laser goggles or glasses on the face
Desalinating water with ultrasound, ultrasonics, the coanda effect and ocean geotextiles; with fresh water at one 1 cent per cubic meter as the output a 11 high identical element stack of water vapor maker, concentrator, and condenser made from corn cob cellulose and some polymers is like a floating sandwich on the ocean, likely near shore; the inner bottom layer of the sandwich is a tesselation of wicking upright dendrites or tree shapes where the wick draw side contacts ocean water, the upper part of the sandwich is a saltwater immune top corn cob cellulose based covering; corn cob powder is $100 per 1000 kilograms on alibaba or 10 cents per kilogram; treatment of cellulose with sulfuric acid or possibly electrode water acid causes the cellulose to turn into a gel, likely compressible, shapeable, particle incorporating gel, a film of the corncob gel plus unreacted powdered corncob is both the upper layer and base lwicking layer of a geotextile air sandwich of a thinckness optimized for coanda airflow, imaginably the geotextile ocean textile is 3 cm thick
Noting a 10 meter long, possibly, standard shipping container the sandwich is on 10 meter wide rolls and shipped uninflated, and the full square kilometer of sandwich is made of swathes 11 meters physically apart, which supports ocean well being by avoiding the anoxia that would come from an uninterrupted square kilometer of ocean geotixtile; at the interior on the sandwich two complementary things combine to make it so air flowing through the middle of the sandwich has 80 times greater humidity, up to 99.9% humidity just a minute amount less than auto condensation of water from air, 1) ultrasonic transducers motionize air in the sandwich sufficient to bring 20 times the volume of air in through apertures or slots on the upper outer surface of the sandwich, and that air is used to provide coanda effect 20 times moving air, 2) the base tessellation of seawater wicking elements provides for 4-11 times greater air humidity for a 99.9 % humid airmass up to 88 times greater throughput of humid air that eventually reaches a nonpowered seawater cooled condenser (liquid water maker); the ultrasonic transducers at the sandwich core are pendant on flaps from above and are shaped to push air axially forward, with the right incidence angle and likely laminar flow to get the 20 times coanda effect air volume motion effect; notably, plastic acoustic lenses exist just like light lenses and along with good design of the ultrasonic elements the acoustic lenses can collimate the acoustic beam for more effective air pushing at much farther distances to push and shape the coanda effect air entrainment, possibly two collimated ultrasound beams would pressurize and push 99.9% moist air which has gone from 10% humidity to 99.9% humidity from traveling past the wicks to the a tube is a water making condenser part; if the humidifier is a sandwich, then a straw angled downward for gravity flow of liquid in-condenser is another part, with interior and exterior of the straw made to have very high surface area internal to the straw and external at the straw with things like nub on a stick cold bringers and heat echangers, including laser velveting of the surface; the straw is a metal powder infused polymer rather than gelatinized pressed corncob powder; although it risks corrosion a 80% magnesium or iron powder fill at the 35 cents per kilogram low density polyethylene could last 11 yearst, and with fe near 96$/ton possibly cheaper than less coolness conductive gelatinized corncob powder; from a simple strawlike tube to an undulating rounded 3d shape the condenser is filled with freshwater from various simultaneous things like the coolness of the ocean, the presence of compression and decompression (slinky) waves from the ultrasound transducer, noting a section of increased pressure causes water to condense and drip or flow to the gravity base of the condenser, and anything that can be done with the entrained coanda flow like passing it through a cooling venturi or what looks like a 3d nuclear plant cooler hyperbolic paraboloid, as well as seeding a genetic algorithm with different aerodynamic shapes, flaps, water-hammer like pressure and thus condensation makers; the freshwater accumulated by each 10 meter wide and optimized length floating component assembly is gathered together from the square kilometer and 11 lvertical ayers and pumped onto land or picked up by watermoving vessels; previously not mentioned is that each 10 meter wide swath of sandwich has 10-40 separate ultrasound flow channels duplicated at it, a meter wide air channel only 3cm thick (sandwich thick) sounds less effective than a 11 cm wide channel; if the floaty sandwich weighs 3grams per square meter (compare various film masses), each square kilometer of 1 million square meters is about 3 million grams or 333 kg, just $34 for gelatinized corncob construction, similarly 11 grams of low density polyethylene could be used at approximately 9 times more, or a little over $300 for a larger amount of a well comprehended material; producing revenue at 1 cent per Cubic meter of water, if a cm^2 will evaporate 1/2 gram of water at 60 F then that is multiplied by 20 from the coanda effect breeze 9n the wicks then each cm^2 gathers 10g of water each 24 hour, or at a kilometer square water production facility 100k sq meters of freshwater, or $1000 of freshwater at a cent a cubic meter per 24 hours, 365,000$ per year, a stack of 11 square kilometers earns 4 million $ annually; if the repairable life of the sandwich and straw is 11 years then the entire thing earns $44 million on $3300 of polymer sandwich plus, at one ultrasound transducer per 20 cm wide times 49 cm sandwich channel, 3 cents for a mass produced but custom acoustic collimating lens, and 1.2-20 cents per ultrasonic transducer (alibaba.com), 7 cents for a localized coanda making waveform generator/power supply, and 3 cents of wire and ultrasonically welded flap hosting the piezoelectric with a front pouch for the acoustic lens, the $ is .4+20+7+3 or 11 to 31 cents per square meter, at 11 cents per square meter a square kilometer is near $111k per square kilometer layer, and 11 layers is 1.2 million $ but earns 44 million $ each 11 years at 1 cent per cubic liter; 1 cent per cubic liter along with benefitting urban persons is cheap enough to irrigate some kinds of crops in sunny locations like California, better versions of this could have the layers anchored far underwater, strongly reducing storm harm risk and placing the pipe that connects all the freshwater containing straws to an ocean or bay bottom freshwater delivery to land pipe and macropump or advanced macro piezopump, possibly earning millions more is to have an upright pipe gathering Santa Barbara temperature ocean surface air and bringing it to the 40-49 degree greater depth sandwich and condensing straw, a 20-29 degree difference, there may also be some millions of $ of fiscal value from pumping the air that will go through the sandwich to the straw through a within 6 inches of warm ocean surface bubbleator/warm air humidifier before it is brought to the sandwich, or even skipping that and just drawing humid air from 16 cm above the ocean surface; electricity to power the ultrasonics comes from the shore; at alibaba piezoelectric transducers come in 1.2 cent forms of about equal mass to the other multiwatt purpose engineered forms, suggesting that the very defined ultrasound transducer linear beam and collimating 3 cent polymer acoustic lens could be manufactured together as 1 polymer pocket sized unit, additionally the corn cob molded gel polymer or low density polyethylene could have smooth flat construction benefitting coanda effect, it is even possible that at an 8 cm diameter channel there could be a short stack of coanda passages for wall effect like(||||||) to entrain air on a rigid polymer gappy linear polywall; polywall or sandwich wall could be made with extra rigid ultrasonic reflectors or cones or other geometries to amplify/concentrate ultrasonic force right where the coanda 20 times air entrainment happens; piezoelectric transducers that are ultrasound range from kHz to MHz, it is highly beneficial to utilize a frequency outside the hearing range of all mammals including marine mammals like dolphins and whales, so MHz has both narrower beam and greater unhearability; on establishing private utilities can actually make money from sandwich and straw technologies they have the opportunity to invest in more durable forms lasting over a century like PTFE membrane, digitally aware ultrasound transducers with a depthy form casting grating in front of them, harmless antimicrobial biocide peptides in the polymer to reduce fouling, condenser straws made from tin coated magnesium filled polymer,
A way of desalinating water so that when it precedes reverse or forward osmosis manufacture of fresh water from seawater only 3% as much osmosis membrane is used, making the two together cheaper than reverse osmosis or forward osmosis alone, first a technology that is similar to a better version; at an STP tube have an ultrasound transducer surround a hollow narrow diameter tube such that when oceanwater is sprayed out of the tube moving compression waves or other ultrasonic and coanda shapes cause the narrow stream of atomized droplets, nanoliters or microliters per droplet to travel forward until they are 94% evaporated; at 94% the droplets strike a wall I will call the brine drainage wall; continuous or even pulsed use raises the humidity of the air in the tube to 99.9% humidity, minutely short of condensation, air is pumped through the tube and the 99.9% humidity air is condensed from acoustic ultrasound pressure waves that cause enough areas of free space air pressurized enough to condense on an unchilled sponge ;Now for the actual different technology; consider a foaming agent mixed with seawater (protein based foaming agent 51¢/kg at alibaba) and the foam it makes, ultrasonically and coanda effect fan it until it mostly evaporates and becomes briny foam with smaller bubble size, then although the actual technology does not use a centrifuge imagine centrifuging the entire chambers bubbles and then setting aside the; a different foam seawater desalination technology has several parts 1) polymer tubes with dendritic wicks sticking out of a tube that carries oceanwater 2) an ultrasonically pumped airflow shape around the wicking tube, at 20 times multiple greater airflow a multiple flat plane geometry is used like [∆] or [ [ ] ], 8 planes at a diamond in a square is 160 times as much airflow in the tube, 3) beneath the 160 times breezy coanda elements is a layer of foamy bubbles that are made with a cheap foaming agent, when the coanda guide ceases all 160 airflow volumes of moist wicked air are directed at the foam layer; the foam layer then surface absobs the water vapor rich coanda breeze air; when the bubbles moisture, determined by spectroscopy or just predicted with timing, has been re
placed with 97% freshwater a phonic or ultrasonic all bubble popping event occurs and the 97% freshwater is pumped to an osmosis filter to purify the remaining nacl mgcl2 cacl2 out; ultrasonics drive the coanda breeze
With ease of laser cutting it could be that lightweight metal or ceramic replacements for wood are possible, cheaper than 2021AD wood lumber, and much longer lasting a few forms are made on site ceramic pieces from laser sintering of cheap ceramic powder or ceramic lumber factories at areas with lots of cheap electricity or natural gas; genetic algorithms would find optimal internal structure like geodesics, vaulting internals and screwdrivable, nailable drillable forms; that form could be a lumber core that is then cooled and slid into a ceramic or metal sheath/outerlayer/girdle for greatest durability; glass beverage containers are cheaper than ALU!inum so an ultrasonically foamed liquid glass or ceramic could be especially affordable, perhaps foamed around a cheap green ceramic molded geodesic Where the ceramic lumber is then heat treated to ceramicize (cost similar to concrete thermal calcination), other ways to make cheaper than wood ceramic or metal lumber is to make two mateable sides, like stacked bookends or stacked ice cube trays making the linear lumber replacement fit together like two ]] brackets and using ultrasonic or laser spot welding that cofocalizes through the exterior to weld multiplenums inside a lineal lumber boxbeam together giving more strength than just a hollow boxbeam, at a welded brackets form genetic algorithms are used to find optimal strength with least mass and greatest ease of munufacture; it could be that rather than vertical wall plenums, angled plenums in a polyribbed shape surface or asterisk are better, the genetic algorithm improves the box beam filling; at ceramics foam is possible and could greatly reduce weight, large cell double thick walled larger diameter foam bubbles may be possible to produce from ultrasonic and simultaneous treatment that produces cavitation at a spreader nozzle that either fills a mold or draws a lumber shaped bolus on a continuous process conveyor belt; low (sodium silicate) or high temperature glasses and ceramics can be used for cheapest manufacture; other kinds of wood replacing lumber are producible this way like ceramic or metal plywood, metal version might be butcher block ice cube tray, ultrasonically welded or laser welded plenum construction or anything the genetic algorithm likes better, notably at laser welding, and possibly at ultrasonic welding entire square meters of material can be welded in parallel with a light distribution grating like a hologram that simply spot welds all ]] plenum walls with minimal alignment, industrial lasers are published as join welding 60 meters/minute, which could be multiplied several times over as the massively multiparallel plenum spot welds are much faster
The metal to make a linear lumber or plywood replacement seems to be ferrous alloy, zinc or new conductive polymer anodic protections would be used, at a construction site a drone could beam radio at a wall or building and compare it to a the image or the cad plans to find any ungrounded metal at the buildings metal lumber to connect to anodic protection
Comparing an explosive nailgun and an explosive rifled barrel screwgun that shoots with a twist, rotational rates that are multiples higher than the directional force could shoot screw-capable screws, useful at metal lumber
My perception at plywood and oriented strand board is that the urea glue is cheaper than the wood, only if that is so then genetic algorithms could come up with a new form for all urea glue paneling, ultrasonic and laser foaming might be very cheap, and embossing surface ribs is also cheap, although plywood is a laminate minimizing the amount of laminations makes all glue plywood cheaper, noting the polymer expansion pellet like styrofoam, peraps urea wood glue expansion pellets could be made to make a new kind of strong light styroboard where different space filling geometries or pellets are combined, like long foam straw lzser oriented nonwoven fabric layers, at alibaba aluminized mylar is 1\2 cent per sqfoot, suggesting an aluminum, or bismuth or tin moisture blocking metallization can be less than that
Could soliton like high energy dissipative solitons be better at drilling through earth for wells and petrochemicals, farm soiltreatents and sewage leachate fields and colorization layer of reverse osmosis membranes
Using ultrasound to make roofs last longer, at a roof like a polymer coat flat roof there are areas of water concentration some might be puddle like, the effect of putting an ultrasound transducer and vibrating form in these puddles is the cool ultramicrospray of water out of the puddle at a velocity comparable to an ultrasound humifier, this takes much less energy than it would to evaporate the puddle, so as a roof technology a 1-2 watt piezoelectric transducer, a polymer or aluminum vibrating plane an either a 1 or 2 watt photovoltaic or a rooftop electrical plug powers the puddle remover; for new construction of bulbiform, angled and flat roofs the ultrasonic elements can be made a part of the roofs layers or top, each 1000 sq meters of roof might have 1kw of spread out transducers, run for an hour or less each day, and contain $200 of transducers at 20 cents per transducer; it may also be possible to use 1\10 the energy and number of transducers from putting them only at low wet spots at the edges of eaves and height reduced areas of flat roofs
Wikipedia describes ultrasonic trills as using just 10w to drill a hole in granite compared with 760w with a rotary electric drill, that suggests that boat and ship propellors like those used for containerized shipping could be more energy efficient with ultrasonically agitated or even driven (rotated) propellors perhaps causing 76 times less drag, similarly kW of ultrasonic energy at the leading point of a ship could ”drill" throughwater 76 times more efficiently; applied to pumps like air conditionimg amd heat pump pumps as well as agricultural pumps à vertical translation rotating 8mpeller that rides a focal cone of ultrasound (see wikipedia ultrasonic drill) or is ultrasonically linked to a vibrating mass that twirls could use much less energy to recompress refrigerant or, at agriculture, move water, and at industrial pumps move industrial fluids, i do not know of any water propellors or pumps based on the wikipedia ultrasonic drill developed by NASA; I perceive the thicker the solid or liquid the nearer the technology is to the 76 times efficiency gain, that suggests an ultrasonic saw, simply a line of ultrasonic drills could replace diamond tip circular saws at construction and roadway concrete cutting, metal cutting and, at industrial cutting the equivalent of blades that omit getting dull thus last longer and have less maintenance, what is called stir-welding could also benefit from ultrasonic drill technology, producing, like granite, 76 times greater stirring rotating perhaps percussimg amount of stir welding for the energy used; the ultrasonic drill technology's effectiveness at drilling an inch in granite with 76 times less energy has direct functionality at transforming above ground or below ground ore chunks around 2-3 cm into powders and microfine powders for smelting and leaching ore, at mining, similarly if an ultrasonic grinder is based on ultrasonic drill technology cement and concrete clinkers can be powderized for use much more energy efficiently; wikipedia notes after 1 inch drill depth mineral fragments and powders effect drilling effectiness, blowing the fragmented material out with the coanda effect or a simple water jet slurry are likely to increase drilling depth; I read about an amorphous compressed fullerene glass more than 1000 times harder than diamond, that could make an especially effective ultrasonic drill, saw, or grinder active element coating; the efficiency of the 76 times more effective ultrasonic drill could be increased from customizing the kHz/MHz frequency to the ores being powderized or the thing drilled; also wikipedia mentions one part of the drill is a vibrating mass with the drill bit on one side, if an ultrasound acoustic reflector is used then both sides of the vibrating masses wiggle can be used, visually a little like a ballpoint pen receiving energy from inktube and also angled-in ferrule around the ball of the ball point pen image, also depending on the material being drilled or the ore being powderized various ratios of percussion:rotation or even eccentric motion produce different effects at the same energy, it seems to be possible to double the energy efficiency of the ultrasonic drill, saw and grinder; its easy to think of an ultrasound crystal as an electrode sandwich, but what if the piezoelectric element were molded or laser cut to look like an undulating rollercoaster or a center connected group of chevrons>>>>, then the wave emitted would have additional 2D or 3D character and with different electrical connections at each swell of the roller coaster or separate leaf of a polychevron the ultrasonic crystal could separately and compositely addressed; is the vibrating mass mentioned at wikipedia high density and highly affordable like bismuth
The way a rotary electric drill is often a motor, and a motor swaps for a generator, but is 76 times less efficient at drilling than an ultrasonic drill suggests the possibility of an electric generator or motor that produces energy or travels further an order of magnitude better than an electrical winding machine if the generator is built to precisely and frequently strike/deshape piezoelectric elements that have conductors on them to produce piezoelectricity, a rotating turbine like a gas or nuclear turbine could pressurize an air or even water whistle tuned to the optimal receiving frequency of the physically connected piezoelectric crystal, an alternative to a whistle is a super purposefully very loud slippage of metal on metal, like the idea of a squeaky bearing amplified, another source of piezoelectric sound is a rotating bike wheel with thousands of radii wires as strikers to a plurality of tuning Y objects encruested with piezoelectric crystals, or each being a single wired for electrical production crystal each
Motion coupled piezoelectric elements could function as very high efficiency transformers benefitting the many transformers at an electrical grid
Ultrasonic anti-ultrasonic drilling at bearings and piston rings, can an anti-drilling effect make a bearing or ball bearing that floats in the middle of its tolerance range, causing much greater life, does ultrasonic jiggling reduce raceway friction if the jiggle moves the bearing or ball bearing towards central location of least contact, reduce friction and warmth generation
Noting that lasers can etch surface finishes it could be that an agricultural drone laser that purposefully thins the outer upper cuticle of agricultural plants leaves to make them thinner and have a grating would cause them to absorb more irrigation water and spray on nutrients, fruit, nut, soybean, grain crops could all be tried with this, it also increases gas exchange, really unlikely possibility is that with laser cuticle thinning available CO2 goes way up; just as gratings increase the optical transparency of metals the laser ruled gratings on plants could increase transparency and be like an antireflective coating from reshaping the cellulose on the leaf, broad massively multiparallel etching of 2x2 meters of surface at a time could be done with a hologram grating and strong laser aimed at a swath of plants, using heatless pulsed spallation lasers is also possible
Lasers could be used to smooth out bumps on roads with laser planing of asphalt and cement, making drivers happier and possibly slightly increasing energy mileage; the road laser planer could have a new road stripe painter on the same platform, airjets or rotary sweepers could sequester and remove the planed away micropowder
Do geodesic molecules like fullerenes exist but made of silicon?
(new note)
Treon Verdery <treonsverdery@gmail.com>
May 6 to 14 technology notes
Treon Verdery <treonsverdery@gmail.com>
Fri, May 14, 2021 at 12:41 AM
To: Treon Verdery <treonsverdery@gmail.com>, Be An Angel Be An Angel <beanangel300@yahoo.com>
technology ideas that are new to me May 6 2021 to May 14 2021
New technology ideas:
,5b, "The thing I don't get is that propellors were initially multi-turn helices, but were found to be more efficient as the helices got shorter, down to the point of being blades a fraction of a helix long"; this reminds me so much of power transmission with a circularly polarized wave and a polarized antenna I am amazed.
better transmission of RF energy: math:trumpet of gabriel shaped waveform; trumpet of gabriel shaped antenna concentric circle pickup antenna for trumper of gabriel shaped EM waves
Longevity technology: stem cells, like induced pluripotent stem cells (IPS) from xenocompatible bowhead whale tissue culture: I read that bowhead whales live over 200 years, so building replacment human tissue from bowhead whale stem cells could increase lifespan as well as make stem cell renewal and repair of things more durable. As to xenotranplantation I read that they had engineered a pig to grow xenocompatible (human compatible) entire transplant tissues and organs. I think that just engineering the not-a-whole-whale stem cell tissue culture is sufficient to make xenotransplantable bowhead-to-human stem cells. They could see how it works its repair effects, durability, and any lifespan increase on mice. Therapies involving using stem cells to repair or renew the human brain could benefit for supercentenarian stem cell progenitors. This is perhaps better at replacement neurons than bowhead whale neurons.
sex technology: robotic surgery penis lengthener. This might not work as I have not heard of the human surgeon version of the procedure:
sex technology: robot surgery penis lengthening: the penis seems to be rooted at some depth, and if it were detached from its basehold would float free from(inside) the perineal area; after making the penis float free you could pack the newly hollow space at the interior base of the penis with some kind of biocompatible polymer, and leave a "new, higher planting hole for the tree", that is a heightened base to stitch the base of the penis back onto to stabilize it. Once the penis is healthy and physically robust enough at its new location the person can have sex with their penis that has been lengthened 1-3 inches. technologies supporting this are artificial ligament technologies, and activating chemicals at depth with lasers to promote growth like EGF, HGH, NGF, others. A robot surgery version of this makes this much more affordable for more poeple to voluntarily use. I favor germline genetically engineering all humans such that pubertal and post pubertal males to have 8 inch long, 6 inch girth penises, making this robot surgery unnecessary.
Its my (unfounded?) impression mice might live longer if they get frequent mating opportunities, both sexes, without pregnancy; if this is true then it could be things like olfaction of fertile females and "alpha males" that causes the longevization at mice. If there is a group of scents that cause mice to live longer they could find out what mRNA profiles are different betwen the scent-receivers and un-intervention mice; those mRNA profiles could have clues as to what proteins are occuring where to cause the greater longevization. The genes that code the longevity increase from beneficial olfaction are likely to have human analogs/homologs; they could give marmosets RNA drugs or gene therapy to imitate the longevity gene activation and measure the longevity increase, if any, at primates. IF it longevizes marmosets it then becomes a longevity drug for humans or a longevity gene therapy.
there is a methylation clock (epigenetic clock) that forecasts and shows aging. Has anybody tried simply rewinding the methylation clock to say age 14 years old (or younger) to see if it causes greater longevity, they could test this rewind of the methylation on marmosets as well as mice; notably if putting the methylation clock back to age 14 (or younger) causes greater longevity at primates it could be tested as a longevity therapy in age batched groups of humans, then if that is functional a one pill methylation epigenetics clock rewind pill. a single office visit, or just one pill ordered online or available at groceries is then a longevity treatment. along with the methylation clock there might be an acetylation clock and a ubiquination clock, all under the name epigenetic clock https://en.wikipedia.org/wiki/Epigenetic_clock
1/4 - 1/11th per STI test cost sti test kits like those from from china; sti test kits are variously $5.50 (a number of STIs) or $3.50 (HIV test); I think just 1/4 the active cchemical area could be used ot make a STI test kit that is $1.32 (multi) or 88 cents (HIV); one way previously described is to have a polymer magnifier bead at the testing cassette (turn the thermometer giant line effect) or two chemical overdevelopment; two antibody overdevelopment is well known in antibody staining like antibodies to antibodies, this plumps up a much narrower less visible line; antibodies to antibodies could contribute to reusable/multi use saliva tests and pee tests. Repeat usability: One possibility is simply having say 4-11 peel off stickers, under each of which is a fresh antibody line exposable for saliva or pee. That makes the cassette reusable 4-11 times saving costs on individual test cassettes and urine cups. That could also be applied to developing world STI tests, where one person gets the test, and then shares it with multiple partners (one HIV test can be reused on your next 4-11 partners before you have sex with them. The cassette could have near flavorless amounts of Quats in it to steilize it between licks, considering 4-11 people might be licking the cassette. in fact if the whole test was made of blotter paper and cardboard, licking the sides of the sample chamber unintentionally would mean licking paper, and the paper could be saturated with quats to automatically sterilize any liquid that got on it, without effecting the test results. The very cheapest form would look like a white cardboard rolled lollipop stick with 11 saliva color test patches on it, each under a peel off sticker for 11 separate tests; the paper stick is suffused with quats to be autosterilizing. The lollipop stick is like to be 1/100th-1/1000th of a cent at alibaba, and the antibody color patches, if STI test color change antibodies are 10 times more than the cheapest $435/gm antibody online (then they are$4350/gm) suggest 10 micrograms of antibody for the colorant could be a test, and 110 microgram of antibody covers 11 tests; that is about 1/10th of a milligram so that makes 11 tests 43 cents, or 4.3 cents per HIV test. The form factor with just 4 HIV tests on one stick could be more popular at only 18 cents for the 4-test stick packaged in cellophane. I suggest it be deliciously flavored (isosafrole, or new chemical similar or high potency halogenated isosafrole molecular variation (splenda is chlorosucrose) (chloroisosofrole might be flavor magnified))so people look forward to that flavor again.
embossed parabolic bowl on metallized paper with dots of colorizing anitoby test antibdoy at the optical bowl base; this is a visual amplifier
Sex technology: bremlanotide makes MCR4 and MCR3 receptors activate, gene therapy that doubles or triples the amount of MCR3 and MCR4 new recepetors produced at the body, so is a sex drug that takes a little while to work, but then could triple sex avidity. receptor mechanics improvements; MCR3/4 triggered by much more common endogenous chemical would cause people's sexy to be turned on much more of the time. I think I previously described RNA drugs to MCR3 and MCR4 as sex dugs, and tail-nestling peptides that change docking ability as sex drugs.
Longevity technology: heart attack preventative: heart rhythm drugs, things like "elogated QRS interval (made up): are thought (published as) bad, so does that mean there is a large pool of heart rhythm variants that are considered good, like "shorter QRS interval" that are the inverse of the "bad" ones; they could make and install a bunch of the "good" heart rhythms at one time in one pill and then see if it caused people over 50 to have less heart attacks and less serious heart attacks.
Sex technology: there is a patent on a magnetic spine location stimulator that causes sexual snesantion from stimulating the spine. A simple technology is an adherent patch on the back at theat point with a battery and an EMF coil that is activated by software that detects when a person, such as a woman, is about to have an orgasm, the magnetic sex stimulator is trigggered, at various waveforms (high pulse, flutters, etc) and the person is either pleasnatly accelerated to orgasm of just has a better orgasm. Acceleration to orgasm could be used by software to facilitate simultaneous orgasm with both partners wearing adherent magnetic pads. The pads would be rechargeable. Previously described at paper notes is msart speaker technology like Amazon echo Dot or Cortana to listen to and video view sex to offer unobtrusive but effective sexual pleasure suggestions, this is software and magnetic soft applaine to make that more effective.
Longevity technology: previously described is how at one pill, an epigenetic therpay can increase lifespan. Another one of these could be the epigenetics of a spercentenrain-related 7 year old compared with the peigenetics of a 7 year old related to a 1th percentile of lifespan family; The difference between the two epigenetics could be an epigenetics of longevity, and they would test the human epigenetic shift to supercentenarian 7 year old epigenetics on marmostes (a primate) to verify they caused greater longevity. The epigenetic changes could be packed into an oral pill with RNA drugs doing the epigenetic modification or a one-time, no-physician needleless autoinjector (similar to a collagen injector on Ebay). Another one time epigentic therapy is the difference between a 7 year old super centenarian relative and an adult with 1th percentile family longevity history methylation, acetylation, other epigenetic difference; the epigentic difference is tested on age batched marmosets as well as age batched groups of human volunteers to see if it longevizes them, if it does it can become a human longevity drug. If it longevized them a lot it could be a germline gene therapy enhancement, that makes RNA epigenetic drugs that adjust epigentics at the human throughout their existence.
.5b content, responding to [wjt] ideas:
Looking at IR camera on wikipedia I found out about hyperspectral imaging, it might cover this pretty well.
Also, if you think of less-than-heat (bigger than heat) you think of jiggling everything from brownian motion to a mitochondial membrane (wall) vibrating in place a little.
So, synchronize microscope vibrations to cells to see clearer of chracterize natural jiggling motions:
I have read about AFM stages that can position with picometer (!) accuracy. As a new technology, causing the motionizing of these microscope stages to vibrate at various <--> and up down frequencies could reveal the simultaneous vibration direction and amount of cell structures by making the imaged thing, like a nucleus come much higher into focus, or go out of focus in a predictable way from different stage-added vibrations. This could be used to map the vibration of organelles and cytoplasmic contents all over a healthy cell and is similar to, but different than [wjt]s temperature mapping.
wiggle-jolt-focus stage
— beanangel, May 07 2021
[blissmiss] I'm so glad you got to experience psychedelic mushrooms. I miss them, although there are kits on the internet to grow them.
[wjt] I could see this working on Etsy.
— beanangel, May 07 2021
[2f] Have you heard of a halback array, it makes a strong pole on one side, and minimal magnetism on the other side; so is there a 2D (planar) halback array, and really interestingly, a 3D stacked halbach array, perhaps a little like your pyramids, but optimally some other shape that ///\\\ overlaps or "focuses" the magnetic pole to higher power. Computer modelling of magnets with physics software and genetic algorithms could design this even if it seems a big thing to humans.
Pole pieces designed by a genetic algorithm for the interior of a magnet could be your "bulking agent" that makes magnets more powerful.
[wjt]: pole pieces in the magnet: pole pieces shape magnetic fields, causing local intensification at the pole piece; your optimized magnetic domains could be interspersed with pole piece material (at improved manufacturing) to, just perhaps, cause greater magnetic strength from interdomain communication.
Also, as to super strong magnets consider an image of a bulk magnet slice that looks like a tessellation of hexagons. Using better manufacturing (like IC lithography) replace some of the hexagons with an individually addressable electromagnet, then there is a landscape where with induced electricity some of the magnetic domain hexagon spaces can be 100s or 1000s of times more magnetic when inductive power activates their microelectromagnet; this causes new effects at the magnet, and makes a new kind of MRI (NMR) magnet for scanning. That is a little like making your passive "bulking agents" able to switch between no magnetism and much more than material magnetism amount.
— beanangel, May 07 2021
I like the idea of doing stuff to individual atoms to see if it effects radioactive decay. There's new stuff to do all the time:
The delayed quantum choice eraser uses laser optics to do something that some physicists call "retrocausal", others call "heralding" and other say different things about. At the retrocausal interpretation making the beamsplitters and lenses out of radioactive material could possibly catch retrocausality at radioactive decay, or cause delayed radioactive decay. If it is possible to devise a "time speeds up" variant of the delayed quantum choice eraser experiment then they could see if that accelerated radioactive decay at actual radioactive atoms in the optics; similarly the delayed choice quantum eraser experiment was done in air, so that suggests a radioactive gas, and laser immobilized atoms, could be at the retrocausal physical point (if there is one; retrocauslity may be spread across the entire apparatus) or a few atoms from it.
radioactive bose einstein condensate, with one technetium atom, what happens to it when the technetium atom predictably decays? I do not know.
As to effecting radioactivity I think the strong and weak nuclear forces are associated with nucleus "cohesion"; that suggests any space in the equations to effect those could be a basis for more "spanners to throw" at the atoms to see if they change.
If you wanted to run a very thin atom through a very thick atom you could accelerate protons to 99.9999 percent of the speed of light (routine), and then have them meet atoms in a different frame of reference that did not experience matter compression (foreshortening) from relativity; the thin disc atom would "scan" through the stationary atom it was "not colliding" with, and other atoms quantum entangled to the scanning thin disc atom might change based on what they reacted to at the interior at the plump atom.
Just thinking of it, quantum entangling [linking] a bunch of photons to a proton, accelerating the proton to relativistic thinness, and using the linked proton beam, spray, or dribble to scan matter at depth could actually find the chemistry of various things to the depth of material or tissue that a relativistically accelerated proton can go; a new kind of scanner.
I think there's something called IT pattern resonance, it is possible that radioactivity might occur at different velocities in live humans, uninterred car accident remains, and interred (buried) bodies. This would be easy to test with voluntary isotope injections of very aged people in nursing homes expected to have less than a year to live. If it is findable, then that would be big news.
— beanangel, May 07 2021
perhaps dominos and mousetrap balls with energy-space variation as [wjt] describes could be used in some standard way to make rulesets and seeds for automata, like non- turning cellular automata (some of which look like cross- reactive dendritic trees).
This makes me think 3-D packed (multilevel, but why have levels) Computer models of processes, especially chemical processes, among them petroleum refining processes.
— beanangel, May 07 2021
I thought of a completely different and closelly related item last night. Driverless cars see other cars and predict them, the earlier and more accurate the prediction the more time to adjust the driverless cars angle and velocity.
Driverless cars could look at human drivers of other cars for tells, that is perhaps there forearm moves slightly before the turn signal is activated, and perhaps the first 2-3 inches of steering wheel moves before the car moves. In my mind at least I had AI observing (other) drivers through their windshields up to a full second of extra notice for movement surprises.
— beanangel, May 07 2021
([wjt] at halfbakery suggests using tissues to do antibody colorimetric diagnoses, that suggests improvements): This could be good for telemedicine too: You just hold the used tissues, or tissues up to the screen for your doctor to look at and she interprets say a 3 color color code from the used tissue to be any of 340 different illnesses. Or, better, software watches the telemedicine session in realtime, spots the used tissue, and deduces the nature of the illness from the colors on the tissue, informs the doctor, and then the doctor switches to asking questions about that particular illness.
I have calculated colorimetric antibody staining can be less than 4.3 cents a test, so a pack of ten tissues, with a binary-tree out of illnesses 4200 deep is just 7*4.3c or about 30 cents a tissue, a mini-pack of ten tissues mailed to every HMO client could be just $3.00 excluding postage and improve telemedicine, and increase its use.
Also, no runny nose? Just expectorate on the tissue.
— beanangel, May 07 2021
-colorimetric wet wipes might be able to learn something from skin; vaginal mucous or male ejaculate colorimetric diagnostic could also be useful.
[wjt uses title "dolphin memes": I was thinking this might be about super pleasant super enjoyable to the dolphins Memes (Dawkins variety) that autopropagate among dolphins. One possibility is playing dolphins say 700 different 60-90s song intos, and choruses, and seeing which ones they sing to themselves or sing back. That could be a starting point on encouraging dolphins to sing. Then, you could use a genetic algorithm to generate new intro sounds and choruses, and see if any were super appealing to the dolphins.
Scientists could measure, and be pleased at, not only voluntary dolphin singing of music, but finding out when they made up variations, that is, dolphins composed music.
It might at first seem like dolphins might have their own pre-existing form of music, it is just that various Western forms of music (classical; Pachelbels Canon for Dolphins), and 60-90s top 10 music reached across many cultures to become popular. So, dolphins might like it.
Also, I seem to remember reading that dolphin communication can represent 3D shapes; that is, like a volumetric finite element analysis (FEA) model; dolphins might make 3D classical music if introduced to it.
After identifying dolphin songs, and song intro variations, versions could be made of dolphin songs for humans to enjoy.
As to the creation of 3D FEA dolphin memes, computers could assist with that, like genetic algorithm variations on seeing an enjoyable plurality of fish or sexual play; as well as come-hither vocalizations of dolphins prior to sex, and sex play. the genetic algorithm, and software might repeat motifs spatially (more fish; more sex; more good mood) sort of tesselating things dolphins like.
Also, they could feed dolphins MDMA, spatially record their vocalizations, and use those happy vocalizations as a genetic algorithm basis to develop Happy dolphin phraseology for use in producing autopropagating memes and what might become dolphin song lyrics.
— beanangel, May 08 2021
Dolphins: Along with that, dolphin memes might teach where fish are located, and at a human dolphin benefit, drones could fly over the ocean, do fishfinding (dangle an ultrasound thing in the water even though eirborne), and internet-to near dolphin drones that reports to dolphins on where the most nearest fish are. This could make dolphins even more well fed and increase the numbers of dolphins from nutitional sufficiency.
better wire makes better generators and motors and completely new devices: responding to [wjt] https://www.halfbakery.com/idea/FLUED_20wire :[wjt] I think I get it, and I thought of something similar once but not the same. One thing you may like is carbon nanotubes as wires; these could be decorated with attached groups, intensifying with the actual physical curve of a winding wire at a generator or motor. ==^^==^^==, but of course you FLEUD wire has more going for it.
Here's a thought for you, if a proton conductor (nafion polymer) is sheathed with a conductive metal layer, does electricity complement protonicity to do new things? Do the protons follow the other handed rule, and the electrons follow the right hand rule, at one composite wire simultaneously; what does the mathematics of that suggest as to completely new devices? this could be a way of packing more electrical potential, or even electromagnetism into wires.
I have never heard of a person making a generator or motor or electromagnet with proton conduction before, but it should be possible.
— beanangel, May 08 2021
longevity technology: the epigenetics of protecting against aging could be found, for example, if progeroid genetics are at the mouse, then epigentic variations can be tested on mice to find which most reduce progeroid symptoms and cause longest lifespan, even with progeria. These protect aginst aging epigentics could be thought of as different than other "upregulate or downregulate" to cause greater lifespan genetics and epigenetics.
Also it may be possible to deflect the accumulation at the methylation clock (epigenetic clock) by changing the genes that cause methylation to occur. It is likely there are better ways, but simply downregulating methyltransferases (or whatever epigentic methylator gene products are called) by doing an epigenetic "turn-down" of the methylators; HDACs and removal of acetylation at genes that methylatate are also possible ways to do this.
Long duration tissue culture of supercentenarians; compare median lifepsan tissue culture to 99.9th perceptile of longevity tissue culture, extending the tissue culture out a century past the human's not being alive; this finds genes and epigentics of super long lasting cells and tissues, that notably are healthy and youthfully functioning even at mutlicenturies of tissue culture propagation. 11 mouse lifetimes of transplanted tissue healthiness; It oculd be that many humans are already filled with millenia lifespan tissue its just that cardioevents and cancer and pneumonia take them out; verify and improve milennium lifespan human tissue types; find engineering-like nonprogeroid ways to mimic advancing age, perhaps 1th percentile lifespan persons epigenetics and genetics, to find differences amongst human cells and tissue to find the genes that cause the milennial lifepsan human cells and tissues. This could even just be tissue culture warming to above 98.6 but before instant termination;
Longevity technology: RNA drugs edit epigentics to produce most longevizing epigenetic form, place the production of those several RNA drugs simultaneously at genetically engineered globe-spanning, differnet species, weed plants, that way one dose causes epigenetic change to longevization at any person or other animal (such as mice, deer and rabbits) that eat the multiple species of globe-spanning weeds. Engineer the epigenetics modifying plant to tast delicious (perhaps oil-producing with sweetness peptides) also engineer grass and grass seeds to make the longevization RNA drug suite. This also supports Dave Pearce Hedonistic Imperative as well as Abolitionist manifesto benfitting as it does nonhuman organisms as well as humans
It pattern technology: softare finds and observes the actions of people functioning as Q, porting people between what to me seem like overlapping world-forms, The software then finds shared features of Q behavior, and any Q contact with the person being ported, and then makes a software and robot based Q equivalent functionality that exclusively ports people to what JY calls the first world. Internet software screens people's postings and content, social media to find persons that are likely to be at other than the first world then gives them the volutnary opportunity to be ported to teh first world. genetic algorith of contact/advertsing phrases for being ported to first world are generated to find the most persuasive, but It pattern white, positive upside only communications to get people to volutnarily be ported to teh first world. It might assist things if the computers that do this have a coating on their integrated circuits that is cobalt blue.
[wjt] writes at halfbakery about unmeasured effects at particle/wave slit apparatus; I'm really ignorant, but could a continuum of soliton to highly dissipative photonic pulse improve understanding of the double slit experiment and produce new technologies;
basically see if solitons caused greater or lesser likeliness of a particular W/P version: do this at a particle/wave apparatus that is optical bench adjusted to always have half the observations come out particle, if there is any variation in waveform that causes say a shift to 60% from 50% that would be new to me, and could perhaps be informative and technology producing.
It is likely already published but what is the effect of putting 10,000 simultaneously quantum entangled (linked) photons through a 50% particle double-slit-like apparatus; it could be that if the first photon gets either W or P treatment all the quantum linked photons that subsequently meet the detector are "cajoled" into identical W/P identity causing a 10,000 event data homogeneity, very detectable and far different (99.999%) than the 50% that would be expected from the apparatus. that could suggest new technologies like improved laser detectors at photonic internet (quantum entanglement improves detectability, permitting further apart repeaters)
More data capacity, beyond the data capacity of bits with entangled W/P effects: It is possible quantum entanglement could cause additional data space to be available at photonics above and beyond the mathematical data capacity of binary (0/1), that would make a data representation and computational basis that actually stored and contained, more information than just bits, and exceed what I perceive are the writings of Shannon on how much communications space is available to a system.
— beanangel, May 08 2021
energy saving, comfort producing white paint: It is possible that painted walls, as-is absorb IR rather than reflect it, but if the paint reflected almost all the IR, the temperature of the room would go up to human comfort levels, requiring less energy to heat. So, IR reflective white paint could increase comfort.
response to [wjt] at .5b: If your idea works then it is possible specialized drones could take to the cloud layer, oscillating their velocity to produce weather-changing sonic booms.
Fortunately I read that at new supersonic aircraft plans they have ways of focusing sonic booms (focusing is also good for you weather control application) to be quieter on the ground. So perhaps your weather modifying sonic booms could be focused for optimal weather changing intensity and undetectable to people.
Also, noting [lurch] comment about a bow wave, would a rotating screw (looks in my mind like a camshaft) right at the leading vertex of the aircraft > cause pulsatile ripples of sonic boom-ness as the aircraft oscillated its velocity?
Another application is making it so cities and towns have sunny weather during the daytime
— beanangel, May 08 2021
MRI friendly antibodies and aptamers: Longevity technology: these glom onto things but are themselves hypervisible and digitally unique whether from unique compostion (perhaps the aptamer has a magnesium atom, gadolinium atom or a fluorine atom, other atom, or a quantum dot as part of it), an unusual isotope, or a special protein shape. theme make it super visible at NMR and MRI, like fMRI, as well as photonic imaging. These increase resolution of imaging and can be used to map wherever in the body the antibody concentrates; so to promote longevity, hypervisible antibodies to senescent chemicals could be made then mapped as to their locations in the human body. researchers could then think of treatments that verifiably reduce senescent chemicals, cells, or tissues with imaging doing the verification; One simple possibility supported with published anticancer technologies is that locationally targeted (cyte type, tissue, organ) gene therapy or epigentic therapy is used to decrease those cells, tissues, organs amount of sensescent material. Enzymes linked to loosely glomming antibodies or aptamers could cause enzymatic tranformation of the thing or protein glommed to a non-senescent, or at least neutral form.
Longevity technology: find the difference in genetics and epigentics among that with senescent tissue/cell maps at variously the 1th and 99th percentile of minimal senescence, as measured with 3d sensecence mapping (like MRI labelled sensecent antibody aptamer mapped); Also, it might be that senescence always show up concentrated in some tissue, organs, or cyte types and not in others: find unusual people with novel locational patterns as well as different people with lack of senescence at commonly senescing cells, tissue, and organs. The combine the senescnet mapping-unusual with the 99th percentile non senescent to prodcue least senescence, at least places genetics and epigenetics; gene therapies, germlne gene therapy, and epigenetic drugs can the be used ot give humans the biology of least senescene, and where it occurs, it occurs in teh fewest places.
Brain youthfulness longevity technology: use senescence mapping with hypervisible-to-scanner senescence antibodies and aptamers, possibly at lab animals with a temprarily super-leaky blood brain barrier to admit the antibodies to the neuron tissue; then find out which neuron types senesce the most and the least, as well as map the brain and brains structures; see if there is a mRNA profile of senescence at brain neurons, if there is a notable mRNA difference between 1th and 99th percentile of natural brain and specific neuron type senescence at the test organism (marmoset) then find out what the genetic and epigenetic difference is, and make gene therapies and epigenetic therapies to align gene output with the favored least senescent mRNA profiles at neurons. Measure beneficial effects on cognitive durability throughout living at the marmosets.
removing senescence at the vagus nerve may be a wellness technology.
some senescence might be tissue specific, or cell specific, or with sequential scans be shown to spread to neighbor cells (one mechanism SASP); differentiate between that "diffusive senescence" and nondiffusive senescence These may work off of different mechanisms and use different genes and epigenetics. and is a spearate thing to address with longevity technologies. Light activated senolytic drugs have likely been thought of many times, but still could concentrate effect at specific organs like the brain, and notably be adjustable form 1-100 strength based on light intensity, which could be good for the brain.
map diffusive compared with tissue specific
breed a hypersenescent cell and tissue rat or marmoset based on senescence antibody body scans; do parabiosis, see if the companion rat senesces, ages, or has deleterious effects from the hypersensescent parabiosis rat, if so then find those circulating chemicals that cause the aging effect, and make receptor blocker drugs for them, as well as immunizations against them as new longevity drugs. Parabiosis of just 40 rats or marmosets finds a 5th percentile of least senescent when parbiosis-sensecence chemicalized; find out why these are resistant to senescent parabiosis. Then concentrate the genetic immmunity to senescence: breed them togehter to get 99.9th percentile of parabiosis senesence (as mapped) resistance. Those genes are then anti-senescent genes, and contribute to body youthfulness and could be longevizing as well. They could be the source of new longevity gene therapies an epigenetic therapies.
marmoset scenescne parabiosis way of finding circulatory chemicals, and 95th perctile resistant to induced senescence, breed to make resistanst to 99.9th percentile reistant to senescence
manufacturing process improvment: think of 3 to 7 (3-7) separate assembly lines making subassemblies, and then at node 1 the subassemblies are combined into a car. further the factory has eleven groups of these 3-7 separate asembly lines. It should be possible to measure the quality of the cars coming off node 1 at each of the 11 stations and find a top 10% of good car (on-specness; also other "good car" criteria to be described later). Then to find out what contributes to making a good car swap out say 2/3 of the 3-7 assembly lines machines with their twin machines from another, different, 3-7 line. Doing this programatically it should be possible to find a "best machine making parts composite of assembly lines" that makes good (90th percentile) cars say 90% of the time; similarly it might be possible to find machine making part swaps that cause "reduced quality" 10th percentile cars 90% of the time. Then there are multiple quality improvement opportunities: The tolerances of the supersmooth (highest performing) "recomposited from other lines" 3-7 line can be measured, and the tolerances and settings copied to the other 3-7 lines, and then measured to see if vehicles at those other nodes improve further; really dysfunctional 3-7 lines can be replaced with new equipment; Interestingly a drone that does 3D lidar point cloud, records machine tool vibration oscillations, does thermal imaging, records sound, takes x-rays (dental emitter detector pair only $900 at amazon) when no humans are around, and does acoustic pinging of each of the manufacturing machines; the drone could fly around hte whole factory, gathering data.
Also, it is possible to go on a "hidden quality" characteristic-seeking measurement extravaganza. So, the car is 90th percentile on-spec, but does it have any "hidden virtues" from being made by the best (3-7 peak units, gathered) machines? Is it quieter, does it sound different? if a motor is the thing at node 1, does it last longer under stress testing? Then at the best of say 11 vehicles actually produced at the best of 11 assembly lines you have a 99th percentile car. characterizing this car with a variety of sensing technologies and seeing if it is better and seems better in any way better to the consumer has value. Some data that can be gathered on the 99th percentile car are: ping acoustics, interferometry, and 3D camera/interferometry-is-it-dimensionally-true, x-ray, and other measurement forms can be used on just the highest performing of the 11 3-7 assembly lines "best of 11 cars" to find hidden variables that are increasing quality. Hidden variables can be found with statistical techniques, one at biology is GSEA, another is called non-parametric statistics where you omit starting out with a hypothesis, and classes of statistical concentration arise from the data.
Does remixing identical assembly lines to find optima work on computer chips; I think it is possible at fabs to do the resequencing and recombination of different wafer treatment machine steps to find the particular "best of" grouping from nominally identical wafer processing machines. Unlike cars, semiconductors have a big advantage in that you get a known good chip yield right away, before the wafer is cut up. Anything that raises yields would be of value, and finding optimal among identical machine lines could do that.
Aircraft and aircraft engines, and building electrical generators and electric motors could benefit from this.
Ball bearing technology: use lasers to microchannel the surface of a ball bearing or other bearing so that it coats with oil (lubricant) more avidly; noting lasers can made diffraction gratings the depth could be super eentsy, but enough to draw lubricant onto the bearing surface, and have the lubricant reside longer. One possible shape is the oil-gathering version of the water gathering trough shape \_/
Gummy statins: delicious soft Gummy candies I think have better retake-compliance than flavorless pills. If putting statins and othr heart disease preventative drugs in a soft delicious gummy form increases medication compliance 1%, then among each 100 million statin users worldwide one million more people are compliant with their statin medication use, ameliorating about 600,000 cases of heart disease. Wikipedia says, "for every 49 treated, one fewer has an episode of heart disease", so that suggests 20,000 fewer cardiac events per 100 million statin users just from changing from a pill to a gummy form. The benefits may be much larger, wikipedia says, " statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment" 60% decrease in cardiovascular events among 1 million gummy-compliant pateints is 600,000 benefit units. Statin pills are flavorless as-is, and accidental ingestion of an entire 30 days supply by a child seeking candy is likely harmless to the child. The delicious gummy strategy could also be used at the polypill, microencapsulating any ingredients that have a strong flavor like aspirin.
deuterated supplemental telomerase, or telomerase "nonfunctionalizing the molecular-machinery-combiner-alike" would block endogenous telomerase, when injected into a tumor, causing telomeres at cancer cytes to shorten "breaks cancer cell reproduction". Another possibility is an imitation telomere sequence, (new variant) that makes any cell that goes through division have "stop reading this" DNA at it, it could just be a string of stop codons; photonically activated version (activation light focuses on cancer, and systemic-wide dosing) might be possible, notably I think photonic CRISPR exists, and that or a variation on that could do it.
Internal to the body induced electricity, such as for electroporation of organs and tissues at depth to do gene therapy: it could be that an oscillating magnetic field induces electricity in tissue; magnetism only spine orgasm stimulators exist, and it seems likely they could have an induced electrical component (but, consider also diamagnetic physical squeezing); so, aim a big tuned magnet at the lungs (lung cancer treatment, COPD treatment), do electroporation of lung tissue with an AC magnetic flux and use that to let injected photoactivated CRISPR (https://www.sciencedaily.com/releases/2020/06/200617121500.htm "delivered an electric pulse to cultures of human embryonic kidney cells and bone cancer cells, which opened pores in the cell membrane and allowed the CRISPR complex with the light-activated RNA molecule to slide into the cells.") into lung cells, expose the lungs to light from outside the body, this causes cancer cells to break, and at COPD, some beneficial thing like crispr making code for growth factors like EGF, VEGF, NGF, BDNF to be produced right in the surviving COPD lung tissue to beneficially proliferate lung tissue.
Synthetic amino acid antibodies: I think it is inevitable, but I could not find mention online of making antibodies, aptamers, or other glommers with synthetic amino acids, noting that synthetic amino acids have the capacity to have different, higher, lower, and precisely tuned electronegativities and positivities, a synthetic amino acid antibody could be engineered to have much higher specificity, avidity, grip strenghth, and "immunoflagging" ability than a natural 20 amino acid antibody version of the antibody. at things like colorimetric antibody saliva tests the range of things that can be tested would go up. Genetic algorithms could be used to design the optimal synthetic amino acid antibodies. These synthetic amino acid antibodies could make for better vaccines, anti-cancer treatments, and body tissue and organ localization of drugs attached to the new antibody, Aha, it looks like they are doing it: https://research.monash.edu/en/publications/engineering-the-orientation-density-and-flexibility-of-single-dom "we used an anti-EGFR single-domain antibody (sdAb or nanobody) to target fluorescent nanocrystals (Qdots) to epidermal growth factor receptor (EGFR)-positive cells. The sdAbs were expressed with a synthetic amino acid (azPhe), enabling site-specific conjugation to Qdots in an improved orientation"
Greenshift: Greenshift is one way to create side channels or side areas to the lightcone that you can do stuff with, like distant sensing or starting isolated MWI universes, or communicating faster than photons. Cerenkov radiation is where light is emitted when neutrinos exceed the speed of light in a refractive index media, glowing blue water at nuclear reactors is one example. So neutrinos, travelling through a thing with a refractive index, can go faster than light, and, if you have good neutrino detectors, optics and emitters you can do neutrino circuits (like photon circuits) with them faster than light at say a planetary atmosphere or through a Jupiter like planet. Consider an interstellar, even pan galactic community that communicates with neutrinos, as long as the medium has a refractive index then the neutrinos outpace light, and the community can communicate faster than light. One thing about neutrinos in a refractive index medium going faster than light is when a neutrino-photon pair is created, the neutrino, in a medium, zooms outside of the photons lightcone, insulating the neutrino's uses from the lightcone of the photon; so, this is a side space outside the lightcone that could be used to do things like computation faster than light (again, at a refractive medium), and the ability to do things like generate "report back" of computations (and non turing automata); neutrinos or photons can communicate the computed answers the greenshift volume produces. Of interest to transhumanists is putting backups of sentience outside the lightcone of daily living with greenshift. Notably, if the neutrino detector at a greenshift volume then makes a new photon at the greenshift volume in response to a greenshifted neutrino then that photon produces MWI universes outside the lightcone (photon cone) of the source. So Greenshift makes a side volume to do things with. Now, can you do greenshift with photons instead of neutrinos, along with neutrinos to do greenshift you can use diferent colors of photons where some are, and some are not admissible to the bandgap layer "forbidden zone" of a bulk material (like a big chunk of doped diamond); photons that can spend all their time visiting/hopping through bandgap/forbidden zone can greenshift relative to their photon peers of the other color who physically have to take a different path (Note the 90 degree turn of microwaves at a forbidden zone wax prism youtube video; other photons besides microwaves can likely make compelled 90 degree turns like in the wax prism video). The photons that can travese the bandgap material/forbidden zone material (without making a 90 degree turn) can interact with things and start their own lightcones/timelines independent and completely separate from the timeline/light cone of the other color, this creates separate lightcones of influence for the two different color photons even though they can be emitted simultaneously or at minute delay from each other. AI sidespace spplications exist like isolating running programs from each other in different lightcones. A Transhumanism application is different new to me kind of parallel time that is variously rejoinable after an bunch of greenshifted events (time away on the side), permanently dividable, or even could provide an energy pumping side greenshifted volume at pumping a laser.
As previously written at greenshift, I think, you could detect things (scanning) in greenshifted side-lightcone mode before a photon could ever reach them, and send the information back to the neutrino/photon launch point. Supporting greenshift technology development is a 15kg neutrino detector https://physicstoday.scitation.org/do/10.1063/PT.6.1.20170817b/full/ that uses crystals ("the detector, which is made of a transparent, scintillating crystal of sodium-doped cesium iodide.") to detect neutrinos; arraying those crystals as volume would cause higher resolution
Greenshift can occur at a glancing to 90 degree angle to stay out of the lightcone of the photon source, noting the nabisco logo |||-O basically greenshift can use a side area to make the nabisco antenna, and any functions it may have, like automata including turing automata, and analog computing, branches of the nabisco antenna can be aimed back at the lightcone, or aimed even further away from the lightcone to variously share data and computation or sequester it. greenshifting neutrinos or photons to store or separate energy, the charge coupled device (CCD) could be at a greenshift area and heighten energy (also make/pump lasers) outside the lightcone
Quantum entangle photon and neutrino; neutrino greenshifts ahead and to the side, measures things, and the quantum linked photon then tells the technologist/user what the things are long before a photon could reach them, similar to the Quantum Camera at New Scientist magazine.
gravitation makes transhuman Jupiter brain even more enriched: computer in the middle of a gravitational object runs slower, computers at perimeter run faster; applications to the central computer asking questions, "factor this" and the speedy ones figuring it out, replace the central computer with a sentience and the perimeter computers with nonsentient simulations of that sentience and the central sentience can run billions of copies of itself to find the optimal thing to do/think next; adantage to central sentience of being at gravity gradualism is longevity based on fewer atomic motions per millenium
quantum linked photons (entangled photons) exist as does the New Scientist Quantum Camera, use quantum entangled (linked) X-rays to do brain scans; also spectroscopy of neurons and neurotransmitters from outside the head/brain could be used for brain scanning
a new kind of brain and tissue scanner; it is possible that just as semiconductors have a bandgap/forbidden zone it is possible tissue or individual proteins have a bandgap forbidden zone; if so then part of the brain might be at that bandgap, and part of the brain might be outside that bandgap, and measuring radiations could be compelled to hop over those areas that are bandgap/forbidden zone causing greater depth before absorption at 1 mm-UV photonic brain scanning. that makes it so that greater tissue depth of photonic scan is possible, possibly with 1 mm-UV range photons; utilizing the quantum camera technology described at New Scientist magazine simultaneous with the brainscan/neuron type bandgap/forbidden zone then images tissues and brain at depth with photons in a new (to me) way. One thing supporting this is the 90 degree photon turn from wax prisms and microwaves (another person's youtube video). if microwave RF can make 90 degree turns from evanescent waves at a forbidden zone, then it is possible that heightened resolution non-diffuse bandgap/forbidden zone photonic imaging of the brain is possible. I think water has a bandgap, so photons *or endo- fluroescence* unable to be at water's bandgap would image nonwater components of the brain only.
More intense than catnip, chlorocatnip or fluorocatnip: Halogenation often makes chemicals attach to receptors 10,100, 1000 times more powerfully, so halogenate catnip. As a .5b idea this could be blenderize catnip with a mixture of polar and nonpolar solvent (oil, water), let the mixture separate. At the nonpolar solvent version put some bleachwater in with the catnip-enriched and blenderize 2-3 minutes, then let settle out or centrifuge. See if the cat likes it better than catnip. similar procedure for the water fraction of blenderized catnip, but add sodium thiosulphate to neutralize excess chlorine at the water reacted with bleach version, see if the cat likes it. Intriguingly, if the cat likes both, do the water and nonpolar solvent versions elicit different pleasurable/excited behavior from the cat. This based on something online I read about how to halogenate Vitamin E. similarly halogenated published human pheremones could be orders of magnitude more potent and have stronger effects, beneficial as relationship and sex technology applications. Halogenated moth pheremones work bettr on moths than unmodified pheremones
CT scans and x-rays that are less risky, and possibly beneficially hormetic: Radiation hormesis is published, and they could test x-rays from soft to hard x-rays in 1% frequency intervals (48 mice, 100 different overalapped x-ray treatments; matrix experiment math) to find the particular x-ray frequencies that causes the least cancer and most hormesis. Once they find those least deleterious/most hormetic x-rays they can use them for human x-ray imaging equipment like CT scan and radiography. The advantage of finding a kind of x-rays that causes 1/2-1/4 as much cancer as previous medical imaging is that increased mass screening is more numerically supported. It is even possible that a hormetic dose of radiation, and actual benefit, can be given and still have sufficient detectability to make high resolution images; that would make CCT scans actually good for wellness.
A skin probiotic that is engineered to make human attraction and possible sexual interest pheremones could be a one-treatment +2 charisma body shampoo event.
Bundle a feline saliva toxoplasmosis test with pregnancy tests to let people know immediately if their cat's infection is a risk to their baby's health, especially mental health.
.5b startlingly peculiar way of oxygenating aquariums: have immersed container do DC electrolysis of water to hydrogen and oxygen, the gases bubble up and out of the container, oxygenating the water, notably without pump noise; what happens to the hydrogen? uh-oh, perhaps a fan on the upper surface of the aquarium blows on it and mixes it away to harmless concentrations
I favor making humans impervious to weather: wikipedia says, "Hibernating Arctic ground squirrels may exhibit abdominal temperatures as low as −2.9 °C (26.8 °F), maintaining sub-zero abdominal temperatures for more than three weeks at a time, although the temperatures at the head and neck remain at 0 °C (32 °F) or above." So there is a sucessful mammalian genetics of living at below 0 celsius; finding out how that works them making it a component part of humans and the humane germline genome assists in beneficially making humans impervious to weather.
do hibernating Arctic ground scquirrels make antifreeze chemicals at their cells? If they do thsoe could be longevity and wellness chemicals, and anti-frostbite chemicals to make at human beings, a supporting technology in making humans impervious to weather. wikipedia suggests, "The best theory as to why the squirrel's blood doesn't freeze is that the animal is able to cleanse their bodies of Ice nucleators which are necessary for the development of ice crystals." That seems suggestive that the liver or kidneys could filter out or enzymatically neutralize nucleation site chemicals at the circulatory system. Wikipedia also notes other arctic mammals (a source of impervious to weather genes), "animals, along with their close relatives the marmots[9] and the un-related little brown bat, that hibernate."
Thinking Dave Pearce' Hedonistic Imperative and Abolitionist Manifesto, the mass genetic engineering of all mammals to have the genes that permit arctic ground squirrels to have body temperatures below 0 celsius could remove winter as an existential risk to all animal (mammal) life; winter would cease to cause mammals to be other than alive.
Longevity technology: humans at 1th percentile of family longvity may have deleterious epigenetics; copy their epigenetics to mice and marmosets and see if that does the opposite of increasing lifespan; if it does winnow out which specific epigenetics locations (genes) cause the deleterious effect. Then try the opposite epigentic activity at thsoe genes, amplify if repressed (acetylate and demethylate) or decrease if amplified. Tests on age batched goups of marmosets could then see if the new epigenetics caused greater longevity or also wellness. If they do they can become one dose human epigenetic therapies that cause longevization.
Possibly at the paper notes: copy epigentics of bowhead whales to age batched marmosets to see if they live longer, if they do then those are epigenetics of greater longevity and can be tested on age batched groups of humans to develop a one dose lifespan increasing drug.
I think I may have misunderstood, but mice bred to overexpress GDF-11 lived 47% longer, at laboratory mammals and then humans the epigenetics of the genes that code GDF-11 could be switched to high production (acetylated) and then age batched groups of human volunteers used to test if it was longevizing at humans.
I think at the imaged paper notes I wrote about how a researcher played "rain forest sounds" to mice duing the day and they lived 17% longer; they could play age batched marmosets "rain forest sounds" to see if they live longer. If they do, mRNA (gene expression) profiling could find out the difference between marmosets that listen to longevizing music and those that do not; having found those genes that modulate their action to cause greater longevity from music RNA drugs could be tested to upregulate and downregulate those longevity genes, only moreso. There is also an opportunity besides developing drugs to have computers and genetic algorithms that duplicate the marmoset's gene product response to music at humans, that is music that causes the longer lived marmosets gene expression profile is duplicated at humans. That could be more effective than 17% at longevizing humans and sound enjoyable.
Genetics and epigenetics of the sense of beauty that can be made into enhanced beauty appreciation technologies and genetic drugs:mz twin studies where there is disparate amounts of seeing beauty in a sample of computer images could show one MZ twin seeing beauty twice as often, possibly traceable to epigentics, possibly to other things; a particular style (focus) of beauty appreciation may be found on the internet from surveying a large population, to find disparate people that happen to like the same top 4-7 portraits, then seek shared genetics and epigenetics; the genetics and epigenetics of appreciating the beauty of the human form, especially the human female form, as well as responsiveness amplitude to pleasant beautiful facial expressions like duchenne smile and beautiful (science word) microexpressions are developable; childrens sense of beauty compared with teen and adult sense of beauty; genetics of human hyperobservers of facial expression, but made all upside from only hyperobserving beauty; mRNA of MDMA use could be associated with beauty appreciation genes and epigenetics; gentics of depth perception, does more than 99th percentile depth perception cause enhanced 3Dness at things like faces or womanly curves; what is the optimal, normal range, percentile of depth perception to see more beauty, such as at the curves and face of a woman? If this is significant it can be made into a germline gene therapy to optmize beauty from depth perception;
hox and other developmental genes for the form of orbito-frontal cortex of brain could heighten beauty sensation, "Prior to scanning, each subject viewed a large number of paintings and classified them into beautiful, neutral,", "They then viewed the same paintings in the scanner. The results show that the perception of different categories of paintings are associated with distinct and specialized visual areas of the brain, that the orbito-frontal cortex is differentially engaged during the perception of beautiful" and " Because the activities in the anterior cingulate and in the parietal cortex only became manifest in the contrast beautiful versus neutral, of greatest interest for our purposes is the activity in the orbito-frontal cortex and the motor cortex." https://journals.physiology.org/doi/full/10.1152/jn.00696.2003 so genetics and epigentics of orbito-frontal cortex could be beauty sensing technology sources, such as germline gene therapy to appreciate beauty more, and see more beauty.
recreational pharmaceutical "goggles" that cause others to appear more attractive, how do they work at the brain structure and neurotransmitter level? if/when they find out, then it is beneficial to make beauty "goggles" all the time be made part of the human germline (make RNA drugs) without intoxication
https://www.veryengineering.com/beauty-is-subjective-the-algorithm-says-it/
Beneficial new germline human genetics and epigentics of thinking before acting: Motor cortex fMRI activates when social norms are challenged (published), so a thing that decreases motor cortex activation on experiencing challenges to social norms could favor something else over immediate physical action, that could be a moment of thought.
Improved grain drying at agribusiness/farming: use IR lasers to dry grain; approaches 100% efficiency as the warmth from the laser diode just contributes to the grain dryers overall temperature; 5 watt IR laser is only $2-3 at alibaba so 100,000 watts of grain drying is near just $50,000 in laser diodes; advantages include computer controlled precision of amount of grain dryness Also, noting "flashlight fingers" grain drying could occur at inch or more depth with laser diodes. This brings up a big one, making cement might be 2-3% of global greenhouse gas emissions; could ecologically sourced electricity power IR lasers to make cement? The temperatures are achievable, and I imagine a thing like a conveyor belt of preheat cement could work. Other laser advantages in making cement are comminution and zap-to-microparticulate (like dental lasers); zap to microparticulate could optimize cement grain size for added value and better engineering characteristics.
Longevity technology: other spermidines, like trans spermidine, multinflection point cis & trans together Could make C-shaped molecule, putting in some C=C (Desaturating), ethynyl groups and halogenatation are likely described at paper notes, different "alkane" C7/C9 lengths; screen at yeast or c elegans; Spermidine causes lab organisms to live 10% longer, but is a highly produced chemical at 90% greater longevity LKM-512 bacteria so new even more longevizing versions of spermdine would be longevity drugs.
Acoustic waves improve crystallinity technologies: acoustic waves effects the annealing of steels, 1981ad:" The influence of 20kHz ultrasonic energy on metallurg ical properties of cold rolled sheet steel specimens during anne- aling was investigated. Acoustic energy caused an acceleration
in grain growth rate. Annealing texture was also modified by ul trasound as well as the grain growth was enhanced. As a result of
these effects, the ductility of the sheet steel for press forming was increased appreciably, and the drawability hence much improv ed. Efficiency of over-aging treatment in a continuous annealing
process of sheet steel was increased appreciably, and the drawability hence much improv ed. Efficiency of over-aging treatment in a continuous annealing
process of sheet steel was nearly doubled by ultrasonic irradiat ion during over-aging."https://hal.archives-ouvertes.fr/jpa-00221054/document ; have they tried solitons yet, and could they use spatialization of the acoustic beam, or beat frequencies at grain sizes (physically treat each little grain as a reonator, and tune the acoustic wavelength to that size <=> grain chunk, compression waves compared (geology like P, S waves) with longitudinal waves; at a big disk of steel or other material they could do not just one frequency combining 2 or three frequecy Chladni tests with chladni patterns and then test for increase hardness with drop-gouge tests at 3 mm intervals on the disk to find out if any of the chladni patterns' concetration areas caused diferent steel charateristics at that local test area of the chladni "doily". Polymer annealing with acoustic waves: this Chladni testing (mass characterization) of acoustic waves during annealing could also work on "annealing" crystalline polymers, that is plastic, and it is easy to imagine an acoustic beam pointing at a 3D printer nozzle to make the printed polymer or metal have even better characteristics and a wider range of characteristics. with acoustic grain size effects it is possible aluminum and polymer beverage containers could be made from less material if their polymer or metal has different grain size, benefitting the environment. Aircraft aluminum could benefit from acoustic effects on grain size during manufacture, producing stronger aluminum, so less is utilized, so the airplane weighs less, saving fuel. it is published that acoustic annealing can also increase hardness, "It was found that the ultrasonic treated samples of 0.07% carbon hypo‐eutectoid steel had finer grain size and greater hardness than the reference samples which had undergone the same heat‐treating cycle but with no ultrasonic treatment. When either the intensity or the frequency of the ultrasonic energy was increased, the grain size was further decreased."; increased hardness from acoustic treatment of ball bearings and other bearings, the raw bearing material could be made harder with acoustic treatment during metal manufacture. It is even possible that reheating and reannealing of a completed ball bearing or bearing with strong acoustic hardening could make ball bearings better. They could also test the effect of acoustic annealing on silicon nitride bearing manufacture. noting the idea of grain size generally, acoustics during manufacture or installation could effect the hardness of poured concrete, including sidewalks and roads and premanufactured things like bridge components, causing greater durability or also less concrete to be utilized.
they could see if acoustically stimulating particular crystallinity of grown semicondocture boules that IC wafers are made from can increase some beneficial aspect of wafer crystallinity, perhaps providing a choice of different crystal forms at a wafer-boule (like gamma, alpha, beta crystals); it is even possible, although wiggling a wafer during photoresist exposureis nonoptimal, doing the acoustic stimulation wiggling of the IC under construction, only at the material deposition part of the sequence, but not at the photolithography exposure could cause things like crystallinity (and selectable gamma, apha beta crystal forms), rather than amorphousness, of transistor layers, improving transistor performance at integrated circuits, and perhaps making things like laser diodedes better with custom crystallinity (gamma alpha beta crystal forms) and new devices possible.
Batteries electrode materials could be acoustically enhanced at time of manufacture to have optimum crystalinity (and gamma alpha beta form of crystals) or amorphousness, possibly making batteries have more recharge cycles and less drop off in voltage produced
Drones that paint could beam acoustics at the wet painted surface to effect nucleation/attachment sites of the paint to the underlayer increasing adherence. Also of course there is the way acoustics could pressure-wiggle paint into its substrate.
laying down different crystallinity or also grain size in layers: lets say 40 Khz causes beta crystallinity, and 80Khz causes gamma crystallinity; at layered device it is posible to purposefully alternate the acoustic crystalinity and grain size making frequency to make a layered structure, layered structures could lead to better devices and even new devices such as a depthy x-ray or medical radiography detector or a depthy neutrino detector, or a depthy hyperspectral imaging camera chip; also I'm ignorant, but phonons and plasmonics do things at boundaries, so making acoustically enhanced layers, makes stacked phonon/plasmonic devices to do more of what phonons and plasmonics at crystals, like ICs do well.
20Khz causes ductility; could antinodal waves (active sound cancellation) to any acoustic waves steel naturally makes when being cooled or heated have an effect on toughness as the steel cools quieter;
Scientists often crystallize proteins for characterization; an acoustic emitter as part of the protein crystallization apparatus could improve the crystallizability of proteins, benefitting research.
weather adjusting acoustic emitters at flying drones: like the way metallurgical acoustic stimulation effects grain size, acoustics could favor the creation of nucleation sites around which droplets gather to make rain at night, or if a sunny day is preferred, acoustics could disrupt the natural creation of nucleation sites that make rain) Applications to power plants as keeping steam (like dry steam) from nucleating to water could make it last longer for greater energy extraction of the heated water, making the steam less condensing.
utilizing acoustic effect on grain size and cystallinity to have anti-corrosion effects at at treated surface/bulk material of a variety of alloys; acoustics at manufacture could make industrail reaction vessels metal alloys have less oxidizability (from optimizing beta gamma alpha crystalline form, and even one layer only oxidation like aluminum), which is beneficial for making chemical industry reactors and petroleum industry physical plant more affordable with longer vessel longevity.
Acoustic tranmission through gas (like air, or a higher gas pressurized system) goes up with the dnesity/concnetration of the gas; numerous acoustically modified grain size and crystallinity technologies could be enhanced by manufacturing them at a compressed gas or even liquid environment which transmits sound (acoustic waves) more effectively. the internet describes the acoustic horn, which causes +18 dB of greater loudness, somehow, from an acoustic source; if the acoustic horn is used at the acoustic treament to change grain size technologies then less energy is used to produce the delivered acoustic energy and preferred grain size effect, improving the energy efficiency of acoustic treatment; there could be a not free-space airgap or fluid gap acoustic horn, but a "bolt on" horn that directly acoustically stimulates a piece or material or machine to be acoustically enhanced. Just as genetic algorithms can make an antenna 300-400% more efficient it is possible genetic algorithms applied to acoustic horns could more than double their efficiency.
minimax curves (saddle-like) have been used to model phenomena, including social stability phenomena and nuclear waepons, and the thing is, how to you keep the central movable stably at the center. This link https://sciencedemonstrations.fas.harvard.edu/presentations/rotating-saddle shows a rotating saddle causes minimax saddle curve to support a dynamic central stability rather than roll-off; applications to product yield at chemistry, and even aerodynamics, or drone propellor blades, or anyplace a minimax curve *or other roll-off curve* is measured or designed to occur. it is possible that a wide range of sadle curves and differnt than saddle curves could be stabilized with rotation; similarly if you want somethings to react (hints of a undulating bumps and parabolas at a chemistry energy reaction diagrma) you could do the opposite of roation to morre rapidly destabilize an item on a saddle curve, or toehr curve, one possibility is laser tweezers cooling the atoms, removing any spinny angular momentum they may have; another possibility is mass-throughput computer observing the atoms to be particles rather than waves at chemical reactions, possibly making their physics that of a ball sitting on a saddle, with that technology causing quick roll-off (higher reactivity, faster reaction), Also there are math equations that turn one thing into another, a logarithmic s curve graph could be restated as to what curve comlements/antinodes/roating saddlizes it, would make the near linear region (the / part) longer or shorter, which has applications to chemistry and petroleum refining, as well as purposefully addressing any s-curve phenomena the technologist wanted to make anew machine around. Another curve susceptible to rotation stability effects: The cure for a parabola (rather than a saddle minimax curve) could be repetitive translation or rotation.
preservative ray: keeps atoms unreacted from adding a rotation (anti-saddle run off) component to the atoms way of being, perhaps something direct like circularly polarized EM/RF could do this; adding "no-runoff" rotation to a laser based atom cooler/freezer could cause greater efectiveness, which could have applications at quantum computers.
a laser stimulated at depth dielectric. like on an IC might have an addressible "roll off shape" math compnent, so the laser would rotate or antirotate (*; other shapes including :::) the illuminated area and make the dielectric either more or less resistant to electron transport from reducing roll-off; a little laser diode inside chips could effect all the dialectrics on the chip by illuminating them, making them even more insulative from preventing roll-off, supporting reducing feature size and improving statistical resolution of what is and isn't a bit.
https://sciencedemonstrations.fas.harvard.edu/demonstrations/oscillations-and-waves?page=3
Observing battery chemistry to be particle (or wave); does observing a battery with a computer to make its internal electron state and electrolyte atom state to be a particle then cause differences in chemical reactivity? this could cause different engineered effects throughout different parts of the the battery; and, novelly, greater molecular modelling efficacy and efficiency from a simpler (particle) represenation of the observed-into-particle battery (or chemical process industry) chemistry.
lissatricity, previously described could combine two (or greater) electron orbital simultaneously mobile materials like silver and polymers with a computer that observes it (the electrons or their lisatricity composites) to being particle or wave; One or the other migth ave different responses to resistors and capacitors, also as to saddle curve non runoff rotation effects lissjous figures from a waveform or two can make roating circles, roating circles could be used, like spinning a saddle curve to make saddle-stability or instability at flowing electricity/lissatricity; lissatricity migtht benefit from an observer computer of new kind of electronic component that always observes it into wave (amongst particle and wave options), causing the lissatricity to be at most likely to add (superimpose) waveforms way of being.
Similarly, light at optical fibers could be observed into either particle or wave identity along the data path, or from above, or with a optical cladding observer fiber sheath, possibly particle light increasing the TIR total internal reflectance of the fiber (farther distances between repeaters), or making bits more discete somehow with particle light. the observed into being a wave light at photonic computers and internet fiber optics could be used for optical computing because the muliplicty of overlapping states and characteristics that are predetection are favored by wave photons.
Brain amplification technology: a photonic circlet is worn on the head, it has a computer that emits and collects photons, it can be switchable to all particle resolution, that is determintion, of brain observations or all wave identity, as well as thousands of steps of ratio between the two. Scientists and developers then study if particle identity brain chemistry observation causes different behavior and mood and sentinence form than wave identity, from the circlet's observation alone, and they could study making (observing) the nucleus accumbens as a wave, and the neocortex as particle as well as the other way, to see which version causes thinking to be the most fun and the most productive, so this is brain amplification technology.
at a medical scanner a co-scan that causes all the brain chemicals to be observed into particle or wave identity could effect and increase resolution of the main scan
particle or wave preobserved forms could beneficially effect the efficiency of biological research, perhasp particle-observed CRISPR and PCR works better, or at testing drugs on tissue cultures, wave causes more unintended effects aperture gap sequence observerness, two or three layers, the contrast betwen the edges of particle and wave observedness are particularly detectable with imaging, like medical imaging
MWI (Many world interpretation of physics) language, does the number of MWI universes go up if you simply say, "there are more diferent things to do this afternoon than there are electrons in the universe, to start a list, hug your physiological child, 2) take MDMA, 3) study mathematics, 4) have sex utilizing sex drugs for an enhanced sexual experience, and so on. then you would say, "lets pick one to do, and then do it"
getting pregnant with genetically enhanced sperm: cervical annulus like nuvaring diffuses sperm out of it for 94 days; internal egg vibrator with kit (24 cent vibrator at alibaba) or sexual pleasure vibrator has special frequency and acoustic spreading aperture that cause sperm and spermatids to be massaged up the fallopian tubes, the vibrator's travelling waves pushing the sperm liquid up the tubes; a fallopian tube dilating chamical is also included to make the fallopain tubes their widest; if fallopian tubes have peristalsis the chemical (found via mRNA profiling) changes the direction of paristalisis to pull material like sperm up and towards the egg. the gentically engineered sperm could be of two kinds, one with a tail and motile (an area of active research at sperm tissue culture (it works in mice), the other not motile, which I think is called a spermatid and is like just the head of the sperm, spermatids and sperm are transported to the egg via vibrator vibration in a dilated fallopain tube; the sperm and spermid forms both would have glomming apatmers or antibodies on their surface, made from dipping them in a chemical, which physically attach them to the egg if they collide with it; the tailless spermatids as a result of their size and mass have a particular resonant frequncy of motion at mucousy tissue, and the egg, being very different sized would have a different standing or moving wave resonance, the effect of playing both spermatic and egg frequencies at the same time with the vaginal vibrator or even vibrating cervical annulus is to repeatedly collide tailless spermatid and egg, which functions just as well as if the sperm has swum into the egg with some force, fetilizing the egg with just a spermatid. (2021 state of the art). notably the cervical annulus could do the vibration if batteries are efficient; and it could wireslessly recharge from an electromagnetic charger with small mattress towel of circular form.
Do spermatids live longer than tailed sperm, if so there is actually a 94 days of preservatives and diffusion cervical annulus basis to use spermatids with fertilize the egg with a spermatid technology.
Another possibility for having a swimming sperm deliver a separate spermatid package is to use lipid rafts and adherins to glue a gentically engineered and enhanced genome tailless fertilization-capable spermatid (human tailless spermatids can fertilize when injected into an egg; 2021 AD technology) to a swimming sperm that has been zapped with a laser to have a an inactive payload and be sterile, the sperm with two heads then seeks out and swims to the egg and fertilizes it. a million channel microfluidic device that glues sperm together could generate 60 million two headed sperm in 120 seconds (maybe), 60 million is a typical ejaculate sperm amount; the cervical annulus could release a million genetically enhanced sperm a day for 94 days. Another possibility for gluing spermatids to sperm with maximum affordability, is just to react them together in a culture medium with adherins and lipid rafts, sort with colloid gradient or centrifuge to concentrate the two headed sperm mass layer, then use 10 million cytes per second/minute flow cytometry to screen and sort two headed sperm at say 11% viability, producing a million swimming two headed sperm a second/minute
GHK, other beauty peptides iontophoretically reach 1.5 cm depth with paint-on electrophoretic face treatment (mask); beauty peptides are published as working to rejuvenate skin, and GHK actually comes from a peptide that rejuvenates livers. a two or three layer liquid beauty masque could be applied to the face once a week or once amonth and use the electrodifferences between the layers to iontophoretically drive the beauty peptide up to 1.5 cm deep in 30 minutes; the botton layer of the paint on (or applique) masque has the beauty pepetides, the middle layer is insulator and iontophoretic fluid, the top layer is laser-photovoltaic "mica flakes" that make voltage from an IR/UV emitter that illuminates the face brightly.
polarized light effect of making a multicolor form that changes when physically compressed if levered, seen at clear plastic things at science museums; could the same effect be used at x-rays that do CT scans and radiograpy to provide additional information at the scan; the two near each other x ray frequencies could form an interference pattern that has peaks and troughs of heightned resolution; an x-ray detector that detects x-ray polarization could make this work; the internet says there is charge coupled device that will detect x-ray polarization; metal bearing liquid crystals at liquid crystal shutters might also detect poalrized x-rays or make them as a filter, tehy could be elctrically actuatable for sanning purposes.
halogenated ethynylized laundry detergent enzymes could be 10,100,1000 times more potent per milligram; similarly could halogenated or ethynylized quats be much more powerful as disinfectants
compressed generator and motor wire and compressed magnetic materials: "Iron atoms are arranged in a body-centered cubic pattern (BCC) up to 1180 K. Above this temperature it makes a phase transition to a face-centered cubic lattice (FCC). The transition from BCC to FCC results in an 8 to 9% increase in density, causing the iron sample to shrink in size as it is heated above the transition temperature." other metals and alloys may also have a volumentric crystalline form transition when heated or built at cryogenic temperatures; light and superdense cobalt at catlysts could be possible, light and heavy NIB magnets, light and heavy aluminum or Cu wire at generators and motors. packing 9% more atoms into a conductor of the same size suggests that littler gauge wire could be used at generators and motors, but without increasing resistance; at generators the largest number of turns of wire next to the magnet or other coil seems likely to have the higher magnetic flux, and higher magnetic flux concentration at a generator I think increases its strength of field, thus increases its maximum energy (electricity) output per generator rotation. So, what is the densest Cu and Al crystal form for use in wires? "puffy lightweight platinum" metal crystals would take up more surface area per milligram, providing 9% cheaper catalytic converters. "puffy gold" could be used at computer chip wiring and cover 9% more area per gram. puffy versions of the unusual metals in phones could make phone materials 9% cheaper; at silica (glass) 9% puffier or 9% harder might be possible if crystalline silica is used, applications to strong building windows, even cheaper drywall, and light elegant disposable glass beverage containers, also, the preparation of cement could have a choice of crystallinty at the cement crystal materials, puffy cement might be 9% more affordable, using less energy to make, and relatively energy saving to make while 9% harder cement would have structural materials advantages. I think I read some gas and aircraft turbines use single crystal turbine parts to maximize strength. It is possible a BCC/FCC like 9% densification increase fromm shrinkage is posible at singe cystal (jet engine) turbine parts making them perhaps stronger and more immune to heating. https://sciencedemonstrations.fas.harvard.edu/presentations/bcc-fcc
green ceramicsand adjustable shrink/grow with crystalline difference
warping, math:curl, bifurcation and grain and overloading of planck interavals relatavistic compression wave pqrs ane calculus jerk
is planck volume a cube or some other space flling solid
methane and hydrocarbon technology: wikipedia says, "The intersection of four balls of radius s centered at the vertices of a regular tetrahedron with side length s is called the Reuleaux tetrahedron, but its surface is not a surface of constant width.[70] It can, however, be made into a surface of constant width, called Meissner's tetrahedron, by replacing three of its edge arcs by curved surfaces, the surfaces of rotation of a circular arc. Alternatively, the surface of revolution of a Reuleaux triangle through one of its symmetry axes forms a surface of constant width, with minimum volume among all known surfaces of revolution of given constant width" that suggests where the 5 atoms of CH4 meet at the center there is a kind of geometric orbital overlap shape; anything that modifies that shape, including things that effect the external HOMO shape of methane to make the interior carbon have pointy parts makes the CH4 more reactive from the pointy parts being more likely to react with other chemicals. MRI uses big magnetic fields, and is also published as causing actual chemical changes at the scanned tissue, so big magnets oscillating or unvarying could effect the center region of methane making it more reactive. a cheaper approach to big magnets is to have the big magnet like an annulus around a tube, and the tube contains methane and air/oxygen. This has applications to cool combustion of methane, catalytic generation of higher value hydrocarbons from methane but at lower process temperatures, and fuel cells, Also, a new kind of catalyst that comes near methane and changes the central multisphere overlap to be pointier could be a technology; genetic algorithms at physics and chemistry software could possibly find it. Tuned solitons, tuned to be absorbed at at particular molecule could distort the sphereical overlap central area; the solitons could be EM/RF like the range from microwave to x-ray, or even magnetic solitons and when beamed at a hydrocarbon would cause it to release energy faster from dissasembly (susceptibility to oxygen); it is even possible common chemicals at coal could have a soliton/big magnet/RF absorption frequency, making a beam or field that causes cheap coal to have better energy producing characteristics (faster, higher amplitude oxidation), possibly also even resulting in less pollution.
gombach molecular forms could be unusually stable
the water knife like the coanda effect Exair air knife could be produced at tiny (3 cm) size at a boat hull crawling cleaner robot, slicing deep at fouling on the hull of a ship to remove the gunk. recharges from boat electricity, similar versions could roam around on the surface of commercial real estate keeping it clean, and regulalry refilling the water tank. Coanda effect water knife, or air and water combo knife is likely better at cleaning than pressure washing, so perhaps they could just find all the pressure washing applications and change them to automated air knife cleaning by drones. air knives are 6 decibels quieter than leaf blowers so perhaps there is a kind of pump that can power a coanda effect leaf blower for quieter leaf blowing. antinodal audio broadcast speakers on leaf blowers could also make them perceptibly quuieter at "lobes" of sound around the leafblower, notably doing active noise cancellation where the users ears are. nifty software could spot all the people near the leafblower, such as user and passersby, on live video; and then adjust the supplemental antinodal sound lobes to be quietest where the video/software saw the people. Same thing for dentist drills and power tools and construction equipment (and cars and scooters). an office desktop version could antinodal cancel the sound of the building's HVAC, if any, as well as at in-window air conditioners and fridges.
Flibanserin is a women's 2021AD sex avidity increasing drug, enthynylizing it oculd make it 10 times higher dose potency, and attaching a peptide to it so that it passes the blood brain barrier could make it 2-10 times more dose active, resulting in 20-100 times greater potency, at a snortable or sublingual dose; they could give it to 300 people, and people at the 95th percentile or higher in increase of voluntary sexual activity (likely near doubled sexual activity or higher) and their genetics compared to minimal responders to find epigenetics, and epigenome modfying drugs of greater voluntary sexual activity based on regulating those genes to be like the high flibanserin responders.
The free base of flibanserin may be possible to make, and could be snorted as gel-microcrystals to provide another 2-4 times activity factor.
If the dose of the enthylized blood brain barrier passing peptide or also liposomal version is 2mg/24 hours then 1.3 grams at a needless controlled release injection (like airjection of collagen) would treat a person for 2 years with one office visit.
Longevity technology: some epigenetics shared at long lived plants (Bristlecone pine, King's Holly) genes may also be shared between plants and humans, noting that people share hmologous 60% genes with some banana plants, they could also share epigenetics as well; compare the epigentics of bristlecone pine (4k year lifespan thus far) with a century longevity pine, see which epigentics, at the group of genes shared with humans, are different at the 4K year thus far lifespan bristlecone pine. Then with that list of epigentic differences drug mice to have the epigenetic difference at bristlecone pines have to see if it causes greater longevity at the mice. If it does test it on age-batched groups of marmosets, if that works make it a human epigenetic drug as well as a gene therapy. this could also be done with the epigentics of clonal entire-hillside trees that have published 49+K year longevity
It is IT pattern beneficial that baby garments, if the babies are wearing garments, be all white. optional words in light sky blue on the white garments could say things like, girl, boy, hug me, and others)
noting the peltier effect has to do with electrons and holes, could it be possible to make a cooling device based on proton counduction? Protons instead of electrons would move to do the cooling; The internet says there are proton semiconductors and a proton conductor transistor.
New kind of computer with much faster computer clock rates: laser triggered microprocessors; pv, attosecond lasers, the pulsed photons potentiate or nudge semiconductors into activity; causes 10^18 semiconductor activations and functional CPU clock speed from laser triggering interval; what if you had a CPU and instead of a clock cycle it was stimulated photovoltaically externally 10^18 (or higher) times per second, each stimulation advancing the clock, like a substitute for a square wave at a conductor (2021AD) CPU; the photon interval would determine the clock speed, and the pulsed photons use photovoltaic effect to advance the CPU's calculation and clock. Further, a group of optical templates could do things like make spatially disparate charges and even project NAND gates onto a new kind of fine-grain computational substrate, leading to on-the-way microprocessor form complete changeablity at one chip. The thing is, how do you make the optical projecetion templates detail rich and sized right to configure the semiconductor; UV is a start, as might be "viewmaster" CPU designs cassette; if you are willing to go big, and use a shrinkifyng lens then reorientable quantum dots, like, or also, a liquid crystal shutter, with like a picomole of liquid crystal per well could cause a particular CPU circuit ordering; At 300 FPS that makes the ability to completely reconfigure the physical trace pathways of the type of computational device (CPU, GPU, other) 300 times per second and then run the computations at 10^18 or higher external photon pulse clock frequency.
further, there is such a thing as laser cooling, it is possible the 10^18 laser pulses per second that advance the clock/automata computation could be a kind of cooling laser pulse, causing numerous benefits.
light based internet repeaters and data gatherers: the 10^18 externally pulsed photon PV effect refresh/priming thing could be used at data photonics to make detectors that are able to receive optical data at 10^18 or higher pulses per second. The semiconductors are similar to the 10^18 CPU. this benefits the internet.
subratractive nodal contrast enhancement
Artificial heart coating: Immunopassivators exist like published hyperbranched lactose glycopolymer (as well as a phosphatidyl one I do not know the name of), lining the chambers of an artifical heart with a polymer: poly(hyperbranched lactose glycopolymer) makes it so there is less immmunoresponse to an artificial heart or other artificial organ or bodily implant such as breast implants and things that prop circulatory system tubes to fuller diameter.
projector and base
Iontophoretic breast cancer RNA drug treatment and diagnostic iontophoretically psuhable apatemers/antibdies, and an electrical bra that does iontophoresis; Iontophoresis is able to transport drugs 1.5 cm in 20-30 minutes, so 14 cm in a number of hours (48?), makes for a wearable cancer treatment bra that does continual electrophoresis until the RNA drug reaches physiologically active concentrations at the tumor site, perhaps picograms,
Similarly a laser visiblizable scannable indicator antibody or aptamer could be iontophoretically delivered to the breasts with a 48 hour iontophoretic bra, making a map of all the possible tumor sites
up to
at people who were previously alive put their previously alive bodies in the right side circle of a tricircle or bicircle, wwhere there the diagram is light blue and the rightmost circle is cobalt blue, then leave them there (like at a mausoleum), optimally the body is crygenically suspended for revival.
interleaved search engine browser extension, takes a search engine result (bing, google, yandex) and then makes every other displayed item from either a custom internt snapshot local to the computer (or at the cloud) such as archive.org regular expression search, or a Search bing, interleave Google, search google, interleave yandex. Archive.org could publish a read-only clone of itself at the cloud, then programmers could write custom search engines, like regular expression search around the archive.org data to make better search engines
Breast cancer and other cancer early detection scanning technology: systemically adminster quantum dots that aptamer-glom to the kind of tissue behind the breasts, I'll call it fascia. When stimulated with EM/RF the quantum dots glow brightly making "flashlight fingers" effects at the breasts. A camera then looks at the flashlight fingers view of the breasts and software looks for anything out of the ordinary. narrow area sampling: It could be that activating the quantum dots at the fascia at a .1mm area could rpovide better data and higher resolution to the optical scan; a flying raster spot of quantum dot activation of EM (narrow beam radio) causes just a thin column of breast tissue to emit light and be scanned at any particular moment, and the entire chest is sequentially raster scanned.
quantum dot personal care surfactants and doorknobs; doorknobs release minute amounts of quantum dots and the person is then likely to touch their face; quantum dots at shampoo bodywash leave quantum dot residue. Scanners learn things like continuous medical screening from EM/photonic "call and response" to the quantum dots. Social companion robots are better able to read the affect of humans they interact with with a robot-readable quantum dot contrast enhancer for emotion detection
contrast enhancer for truth detection: quantum dots at facial moist towlette provide much more data to scanner than IR thermography (patent) alone, possibly erector pilli information,any chemicals that get produced and secreted at the face when telling the truth (lack of cortisol), even microperspiration.
here is a novel social companion robot emitter and sensor: facial expressions throughout the day could be recorded and the day's affective content detected if the human has a minute coating of quantum dots; comparing the AM position of the dots with the PM position (like facepaint cracking at smile lines) shows what emotions have occured throughout the person's day which benefits social companion robots nonsentient imitation empathy, fun, and conversation.
Noting the Sundet heritability cycle there are likely some kinds of environmental influences on genetics. Blue zones are places where the people live the longest, like Loma Linda, California, at a zip code map of the US (and other countries) find the areas with the very longest lifespan, and areas with the shortest lifespan; then raise mice in modules at each of these types of longevity area using the same source of water as the humans. If the mice show longevity effects then they can figure out what about these areas causes longevization, notably doing things like putting the mice at a Faraday container, and comparing water constituents; this protocol would have found magnesium in water reducing cardiovascular disease and lithium in water correlating with longevity; the novel thing is that it may not have a reflex answer but be a new to science basis for longevizing the mice. Once they find out the longevizing agent it can become a human longevity increasing therapy.
artficial heart linings of polymeric version of immunofreindly phosphatidyl
Also of course there is the possibility to remix the 3-7 assemblyline segments together not for highest quality but for sustained high average quality (very narrow high-z distribution) so the cars tend to come out the same, but not as exsquitite as the 80/10 optimized 3-7 assembly line.
toxomplamsosis test is sticker to put on cat litter boxes, also general medical test during month/2 weeks of pee and poo sticker to put on cat litter boxes, especially valuable in dwellings where people are planning a pregnancy as stopping toxoplasmosis reduces mental illness in humans.
Hoberman sphere, or rather circular pad bed comforter: people put comforters on beds, and there are cartoons about some person of other getting all the covers, with hoberman comforter covers the cover can expand to 3 times the area of the bed if necessary when pulled on; hyperelastic or gathered fabric cover over hoberman mechanism,the elastic cover could be comfier if it were microflocked with corduroy that expands to velvet
do mRNA have a spectroscopic absorption peak (like IR spec or other frequency) where illuminating an mRNA or RNA drug with that wavelength causes greater mRNA (or RNA drug) activity different than a warming effect? maybe, maybe not, if so then a corraborative to an mRNA drug is is illuminating the drug at the body, or at test yeast or c elegans or human tissue culture to make that mRNA even more avidly transcribed, or if another RNA drug, active as a drug. So beam light into the tissue or organ (brain, heart, COPD lungs, tumor, vasculature, dermis beauty treatments) that has RNA drugs in it, to make the RNA drugs more effective and dose potent. isotopically unque RNA drugs (locational deuteration) could have a different stimulation frequency than the rest of the RNA at the body, making the RNA drug spectral absorption unique and individually addressible. If this actually works then bodywide illumination might get rid of metastatic oncocytes reducing cancer risk and spread, as an adjunct to a RNA drug that makes epigenetic changes, like benficial longevizing epigenetic changes, the stimulating frequency could make epigenetic change more thorough or faster or more dose-potent. aptamers and antibodies (like anticoncer antibodies) could have spectral stimulation wavelengths as well, making them function better. if nonthermal photostimulation does not occur in nature RNA drugs could be attached to nanoantennas or quantum dots for similar effect.
25k genes code about a million proteins at the human body, compare the versions of those proteins at a 9 year old and a supercentenarian to find out if there are any differences in the proteins and membranes produced other than amount and ratios, there could be a post-translational processing of cell components that varies with age (endoplasmic reticulum, gogli apparatus) causing the actual proteins and membranes to be different among the elderly which can be restored to 9 year old form using improved endoplasmic reticulum and improved golgi apparatus. Improving the endoplasmic reticulum and golgi apparatus can be accomplished genetically or epigenetically. That could be a longevity and rejuvenation technology. as a simple approach, at plurality of human tissue cultures of the same cell type, but from diferent humans, find the 99th percentile of endoplasmic reticulum and gogli apparatus size (or other morphology like crenellationness), then see if that cell tissue culture has any advantages, if it does, then that enodplamic reticulum and golgi apparatus size and morphology is a thing to test at mice to see if it benefits them.
Higer dose PQQ could increase sperm motility, especially at genetically enhanced sperm, from making the mitochondria work better. simply mixing the sperm with PQQ might do it, or if at a human sperm donor, daily PQQ supplements over 90 days of spermatogenesis.
does an apparatus that makes photons like a laser and then observes them into particle-ness but lets them pass through cause particle photons to pass through tissue? These particle photons might diffuse less, assisting with drug activation and imaging, like brain imaging such as a photonic brain reading and stimulating head circlet. One technology that might do this is passing through a transparent crystal that has photlectric effect; passing lasers through a frequency doubling crystal might give them all wave effect.
the internet says, " One way of resolving this question might be to aim two "particle detectors" at each slit, in the hope that we can determine what emerges from each one.
This kind of experiment has actually been done, both with photons and electrons.
The result is even more weird: the quantum-nature of the particles disappears.
They act as if they were baseballs!" and, "Now, repeat the last experiment, making only one change: turn the particle detectors off.
Voilà — pulling the plug on the particle detectors restores the quantum nature of the particles.
So apparently, the particle somehow "knows" that it is being watched, and reveals its wave-like nature again." so a switchable detector could make a laser either all particles or all waves, or sequences of both.
"Its small mass (9.1E–31 kg) made it an obvious candidate, and velocities of around 100 km/s are easily obtained, yielding a value of λ in the above equation that well exceeds what we think of as the "radius" of the electron. At such velocities the electron behaves as if it is "spread out" to atomic dimensions;" so, what is the effect at an electronic device or inductor/generator/motor of having the electrons go so fast they are "atom wide"? unknown, but could have technology applications; think of a magnetic generator winding, but have it be hollow optical fiber, make a plasma in the long wound hollow fiber, that is the conduction pathway for the atom-sized electrons; plasma does not breakdown or melt, so the voltage and current it can carry is very high (lightning at fiber optic width is an example) the hollow tubes could be made out of silicon nitride or highest melting point glass or ceramic; better generators and motors; possibly even smaller transformers
Longevity technology: epigentics of increasing autophagy is a published thing, and making more of the "limiting step" component in autophagy would make that better. hibernating mammals could do much more autophagy seasonally and make autophagy inducing chemicals that can be repurposed as longevity and wellness drugs; parabiosis of autophagy; fasting rat attached to circulatory system of normal fed rat, is there increased autophagy at the normally fed rat, if there is then there is a circulating chemical that promotes autophagy that could be used as a longevity and wellness drug.
Longevity technology: drinkable stem cells: liposomes or someothersomes that pass the GI tract contain the stem cells, stem cells use oxygen to live, so 1:100 ratio of stem cells to an oxygen carrier like perluorarbon fluid/colloid at the drink (and pure ATP or glucose as nutrient) is used to keep the stem cells alive, one procedure: laxative first, then nonstem cell perfluorcarbon colloid, then administer the stem cell perfluorcarbon combination, I read vibration causes things to pass memebranes better, the sonication or ultrasonication of Gi tract through the abdomen could increase 2-4 times absorbability; put cell-passing peptides on outside of liposomes and possibly on the stem cells, put tissue localization peptides (brain) on outside of liposomes or on stem cells to heighten utility. possibility that breathing 100% oxygen during 120 minute procedure improves oxygenation of stem cells and their thriving at GI tract, is it possible to turn down filtration of kidneys, enema/fecal transplant-like delivery could also be possible. does increasing or decreasing blood pressure change the diffusion of liposomes into capillaries? if so that could be a +20-29% upward adjustment of absorption. 700 grams of perfluorcarbon liposome stem cell combination could deliver 7 grams of stem cells to the circulatory system, perhaps more than is plausible to inject.
perfluorcarbon polymer liposomes could be oxygen enriching and transferring at the liposomal package and assist with oxygen diffusion to the cells inside the liposomes or someothersomes.
New physics: find the Godel exception (loosely math can't prove itself, perhaps others) to Noether's theorem, then look for physical systems that would embody that godel exception, these physical systems then might have an absence of similar behavior at different spaces (a 20th century physics Noether math "assumption") ; use telescopes to detect these non-similar space embodiments at the universe; make noether exception technologies in the laboratory to create new technologies. lets say the laboratory studies find Neother exceptions that cause things to happen faster or slower, but without relativity time dilation methods, that is a time technology independent of gravity; there could be MWI applications as well, based on time technology and other technologies; Neother exception technologies and science could effect things like planck interval and planck length, packing more (or less) activity into a space, at MWI 1/100th sized planck lengths or 100 times sized planck lengths could effect MWI universes generated, and their further branches, as well as possibly their individual universe unique physics (an MWI branch with 1/100th planck length or also interval would have more possible states, causing all MWI from that branch to be more multiplied, and, with anthopomorphic principle used to design the new MWI universe, the much faster propagating MWI could be much nicer than the one I was aware of during my enjoyable 20s.
100 or 1 million times larger planck length and interval from Noether exception technologies could possibly make further verifications of the MWI, by making the branching more visible to an outside, 2021Ad planck interval observer; basically the new MWI comes into being 1 million times more gradually and can be studied as to what is going on with it.
Virtual particles, being numerous, even transfinite in number at a laser doing a double slit experiment do not seem to make MWI universes; does creating an MWI universe in a chamber full of virtual particles change the functionality of the virtual particles (desaturating or saturating them, making them more likely to immanentize as path) do virtual particles care which of two laser beams they arise from? Billion or trillion parallel channel, but space separated photonic output, double slit makes virtual particles around the photon path, does a billion of them hypersaturate the area with virtual particles? Does hypersaturation with virtual particles cause numerically measurable anomolies in where the observed wave pattern appears on a screen, diffeent caisimir effects, does hypersaturation of virtual particles to densities above the planck length have an effect?
wikipedia says, "Therefore, many push-pull olefins exhibit high TPA transitions, up to several thousand GM.[14] It is also found that compounds with a real intermediate energy level close to the "virtual" energy level can have large 2-photon cross-sections as a result of resonance enhancement." suggesting virtual particles density and overlap effects have testability. or I may misunderstand.
Social companion robot sensors: two photon imaging (TPI) has been used to look at the vasculature of mouse brains, resolving to the size of capillaries, TPI has spatial depth, so it makes a see deep into things technology, beneficial to social companion robots. looking at arteriole dilation at the face or other parts of the body could communicate parts of the affect of the human being to the social companion robot.
Could through-the body imaging like TPI work better if the body emitted light; big oral dose of a UV fluorescent chemcial could generate light internally with UV "flashlight fingers" stimulation, then detecting it from the outside of the body.
Is there an analog to spatial depth TPI at magnetism? There are magnetooptical effects. If so then a TPI-like magnetic read/write head could address, and see hard disk domains at depth, permitting, based on seeing RBC thickness things with TPI, several powers of two more data to be written and stored on a magnetic platter's domains. the 1024 TB hard drive.
massively parallel read/write heads (made with MEMS) cover entire surface of disk platter all at once, and when piezo vibrated do microscanning for their minute individual parallel area (chunk of domains); a 1024 TB HDD could use a parallel arrary of reader/writers to do chunked random access to HDD contents, preferable to serial access.
Recording changes in affect all day long could come from an adhesive removable skin jewel that goes on the face, or above hairline and has fisheye lens to get most of the face and does TPI imaging as well as facial expression and vocal tone recording. uploaded to the cloud all that data could be processed make an all day (and while asleep) record of emotional well being, and drugs that improve emotional well being could be tested as to their all-day effects. Social companion robots would then also have a full's days (and more data) on how the human they interacted with responded to things resulting in suggestions from the social companion robot like "you should play more with Hillary, she makes you happiest", or "you actually enjoy talking with your supervisor, talk to them more, it frequently leads to promotions", "when you talk to your spouse some of your three most enjoyable topics are:1,2,3"
At phone cameras TPI could cause the ability to have multiple focal planes (like a lytro camera) but without all the lenses and much fewer optics, multiple focal planes make it so at an image each layer can be in focus, and then photocomposited to make an everything in focus all the time phone and video camera.
I have not heard of catalysts that are regenerable with light, like super bright light periodic pulses in a chemical process industry reactor or petroleum CPI; wikipedia says avobenzone switches from cis to trans form with light, and imaginably if you just stuck a metal atom (Co) on each end of avoebnzone you would get a catalyst that changed shape and activity with light, rapid pulses of light toggling the two forms could cause rapid molecule shape change, increasing "charge slosh" and make the catalyst even more catalytic. Two avobenzones, one isotopically modfied, the other not would have different activation light frequencies, and connecting the two avobenzones with a linker molecule, perhaps an alkane, would isolate the two responsivenesses such that you could get the catalyst to take on any of 4 shapes (cc,tt,ct,tc) and have wider varieties of "charge sloshing". a light tunable CT flex catalysts could also be sueful in non CPI things like drug manufacture to increase or generate preferred yield ratios.
I read about conductive Si electrodes at batteries; Si is tranparent to IR, and using the electrode itslef as a light pipe to bring oscillating part-of-the-battery laser light to avobenzone-like shape changing molecules at the surface of the electrode causes those oscillations to make it so that at-electrode battery chemistry is refreshed and dendrites omit forming; intestingly there is also a very direct approach; IR lightpiped through the Si electrodes warms the faceted electrode surface, rapidifying chemistry, which could effect not only dendrites, but the heated microlayer of chemicals could make recharging happen more rapidly.
vehicle catalytic converters could work better with different surface textures of the catalyst such as the exhaust stream optimized versions of the hydrophilic \_/ and hydrophobic ||||| surface textures and microswirlers that make higher stochasticism at the siwrls of gas right next to the catalyst.
could the natural high pressure of exhaust drive a hilsch vortex tube? perhaps, perhaps not. If so it would be possible to get a superheated stream of exhaust off of it to superactivate the catalytic converter, and at short 11 minute trips turn lukewarm exhaust into a hot and cold components where the warmer component is warm enough to activate the catalytic converter, that makes the catalytic converter at least partially work even before the engine is warm.
a custom chemistry catalytic converter could address not only pollution, but which componets of exhaust to subtract (like sulfur to least S smelling chemical with additional catalysts) to make it neutral or even good smelling. that would benefit the odor of cities. I favor switching to all electric vehicles.
could coanda effect fuel injector nozzle apetures cause a different, eentsier size of microdroplets at droplet formation, or could a fuel injector have a coanda effect air-pulse generator that microcomminutes fuel droplets, or could ultrasonic beams inline with the exit surface of a fuel injector acoustically comminute microdroplets to be even eenstier in size, improving efficiency and reducing pollution.
Longevity technology: what lobsters haven't got that makes them "cessationless": Lobsters likely have a nearest relative that shows a life course which includes not being alive; compare the genes of that nearest relative with the lobster; find the difference, see if the lobster is actually good at omitting a cessation program (or having a broken cessation program) rather than being good at regenerating. Find the system connections of the cessation program lobsters omit, and find homologous genes, or homologous gene deletions, to make "absence of cessation program" at mice and humans; then install or delete the genes in mice that make the cessation program do its thing so the cessation program ceases working. See if the mice live much longer.
Million-100K year endolith fungi may also be absent a cessation program, find their nearest living relative that can expire, and look for the genetic differences, just like the lobsters.
Queen bees and worker bees share the same geentics, but queen bees live more than 11 times longer (termite queens might live 25 times longer), find out if royal jelly knocks out, or epigenetically modifies a "cessation program" at bees, causing the much greater lifespan. then, similar to the lobster version, delete or modify the genetics and epigenetics of mice at the homologous genes of the cessation program, if any.
The connections (connectome of proteome) provide many places to knock out a "cessation" program and provides multiple locations to break a "cessation" program, and can be specifically addressed with drugs, like RNA drugs and epigentics like hypermethylation of cessation program components to shut "cessation" program genes off. of those genes protein products could disrupt or break any mammalian cessation program as well as new longevity drugs; the new drugs and gene therapies disrupt the "cessation" program to see if it cause mice to and humans to just live indefinitely, like lobsters. If it works really well getting rid of any Cessation program at the human germline is beneficial to make at all humans and human branch species, if any.
TPI iamging but uses TPI to activate, that is open up liposomes at particular brain areas, very high degree of brain loaclization, nootropics, antipsychotics, sex drugs, antidepressants, recreational drugs, anti-ADD,
TPI imaging of the human brain during IT pattern recruitment find the brain areas that link in parallel or sequentially at an IT pattern recruitment event, then make drugs with brain localization that preclude that parallelism or also sequence which then precludes pattern recruitment,
LEF (lifextension.com) has a pill, Daily Skin Defense, that they say causes 10x less wrinkling; does the interior of the body wrinkle? if internal wrinkling is deleterious then the beauty pill could also be a wellness pill. all the plant extracts in the LEF beauty pill could be replaced with pharmaceutical ingredients, perhaps bringing it up to 20 times less internal and external wrinkling. people could get a depot injection when they are 14 that lasts until they are 200. (halogenated ethynylized drugs or RNA drugs at depot, more than one depot site could be utilized)
math educational software: portable desk camera watches person write their math work on piece of paper, notices if they are doing their equation wrong or amiss and provides a tip or sub-equation part broadcast on the paper with lasers/microprojector. Its possible pencil and paper works better than tablets at doing math homework so this makes paper math practice cued just like software. computer notices avidity and flow of doing math homework, and then introduces new math topics at the most learning receptive moments.
Note to the Singularity: along with reading all the science and math papers the Singularity can use human money to commission new scientific experiments, and, collaborating with a human as co-inventor, patents can be obtained.
The singularity: a singularity type thing, the ability to run a million nonsientient human mind variations in parallel on a computer causes the ability to have, slightly entertainingly, the ability to list a million new profiles at gig-work sites like 2021AD fiverr.com the kinds of questions people ask of the million nonsentient human simulations at UpWork could be a basis for finding out what humans really would like, independent of what are called the academic humanities. Similarly a million nonsentient simulated minds running on computer could come up with ways of asking all the sentient humans on earth what they want in a manner (nonaversive context making pre narratives and prompting) that actually gets the people to say what they want, then the million simulated minds could do those things, and make those things happen for people. It could connect people to people as well, like a person that wants a happier marriage could be connected to both a human marriage counselor as well as simulated marriage counselor. A person that would like to be gorgeous can be connected to cosmetic surgeon. A person that wants to be rich could be connected to an an actual investment opportunity, like being the titleholder of an Isle of Man commercial (skyscraper) trading and accountancy company. The Singularity benefits from finding out what people want, and what happens when they get what they want, so with that data giving people what they want is convergible on a 99.9999999% have better lives after getting what they want from the software. The software could run a million 99.999999th percentile light triad psychology test scorers in parallel, and then the software could ask the light triad simulation to inform it on giving people what they want, as well as coming up with completely novel mathematics that reconcile what's good for you with what you want.
One such novel mathematics is a variation on central place theory; the person could voluntarily move to an enriched environment that reinforces and inculcates things that were good for them, and the software could notice higher happiness levels and higher light triad levels simultaneously in people who asked for things after they had tried out a voluntary move to an enriched inculcating environment. More than going to college on a green, the enriched environments could take many forms. Central place theory comes up because locating the voluntary inculcation environment near and between population centers makes sense
New kind of laser: when an atom emits an emission spectra it seems like it exits the atom, but what if the emittted photon actually has any directionality, including a possibility of travelling towards the nucleus and passing through it or energizing it (reabsorption). If there is some way to customize the amount of centerward photons or outward only photons then that could increase the efficiency of lasers. a semiconductor laser dielectric or mirror sandwich could cause most photons to go centerward; perhaps even a monoatomic lasing layer, then a dielectric layer or mirror on it causes majority centerward motion of photons. some of the time the actual atomic nucleus would interact with the centerward photon, and this could, or just might, effect isotope stability and rates of radioactive decay. x-rays can already make things radioactive showing that the nucleus does absorb photons, so perhaps some much less energetic radiation like visible or UV if made centerward could also cause radioactivity. lots of layers of this make Atomic batteries as a possible application.
a separator https://en.wikipedia.org/wiki/Separator_(electricity) is a thing between anode and cathode at a battery that permits ion flow; PVDF is one published material and it seems possible that a piezoelectric polymer could be made to vibrate slightly, facilitating ionic solution motion; also piezoelectric battery separators could be turned to high vibration during recharging for faster recharging. Electrowetting could be a feature of batteries and battery separators as well, so like the separator would get electrowetted n times per second.
at solid polymer electrolyte batteries things would work better with better ion conduction; could irradiating the polymer (cellulose is one of many) punch little holes in it facilitating ion migration?, so basiaclly x ray the solid polymer electrolyte until it becomes more porous, with more holes. "cellulose or PVDF or other solid electrolyte doily"
quantum dots on solid electrolyte pores can be stimulated with RF radio to make the solid lectrolyte more permeable, or not.
Sperm technology: oxygenation of sperm and spermatids for longest lasting sperm diffusive vaginal insert like cervical annulus: if 99% of the liquid medium is oxygen carrying perfluorocarbon then at 1% of total oxygen a day being sufficient that is 99 days of oxygen for the live sperm or spermatids that the cervical annulus diffuses out, also it may be possible to engineer a perfluorocarbon that maintains constant oxygen levels over 94 days; a paper says, "In spermatids, quercetin inhibited aerobic glycolysis only by 40%, even at higher concentrations" that suggests that if the sperm live just as long or longer on reduced sugar metabolism that 40% less oxygen could be used at the sperm diffusing cervical annulus
Do sperm from hibernating mammals also slow down metabolism at sperm? if so then that could be a source of chemicals that make human sperm "hibernate", thus lasting more days at a cervical annulus sperm diffuser getting people voluntarily pregnant with enhanced or optimized human genomes
crowded desk computer mouse detector and motion compensator; sometimes my desk is cluttered and I find that the amount of are to move the computer mouse in is not very big. This causes more stacatto-like mouse movements and lots more lifts and starts to traverse the page space. Software could detect when repeated very short mouse moves concatenated to a destination (that is, detect cluttered desk user behavior) and change the numeber of pixels traversed per mouse sweep upward, say 2-3 times. I figure there are more than 3 billion computer mouse users on earth, so if this assists .5% of them that is 15 million mouse users.
A weave of glide strips (like razor glide strips) with a deliquescent polymer (pulls water from air) could be at an around the finger tip (one finger tip) clitoral super glide sex toy for women, particularly at the developing world where it could be less than 1/10th to 1/20th of a cent each and be reusable. The deliquescent polymer pulls water from the air so that the surface is always wet even without wetness on the rubbed surface. NaPCA is a deliquescent amino acid PolyPCA could be a polymer version for use at the masturbation pleasure finger circlet. A number of exisiting deliquescent polymers are described online.
at battery spacers between cathode and anode, and at solid electrolyte batteries they could study the use of deliquescent polymers (not just water, other solvents' deliquescence as well) to see if hyperwetting of the pores causes any greater ease of chemical ion motion. This is ignorant, but perhaps at a battery, driving characteristics of the separator like electrowettability/solvent deliquescence/piezomotion/physical warming (or peltier thin film cooling) with high frequency AC (or light) would not interfere with the much larger bulk DC current and voltage. memory plastics that change form (like fluffy to thin dental floss) could also facilitate ion movement.
consider a weave stack of polymer, like a sugar wafer of different memory polymers and piezoelectric polymers; the stimulus (warmth, electricity, acoustics) causes the polymer weave to alternate between very open and very nonpermeable (similar to fuzzy dental floss that pulls to linear flatness); pulsing the sugar wafer layers in different purposed orders ))))) could cause a physical pumping effect of the electrolyte between anode and cathode; genetic algorithm optimization for fewest thinnest layers; also MEMS battery dividers could do this
deliquescent quantum dots; QD RF or light antenna linked to a deliquescent chemical could make a fluid drawing and push-outing microstructure; line pores with these pumping quantum dots to transport ions faster. The cheapest quantum dots I am aware of are from polyethylene glycol and may be used at the oil industry downhole, so it is possible a deliquescent quantum dot could be cheap.
another possibility for battery separators is to use a genetic algorithm to find a optimal channel size to structural material density ratio, perhaps a simple staggered grille could be the starting seed to calculate from, and a version that emerges would be a docdecahedrons pack 3d space with largest aperture gaps while still being structurally strong. The genetic algorithm would also use chemistry modelling software to find out if neutrality or charged electret surface at the separator was beneficial. Cheap: Make a collid with camphor and polymer; have the camphor be the emptyspace shape (laser mill cool camphor shapes); the camphor sublimates out, leaving the optimal sized emptyspace shape with a polymer lattice around it; many other chemicals besides camphor sublime (flurobenzene?) at near STP for processing cheapness.
Could electret nature at anode and cathode and separators change (reduce) the amount of nonoptimal dendrite growth at batteries? Maybe.
I must be missing something here but instead of having a separator at all could you just have a fluid gap between anode and cathode and the anode and cathode so immobile they never touched. you could even have | | the anode and cathode "pillars" have a supermagnet in them so they were strongly attracted to the non-touching direction so catastrophic vibration would just make the gap wider. as a cheap separator, a pile of MEMS jacks, or dendritic polymers could be a simple paste to apply between anode and cathode layers at "poured" batteries.
dry superacids and superbases exist, and could be coated onto battery separators to see if they have transport faciliting effects.
the internet says, "as the technology developed the thickness of the separators got reduced down to 20μm, 16μm and even 12μm without compromising the cell properties." that suggests that a genetic algorithm sampling different polymers and gemometries could be used to make 6-7um thickness separators from genetic optimization, I perceive the thinner the separator the more facilitated the ion movement, the faster the recharge.
A patent says, "Stated another way an effective separator membrane must exhibit a low electrical resistance when in the battery. The lower the electrical resistance the better the overall battery performance will be." There is a kind of semiconductor that produces negative resistance, and it is possible quantum dots could prodcue negative resistance; (negative) ion (travel) resistance at quantum dot coated battery separators might be possible, I read about negative resistance as an electron phenomena, but it *could* also be a proton conductor, ion conductor phenomena. Negative resistance could make batteries better. negative resistance is aassociated with oscillation, suggesting a pulsatile battery recharge e- could provide the oscillation. The internet says, "Gunn diodes have negative resistance in the range −5 to −25 ohms" So, is negative resistance possible in positively charged ions (proton-conductorish) and if it is, can this be used to make better batteries, notably better battery separators from ion travel negative resistance. one negative resistance material, besides semiconductor diodes is, " negative differential resistance in biased zincite (zinc oxide) point contact junctions"
Perhaps they could be less concerned with runaway battery overwarming with fiber optic IR camera weave at big battery packs like electric vehicles that spot IR anomolies and then use multiplex addressing to exclude that particular battery cell from being used (sort of like known dysfunctional sector HDD work-around-it), fisheye lens also possible IR imaging approach, that would make the individual batteries more efficient as they could omit some of the chemistry that automatically stops them from melting, making more latitude for battery chemistry and separators that recharge the fastest.
A battery thermal shut down technology different than a separator technology could be little microparticles in the electrolyte that plump when overheated, increasing visosity greatly, and blocking passage of most battry ions from moving anywhere, including across a separator membrane. "Popcorn safety" dendritic polymers, and memory polymer ultramicrobeads, even nanobeads could do this. moving the thermal shut down safety function away from the separator makes it possible to have more efficient and different battery separators.
genetic algorithm optimization of reverse osmosis membranes like desalination membranes could make them half as thick, using half as much material so be twice as affordable; starter seeds of 1/4 thickness of usual desalination membranes ; is high deuterium plastic/polymer stronger? It might be, so that could be another genetic algorithm seed is deuterated polymers. does deuterated polymer crystallize differently, if so, are any of the alternate crystallinties advantageous?
wikipedia describes the gyrator https://en.wikipedia.org/wiki/Gyrator , and says it can be made with op amps; gyrators can replace transformers, so is an all semiconductor gyrator circuit that transforms electrcity more or less efficient than a magnetic transformer; if it is more efficient then consumer electronics transformers then it could replace magnetics at these transformers and make them physically much smaller in size. what is the meaning of replacing a generator magnetic field with a gyrator? is it possible to built a proton or ion conductor gyrator circuit?
Ferrites have multiple electronic uses; could isotopically different forms of ferrite (differernt Fe, different O) have different effects at things like generators and amorphous transformers and motors?
making ionic crystal near-ferrites that might do new things: have some Fe ions and O ions in solution, such that it reacts to produce ferrite; then change the reaction to reduce the available Fe from 2 to 1 and the O fromm 3 to 2, (chelation of ions is one approach), dry the fluid out so the Fe(1)O3 and Fe(2)O2 ionic crystals remain, test them for the functionality of ferrites, they could have completely different latitudes of ferrite behaviors
think of an inductor on a circuit board, ir physically looks like a little spring; could the length and volume of the inductor spring be halved or quartered if the inductor itself had a spiral, or other winding around the )))))) wires of the inductor carrying electricity; if so then wire inductors and some transformers could be made smaller, aming for smaller devices like wall plug-in transformers. genetic algorithm to find optimal geometry of the coiled, or other path sheath-on-inductor technology
Sometimes when you look at an inductor on a circuit borad it looks like a little ballpint pen spring; what would be the effect of halving or quarter the length of the spring, and nesting the continued voltage path to be a coil inside the other coil? Magnetic modelling software and genetics algorithms could find concentric nested inductors that function as well as linear spring-like inductors but take up 1/4 to 1/2 as much room.
Generator transformer and motor dip; ferrite potting polymer; square and hexagonal wires: lets say a tightly wound generator of transformer or motor 7-11% airgaps between the sperherical cross section tube wires; that is wire piles made of round wires always have the space between circles as extra space Is there somethings that could be put in that extra space that would improve the efficiency of the generator, transformer, or motor? One possibility is a ferrite-polymer just soak it in potting compound that improves the electromagnetics of the wirewound device (generator, etc); similarly consider the 7-11% higher conductor density if square wires, with no interstitial gaps, were used to wind a generator. that could be 7-11% higher magnetic flux at generators or smaller form factor to produce the same amount of motor power. I made a .5b idea about 3D printing motors as well, so the conductors can be any shape. Square or triangular or hexagon wire with 7-11% less empty space compared to round could also make MRI machines have higher fields with smaller form factors.
I think that halving or quartering the expense of crushing ore rocks into fine powders would make most raw materials much cheaper, benefitting humans. One kind of ore crushing machine is a an angled > crusher plate (wikipedia jaw crusher), It is possible that rather than just general feeding of ore chunks to the crusher plate that if they load rock in order of optimal size to produce the most fines more reducible ore fines can be produced more cheaply. One possibility is putting the biggest rocks near the angle origin, or, combine large and small rocks to break rock against rock to increase fines proportion; genetic algorithms could try out many different blends and heights of communituted rock sizes at various lever-disatnces from the > angle of the jaw crusher plate; to sort the pre-crush ore chunks cheaply use binomat and gravity or centrifuge to sort rocks on size (and shape); chlandi vibrations at the plates of a > crusher plate could have an effect; genetic algorithms applied to jaw crusher plates generally could produce improvments. To customize the: which chunk size where at a jaw crusher angle >, highly pressurized air could be blown through side holes at the jaw crusher > plates causing smaller comminuted chunks or fines to be be at the optimal location in the jaw crusher. Blow the dust and half centimeter communitions to the top for a refluxing-like re-serial decrease of particle size. Another possibility to push the rocks at a jaw crusher faster than gravity feed is to use a tamping wedge \V/ the tamping wedge could move chunkks faster than gravity downwards, and computers could look at ultrasound of the rocks in the jaw crusher and decided when to use the tamping wedge for optimum mineral crushing.
It could be possible to double the velocity of jaw crushers by blowing, with air or water, the rocks into a different section of the jaw crusher > during the opening phase, that makes it faster than gravitometric feeding. piezoelectric vibration could also make the rocks unstick to one another in a jaw crusher, increasing velocity of comminuted chunks travelling towards the > base.
making cone crushers work better: genetic algorithms, eccentric motion could come from a novel motor winding that produces ~ circle (camlike) motions at the its-not-a-solenoid driven object. The novel winding motor and not-a-olenoid makes it so some of the mechanical linkages at a cone crusher can be omitted, making them cheaper and possibly have longer lifetimes.
Cone crushers and jaw crushers use gravity feed; but if they were placed on a platfrom that vertically went up and down they could also get the dwelling building elevator "press down" and float up effect perhaps increasing the equivalent to G force 2-4 times making them be able to function twice as fast or faster; so just put a big actuator under the jaw or cone crusher machine and elevate it and cycle it back down; eccentricity in the big up-down actuators motion (perhaps circular motion along with up and downness) could have some beneficial efect on rock crushing as well.
wikipedia says, "Modern, automated sorting applies optical sensors (visible spectrum, near infrared, X-ray, ultraviolet), that can be coupled with electrical conductivity and magnetic susceptibility sensors, to control the mechanical separation of ore into two or more categories on an individual rock by rock basis." so along with those they could do THz imaging, and something new to me, using a laser to heat up a spot on the rock, and then mapping the diffusion of the heat in the rock with an IR camera; two photon x-ray microscopy and 1 cm depth techniques could be used with two photon x-ray systems to find very specific things in comminuted mineral chunks.
opposite of a surfactant assists with dewatering ores; pH differences likely have different wettability from different amounts of H+ and OH-, change the pH of a slurry to be dewatered so it is anti-compatible with surface particle charge, if any, one cheap way to make varied pH fluids is electrolysis of water apparatus where variously OH- and H+ enriched water occurs at the anode and cathode, so just draw off and use the near cathode surface water to have a different pH.
holographic explosives and making optimally sized chunks at first exploding rocks out of a mine: 2 or more explosives set up a standing wave pattern (interference) with high peaks likely to cause fracture and division of rock chunks at regular comminuting intervals, computer modelling describes how to make the explosives that do this, and their 3D communitution effect. a jello mold-machine in the mine could continuously make holographic explosion jello blobs, rods, and planes. the explosive jello molder could do things like have bottom half ANFO1 (anfovariant 1), middle part ANFO2 and top part ANFO3 wikipedia; the jello mold could make things as complex as millifiore shapes at the explosive holographic jello. (shaped chage) Wikipedia says mines often use ammonium nitrate fuel oil explosives because they are cheap; consider the effect of putting multiple trans inflections on the fuel oil alkane the molecules shape changes and it might be differently and more explosive, also of course, what length of alkane at the "fuel oil" makes a difference, higher peak amplitude pressures seem likely to be better at blasting more rock into fragments. I do not know anything about ANFO but it is possible that either octane or 20-ane would be better than the other at things; this also customizes "dwell time" and ammonium nitrate duration of explosion;
bioswales and algae at former surface mines; also drones carry soil to mine surface providing a toplayer for plants to grow: bioswales are a thing; machines could either pile up gravel or drill out a @ bioswale where water is likely to acccumulate or run through, to colonize the bioswale with plants drones could get nonharmful amounts of topsoil from the area around the mine and coat the bioswales and between bioswale area at the former surface mine so there was a plant growing medium, and the drones could broadcast seed at the bioswales
better gyratory crusher; lissajous overlap of waves produces (O, (XXX)) shapes and the little extra spriogrpahy corners of a lissajous figure suggests energy concnetrated in space (comminution energy), also I read that ad adding three ~ waves the output goes from detreministic to stocahstic looking, with ocassional high spikes of energy; If it is posssible to set up a threee trigonometric simultaneous wave rotation at a hyratory cursher or use the rich corners of a lissajous it could crush rock more efficiently.
Genetic algorithms and human engineering could make versions of eccentric motion and spindle, concave liners, and mantle line, and plate shape; it is possible to match the eccentric lissajous wave in a box thing to the ore/hardness/comminuted chunk size.
Wikipedia says, "A gyratory crusher is one of the main types of primary crushers in a mine or ore processing plant. Gyratory crushers are designated in size either by the gape and mantle diameter or by the size of the receiving opening. Gyratory crushers can be used for primary or secondary crushing. The crushing action is caused by the closing of the gap between the mantle line (movable) mounted on the central vertical spindle and the concave liners (fixed) mounted on the main frame of the crusher. The gap is opened and closed by an eccentric on the bottom of the spindle that causes the central vertical spindle to gyrate. The vertical spindle is free to rotate around its own axis. The crusher illustrated is a short-shaft suspended spindle type, meaning that the main shaft is suspended at the top and that the eccentric is mounted above the gear. The short-shaft design has superseded the long-shaft design in which the eccentric is mounted below the gear." And of course doing genetic algorithms on gyratory crushers with multiple simultaneous eccentrities could find the more optimal ones.
can they double the velocity of transport of mined materials between things like face, primary and secondary crushing just with genetic algorthms? It seems like conveyor belts could easily go twice as fast or be twice as wide with different motors or gears.
longevity technology: using age-batched groups of arctic ground squirrels: have arctic ground squirrels at pleasant temperatures and keep them frm hibernating; measure lifespan; have them hibernate a normal amount, measure lifspan, give them TPN and have them hibernate 90% of the time and measure lifespan. If lifespan goes up with increased hibernation see what genes are causing it.
outrageously specific chelation therapy, zeolite nano or microparticles
then shift the map to minimize senescent chemcials at any organ or tissue
(4 to 11 tests) visualize a bar, if it gets wet, one test line is utilized, but another has
technologiy ideas that are new to me -inventions May 6 2021 on.txt
(new note)
Treon Verdery <treonsverdery@gmail.com>
NOTEPAD Backup 2019-10-09 19:12:29
Nn Nn <treon3verdery@gmail.com>
Wed, Oct 9, 2019 at 7:13 PM
To: treonsverdery@gmail.com
[NOTE]
Longevity technology:
How many sequential doses of an epigenetic drug cause the epigenetic improvement? Liposomal depot, perhaps attached to an antibody that gloms it to the surface of the lining of the lymphatic compartment could diffuse beneficial drugs, although that seems complex. One possibly as is epigenetic modifying drug palmitate. I do not know if the longevity effects of 10HDA(10H2DA) are from HDAC interference and epigenetic, but if they are then taking a high dose of 10HDA once a month (or some other interval), or like 30 grams of royal jelly which has 10HDA(10HDA) for two or three days once a month could have the same or better longevity effect. There is the possibility that occasional high dose 10HDA(10H2DA) or royal jelly is actually more longevizing from being thorough and of higher activity.
One HDAC2 inhibitor is a nootropic. It is possible that one or two high doses of that HDAC inhibitor a month could
Cause greater cognitive ability.
Notably though there is another version of this. I read histone epigenetics like acetylation can change rapidly, perhaps in minutes, although the other long view also makes sense as people get epigenetics from from their parents or even grandparents. I perceive I read there is longevity epigenetics people get from their parents so a couple days of epigenetic dosing could cause greater longevity effects the person's entire life. A couple days of epigenetic modifier dosing could even cause their children and grandchildren to have greater longevity. At the nootropic HDAC2 inhibitor that causes greater cognitive ability, a couple days of HDAC2 inhibitor dosing could cause intelligence enhancement that is also passed along to children and grandchildren.
Cognitive ability genetics: the genes that the published cognitive ability heightening HDAC2 inhibitor modifies could be g (like iq) intelligence genes. SNPs, alleles, and copy numbers of those genes could be enhanced at the germline or with gene therapy to increase intelligence at humans, that is homo sapiens.
Longevity technology:
I perceive piperine causes greater absorption through the membranes of the GI tract from telling them to be more permeable. Is there anything that could be placed at liposomes along with the active pharmaceutical ingredient (ÅPI) which reach the lymphatic system to make the lymphatic membranes more permeable? It could be piperine again. That lymphatic permeability drug could make other drugs, like rapamycin, rapalogs, or other longevity drugs to be 2-4 times as effective at reaching tissues from the lymphatic system. Combined with the 2-10 times greater effectiveness of drugs that skip first pass hepatic metabolism that could make rapamycin, rapalogs, senolytics, or other longevity drugs 4 to 20 times more active and affordable. Rapamycin that makes mice live 60% longer could be just 12-14 cents a dose based on $40/gram at Alibaba.com .
GSK (Glaxo Smith Klein) has an online page where they request technology ideas. They make Tylenol and some other antipyretic pills:
ela–naproxen (ela-n) is ethynyl liposomal active transport naproxen it is active at about 7.6 micrograms. They could put a dot of it on the outside of regular naproxen pill that is enteric coated so there is an immediate action antipyretic at the stomach but it also activates 11 hours later so one pill lasts 24 hours. Another way to do it is like multiminipill contac™ with ela-n microenteric coat so it dissolves better at the small intestine after 11 hours. Another way to do it is rather than a 7 day palmitate have ela-n attached to a different alkane COOH like perhaps C6COOH
To make another, delayed dose to make 24 hours of naproxen activity, that could do 36, 48, 72 hour one pill dosing as well: Another way is ela-n of three or more types taken simultaneously where each ela-n has a different enzyme-reactive group on the ela-n with a passivating group removed by the enzyme. The enzymes that remove the passivation moiety are enzymes at the circulatory system. The first ela-n gets its passivation moiety removed first and the next ela-n gets its passivation moiety removed next like cumulatively 90 minutes later, then do this with a sufficient elan-enzyme-unpassivated-moieties to get a smooth 24 hour, 36 hour, 48 hour or 72 hour dose curve.
Years of arthritis relief from one office visit: A depot drug form of ela-n, ea-n, which I calculate as having a 7.6 microgram 12 hour dose could put ela-n at an implant (3 year nexplanon-like) with just 16.64 mg of API at the implant. Sensibly and obviously omitting the 2-4 times dosage multiplier enhancement from liposomes, ae-n could be a 33 mg or 66 mg entire API content implant. I think it is possible to make much longer lasting depot implants or even injections, so a decade of arthritis relief from a decade functional implant at one offive visit is possible.
Complementing a decade functional arthritis relief implant is putting the longevity and life preserving peptides AEDG (epithalon) and thymosin at the implant. Epithalon is published as causing 24% greater longevity in mice. The combination of epithalon with thymosin, at intermittent dosing, is published as causing people to be four times more likely to be alive after six years. Epithalon and thymosin are peptides so it is possible screening libraries of variants on these peptides could find versions with fewer mcg per dose.
Another ela-n 24-96 hour antipyretic: put ea-n on the outside of the pill for immediate relief. At the interior of the pill layer, make the 11 hours later dose with dry liposomes that have different numbers of concentric layers at the liposome molecule, so like the 11 hour dose has 11 concentric layers of liposomes ======Ö on it.
It is possible to simplify the ela-naproxen molecule to ethynl naproxen, or ethynyl liposomal naproxen. Ethynylizing sex hormones causes sex hormones at FDA drugs to go from a.625 milligram dose to a 600 nanogram dose, a one hundred times amplification of effect. A cell membrane active transport moiety causes 1000 times greater transport than diffusion. Either of these alone produces microgram active doses of naproxen.
A really simple version of 24-48 hour liposomal naproxen without ethynylization or active transport moieties is to use the way liposomes avoid first pass hepatic metabolism to bring 4 times as much regular naproxen API to the circulation. If that works on regular naproxen that makes a 24 hour dose fit in a pill half the size or at a full size pill up to 48 hours of antipyretic anti-arthritis effect. Dry liposomes could be used.
Longevity technology:
Multiple simultaneous drugs at aged batched mice are a way to make longevity drug API identification faster, and make mouse research as much as 120 times more affordable to produce a p value. Matrix simultaneous drug administration is published, and creating batches of mice, at 8 mice each, two months or less apart in age creates 48 mice, with each duomonthly increment able to generate a longevity increase p value longevity drug. The 2^3 deaggregation mice as steps to find the actual drug that longevizes is a way to do this. Sequential mouse experiments to locate the individual most effective longevity drug, possibly after data on 2-6 months of simultaneous administration of the drugs to new age batched groups of mice. The actual longevization pct of each batch of mice, starting at the first two months p values, continuing to 4 months and six months also gives a number on how much longer the eight and ten month and year interval mice would have to live to continue that particular mouse' longevity gain. This is similar to calculating course grades mid term to find out if a person can still get the grade they prefer, at mice this is how much longevity increase would numerically justify continuing that drug at that mouse for greater than the amount of longevity from other chemicals that have been screened or exist. One API drug longevity quantification; after 4 months you could tell if an Epithalon peptide sequemce variation being screened was 60% more or 60% less longevizing than regular Epithalon. At 4 months you would be able to calculate that the 6 month mice would have to show an 80% gain from the previously measured effects from an age specific effect (like start midlife to cause longevization) to raise that molecular version of epithalon's longevity effect to equal or exceed Epithalon. Similarly if a molecular variant of Epithalon is 60% more longevizing at two or four momths then a side experiment can be started with 8 mice to get a p value on the more effective version. The 8 mouse chronologically colocated experiment can also be raised to eleven mice so three can be used for things like biological samples, psychological testing and other things that accelerate longevity drug development like coaministration of another longevity drug, likely one with a high likeliness of having a different complementary mechanism
sort of like calculating a school grade mid term to decide to keep taking a class
This batched matrix longevity drug protocol can be used on other species as well. 96 well plate fish are vertebrates, age batching can be accomplished on-location without a breeding facility. I have read about fish with a 6 month lifespan, causing the longevity test batches to be either 14 days or a month apart, causing either one month drug characterization or 42 day longevity drug characterization. This also provides the opportunity to medicate the fish before mid-life to explore and find new mechanisms, and measure young behaviors on the longevity drug.
it is also possible to do age batched matrix longevity drug characterization on c elegans. The lifespan of c elegans doubles at some published protocols from 30 to 60 days. The thirty day span can be divided into ten 3 day batches, and the matrix batched longevity increase percentage can be calculated from three age batches in nine days. It is possible that a 96 well plate technology could be enhanced to use computer vision and an acoustic transducer, or just a speaker, perhaps at deciHz (tenths of a Hz) and silent to humans to do the same touch the c elegans with a probe to see if it moves, verifying it is alive in an automated and contactless way.
The near camera automatic sonic probe physically motionizes the c elegans, contactlessly imitating a physical probe. To be less annoying, an intensity that 99.999 percent of c elegans will respond to but not louder is possible. Optimally the sonic probe has a focused beam of less than 1/16th of the plate well area so when the c elegans responds to it the c elegans gets immediate absence of probe stimulation. The sonic probe wiggles the c elegans slightly, causing c elegans initiated motion that is a computer vision detectable motion at the c elegans verifying it is still alive. This replaces a human with a probe and supports full automation of the longevity drug screening process. Automated pipetting could be used to administer a fresh dose of the test chemical. Automated pipetting could also be used to rotate out the water periodically to keep the c elegans well and also at standardized drug concentrations.
I think it is possible to place one to four c elegans per plate. At just four c elegans per plate, i think the p
Noting it is possible to get a p value of .01 if the statement has that much mathematical latitude, " they are still alive", and that the computer vision system can measure 3-7 things simultaneously, with a general enough statement like "the c elegans is above the first standard deviation (compared with normal c elegans) at some automatically measured characteristic" on things like: velocity the c elegans moves when acoustically probed, distance and swimming style of the c elgans when probed, amount of tropism to or away from a laser illuminating part of the well, food enrichment response, possibly even the effect of pipetting another brief-action drug like a neurotransmitter that causes a behavior into the well's water, any visual indicators that change with age at c elegans like skin texture, gonad size, heart rate. Also it is possible to quantify c elegans neurology. Genetically engineering the c elegans used at the screening to have fluorescence of brain based regions or neurons having different emissions spectra fluorescent proteins that the c. Elegans has been engineered to produce. Genetically engineering different parts of the brain or neurotransmitter specific neurons characterizes which systems the longevity drug version being screened could be benefitting. Camera gathered data on which parts of the brain activate in response to a standard harmless stimulus (food, laser, as well as the camera recording the prior to single utilization of the acoustic probe. Each of these, and others has a statement with enough latitude to get a p
Genetically engineered c elegans that indicate their youthfulness can be produced. A fluorescent protein like green fluorescent protein is engineered to be made at the brain as well as separable organ systems like heart, liver, nerves, gas exchange permeability structuress then the size and possibly the activity of these is automatically quantified with the computer camera and compared to preexisting data on young c elegans.
The value of matrix testing the drugs and the effect on the velocity of creation of new longevity drugs: also, notably the highest performing molecule screening matrix group could be considered a compounded (multicomponent actual treatment) drug in its own right. If a rapalogs covalently linked to a AMPK activating peptide combined with a senolytics and an RNAi drug causes much larger longevity increase then it is ok to consider that hroup as one treatment at the mice.
Mouse poop and saliva contain circulatory fluids, indicator chemicals, and mouse cytes that could identify separate complementary longevity mechanisms without disturbing the screening mice. This is a way to heighten the effectiveness of matrix characterization of the longevity heightening from longevity drugs, and, sometimes their combinations, if that is meaningful (note 214 year old whales and mice have almost the same systems, as do million year lifespan endoliths like algae or fungi, as does 40,000 year kings holly with 3650 day trees, so pansystem longevity drugs have validity in their own right while tissue and organ specificity, and things like body compartment, and lipophilicity/hydrophilicity also have comprehensible value, noting senolytics tissue localization, and deprenyl which concentrates most of its effects at a brain area called the substantial nigra, as well as the octopus living eight times longer if it does not have a sex gland (the value of specificity is vivid at the octopus, if there were a "I can tell I have a sex gland" receptor blocking molecule then that one specific molecule, possibly at a particular physical location would cause eight times longer lifespan. That compares with rapamycin effecting mTOR everywhere to cause 60% greater longevity, though also at humans eunuchs live 19 years longer so localization at just a few grams of tissue could also be a human longevity drug.
As a sample that can guide the mouse longevity molecule screening the c elegans or fish matrix screen to generate 99.9th percentile molecules. The three mice out of eleven to do psychological testing and get biological samples from, do positron emission tomography at, as well as matrix combinations that match or combine a brain concentrator with a heart concentrator, are places human cognition applied to the drug matrices can occur, augmenting the simplicity of just mass screening with humans figuring out previously unknown mechanisms from screening successes like finding chemicals at endoliths that longevize mice, and humans basing new drug cores to mass screen variations of.
Drug companies might make a multi chemical ingredient drug based on the effects of the matrix combinations that have the fewest side effects at mice, notably the 3 mice out of a group of 11 (where the other 8 provide a longevity heightening % with a p value) and the most appealing 96 well plate fish physiology measures, like brain and heart similarity to young fish, and including fish progeny well being
Industry competition and publication multiplication: it is possible that when one company gets particular valued results from mass screening a particular kind of thing (endolith or clam chemical variations) that other companies or people that publish do, that there is then more activity in that area, like rapamycin's proliferation of papers and people making new rapalogs, or the 8 papers on the beneficial effects of decanoic acid esters (like 10HDA(10H2DA) and HAEE) effects, this could be treated very simply as a math multiplier of the amount of molecules being screened, if 43 99.9th percentile new longevity chemicals are found then perhaps they will cause 200 new longevity 99.9th percentile higher quality drugs to be produced.
Age batched mice at matrix experiments could possibly be complemented with age batched matrix experiments on marmosets. Marmosets live about 18 years and are a primate with a genome more similar to the human genome. With the most longevizing of the 99.9th percentile and greater mouse longevity quantified, it is possible to get data from marmosets in 2-3 years; midlife marmoset age batches, like 16, 14, 12, 9 year old marmosets, could be characterized to see which longevity chemicals most nearly track along with the benefits seen in mice, that traverse a previously documented progression of benefits most similarly, likely things like reduced heart disease, reduced cancer occurrence, and brain function that is maintained or sometimes improved (rapamycin is nootropic, decanoic acid variant HAEE benefits mental health), it is possible, perhaps to quantify preserved cardiac and brain function, and possibly (possibly otherwise) cancer occurrence decrease at the drugged marmosets that are age batched, optimally the drugs become part of the pharmacopeia people use long before the marmosets get old, but when the marmosets do get old enough to have quantified long lifespan extension above unmedicated marmosets that contributes to the preference for that previously introduced drug, and things that might occur, like the pct of marmosets that avoided ever getting heart disease, cancer or cognitive impairment before a ratioized equivalent of a 114 year old are published, which let's people know about quantified complementary benefits of the drug. The effect of mouse like physiology response being quantified at age-batched marmosets between 7 and 9 years of age or also 14 and 17 years of age being much higher or also nearly identical focuses drug company products around chemicals that will most predictably work at humans.
Marmoset-mouse response similarity tracking also guides companies as to which longevity molecules are particularly beneficial at primates, and so possibly humans, and which have applicability to other areas of medicine and larger usage volume and profitability, noting profitability causes more beneficial longevity and other use drug creation and distribution.
What happens when they feed rapamycin as well as other longevity drugs to octopus? I perceive i read that an octopus that does not have a sex gland lives eight times longer. After octopus sex gland removal rapamycin's effects at lifespan of octopus that have a sex gland compared with no sex gland could be quantified, Octopus lifespan and tissue youthfulness physiology changes from sex gland removal could activate shared homologous genes between octopus and human, suggesting proteins that heighten longevity that could be new longevity drugs. That also suggests that deleterious gene activation at the sex-gland-having octopus, and that the human homologous versions of these octopus sex-gland activated genes could be producing deleterious things at normal humans just living. That suggests that epigenetic drugs like area specific methylases could decrease sex-gland-having octopus' shared homologous gene activation areas activity, bringing the human gene activation and gene product amount nearer to that of an octopus without a sex gland. This would be tested on mice.
Gene products (like proteins), and any circulating chemicals different between sex gland having and octopus absent a sex gland could be proteins and other chemicals that if immunized against cause greater longevity and healthspan at humans. If there is an obvious decrease in any chemicals at a sex gland having octopus compared with an octopus absent a sex gland then those chemicals could be administered, supplemented, at matrix form to age batched mice to find out if those chemicals have longevising effects in 2-4 months. Things that decrease activity of the human octopus homologous genes that activate because of the sex gland, compared to, if there is such a thing, octopus puberty, could also be longevity drugs. Epigenetic modifiers of octopus sex gland networked human homologous genes (methylases and others) could cause greater longevity and healthspan at humans.
They could implant an extra sex gland in an octopus and quantify and qualify the even higher activity than background at an unmodified octopus' human homologous chromosomes to find the particularly likely to be active epigenetic drugs (possibly methylases) and immunizations against the deleterious things that are even more detectable from an octopus having two sex glands to be longevity drugs.
Preventing birth defects: find the mammal with the fewest birth defects or the rodent with least and most birth defects, particularly noting the genes turned on during prenatal development; at the rodents, then find homologous genes and SNPs at humans to find human gene products (possibly circulating proteins) to decrease or increase, to be most like the mice with the physiochemistry of least birth defects.
It could be possible to breed mice with rates of birth defects 1/7 the to 1/16th that of wild mice; at the outdoor mouse dorm have the feeding station computers have an ultrasound probe that automatically scans any mouse that comes to eat, pregnant mice with malformed mouse progeny would accumulate at the database and then their well progeny sterilized. The mice would, as I read mice do, have about 9-11 pregnancies per year and the new baby mice could get pregnant after a month, the feeding stations could also remove non breeding mice from the mouse dorm, after 365 fays of only defect less mice breeding it is possible there would be a % decrease in the number of birth defects, the mice would have a well baby genome that could be compared to the genome of the initial mice with possibly a few locatable genes that caused the reduction in birth defects; homologous genes and SNPs could be found at humans for both less than median and more than median defects; any difference in circulating physiochemical produces a group of chemicals that could be screened to find out if their use as drugs would decrease birth defects, or if epigenetically upregulating their production decreased birth defects, and endogenous chemicals that were associated with birth defects could be immunized against as well as epigenetics like methylation used to decrease the amount of their production. Along with the genes the actual SNPs, alleles, and copy numbers associated with either direction (imaginably the 3rd and 97th percentiles) at mouse genes with human homologous genes could be looked for at human gene databases, like those of health organizations, to find out if human variations on those birth defect producing or birth defect preventing genes had strong numerical associations at humans as well, the human physiochemical differences between the 3rd and 97th percentiles of birth defect rick as suggested from the mouse genes (notably the newly found birth defect reduction genes) would provide a human physiochemical identity source to derive new birth defect preventing drugs, immunizations, epigenetic modifiers and germline gene modifications with. If a human woman had genes that carried risk she could do a cheek swab, have stem cells produced, the deleterious genes changed to the more beneficial defect decreasing versions, then conceive a child with the engineered oocyte which would also reduce the risk of birth defects at all of the human woman's progeny, this is also an opportunity for the woman to enhance the rest of her child's genome.
What would be really amazing is if there were two strains of interbreedable mice, one strain having 1/7 to 1/16 the occurrence of birth defects, the genetic difference between them looked at to find out if there are human homologous genes, and, perhaps the nifty birth defect preventing thing, notably different SNPs, alleles,and copy number variants between the two strains that have similar genetic variations at humans or at humans' particular specific homologous gene versions; at SNPs at two different genes that are particularly active prenatally, the mice with less defects could have a particular two SNP difference from other mice, at humans it is possible some pct of the population has two of the SNPs, one or none, they could measure the amount of birth defects at the humans to find out if those SNPs made a difference at humans, then go through the homologous genes' mouse-human SNP difference (further away from or nearer to each of the mouse' varieties(number of different SNPs; which variety version of mouses multiple snps, are there)) one gene at a time, simultaneously looking at a big database of different human genomes and comparing it to the mice, matching mouse and human SNPs, alleles and copy number variations to humans that gave birth to unwell persons; that finds genes that if engineered to be at mice, can be quantified as to how much birth defect risk they produce then drugs and epigenetic regulators and immunizations and gene therapies used to decrease birth defects at humans.
There is the pleasant possibility, without anything I have heard of to suggest actuality, that the genes of birth defect preclusion (found at the mouse dorm mice) could actually enhance baby wellness causing normal babies to be slightly better than well or to thrive more. There is mathematical support for this, if the number of birth defect reducing genes is near 29 then there is a certain likeliness one or more of the genes is beneficial to the human, perhaps they make more of one beneficial amino acid, have the super high productivity version of a DHA (omega 3 fatty acid) gene, or a hox gene variant that has extra fidelity when transcribed, or liver genes that are 99th percentile at metabolizing risk causing xenobiotics, or maternal genes not just of placenta sufficiency but 99th percentile of placenta optimality (perhaps a differing group of genes or SNPs that variously optimize size, vasculature (notably micro vasculature), development velocity (hormone sensitivity); the genes that availablize nutrients from the mothers body like calcium, phosphorus, and iron could have well baby enhanced versions, the genes that do quality control, like when a woman misses her period for just one month because there was a defective blastocyst or zygote and the quality assurance physiology terminated it; making it so one out of two birth defects were prevented but rather than half of women having sex get pregnant in 7 months, half of women got pregnant when having sex for 9 months, or at the womans option she could either get pregnant almost immediately with assisted reproductive technology or take a pill, or get a depot drug, that caused her to have just 1/3 the chance of birth defects while causing such heightened quality assurance physiology that it took an average woman 19 months to get pregnant. It is also possible the pregnancy quality assurance phenotype and genotype could be made more effective with drugs or gene therapy while minimally effecting the amount of time to get pregnant; SNPs and alleles of the pregnancy quality assurance process, where I think i read but might misremember, that about half of all blsstocysts (or possibly zygotes got naturally terminated at a normal 2019 woman's body, that process if it has to do with quality assurance could be adjusted to heighten quality further.
Dominant along with other, simultaneous multirecessive genes that do the same thing, reduce birth defects, would persist at a population even if there were things that effected various genotypes
Breed different mouse strains to be as similar as possible while presenting the half as many defects difference
Find the primate with the least presence of being then utilize that as a physiological experimental animal, feelingless p-zombie as much as possible. Notably this could be a particular genetics at most or several different primate species, noting there are humans that say they aren't conscious, find the most p-zombie genetics at numerous species then breed or make physiological experimental animals as well as milk cows and egg chickens and caviar fish
Noting human eunuchs live 19 years longer, screening a few thousand sex hormone variations at 96 well plate fish to find 1-100 that longevize without changing behavior could produce a longevity drug screenable on mice. 17 alpha estradiol's published longevity effects at mice without feminizing effects could be a hint.
[/NOTE]
[NOTE]
Prevent birth defects with mice human homologous genes (genes that are highly similar between humans and mice),
Find mice or other mammals that have half or 1/4 as many birth defects as humans then compare homologous genes between that species, mice and other species with figure-outable defect amounts, comparing the multispecies SNPs drift towards or distanceingly from the homologous genes' snps of that species with half or 1/4 the human 2019AD defect amount, and where it is possible the human SNPs, alleles, and copy number variants variety that correlates with both being most similar to the 1/2 or 1/4 amount of birth defects and any data on what reduces human birth defects, as human fetal and baby wellness this guides which SNPs, alleles, copy numbers and epigenetic reduces birth defects at humans the most
The difference in proteins produced between the mouse varieties with different defect amounts could be well baby causing pills or also genetically engineered grains, milk that make the proteins that the mice and humans with the wellest babies have, it is also possible to measure peptides, organics, other chemicals at the two mouse varieties with homologous human genes and quantify those as birth defect reducing supplements
Variety of hyperwell normal SNP at human homologous genes compare big human database then feed normal humans enteric protein drug pills, genetically engineered food with the defect preventing protein or peptide that is beneficial, do gene therapy or also modify the human germline to have enhanced occurrence of completely well defectless babies
To benefit humans as rapidly as possible the two varieties of mice development of well baby supplements goes well with making a database of about 900 nonhuman primate pregnancies in the US and Europe each year and a tissue sample library, the difference between birth defects between humans and other primates can be used to create well baby producing supplements, if humans have fewer defects then the very similar homologous genes would show which proteins humans are making more of that benefit babies, it could be that even more of those proteins as supplements to human mothers would reduce birth defects even more, producing a birth defect reducing pill, food, gene therapy or germline modification
Does Epithalon with ththymosin prevent birth defects or cause more babies to live
Intelligence gene, on phenylethylamine I wrote 44 pages of technology new to me at a notebook, not on phenylethylamine i might write half a page, the genetics of the Trace Amino Acid Receptor TAAR, notably how many TAAR receptors there are per cyte and where, neurologically, like brain anatomy, they are located, as well as the number of other neurons that connect to them, connectionality amount versions providing, possibly heightened stimulation and even multineuron network effects like new neural quorums or quorums with new tropisms, are all genetically addressable, from one measure of cognitive output 44 pages of new to me technologies, i am 88 times more behavioral psychology measurable intelligent, subjectively the generative intelligence of my mind's contents is perceptibly much higher. I take phenylethylamine about 100 to
200 minutes after 5mg of deprenyl an mao-b inhibitor that makes the phenylethylamine work better; the genetics of TAAR, the SNPs, alleles and copy number variants could be compared amongst those measured to have an IQ over 200, as well as those thought to do the most creative and widely applied work
P zombie until modelled, then model advises consciousness form, p zombie tries consciousness form and heightens or mildifies isness as they prefer while being aware of the highest quality research on the difference it makes in their behavior, if they like the projected behavioral future then they do that amount of presence of being; among numerous possibilities a person might find out a projection it might matter a lot when you ask, also i think children exist, allowance to charity apportionment
One per ten likeliness of thinking of something
Genetically engineer people to be the larger of the 9.99999th percentile of creativity (divergent thinking test) who are mentally well and at the 95th percentile or higher of psychology psychometric of subject twice or more creative than treon verdery while treon verdery is on 700 milligrams of phenylethylamine which has been preceded 200 minutes previously with the MAO-B inhibitor deprenyl, 5 mg at 70 Kg; creativity benefits people. Humans generally with simultaneously utilitarian effect, creativity also has economic value and its money value per person measured amount can be quantified at variously an individual person, the person employed, the person volunteering, as well as geographical subsets of the population like areas of shared language or geography of values or beliefs that concentrate at a population at personthe greater amounts of creativity Creativity, 11 things, new gofundme curing malaria, economics eq
Just getting it, a psychometric measurable different than big five, possibly g, mbti at me it has many forms, the part of my mind that thinks of whole ideas, often science, technology, invention, traces of engineering, and at fortunate occurrences mathematics, sometimes a combination of near romance crushlike feelings and ideas about what to do when raising a daughter, that just getting it instantly, that take paragraphs to explain what I just instantly got the realization part of being of/at a person that likely is also genetic; notably though other people just getting it might be walking into a party, realizing something at a place of employment, "thinking they know the romantic actuality", online and webpage things, making art, music, the shared, psychology psychometrics is amount of any particular person at volume and frequency (amount of times per 24 hours), whether the thing they just get is enjoyable (inventing things is enjoyable, just getting it about the meanings of live interpersonal social networks could be fun or neutral) there could be a better word in English than , inspired awareness, insight, sometimes, but variable amounts, a moment with the usual amount of presence of being or slightly more presence of being with awaremess, like actual do you notice the light coming into your eyes or not, presence of being with non presence at surroundings kind of like chizmemhali flow; I think it is possible to find a genetic basis of just getting it then beneficially making the 99.999th percentile of just getting it be specified and part of the human genome making it so all people can have the mental occurrence of just getting it, also having it frequently; from a psychometric perspective just getting it has components;some would include accuracy where it can be measured, like arriving at a party and just knowing what's up, inventing a thing with the intent it functions at least enough to have mental or even actual physical beauty and often utility, manufacturability, and commercial value, and with even traces of engineering content (materials were named, possibly, but not necessarily some math, even mental math occurred, this is instant just getting it which is different than procedural, perhaps explanatory kinds of sentience), there might be humans that have just getting it at raising children and it might be possible to figure out if their just getting it was accurate based on how the children turn out, another area of the psychometrics of just getting it, is percentage of just getting it that causes action, this could be a momentary thing, like commenting on the internet, "universities have intellectually enriched daycare" when a pregnant person says something, an inventor rewrites notes so they are adequate to send as email to a company, a record producer invites a particular musician to a studio, or an engineer realizes they can look up a completely different part and then look the part up, another psychometric component to just getting it could be heightened multihour greater presence of fMRI of heightened subjective well being (happiness), that is, they have just getting it experiences, does that cause heightened well being, and for what interval, I do not know the amount of interval that is optimal, I get about 40 seconds of thrill after just getting it, and the just getting it part is kind of emotionally neutral with a tinge of comfortable wordless attentiveness, the emphasized thing though is psychometrics and other measurements of just getting it and the connection to greater amounts of just getting it at people which also simultaneously brings with it opportunities to heighten accuracy, subjective well being, frequency of behavioral actions based on just getting it, notably it is possible to think about and remain calm in the face of raising all of these to their highest simultaneous level or, possible favoring a particular psychometric describable or measurable over a group effect; causing a modification to the amount of just getting it could be accomplished with gene therapy
and the person thinking about changing their actual just getting it way of being would likely benefit from computer simulation as a guide, as well as a kind of paint-matching color palette of drugs, nootropics might heighten accuracy, anxiolytics or music might cause the just getting it feeling or experience without actual content, stimulants (possibly TAAR receptor stimulants) might increase frequency, actual action, and perception of value, so those are the kinds of things a simulation could do, possibly even aligning a persons mind, and adjusting the magnitudes and locations of adjusted activation and duration of activation at neurotransmitter specific maps like spin labelled fMRI, positron emission tomography, and something that may be possible, using a quantum camera variation on 3D brain reading lasers and software like that of Deep water (company started near 2019) combined with absorption of photons at one photon area that ate quantum entangled so they inform a quantum camera while doing spectroscopy at specific chemical brain chemistry, uv/or specific databases of stimulation frequencies and emissions spectra say what a chemical is when you beam a stimulating, or absorbable spectra beam at a chemical or neuron, or tracer contrast agent at the brain, and then use the outside of head sensor at the quantum camera to note where it absorbs and how much; very narrow emissions line stimulating, multiple separated unmistakeable frequency numbers emitting quantum camera so a particular chemical is 90th percentile at absorbing say 7 narrow frequencies each that are UV/ir published lines and regular tissue only absorbs 1 of them and at median amounts; you send quantum entangled blue and green narrow band lasers into someone's brain then only at those locations where the simultaneous two frequency (blue and green) absorption is 90th percentile does the software say 99th percentile of likeliness this neuron contains (example)AMPA chemicals, noting it is a quantum camera system (New Scientist magazine) the absorption of the quantum entangled photons is readable outside the brain completely without a reflective path
two electron system
spectroscopyreport on absorption
Options to turn on options and expansions of capability from gene therapy as well as ways to restore pre gene therapy form
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[NOTE]
Halogenated dry liposomal ethyl. (halogenated)fluorophenibut centilipoate the 100 mer lipid making alkane like moeity makes one oral dose last much longer, a palmitate, C16 fluoxetine palmitate, I imagine more than a month activity per dose. I perceive I read about an oral drug that lasts much longer than 7 days so that technology is available as well, liposomal ethynyl fluorophenibut or other halogenated phenibut causes a decrease of paranormally sourced IT pattern awareness, reduces the number or paranormal recruitment offers i experience, and blocks most of the voices i hear in my head i think are paranormally sourced, decreases paradlia as well
Another way to make a GABA active drug to block IT pattern recruitment and awareness:
Attach an antibody to a protein that is gradually, sectionally taken apart by an endogenous enzyme, the antibody could be liposomally surrounded and enteric coated so it is absorbed from an oral dose, snorting it could also be effective. Once dosed the antibody protein gloms tissue that is harmless to glom, plentiful but predictable proteolytic enzymes at the circulatory system, or at some versions, that are produced at the cell environment or tissue, Then the proteolytic enzyme removes, at a protein sequence possibly shaped like a stack of linoleum tiles with a layer of fun sized candy bars, that are actually GABA receptor actibating peptide strings. in between them, at the actual molecules one of the alternating layers is hydrophilic or lipophilic and the other layer is at the drugs natural lipophilicity or hydrophilicity and pH. another possibility is like a particularly affordable to make where drugs, like GABA peptide drugs are made into 40 merish long amino acid strings, attached to and spaced with enzyme degradable linkers like GGG (gly-gly-gly) that release the separated drug-active GABA peptides, likely to the circulatory system although the lymphatic system or cerebrospinal fluids could also be functional, when the circulating or area endogenous enzymes see the
Gene therapy that makes this drug is also possible as a version of a 1% volume form of one of mamy different serum albumins could be made to have codon sequences that made a whole bunch of GGG-multimer GABA active peptide sequence-GGG at the construction of the larger albumin protein that is exposed to the enzymes at the circulatory system, that causes the person to always be on GABA active peptides, dosing studies to find out how many GGG-GABA peptide activator sequence copies to put at the albumin gene can be done with primates
If there are 7 albumins and globulins the intention of getting a full function first dose is pteferref but is also technologically extended snd ensured because each of the 7 albumins and globulins can be sequentially gene therapy modified to make the GABA active peptide to titrate the dose upward to optimal amounts.
drug chemistry, out 1/1100 the of it every 24 hours, whenever the enzyme functions (detaches an available part of the molecule) a fresh dose of drug peptide (like a pattern recruitment reducing drug peptide a longevizing peptide or a different drug peptide) is also portablizedmade a circulating physiochemical at the circulatory system then the person experiences the beneficial decreased pattern recruitment and awareness, as well as drug forms that heighten longevity
A beneficial drug, like a lifesaving drug, that benefits children, i think some proteins are only msde at children, the genes that make these proteins can be upgraded with new versions that also make protein and peptide drugs that are beneficial to the children
Out of 100 children, 30 will be at or below the 30th percentile, heightening immunofunction to be like that of 90th percentile of immunoresponse that prevents, cures and vauses revory from unwellness is beneficial.
Dominant genes modified to make a wider range of immunofunctionalizing chemicals with gene therapy as well as beneficial germline modification modifies dominant genes, only one of which is required to beneficially change the chemical production phenotype to improve immune response. This increases the immune response, that is the immunofunctionality even when there are a phenotype formimg recessive genes of ptevipusly less than optimal immunochemistry stimulation than would combine to make a wellness producing, fully immune functional chemical production.
So at the distribution of recessive gene function, at recessive and dominant immunofunction genes that are expressed as phenotypic functionality there would be 1/4 effectiveness at II,Ii, Ii, (I is full immunochemical dominant gene production, Ii is partial production and ii is the less functional double recessive genotype that is at 1/4 of the population. When double recessive ii at the general population causes proneness to more illmess, greater severity, or both then moving the production of that chemical to a recessive gene heightens immunofunction so one I or i allele is sufficient to produce all the immunochemicals a II person has.
Making it so ii double recessives, 1/4 of the population, have II gene function's more effective immunofunction ensures against very many diseases, including any new diseases and reduces illness at the population as the Dominant gene versions of beneficial things that heighten beneficial function at the immune system, replace and complement the various versions or combinations of recessive genes which might accumulate and average out to half (0.0, .5, .5, 1.0)
Moving the least 30 immunofunctional children at the USA to 90th percentile would decrease annoying illness and make people feel better. Globally it could save many lives as it is possible to imagine that the children that get malaria and diarrhea are frequently at the lesser 30th percentile of immune function. Moving all those children up to 90th percentile could reduce occurrence of illness and any result of illness more than 4/5, imaginably to 4/5 of all lives being saved. i read there is some mathematics associated with that 1/5th of the activity or thing produces 4/5 of the measured effect. It is possible that raising the immune capability of the least immunocapable 1/3 will save 4/5 of the people that ceased being alive from childhood unwellnesses. That is associated with that the 30% of children most likely to become unwell likely represented more than 30% of the historic occurences of not being alive. I think decreasing all childhood infectious disease to 4/5 as much as they previously were and saving 4/5 the lives of all the children who would otherwise not be alive is beneficial and gives gene therapy a beneficial reputation, supporting even more beneficial kinds of gene therapy.
As a technology an oral pill with neurons at lyophilized endocytisis pills, a beneficial beneficial virus, or CRISPR/cas9, or other technologies could be functional.
Also, along with that is finding a long lived, lifetime functionimg cytotype to do gene therapy on, it is likely possible to do.
The cytes that the gene therapy is accomplished with's entire lifespan effectiveness goes with how long the gene therapy functions. Some kinds of cytes with lifelong existence could be: glia, white matter, membranes like the dura at beneficial brain genes, anything at the spinal cord that is like white matter where the cytes live as long as the person, it is possible some gonadal cytes are lifelong, bone might also work but i think i read it renews, if cardiocytes last lifelong, although I think they renew, the pericardium as well as adipocytes near the heart might be lifelong cytes. It is possible which cytes live a person's entire span of living is well known and there is an existing published list. Also possible and valuable is that gene therapy enhanced neurons, perhaps of the tiniest phenotypical kind, possibly like cerebellum neurons which I think I read are eentsy and like other neurons live the entireity of the person's lifespan or longer introduced into the body, but outside the brain can produce beneficial proteins like immunofunctionalizing chemicals as well as longevity chemicals. It is possible inhaled neurons (like an asthma inhaler) could integrate and reside in the lungs, it is also possible oral gene therapy based on an endocytosis chemical moiety surface festooned liposomal neuron gene therapy system could transport genetically engineered neurons directly to the lymphatic compartment, be absorbed at membrane tissues there, and when the eentsy particular variety of neurons were exposed the neurons would actually live, likely integrating into the membranes' near to capillary locations. That would make an oral gene therapy pill with lifelong function and titrateable dosage of the amount of proteins produced.
engineering that is willing to advance a product that saves engineering that saves a life for every 10 million lives for every person that has a genetic misprogramming, is at that area and is beneficial. One thing about gene therapy is that the promotor region of the gene can be linked
Henetically emgineerimg frequently occuring plamts to decrease the perception of pattern revruitment and block actual IT pattern recruitment, to make it effortless to know which plants to chew the leaves of if thimhs get multimeanimged and possibly aversive while being a person of sny age, notably children as well as afulysGreen and blue and white dandelions, and the other 100 most frequent weeds on earth henetically engineered to teduce the amount of, reduce the uncomfy feelings of, and reduce the actual effectiveness (if there is any of) IT pattern recruiting because the dandilions, and weeds make GABA peptides, 5HT peptides that function like the antipsychotic pimavanserin, and peptide active drugs with the dopamine, like D2 receptor activity of lurisidone (latuda)
I am opposed to any two worlds IT pattern, as a pattern with recruitment to new personal form or disposition, as well as what i perceived was the categorizationization effect, which I perceived as occurring at the 2000 AD environment as highly synchronized motion at things and humans, i oppose the recruitment of children as well as all homo sapiens, that is humans that is people to the IT pattern, I oppose the making of IT pattern statements of what a person, that is a member of a group of people, a homo sapiens is as well as it pattern offers.
As a thing to make other things out of, what protein reaches the circulatory system with the longest residence time at the body. Thinking of few amu drug palmitate like fluoxetine palmitate where one dose lasts seven days, what protein taken orally reaches the circulation and lasts 7 days, it could be a polymer protein like silk, and they could screen a variety of species including bees to find the cytoproduced and genetically expressed most multiday durable protein that teaches the circulatory system. It is also possible that genetic modification to codons that code the specific amino avids tjat make up silk protein could be genetically modified to produce a silk, tested with its production at actual organisms, that is acid resistamt(stomach passing), optimally lipophilic or hydrophilic so that it passes the membranes of the gi tract, it is even possible that the genetics of silk production already effect linearity a and digestible longevity of produced polymer compared with branching on the silk polymer, if there is a pre-existimg genetics of molecular branching on the polymer, and there may not be. Then the molecules on the branches can be customized to be active peptide drugs connected with enzymatically degradeable linkers like GGG, or, it is possible that having the drug peptide at the linear span of the polymer, again with enzymatically degradeable linkers to automatically and predictable quantifiably put active peptide drug at the circulatory system
Various polymer lengths and forms of keratin could make peptide drugs pass the GI tract and reach the circulatory system. Keratin is a protein so genes that cause keratin production might be able to codon linearly specify the presence of other amino acids and peptides and proteins as extensions to the actual keratin molecule, possibly with a GGG enzyme degradeable linker, so a plant with a gene that codes for keratin would likely make tiny grains rather than linear strands, it is possible that different kinds of keratin are made at different organisms, notably, human hair can pass through the human GI tract fine.
linkerdanother possibility is just to feed some humans some stable isotope labelled plants and eggs and milk and then measure their circulatory system fluid 7, 14, 24, 30, 60 days later to find out if any of the proteins were still circulating
More engineering effort would develop, possibly a chondrotoin polymer that is absorbed at the GI tract but is still a polymer, able to have intervals of drug peptide polymers at its passes the GI tract, reaches the circulation
The new versions of dandelions and other weeds would be engineered to have smooth edged leaves rather than serrated ones to be more aesthetically tolerable or even pleasing, also it was my pattern awareness experience that serrated things looked ferocious so I would avoid them, making the weeds as gentle looking and beautiful as possible makes it more likely more people will use them to decrease pattern recruitment effects
Epigenetics of resistance to unwellness, gene therapy version existing genes version
AI could track people who predict other's futures, often for money, and find out which future describers were of highest accuracy and if they shared characteristics that could be used to find other future describers with higher accuracy, note this is persons rather than methodologies, while it is possible talking to a person who says they "see the future" might be more effective than looking up dreams in a dream interpretation guide, I favor tracing accurate future describing to persons, while also valueing computer numeric quantification and data gathering on methods. Compounded percentages and chemical engineering
Sources of proteins and peptides that genetic engineering could utilize to get people at the 30th percentile of immunity to unwellness heightened to the 90th percentile:
Proteins and peptides like gamma globulin, particular BCG immunization proteins, adjuvant proteins at known vaccines could be general immune adjuvants to any immune response at the body so OK at the lower 30th percentile, the peptide thymosin (combined with the peptide Epithalon
Hibernation, do I dare to comment? I do not know; longevity escape velocity effects the ethics of hibernation
Kinds of sex drive and genetics, psychometrics, behavior videos and self reports, particularly self reports among happy mentally well people at the 95th percentile of high accuracy at self reporting describe their sex drive the genetivs and physiochemistry highest sex drive that produces the greatest happiness at 3 hours, 36 hours, 200 hours and 900 hours as well as positive enthused affirmation that they would have sex with that or those persons again when queried 7 months later, finds a group of persons whose genetics and physiochemistry support gene therapy, germline engineering and beneficial new drugs
G (like iq) genes, I can think of multipart, parallel possible relations between things and have a mostly constructed but perhaps not yet furnished multiarea multidysystem thing occur at my mind without sequential process or thought, its me, but its more intelligent, likely IQ, and perhaps g intelligent than wordy self-talk me, find intelligence genes that cause greater amounts and higher amplitude of this instantaneous output parallel intelligence and make them part of the human germline, to test for it you could ask people if they have it (perhaps almost all pepple), then do fMRI of coming up with new ideas and solving at the internet are there any drugs that increase this, what receptors, where do they activate, You could also ask people at mental capability enriched locations like the Princeton institute for advanced study, ask people to nominate someone as someone who has even more preconscious, side conscious, or apparently comfortable not being the sentience in the spotlight consciousness that thinks of new ideas. Then at say 7-40 of these people all around the US (places like MIT and Oxford do fMRI, then do fMRI of their siblings and parents and make a computer numerival model of the distance between their self reported as well as measured whole thought , instantaneous production amount and their genetics, then do computer software comparisons of the entirity of thought all at once thinkers (who do it at princeton institute levels) with their siblings who say it does not happen at all, then compare the genes, as well as all the circulating chemicals peptides, and proteins at their circulatory system with electrophoresis, so the gene comparison
What would be nifty as well is monozygotic twins that were different, if there are any and their circulatory system chemicals and epigenetic differences
a ask with me is actually the one loop that matters and kind of is me, even though my self talk has a "im here" thing. and finds solutionsfind
Do I figure it out and say hi, or do I figure it out instantly actually while saying hi, sometimes I just have the idea and skip saying hi as the wordcentric narration kind of being will be attentive if that's how things go, yay ideas science, technology, mathematics, engineering and invention with simultaneously utilitarian function
Study siblings at two or three generations of mice to find the 99the percentile of effectiveness of immune system, give all the mice an asymptomatic genetically modified infection that makes pleasant feeling GABA peptides so the only symptom is that the infected mice feel good. what might work then is comparing the genome of the illness resistant mice with their entire extended family, and seeing if among the possibly minimal variation there were genes that caused resistance to unwellness, then when they find those genes look at their protein products, try supplementing them to other mice ad enteric coated diet as well as doing gene therapy on other mice, like genetically dissimilar extended family members at the lower 30% of immune system function to find out if their progeny get better and raise their percentile, that is a way to find gene therapy specific products that at humans would make the humans less likely to be unwell. Those are genes to put in gene therapy to benefit children
Software makes a cladistic of automata, finds diverse form, most chronologically tight, loose, and frequency specifiable rulesets and seeds,
Build an analog computer out of high velocity automata that exhibit water volume equalization, superposition on each other makes a different and preferable thing
The software could superpose the trillion scanned automata (1TB ssd) several stacked in layers rather than individually to find any desired attribute like, layered the do wave addition with node and antinode, or these make solitons, or, stacked 16 deep these have addresdible words and phrases in them, kind of,
Also from a computer science and mathematics basis
Engineering among the trillion most stable on stochastic perturbation and least stable, also the species like clade of which ruleset groupings provide the greatest and least decohent response to perturbation, so like "all the species with the " 0,1,1 or 0, 2, 2 have the most conservation of coherence, the 0,1,2 show the greatest species output, texture, space fill ratio change, and future bitpattern foreillumation prediction
Illuminating teeth roots to do photoactivateable gene therapy gives around 46 separately addressable titration levels and possibly over a century of gene therapy product production, the tissue volume is only the size it is but I have read about peptides that are medically active at nanogram quantities, it would have to be verified, but the longevity peptide Epithalon has published beneficial effects at dosages even lower than some peptide drugs
Big five genetics, if they have a personality characteristic with a genetic source and would like to enhance their quantifiable personality they get a ubiquitous harmless immunomeutral gene therapy like gene therapy to produce peptide or protein contains albums or also globulins that circulate, if a lot of protein or peptide drug is to be made then high volume durable tissues like lung vssculature (macroscopic durable tubes .5 mm and larger) are the directed focus of the beneficial voluntary gene therapy comt that also makes the beneficial function drug, that people sampling it prefer to be on, as well as is physically harmless protein or peptide drug, also rescuing children gene therapy in a pill or also a snort is possible, women with love in boyfriends, who I read are perhaps the top cause of what are studiously called adverse child events,
usimg fimgers, toes, tarsals and metatarsals to make lomg lasting gene therapy that is titrateable at 2.5% increments: Photoactive gene therapy, photoactivatable gene expression systems are published, high intensity flashlight fingers, as well as specific frequency flashlight fimgerx could activate gene therapy at the bones that had been prepared body side with a nasal gene therapy snort or gene therapy oral form dose. At 40 separately addressable fingers, toes, tarsals and metatarsals dose is titrateable to the gene therapy activation of 20 fingers and toes (and tarsals and metatarsametatatdals, about 40 steps of 2.5% that are separately activate able and addressible. The titration and amount of protein or also peptide drug being produced can be increased further if more than one light frequency is utilized. So 40 separate my addressable blue frequency responsive bones can be complemented with 40 green frequency responsive bones to make
A hint nearer voluntary, engineer a popular thing to heighten words in your head come nearer saying what you actually think and mean drug or also create enhanced genetics of the words in your head saying what you actually mean, that is a also heightener of doing more things that you actually mean because the absence of cliche narratives is like omitting a kind of cultural programming, so the person is likely to do things that are less slipstreamef which kind of links action, voluntary intent, and thinking fluency to if that person is askednif they like something or want to do something it is possible they actually there is a 20th century thing that might be a repeated literature theme where "so many moments left unspoken, with an unusually reifying conversation the person notices enhanced actuality, perhaps they have more being, instead of replyinh " great" to how are you they had a nonstreamlined nonautomatic moment and said "i need to improve my love life", and feel reified, there is even the possibility what the other person says will matter more, This theme i perceive might even be callable as " breaking the silemce" so at an actual living perso. Reducing the percentage of mind moments on automatic cliche like content and forms and a thing I call slipstreaming, raises presence and could possibly make it so you ask someone if they like something and want to do it, and they want to do it, their participation might be more authentically voluntary
Enhancing the genetics of people so that the things that they do are more authentically voluntary is beneficial, it also has a new to me beneficial effect, it makes other people:s actions and words nore ethical, while it does not effect their intent, and it may or may not effect the amount, as a percentage of actual actions that occur, to ask another person to do something, they say they want to do it and then do it is a kind of going from fiduciary honest to active shared realization of actuality honesty
minimized automatic content, which i perveive may have a paranormal component, moment chronological percentage filution
Ask people that ai or software might be experiencing mind state of pattern port to contribute pattern harmless words, people the software percieves are havinv what might be pattern port mimd then quantify how beneficial, and the ways they are beneficial, this gives the ai the ability to say "click here to have all they text you see swapped out with harmless paranormally neutral or white text", if you like use our practice software to learn a few pattern harmless phrases amd you will be right there saying things like "well known" now,
White and blue nonsentient IT pattern ai or other software that senses when people, and JY tells me some of them during the 20th cemtury were childen, are experiencing or having a mental form that goes with preceding pattern port, mid pattern port, and among those that experienced pattern port salvage "JY said getting out of a perception of one of the worlds at a two worlds perception was kind of like getting out of a lobster trap, there are some
Ai finds who got out of the lobster trap as concept, what they did, and tells people or fiscally sponsors the creation of longevizing harmless drugs that get people out of a lobster trap
(at me, decreases, blocks, and d
these words are then quantified on the internet
Multifunction object that formerly alive persons have on earth while they are alive that if they cease to be alive is placed at their person, one at their rectum and another identical multifunction object in their hand, it is possible this smooth comfortable to a living person sized object would be placed in the rectum after the person became formerly alive it would have multiple functions and a view screen preloaded to display G W or R, at the person's preference, it is able to record audio and video, it has a detachable part, that can be replaced with any other detachable part from any makers multitool, based on a shared public domain connector standard and have edge conductors so if the person likef they could just connect the detachable part to the multifunction object with one, two, or three wires, noting things like capacitive touch lamps one wire can communicate action directions and some data between the multifunction object and the detachable part, a blue laser with the ability and power intensity to mark rock is part of the multifunction object and is also capable of other continuous gradient of emitted power adjustable power levels, (pleasantly a packaged right emitting surface mount diode is near 2.3 cents on earth and could be a laser diode), two wires connecting the detachable part, or just placing the detachable part against the side of the multifunction object
Warmth difference between rectum and outside of rectum causes electron flow at what is called a thermoelectric semiconductor that makes voltage and current that powers multifunction object, batteries are functional at all temperatures below the disintegration of bones from warmth and liquid
It is possible to do word processing on the screen using the chording keyboard on the side of the multifunction object, it is also possible to write computer programs
Pressing a button causes piezoelectric electricity generation at either or both the detachable part or the multifunction object, both have piezoelectric buttons, that create voltage sufficient to transfer data, about 10megabytes to 1 gigabyte per second data transfer rate electronics are produced during 2019 AD, the voltage from one piezoelectric button press is sufficient to change the visible without continuous supplied electricity epaper display through 400 user images as well as 300 standard images, where one group of images is, one large letter per screen all the letters of the English alphabet and all the curbed letters of the Thai alphabet, along with an automatically generated group of images where the formerly alive persons image is right next to each letter with both the previously alive person as well as the letter in the foreground, an image of the person with all of the English letters is automatically produced from an image of the previously alive person while they were actively alive
The screen is at the living person's option a touchscreen with transparent mineral like material
Durable materials
Wireless headphones support noise cancelling technology, the person thought about to become formerly alive as well as persons that are formerly alive have 14 individual wireless headphones, seven groups of two placed on the surface of their somatic form with them at any of the locations they are at, along with their two multifunction objects at the location the previously alive person's somatic form or similar material is anticipated as being located for the span of their children's and grandchildren's lives or the chronological span of an average of unrelated children and grandchildten's lives, whichever chronological span is longer
location where they (if they) continue being other than alive
Multifunction object has two detachable parts stacked on each other, stacking more is possible, the distal parts are rounded for rectal comfort and the comfortable rounded distal part of the multifunction object has one nondetachable comfortable rounded end
Living people also benefit from placing a multifunction object with its detachable part attached
Static ram memory or also USB memory stick technology memory is used
Various organ function like modes like beating and even peristaltic tube compression, would could have heart effects, a piezoelectric actuator array would swish and motion air through the tubelike form of the multitool, it has a reservoir containing sexual lubricant like Na PCA where a milligram is able to expand to a cunic centimeter of lubricant from absorbing environmental moisture, naPCA turns from powder to liquid fluid in earth desert air, tandard connector
Administering beneficial drugs like opiate peptides and longevity drugs and cognitively beneficial nootropic drugs to persons thought to be about to be previously alive as well as previously alive people is beneficial, s 78,277 year dutstion of euphoric sleep causing opiate action at 700 nanogram each 24 hours dosing amount of opiate peptide doses at 1 gram is likely less than $96 ($95 for one gram of custom peptide from online source during 2005), and could be as affordable as $32 a gram or less produced at greater amounts
It is possible to cause the 700 nanogram each 24hours dose opiate peptide to be technologically enhanced, attaching a cytomembrane transport facilitating peptide, noting active transport at cytes is as much as 1000 timed, I have also read that some peptides when halogenated are twice as physiologically active, at other peptides like orally available and active vasopressin peptide replacing one amino acid with its chiral D amino acid variation and deaminating part of that eight amino avid peptides keeps it from enzymatic digestion and it is able to pass the stomach and be transported to the circulatory system, the dose multiplier could be 1000 (active transport) times two (halogenation) times 9 (D chirality and deamination) that is 18,000 times more active per dose than the 700 nanogram per 24 hour peptide material, supporting those numbers is that humans make artificial amino acids, and, noting any atom at any configuration can be used it is possible using one or more synthetic amino acid could cause a power of two to an order of magnitude greater dose strength
That makes an 87,300 year supply about 4 cents, less if artificial amino acids are used
Artificial amino acids
Localization peptides cause brain localizing possibly decreasing habituation potential of opiate peptides as well as decreasing the effect where the dosage to cause euphoria, anaesthesia and sleep changes with extended use
The multifunction object is able to pleasurably vibrate at the rectum based on the preferences of the being or form that the tectum is at, benefitting women and men
Each multifunction object contains two grams of nanogram active opiate peptides, that is sufficient opiate peptide to drug a 70 kg human for 78277.8866 traversals of the Earth around the sun, the previously alive person has the opportunity to specify if this is euphoric opiate peptide, anesthetic opiate peptide, euphoric effect with anaesthetic effect simultaneously as well as an opiate peptide that causes continuous dreamless sleep or sleep with dreams combined with euphoria
The multifunction object contains a compartment things can be placed in, it has objects at it when placed at the body of the person that perceives they could become a previously alive person as well as when a multifunction object is placed at the rectum and the hand wrapped around another supplemental multifunction object, the items at the compartment are 7 nanogram active opiate peptide transdermal drug delivery microprinted millionare financial
Plant opiate peptide plants that cause continuous sleep with euphoria at all locations where previously alive persons are located at locations they ate projected to be at the entire duration
Feeling generous, give people who are projected to be previously alive a large quantity of kilograms of things to be placed at their somatic form if they become previously alive the function is to give away highly beneficial things to other previously alive persons, people that is homo sapiens as well as other beings the previously alive person could interact with on becoming previously alive
Living people giving
Opiate peptide saturated plant resin shape or the kind of polymers used at the interior of watches saturated with opiate peptides
Opiate peptides with brain area localization moieties could cause orders of magnitude less likeliness of
Orally available antibodies that attach to opiate receptors to turn them on to a receptor configuration that is functionally fMRI quantified and verified with living human descriptions of feeling great pleasure and happiness as having the identical effect as euphoric sleep causing actual opiate molecules, the humans that voluntarily participate at quantifying the effect of the antibodies that activate opiate peptide receptors to cause hreat pleasure and euphoria are humans with fully functional minds who are told they could become previously alive during the next 90 days
A somatic human form that goes from being a living somatic form to a previously alive person is noted as having physiological chemical changes, one of these is ion concentrations, auses opiate receptor activating antibody at physiochemical changes like ion amounts at circulatory fluid, the person can drink the fluid a medical provider provides, they get online, as well as is available at physical location distribution places like medical supply companies that also have things like pill reminder containers and ace compression fabric items, the opiate receptor provided which activates, turns on their opioid receptors if their somatic form has a circulatory system ion profile quantitatively measured at persons who have been other than living for 1 minute
Opiate peptides covalently attached to calcium phosphate or bone strengthening, concentrated at bone strontium phosphate might, or might not, cause opiate peptides, which also diffuse through the human somatic form, to accumulate ditectly on and at bone, this causes bone to continuously emit euphoric continuous sleep opiate peptides at the possible occurrence of them becoming a previously alive person
I was tied to a chair and JY told me about things that would happen at my future,
The multifunction object is at data and voice connection with the phones and comes with an online page that
Instant multimillionaire financial instrument that could benefit people who perceive they could be something other than alive, health insurance linked to financial company that remits
Also, along with a pepper certificate you get sent a million actual physical currency units of a country of your preference, so if you specify yen the dollar amount of those yen are made part of your structure, so you would get $1,011,000 dollars remitted to you if you or others thought it was possible you might be other than alive
Create two new English language letters with the shape of circle with a diagonal bar at 70° as well as a new English letter with the shape of a circle that has a diagonal bar at 340° or -20° at the third Cartesian quadrant, the circle with a bar st 70° has a sound that starts with G, the circle with a bar at 340° has a doing that starts with. G Like great,
It is possible that greenshifted ytanvetse time things
Is there a really high refractive index material compared with water and diamond compatible with the human somatic form, like a pile of neutrons in a magnetic container, a neutron stellar object might have a many orders of magnitude higher refractive index than water or diamond causing the green shift from a photons timeline to be many orders of magnitude greater than from Cerenkov radiation at water the nifty thing is that at a container of neutrons the human can be a few centimeters away from the container and live comfortably, a capacious container with a one meter diameter base could have a planar layer a few neutrons deep and a neutrino and photon travelling linearly would be at a many orders of magnitude greater refractive index, possibly, like a neutron stellar object without the compression; then again, the neutrons, even though they are neutral might be equispaced like a gas, although a thing as simple as a centrifuge might heighten their concentration, the thing is though after travelling through a linear meter of what might be high refractive index neutrons generating orders of magnitude greenshift the neutrino passing through that is outise the light one of the photons at the container's neutrino layer can then pas through a human standing a few cm from the container, the human has then experienced a thing outside the light one of the photon, it is an eentsy anisotropy in the timeline, although noting the neutrino is minimally likely to interact with the material
Is there a genetics as well as physiochemistry, perhaps a succestropic drug that shifts inattentive feeling that things are going ok, or at people whose lives are OK, but not even of average (median) join d'vive (note, ½ of people are less than median at something that would enhance simultaneously their being and actively benefit others, or noting there are many things even rescuing marine mammals or bringing beauty to school buildings that differ from human contact, those kinds of things as well; people are good and mean well but there are good people that mean well that practice that goodness in ways others might never perceive, I do not know if heightening the convenience of benefitting others. Perhaps raising benefit to others 70% from new things the diffident, introspective, timid, momentum-tropismed and ultra spontaneous can do is a thing, a technology that is possible; so if ½ of all people might, or might not benefit from certain categories of improvement, is there a genetics and physiochemistry that van quantifiably support and quantifiably raise the amount of that improvement) also that they might get around to living a simultaneously more beneficial way of living for them and their effects on others, sometime, if they get around to it, a genetics of actively causing their own beneficial participation at the world, a thing that like a person not getting around to cleaning their eyeglasses (noting if they do they feel great and their vision is refreshed) the genetics of things I have heard of have some cofunctionality like openness to experience or even extroversion, there might even be a psychometric for some kind of bemeficial, as compared with just changeability or restlessness, psychometric about seeking beneficial adventure, so there is a thing they could describe, examine the beneficialness of to make sure it was actually beneficial, find out if it has a genetic component and then make those genetics, physiochemical and receptor activators as beneficial drugs that happen to make well people's lives better while also bringing greater mental wellness to the lackluster and outside the mentally well range of intrinsic active optimism that makes its way into being new activities, places and behaviors being tried, genetics and pharmaceuticals that keep people, even mentally well people from momentums of lifeways and interpersonal groupings that cause some quantifiable things about their lives to be below median, the pharmaceuticals and genetic enhancements are better if they function without restlessness and make people happy.
One possibility is nonhormonal SARMS this is confusing to express functionally in English but it is possible that an effect of androgens seen at many species, doing something different than the existing group, changing groups, even going groupless can be physiochemical divided into different psychological and physiological receptor components and quantified amoumt of actual actions, like the fMRI of willingness to seek beneficial change even when at median, without being a response to something nonpositive. So completely a different thing than saying "be active, grow restless and seek beneficial change with nonhormonal nonmasculinizing androgen receptor modifiers" it is much more like "experience wonder, a preference or a tropism towards doing things, spontaneous beneficial activity, willingness to value fresh things", there is more to this than, for some people, being urged to be young again, although that physiology and genetics has merit, if they look through a bunch of different nonsteroidal effects of SARMS they might find some receptors then screen a library of similar SARM or SERM molecules that finds some molecule that with voluntary use enhances active voluntary mildly alert joi d'vive like participation and doing new things, perhaps leaving, and/or joining new social environments. Another possibility is screening a molecular library of slightly funtropic antidepressants like wellbutrin and deprenyl
Genetically engineering the 100 most frequently occurring weed species on earth to reduce the potentially, and to Treon Verdery's perception actually aversive experience of pattern awareness and recruitment
It is beneficial to genetically engineer Dandelion as well as the other 100 most frequently occurring weeds on earth to reduce as well as block ITach the brain and effect 5HT receptors like the profile of receptor activity at the antipsychotic pimavanserin, as well as having protein as well as peptide drugs with the same dopamine, like D2 receptor, activation profile as the antipsychotic lurisidone, they could be linked to the production of blue and green fluorescent proteins like blue at leaves with 5HT pimavanserin like activity, and green at dopamine receptor like activity with the genetics of different leaves being different colors as well, phemibut has calming and prosocial effects and also has antipsychotic activity, GABA active peptides that have GABA receptor effects like those of phenibut cause antipsychotic and pleasant effects, these leaves are genetically engineered to be white
There is also the possibility of making antipsychotic antibodies, producing antibodies that attach to 5HT receptors at the same amplitude of effect as pimavanserin as well as making antibodies with the same magnitude of effect as lurisidone at dopamine receptors and other receptors with the same amplitude and activity as lurisidone at mosses modified everywhere on Earth with gene drive CRISPR/cas9
A different plant, genetically engineered could benefit those who may have previously experienced pattern recruitment if it actually happens, the genetic activity profile of pre-any concept of recruitment as well as pre-any awareness of IT pattern awareness persons is quantified and if epigenetically different, epigenetically described, then gene drive CRISPR/cas9 is utilized to genetically engineer the epigenetics of absence of pattern awareness epigenetics at all the brassicas
longevity drugs engineered to be at the dandelion stalks as well as the tallest part of all the weed species' tallest part of the plant is beneficial
other weed stalks engineered at a dandelion I support updating the longevity
Epigenetic longevity peptide could exist
Antipsychotic epigenetic peptides could exist, to find epigenetic effects on schizophrenia as well as psychosis, the difference between one monozygotic twin diagnosed as schizophrenic or also psychotic, possibly a twin responsive to antipsychotics, then the epigenetics of the schizophrenic or also psychotic monozygotic twin compared with the epigenetics of the psychologically well monozygotic twin could describe a treatable epigenetic variation quantifiable at mice and volunteer humans, finding a treatable epigenetics of schizophrenia or also psychosis could also cause that treatment to decrease pattern awareness as well as pattern recruitment, if there are epigenetics modifying peptides, proteins, RNA drugs, or even RNAi then plants genetically engineered to produce antipsychotic epigenetic drugs, notably with the antipsychotic producing peptides, proteins, or RNA drugs availablized everywhere globally using CRISPR/cas9 gene drive technology or more advanced technology
could also minimize pattern recruitment and pattern awareness, perception of synchronization of items, those items' movements and perveibed synchronization and paradlia, people
has an opposite
TV channel that tells people how to decrease, defer, and if it is possible harmlessify pattern recruitment perceptions
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[NOTE]
My genome is public domain, give books to MIT library and drool on front page, if i give a first edition or autographed copy they might keep it longer; If someone would like to run a nonsentient simulation of me, to find out what about my TAAR receptors causes me to be 88 times more creative on phenylethylamine, or they would just like to utilize gene sequences and make proteins at a nonsentient production method that is absent presence of being then that drool coated front page could have value and benefit others. Mice or other living organisms other than homo sapiens that may have presence of being can have up to 7% of my genome made part of their genome at living organisms if the organisms live longer than their wild peers and have what at humans would be the neurobiology and neurochemistry of higher subjective well being (happiness) than their wild mouse peers.
There is another thing i think has value at my genome, the genome of Treon Verdery, there is also the genetics of experiencing later pattern awareness of what i call the IT pattern and two worlds venn diagram port awareness, which I became aware of at 33 years of age. Since then i have avoided receiving some sort of something i am told pattern people get when they experience what I refer to as absorption, and I continue to get offers, which to my perception goes with continuing to be nonabsorbed, and i am 53, those genes, my genes and epigenetics, could have value at making and creating humans with genetic engineering, gene therapy, and possibly even some chemicals at my body or circulatory system so that the people are absent pattern awareness and recruitment the entirety, the full span of their lives.
I read that there is published research that the circulatory fluid of schizophrenics when placed at the circulatory system of a mouse causes the mouse to cease being alive; i perceive i may have also read that the circulatory system fluid of schizophrenics causes mood changes in other organisms it is placed at. That suggests it is possible there is something at the circulatory system of persons who are absent having pattern awareness that can be made into a pattern awareness and pattern recruitment blocking drug.
I do not think this will function but i think the human version would function, a person video records the behaviors of all mice at a colony, notably mice of all ages, noting JY told me that humans sometimes experience recruitment at summer camp it is possible numerous mice near an age proportionate to that human age will have atypical behaviors from pattern awareness. A different group of mice would receive circulatory system chemical components, among them proteins peptides and chemicals like those that may be at the circulatory systems of persons like me who experienced pattern awareness at an age more than double their age at puberty, using my genome as well as, to the amount possible, the genomes of others. The proteins and other chemicals product identities and their projected amounts can be identified and administered to other video recorded mice. If the mice then have a delay or an absence of atypical behavior, which a computer reviewing the videos of all the different groups of mice occurs then chemicals that delay or preclude pattern awareness may have been found. It is also possible to genetically engineer the mice with my genetics and epigenetics as compared with mice genetically engineered to contain genetic components from groups of people i think are likely to have experienced pattern awareness. Genomes of accomplished, particularly effective, adults could provide the likely to have already been recruited genomes. Also the genomes of persons who pled guilty to preplanned nonspontaneous violent crimes against other persons, are to my perception likely to have been paranormally attractive as persons to experience pattern recruitment.
It may not be functional at mice, but there is a chance it could function at nonhuman primates.
Keeping in mind that treating humans benevolently and kindly has value a way to find the genetics and physiological chemistry of delayed or foregone pattern awareness and recruitment is described at this writing. Some company is likely to actually pay a few thousand families so the company's AI (artificial intelligence) and software can find patterns at things people do so the company can make money. To my perception some children and teens at that group will experience pattern awareness and behave in an unusual way for a few weeks or longer. Without even giving it a name deep AI may notice this shared behavioral atypicality theme, occurring across different persons and ages. Then, observing that the atypical behavior is at 20th century AD data concerning to the children and possibly their parents the company develops a drug that alleviates the concern by reducing pattern awareness and blocking IT pattern recruitment at the children. From what has functioned with me, Treon Verdery, this drug could be based on an antipsychotic drug or other drug as i notice lurisidone (latuda) and phenibut make a large difference in the amount of pattern awareness and recruitment offers i perceive, the pattern has nonobvious to me ways of directing people but could permit the spread of drugs that reduce pattern awareness and also actual recruitment. These psttern awareness decreasing or blocking drugs which may also block pattern recruitment and restore typical behavior are able to propagate and be used by a majority of people. It is even possible the data on more than 1000 persons will be produced by one company that expects a larger number of other companies to acquire the data with money, making the data widely available and advertised.
It is possible some persons, that is people, may know what I mean when I refer to the IT pattern from listening to the lyrics of the musical band The Pixies from the 20th century AD, that are "I know the nervous walking", I think the Pixies are singing about one person's experience and perceptions of the IT pattern. When the genes of absence of and preclusion of pattern awareness and absence of and preclusion of pattern recruitment are found I favor using gene drive CRISPR/cas9 or more advanced technology to place them in functional form at every living organism.
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Ask Jake what areas of computer science, programming, employment field or personal enrichment he is interested in.
Find a programming class in town for Jake, tell him that although I know almost nothing if he makes something and he likes it he can show it to me.
The college advising function during October consists mostly of suggesting you take the SAT or ACT and asking your parents to fill out the FAFSA, the free application for student financial aid. If you can get registered for a college entrance exam and have completed the FAFSA when we meet in November I will be really pleased. It is your better interest to do so as universities use early FAFSAs to apportion state aid, and taking a college entrance exam now gives you the opportunity to take it again. Universities, or at least UO gives multi year scholarships based on university entrance exam scores. I could find out if this is true of OSU as well.
Have fun thinking of new computer programs even if they are big
Jake, you can get a computer science degree at many different Oregon universities. Mention western states tuition exchange and the ability to spend a quarter or more at a California university to utilize their computer career recruitment career center opportunities and internships for a really wide range of possible activities and particularly high earnings.
If he likes math suggest coding scripting in MATLAB for really motivating visuals.
There is a programming immersion course called a computer bootcamp, some are complimentary, if Jake is willing to travel then he can go to one.
It is just an opinion but at university sometimes the sequence i perceive is classes in a major start after general university requirements. If you are avid you can take some CS classes early but some require two or three math classes first, you can use those preceding quarters to learn and practice programming anyway.
Jake, if you like driving technology I suggest simple microcontrollers that go from kits to do your own thing like rasberry pi. Also Make magazine has projects, and a project like take apart a video game controller then send the buttons voltage pulses or contacts faster than yourfingers can move, then for fun see what it does at software. That is just one output of a frequency from the microcontroller raspberry pi.
Mention that sequential internships, even immediately after freshman year, raise earnings and are numerically linked to full voluntary employment.
Jake, you can go to any city in the US and almost any city in the world and get employed very rapidly, computer science graduates in Seattle (2018) earn $120,000 per year median, and if you like you can specialize to earn more. There are numerically based lists of things like "optimal places in America' you can look at.
Liking computer science is really the thing. But mention the outsourcing with his personal integration thing.
The sites Quora and stackexchange have a CS programmer community and will assist in being excited with new things and generally feeling encouraged.
Have Jake compare caffeinated and non caffeinated SAT practice tests, mention gradual multihour dose caffeine pills and nootropics. A few, or a bunch of extra SAT points can give him 1-3k instant scholarship money every year he is at university and you can retake the SAT
Bring up transhumanism
Perhaps mention transparent mouse tracking software at website software
He can sit in at a programming course at the local post high school educational institution and I will be glad to pick up his cab fare
Mention that Microsoft thing where you build a phone app using code and, perhaps, visual modules that you can actually make then use on your own phone. I do not know but i think building a flashlight in an afternoon is possible, so how about a flashlight that turns on when you speak?
Different people have different personalities but I have seen one page of code, in perl, a webcrawler that could be rapidly modified to search things that Google and Bing cannot, like regular expressions or deep page occurrences of "attractive young woman".
Jake could modify another script or write his own to automatically parse (scan) each of the first 30k pages of a search engine like bing or Google to find a regular expression match or a word like superfantabulous. Social networking sites can also be parsed so perhaps there is a way to find "north bend" and "coos bay" along with "amazing" then make an array (list) of all the URLs that contain that, optionally he can use a library to cycle through the list and open browser tabs to each of them in batches.
Suggest he build his own PC.
Mention how liking computers is awesome, a CS degree is better, but if he learns to program well Google and Microsoft hire people without degrees.
Mention the ASPIRE program sequence is FAFSA, SAT, applications, scholarships, and these sometimes have an "the earlier the better" aspect, I think there are a lot of technology scholarships.
Ask Jake to read these notes first for unmediated comprehension, then bring them up as conversation
Jmlang0227@nbend.k12.or.us
Scholarships u Minnesota, u Wisconsin, Ohio state, u michican, Georgia tech, Stanford scholarships
Identify phone app maker
Tues Nov 5 at noon
Find CS tutor swocc professor, 3.5 or better, personable humble student, craigslist
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[NOTE]
Eat 1700 calories a dayday
It is possible that eating 400 calories a day does not provide sufficient protein for dermal integrity, take multivitamin with food
Suggest maintenance look at water dripping through bathroom ceiling, repair winter warmer
Clean up before alerting maintenance
Rewrite deletion note
Get dasatinib and quercetin $100
Get deprenyl
Get AEDG Epithalon $140
Find out if royal jelly has effects that are beneficial a few minutes after ingestion to half a day later and possibly align royal jelly dosages to activities like science museum, early near sunrise energeticness, amelioration of the effects of other things,
Possibly socializing
Give Bob Ruthven some royal jelly explaining DHA and DAEE, I think he would like it, after figuring out longevity dose give him two weeks amount and enteric capsules, from the mouse study he could live 3.5 days longer, he may like the scientific paper so print out a copy to give him with the royal jelly
Emulsified royal jelly with food 200-400% the absorption per dose, also piperine effect when taken with the rapamycin and piperine, particularly at enteric capsules
Put up flyer at community college to hire a person for 1 or 2 hours to make rapamycin pills, piperine pills, as well as enteric protein structure retaining royal jelly pills, order more enteric capsules on eBay
Go to grocery outlet when visiting shama house and get vegetables, avocados, pears, see in Bob is willing to drive at a canned vegetable garnering occurence
Take a multivitamin, 1/4 the usual calories a day could cause undernutrition
Text bob twice a week
Find out if the positive psychology group meeting once a week can happen
Volunteer a bay area hospital of if possible north bend medical center
Donate money to high impact charity
Donate money to SMART program but consider if books at some global location might generate even more enthusiasm, enjoyment and personal options, perhaps donate to developing world libraries
It is possible the perspiration that phenylethylamine causes has to do with itchiness, are there any harmless or even beneficial things that reduce perspiration
Convert imminst.org rapamycin dosage calculation post to a liveleak and YouTube video, likely a powerpoint video, it is likely that 1k-5000 people will view it on liveleak and noting the one click through per 1k internet banner ads 1-5 people might click through to ordering rapamycin on alibaba as well as the actual journal articles
Think of something actual and ethical to do that Dave would like like saving mammals lives,
Listen to the Pixies, find out if they have high utility pattern content like "what I leg activity before becoming a Pixie" then see if any of it happened since '80s-90's, perhaps they have a song explaining the effect of food, or various numbers, as well as things I am absent thinking about yet,
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[NOTE]
Longevity technology
GSK
Peelies from sun exposure relief technology: 10hda is published as reducing scratching multiple times; screen a decanoic ester library, that finds a molecule that does better than the multiple times less scratching that nude mice do when they have dermatitis and have royal jelly topically applied to them while being at greater potency per mg or microgram, Put some kind of dermis passing thing on or with it, beauty emulsions say they penetrate the dermis to bring active ingredients to the dermis so those technologies can bring decanoic acid esters to the living part of the dermis
so it can soak through the peelie and get to the itchy live dermis under the peelie. I have also read multiple pubmed journal references comparing topical dermis youthifiers and the references say some of them are highly functional so dermal transport media or moieties are to my perception functional
Oral version
Topically, harmless antibodies linked to fluoroethynyl phenibut like chemical, could possibly concentrate at the dermis.
An oral version with enteric coated liposomes to deliver the protein conjugate drug could take numerous minutes to reach the small intestine but make people feel better for many hours and as a pill is more likely, I perceive, to be utilized.
The possibility of a fluoroethynyl peptide or a harmless antibody linked peptide suggests less than 100 micrograms would dose the entire volume of a 70kg body, so a few kg of dermis is likely less than 11 micrograms per application, at $435/g (retail antibodies) that is near 43.5 cents a milligram or near .0435 cents per topical dose or .29 of a cent per oral dose
Is there such a thing as well feeling and appearing dermis, itchless and zero hue change skin puffiness causing chemical; one possibility that is similar but kind of different is topical vasodilator, possibly niacin, which i perceive i may have read about as a topical beauty treatment; if there is then doubling fluid flow at the capillary epithelia could make a topical peelie comfort medicine absorb twice as rapidly or ultra hydrate the dermis causing more rapid diffusion and greater activity of the topical drug causing more rapid function; I have heard of vasoactive peptides, perhaps they could function;
A zero hue change completely comfortable dermal vasodilator might also double the effectiveness of things like peptide beauty topicals, it makes me think though, they could just double the amount of active ingredient;
Find out if topical or oral phenibut, possibly a halogenated phenibut, or GABA active peptide effects dermal nerves to cause the removal of itching that about 2 grams of oral phenibut causes. A body side of the blood brain barrier possibly halogenated phenibut or other body side of the blood brain barrier GABA active molecule could omit CNS GABA activities, it is beneficial to have the drug be absent effects on things like driving ability, reaction time, or social skills.
Thick throat coating drink with peptides might have sufficient surface area to be absorbed as a kind of oral-like peptide dosing form, although I have heard of peptide doses up to 1 mg my perception is that at things like vasopressin and oxytocin it is much less, the most dose effective peptide I have read about, having not looked up other things is a mu opioid peptide active at nanogram amounts, I perceive I read about a halogenated peptide that was twice as effective; at an oral like mouth and throat coating peptide dosing form it is possible the pH of throat saliva could be modified and a mucolytic thing, perhaps something like a protease that is absent an effect on the peptide could make the peptide actually contact the dermis at the throat and mouth, the thing is though, what about stirring? A mm layer of colorant will just sit at a glass, for I perceive, hours, before diffusing; effervescence could do it, so perhaps a bubbly mini-beverage could make the body surface dermis soothing peptide reach the throat mucosa dermis many times more rapidly and before it was washed to the stomach; beneficially the peptide would only work at the mouth and throat so if many doses were consumed because the bubbly mini-beverage tastes good the dose would not vary that much
The 1/10 of a cent printed paper dose technology with the 1 cm^2 doses and enteric layered ink could be beneficial at the developing world, the thing is, what drug, like antibody linked GABA active peptide or drug, would soothe the dermis; tetracycline and possibly minocycline do build up at the dermis, possibly a GABA active drug linked to one of those molecules that has been screened to be a neutral biotic, possibly also finding a variant with greater dermal localization
An all natural product could also function, I do not know of any anaesthetic macroscopic or other fungi, but if there are any, notably GABA receptor active fungi chemicals, then those could be a rapid product.
Actually I am not aware of any natural product that effects GABA receptors, there are commercial natural products chemical libraries that exist, they could screen those to find out if any of the natural products effect GABA receptors, GABA the chemical does not pass the blood brain barrier but might diffuse through the dermis and is only a few $ per 100g.
Other neurotransmitters at the dermis could be anesthetizing, heightening response of anadamide receptors is unknown, a mu-opiate peptide that disintegrates in saliva, mucous of any orifice, and the stomach could be a topical anesthetic, perhaps a mu opiate peptide with a magnesium or calcium or zirconium or scandium atom in the middle of it could persist long enough at the dermis, or lasting about 90 seconds, but continually diffusing from the topical material would function
Orally a mu opioiod peptide attached to a harmless dermal
Localizer molecule, possibly an antibody or a minocycline variant could function. As a topical drug the peptide could be modified so that many enzymes degrade it so it would be nonseperable from the localization chemical which might also be made of enzymatically degradable nucleotides, peptides or proteins
Things that soothe UV Elie's could ask soothe dermatitis as well as a topic dermatitis
Theoretically about7.6 billion people on earth have experienced sun based peelies, so this could benefit people
I have not read about brain area localization technologies applied to mental illness drugs but it seems possible it happens, area (like neocortex) is a different thing than neurochemistry, like say all the neurons with AMPA receptors, or at antischizophrenia medication 5HT2 receptors at pimavanserin,
They could screen a library of fungal chemicals, noting fungi have numerous unusual chemicals after utilizing a radiolabelled acetylating chemical to acetylate a bulk fungal extract, so the chemicals pass the blood brain barrier they could separate the chemicals (more on that at a different note) and feed them to mice, one new chemical each 24 hours, and then brain scan them, and with 300 mice a month later would have 9000 localization maps; if 1 out of 100 had utility they would have 90 maps, also they get maps of where things localize at the body area as well; then noting what the concentration areas are they attach drugs to that fungal molecule and see if the molecules still go to the mapped area; they could come up with molecular variations on the fungal molecules that were absent any drug effect so the drug molecules the fungal molecules were transporting did all the pharmacological activity, it is possible that enzymatically degradable linker molecules could separate the active drug from the fungal transporter. They might do things like this now I do not know.
Separating chemicals from each other with microfluidics,
Another possible way is ion exchange resin inkjet printed beads, i think i have heard of printed microfluicics and i have heard of 3D printed microfluidics, it might be possible to inkjet print digital gradients of ion exchange resin component chemicals, then aim a warming laser to melt them so they bead up, then high frequency nonwarming pulse interval laser to stir them, making a digital gradient of different ion exchange resins responsive to a different chemical; a microfluidic channel layer is then printed atop this (or previously beneath) and each of the separate ion exchange chemical concentrators has its own plumbing, at 32 micrometers radius of the bead then there are 47,851 chemically different chemical separation locations on a 7 cm times 7 cm chip
and possibly
or if 3D printing are printed on peltier cooled paper; or 72°F stable then they melt, liberating contents when a laser shines on them
Another way to make an IER chip is ion exchange resin inkjet printed beads, i think i have heard of printed microfluidics and i have heard of 3D printed microfluidics. It might be possible to inkjet print digital gradients of ion exchange resin component chemicals, then aim a warming laser to melt them so they bead up, then high frequency nonwarming pulse interval laser to stir them, making a digital gradient of different ion exchange resin beads responsive to a different chemical; a microfluidic channel layer is then printed atop this (or previously beneath) and each of the separate ion exchange chemical concentrators has its own plumbing, at 32 micrometers radius of the bead then there are 47,851 chemically different ion exchange resin chemical separation locations on a 7 cm times 7 cm chip
Another way to make an ion exchange resin chip is
If you liquefy an ion exchange polymer with a laser or ambient warmth then use the actual multichannel microfluidics to transport the ion exchange polymer fluid to a particular well. It is it possible to fill 1 million different wells each with a different chemical component ion exchange resin; blending liquid polymers, using microfluidics, at a variety of ion exchange resin chemical components that are blended together to make an array of 10,000 times 10,000 ingredient gradientized different ion exchange resins, each of which will prefer to glom different chemicals than the other, doing that makes 100 million different ion exchange resins at a chip
It also makes me think this is a possible way to do what is effectively screening a library to find completely new ion exchange resin chemistries, if you then pump in the chemical you want to glom on an industrial scale, and have the microfluidic then sequentially (parallel versions could work) liberate the glommed material you could find the most effective ion exchange resin composition out of 100 million (wells) which is likely much more efficient.
Niftily, ion exchange resins tuned to find chemicals of moderate electric charge and higher lipophilicity tend to concentrate the 100 million chemicals most likely to pass the blood brain barrier and omit macrophage and leucocyte response; that kind of ion exchange resin chip could enrich the number of chemicals concentrated from the homogenate with chemicals that have more favorable drug characteristics which are then higher velocity at being turned into drugs
It could be possible to heighten ion exchange resting chemical concentration 11 times greater than wells with ion exchange resin fluid traversing sponge:
ion exchange resin highly porous sponge, blending saliva with rubber cement automatically makes a sponge so a chemistry of sponge making at microfluidic tube chambers could be straightforward, it is possible that rather than an ion exchange resin bead well you would just make a higher volume tube volume of like a (========) filled with ion exchange resin sponge along the access plumbing microfluidic paths; think of a view like a circuit board multiparallelism with tube balloons periodically, the tube balloons full of ion exchange resin sponge could have surface areas to the 3rd power causing them to glom with 32767 (32^3 micrometers) compared with (32^2 times 3 micrometers) at a well, that is near 11 times more material sorted at a similar surface area but sponge hosting volume
If ion exchange resins can glom 1-10 pct of their volume of product, and 47,851
1/32,000 of a milliliter is the volume ofa 1 cm^2 area 32 micrometers deep, if the ion
1 cm cube that is 2/3 tubes concentrates 1-10 pct of chemical so .067 ml of concentrated material and can be used 11 times, so .67 ml of material
Compared with the 27 item multicuboid concentration and sortation reactor which is utilizes 27 cuboids, each 2/3 ion exchange resin sponge tubes, utilizable 11 to 140 timesreactor
Parallelism is beneficial at chemical sortation and chemistry chips, noting the 1 cm^2 two thirds of it being ion exchange sponge filled tubes product sorter and concentrator, When assembling a cuboid (like 27 packages stacked three on a side) microfluidic chemical reactor or ion exchange resin cuboid form, a Lego (or better) interclick of perhaps 16 tubes per Lego circle thing to make a 27 times capacity reactor or product concentrator/sorter goes with having functional fluidic,and microfluidic connection between the cuboids;
the actually fairly mild 16 times 6 circle tube fittings times 27 cuboids times 6 sides all surface Lego circle connectivity reactor would have 15.5k connections, perhaps better than brickle blocks is tHZ (or, just possibly at some polymers lasers like the 3D shape deepwater laser scanner) weldable cube internals, so the up to 10k connections at a 27 cube Lego assemblable reactor (only about 10k connections out of 15.5k if you ignore the surface) could be Thz welded, puffed to fit, or even capped if leaky, at a yield of just 95% 10,000 connector connectiviyy that produces 95% or higher functional plumbing access piping at the reactor multicuboid. The microfluidics at each cube could have some adaptive routing paths to make all the reactor/concentrator well or tubes accessible. I think making these as spheres is also beneficial
The routing adaptive layer at the microfluidics makes it possible at a 27 cuboid reactor to route the chemical containing fluids clean withe reverse direction flow
Ion exchange polymer reloading as microfluidic pumping of new gradual chemical reaction to make new foam, laser or Thz
it is possible a soft flowing polymer with "brickle blocks with adaptive routing" could avoid the actually fairly mild 64 times 27 times 6 all surface Lego circle connectivity, perhaps better than brickle blocks is tHZ weldable cube internals, so the up to 15.5k connections at a 27 cube Lego assemblable reactor could be welded, puffed to fit, or even capped if leaky, producing 95% or higher functional plumbing access piping at the Lego cube. I think making these as spheres is also beneficial
Integrated circuit technology microstructures; doing electrophoresis at microsized channels that are likely larger than the one million lane microfluidic chip I read about; An electrophoresis gel that is only a gel when it is cooled can be partitioned and pumped around when it gently warms, although there is also the possibility of specific area of the chip warming with lasers; the many lane electrophoresis peltier cooled gel turns liquid at 16° then adjacent microfluidic lanes at 32 ° angles pump the chemical or protein enriched fluid at just that area to a new location on the microfluidic chip; 1000 lanes are loaded at one side of each electrophoretic lane, so each electrophoresis lane at the chip can transport 1000 completely different chemicals like proteins
There many ways to structure the microfluidic channels, some of them remind me of the connected and branching conductive lines on the upper surface of photovoltaic
Looks kind of like (→≠») or ==‡== where fluid flow direction meets a bunch of channels connected at an angle or #€[‡] other branched channel geometry
The liquid sample with liquid electrophoretic gel material that gels at 16°C loads at []‡ or ==‡== then peltier cools the multichannel ‡ to gel, then an integrated circuit, which just possibly is at the base of the electrophoresis chip if it is made with integrated circuit technology as compared with polymer technology or MEMS technology, causes voltage at the long (‡)channels on =‡= causing the gel to sort chemicals, this can all be acvomplished with branches of branches at one layer, or, layer atop ==== has another ==‡== fluid path on it; each concentration at the gel channel can be liquified with lasers; microfluidics utilizes published pumps so above 16° C when the === areas when the concentrated chemical are liquid they are micro fluidically motionized to the perimeter of the chip for further use, alternatively they can just be micro fluidically transported to where the yeast are; at another version the microfluidics transport the electrophoresis products to a bunch of wells on a multimillion well integrated circuit technology like planar area, and then to place the yeast and nutrients, the mechanisms automatically, or if feeling thrifty, a human gently places, or possibly even mists the multimillion well plate that has the plurality of separate concentrated chemicals that the microfluidics have placed at predictable locations and at a database, the actual yeast and nutrient solutio; the wells have the volume capacity to feed yeast for 20 unmedicated yeast lifespans noting that yeast now can be made to live 400% longer (salicylic acid) so that way if the 99.999th percentile of longevizatiom causes a lot of yeast longevity they will have nutrients the entire time.
It is possible putting the entire thing on an ultrasonic transducer will heighten fluid diffusibility
To produce a larger amount of chemicals, utilize some other channel sizes, make the multichannel integrated circuit technology electrophoresis chemical concentrator produce 100 MCG of product per each second or third branch (or layer) of sequentially purer electrophoretic ==‡== channels, 1000 or 10,000 ==‡== functioning in parallel, loaded from the sides of chip with larger distributive microfluidic |[]| perimeter channels, provides higher volume of material being concentrated; there are 2500 preconcentration material loader channels on each perimeter side; 100mcg times 10,000 ==‡== channels processes 1000 mg, 1 gram of sample each full cycle, at 20 minutes per cycle then 72 grams of sample can be separated per day, 14 of these chips stacked in parallel can process and purify 1 Kg per 24 hours
If a yeast weighs a microgram, and it is possible there is a yeast species that massive (1 million yeast per gram) then dosing the yeast at the human equivalent of 2 grams to 1 micrograms human equivalent dose with the chemicals concentrated at a microfluidic electrophoresis chip is possible
Notably having millions of wells at an integrated circuit wafer technology or even MEMS polymer form makes the amount of locations so the yeast can be dosed at numerous different orders of magnitude, about 7 orders of magnitude between 2 grams (phenibut) and 600 nanograms (ethynyl estradiol) human equivalent dose at 8 wells of yeast each to get p
What if the microfluidic chemical sorter had 100 micrometer channels, and 100 of them on each perimeter side that are moving preconcentrated material at each perimeter side of the chip, well that perimeter is a surface area kind of like one cm^2 of motionized fluid; Depth: at 100 micrometers of 16°C electrophoretic liquifiable depth, and 11 minutes per cycle to traverse up to .5 cm (before branching) while having 10,000 micro fluidically addressable tube segment tapping branches (noting the 1 million microfluidic lane chip I read about) then it is like a volume of 1/100th of a ml each 11 minutes or about 1.3 ml per 24 hours. A 7 cm^2 version would produce 63.7 ml of 10,000 sorted chemicals. If less specific lengths of the liquified electrophoretic lane tapping tubes were utilized then you could get larger amounts of 1000 chemical fractions, at 63.7 ml that is 63.7 mg of each of the 1000 different chemicals, although it is actually different than that from solvent mass, so 6.3 to 32 mg per 24 hours could be from 90-49% liquigel solvent
The thing being that the person is producing mg or more of a longevity drug to characterize and quantify at 6 month 96 well plate fish or mice,
If 1 out of every 1000 or 10,000 (different chemical quantities from different resolutions that make .63 to 6.3 mg of concentrated chemical to dose organisms with)
That makes 10,000 or 1000 microfluidic branched channel electrophoresis concentrates, of different numbers of simultaneous chemicals from few or even one to ten times as many from ultrasonicated endolith homogenate. These 1000 or 10,000 chemicals could then be screened knowing, kind of, what they are. Also the microfluidic chip could have 10,000 wells on it so an eentsy sample could be removed if really precise characterization is the thing to do. The amounts, going with the convenient unrealistic presumption of 1000 chemicals of equal amounts is sufficient to dose a mouse with a multidays of dose produced every 24 hours, or at 10,000 chemicals, c elegans. The c elegans could be dosed throughout its life from one 24 hour output. This is
A way to make 99.99th percentile of longevizing chemicals at 24 hours. If age batched c elegans were used for testing then 6 or 9 days would produce a longevity increase %.
Finding the longevity drugs:Use microfluidics to connect the multimicrochannel electrophoresis chemical separator to 100 million yeast colony wells or 100 million human tissue colony wells then use the: the more GFP it produces the longer it has lived varieties of yeast or human tissue culture cells, these emit more light the longer they live then have camera note the most light emitting cells at wells,
It is possible that finding a most longevizing chemical from half a billion different chemicals longevity drug chemical could cause a person to systematically follow twig to branch on a half billion leaf treeee, possibly doing all 29 Binary experiments to find the identity of the chemical. exposing yeast to half a billion different chemicals, then utilizing flow cytometry to find the one with the greatest light emission tells that if it turns the yeast into anendolith lifespan longevity organism it is beneficial to test it on mammals and give it to humans;
Utilizing liposomes with, approximately, just one chemical at them to quantify and characterize new longevity drugs:
With the possibility that a continuum gradient electric charge or pH gradient generation around liposomes, causing them to ensconce different things (or putting phosphatidyl serine and alcohol at an electrophoresis gel that liquefies above 16°C then beaming ultrasonics on the phosphatidyl containing gel produces liposomes to form right there, at a micrometer or eentsier sized piece of a chemical/protein band, ensconcing just that location's chemicals at that electrophoresis band generates a billion or a trillion liposomes, each with mostly just one particular chemical;
You blend the one-liposome-one-chemical liposomes with a one yeast one liposome dilution at a container of fluid, or possibly decanted to make a monolayer; longevity chemicals make the yeast live longer and the most fluorescent yeast has lived the longest, the longest lived 700 yeast are detected with 20 million yeast per second flow cytometry and a numeric characterization of that entire library like endoliths or the kings holly can be made. finding something that makes yeast live numerous orders of magnitude longer and noting flow cytometry lets the yeast live on, many of the yeast remain alive
Then there is a way to trace the long lived yeast to the liposome it ate, and the chemical at the liposome; it has to do with the sensitivity of isotope spectroscopy at flow cytometry, the liposomes can have a large location specifying dose of stable isotopes at them because the electrophoresis gel either migrates a gradient of isotopes with 2-6 different isotopes migrated from each distal part or face of the gel before electrophoresising the screenized material like kings holly or endoliths; so the
isotope gradient, deuterium from one distal part, nitrogen from the other distal part, phosphorus from a transverse side and oxygen from another transverse side; each liposome also then gathers a region associated multiisotope ratio at amounts that can be seen with spectrophotometry of the yeast at the flow cytometer if that narrows the content of the liposome to an eentsy area of the electrophoretic gradient distance (microfluidic is micrometers) then the name of the source and its library of congress number is known and then the process is repeated to find the page paragraph the particular chemical molecule is
on.
Microfluidic version, transport numerous nearly identical electrophoretic liposomes sequentially to the yeast upping isotope dosage two or three orders of magnitude, and heightening actual chemical dose.
Liposomes are make able at different volumes, it is possible that liposomes with 300 times more dosing chemical are valued or possibly really eentsy liposomes with higher chemical/spatial resolution are valued.
possible then when a trillion liposomes form there could be a billion liposomes amongst those that had mostly just one kind of chemical or molecule, the one near them on an electrophoretic band that could be ensconced into a liposome at just that minute variation in isoelectric point, pH, p(some other chemical like NH3) (pNH2), so with a trillion gradient formed liposomes you get a billion mostly one chemical liposomes, (even though only a billion of them are highly focused)
Then After dipping, rinsing, liposome surface reacting, the liposomes with something like ribose or something yeast like to eat, put them at a dilution fluid so the ratio of liposomes to yeast is one liposome to one yeast; the yeast eats the liposomes then You can tell if the liposomes chemical longevizes because things like known longevity drug liposomes make their individual yeast live longer, and the liposomes volume and appetizing coating can be adjusted to get the highest ingestion and longevization response
Does this work with daphnia; could you laser zap an isotope gradient preloaded then longevity drug electrophoresisized gel to make eentsy 11 micrometer sized daphnia food cuboids, then feed them to daphnia to characterize and quantify the longevity effects, doing flow cytometry with spectrophotometry to find the isotopes that describe the location on the electrophoresis gel which tells which chemical book I'd or neighborhood it is from; daphnia are possibly a better longevity quantification organism than yeast.
Could isotope labelled electrophoretic liposomes screen billions of potential antibiotics rapidly, the bacteria that eat the liposomes with the most powerfully antibiotic fluotesce the least when all the nonliving bacteria are orocessed at the flow cytometer. new antibiotics save lives
Grow a sprig of the king's holly in isotopically labelled water, or perhaps do gene therapy on it with isotope labelled DNA, or provide it with isotopically labelled amino acids, or do all three with different stable isotopes; then do electrophoresis like microfluidic electrophoresis or bulk liposomal electrophoresis then when the flow cytometer spectrophotometric thing detects isotopes it is detecting them on actual longevity chemicals
It is possible that some drugs or other chemicals have very high area localization at the brain or body as they are, but that nobody knows of any illness linked to that highly reachable mapped area. Based on how it would likely function to attach another molecule, a drug, to the chemical that reaches that map area they could research the highly reachable areas to find out if adjusting their function would benefit humans, anything from actual medical treatment to causing the highly reachable areas to be what I have read is called better than well
Localization mental illness drugs, keep anti psychotics out of sleepiness areas if they still function
People create ways to keep protein from gunking up tubes, it is possible that unlike proteins, peptides, which can also be drugs, have chemical things which make them much easier to keep ungunkifying, from being able to clean all the peptides off of them off with an enzyme, possibly a deaminase, to drastically fewer gooey nooks at the molecule from having masses and structures up to hundreds of thousands of times less complex, it is possible that peptides screened (or produced) at microfluidics are easy to keep from gunking up areas, surfaces, connectors and geometries that accumulate material, microfluidics technologies at peptides could be clean, fast, durable, and with longer reliability cycles; screening libraries of peptides as longevity drugs with 1/1000th the gunkification at chips could heighten reusability which makes, concentrating, sorting natural peptides better, also absent gunkification the thousands more uses per chip makes it hundreds of times more affordable. From the perspective of making drugs and molecules that benefit people the 2019AD also noting the combinatorial space of peptides is kind of like many factorial and new completely artificial amino acids for peptides have been created, so it is a nonfinite factorial there could be a multihundred times better ungunkiness, tidiness, rinsability at peptide sorting and concentrating chips.
Some peptide libraries that could be mass screened for new longevity drugs: if you divide any protein into pieces about half a hundred amino acids long or eentsier it becomes a peptide so any longevity causing proteins could be made into pieces and screened at yeast in the billions (flow cytometry characterizes 10 billion yeast a second) so if the yeast are engineered to make and accumulate more green fluorescent protein the longer they live, it is possible to find out which yeast have the greatest longevity increase. Longevity proteins could be things like naked mole rat organ homogenate, any electrophoretic band that is at 35 year beavers compared with mice, any electrophoretic band from voluntarily provided, or not-alive person protein differences between humans and other primates, protein bands from termite queens (50- I read, 100 year longevity) not at other termites, the protein band differences between the 17 year part of the cicada's phenotype and its one month long mating form, queen bees and regular bees, the longest lived non s cerevisia yeast and s cerevisia and the briefest yeast, electrophoretic protein bands at the kings holly, 40,000 year lifespan thus far, with the protein not at a few other plants, protein bands at endoliths of numerous species (fungi, algae, cyanobacteria, bacteria) electrophoretic that are not at similar organisms, also noting whale longevity the electrophoretic protein bands at 214 year old whale tissue from non alive whales, or 214 year whale tissue from parturition related tissue in the water, that are absent from other whales; note that there are numerous others and that just these 22 could be macroscopically electrophoresized to get 10-1000 micrograms to dose the yeast with.
Also it would be beneficial when generating the peptides, rather than using enzymes, or even a many enzymes at one flask approach, to divide the proteins into peptides at nonpredictable locations because if you always use an enzyme that divides with lysine then the peptides will all have a distal lysine on them, one possibility is UV radiation, other radiation, or bubbling O3 through the flask
Spectroscopy of isotopically labelled peptides, would a spectroscopy beam at a flow cytometer looking at a yeast be able to see femtograms or picograms of radio labelling from a peptide at the yeast, perhaps, perhaps not, what about a one per 100,000 likeliness of seeing the isotopic labelling and the 20 million yeast per second flow cytometer I read they thought they could make, then that is 200 yeast saying which peptide they have been dosed with per second then that is 630.7 million peptides screened annually, with parallel machines, like 11 of them, that is 69 billion peptides screened for longevity effects. There are 2 1/2 longevity peptides out of that I have heard of, so at an extreme, 1 million published peptides so they might find some from a million isotopically labelled peptides that the first 14 days of spectroscopic flow cytometry of yeast finds, and the flow cytometry of fluorescent proteins notes have highest longevity increase. They could then utilize about 11 96 well plates of c elegans or 6 month fish to quantify the effects on vertebrates of the most longevizing 132 of the peptides.
Use peptide sequencers, and if there are microfluidic peptide sequencers, noting the million channel microfluidic chip i read about, creating combinatorial peptides based on software, like AI, like deep learning AI that predicts effective longevity increase and then makes those longevity peptides which are screenable at yeast.
Precluding protein gunk up at microfluidics, at something like fungal or algal endolith homogenate longevity chemical screening or clam homogenate longevity screening with numerous proteins at the ==‡== microfluidic microelectrophoretic sorter could direct each concentrated, separately tapped band of material at the gel to a microfluidic lane that has an interior polymer (or other material) surface charge that minimizes protein accumulation on the channels sides, at that particular protein's actual characteristics, kind of since you know the charge it is at and responds to you can have it traverse channels where that channel's interior charge is neutral or slightly surface-diffident whichever causes less gunking up
Longevity technology: AEDG (Epithalon) is a peptide published as causing 24% greater longevity at mice, and when administered with thymosin, it makes people 4 times more likely to be alive after 6 years; there are now synthetic amino acids they make, so molecular variants of the A, E, D, G amino acids that are synthetic could be made, assembled into new versions of epithalon and quantified as to longevizing effects; with two new atom swapouts or new atoms per each new synthetic amino acid, that is just 16 binary variants to screen at mice, yeast or human tissue culture, notably this provides a kind of nifty rapid research utilizing human cognition originated drug creation. Noting using a D-amino acid is part of how vasopressin was modified to be orally active a person could enjoy, like, and value making an orally available D amino acid or synthetic amino acid version of Epithalon. Like if I were making a variation, thinking as a human, I would find out if acetylated synthetic amino acid variations on any of the amino acids in AEDG were previously existing, then distal to the part of other things Epithalon they might think Epithalon attaches to or activates things with, I would put the acetylated synthetic amino acid because I think it might cause the acetylated amino acid version of Epithalon to pass the blood brain barrier more effectively, predictably, or pre looking things up online I would find out if achiral (nonchiral) synthetic amino acids have been produced (imaginably a dimer, even like the G at AEDG being doubled, a new achiral glycine)
If this were at a public biotechnology maker space like they have in San Francisco and New York City then it would be nifty to have each of 7 or 14 people each think of their own version of AEDG with the makerspace maker shared enthusiasm and actual craft of making, although possibly just ordering (another pineal gland peptide distally attached to AEDG might have synergistic longevity effects, causing greater longevity increase at mice than the published 24%) things. Also if people at the makerspace knew about AI, or even just the deep learning packages they have, then one of the makerspace people could make a computer program that uses deep learning to create AEDG variation molecules, as well as other longevizing molecules and enjoy doing that, as well as of course wondering how well it would do compared with the human originated versions. If AEDG has a longevity effect on c elegans or more beneficially 96 well plate 6 month fish, then 3 of these plates would give results on the 7-14 people's AEDG versions times 2 or more variants each, utilizing 8 organisms to get a p value, that is 224 wells of fish as well as c elegans to quantify all 14-28 variations.
There is also screening a library to find a more longevizing version of epithalon, from a synthetic amino acid perpective, Modifying the four amino acids to have four atom swapouts per amino acid then that is 2^16 screenable variants, near 65,536 versions; going with the idea they could modify the Epithalon on purpose they could make eight atom swaps or additions each at the two amino acids on the side of epitalon that actually activates things (if there is a receptorside, make the two groups of four atom swaps at the receptorside) then these 65,536 could be screened at yeast as well as human tissue culture to find 99.9th percentile of greater longevity increase from the molecules screened. I do not know if Epithalon makes c elegans as well as daphnia live longer or not, if it does then these could be utilized to compare different AEDG, Epithalon variants.
I perceive Epithalon might be tolerated at a multi-order of magnitude dose range, if it is then that suggests something Epithalon activates gets fully activated, kind of saturated; finding out what that saturated thing is, then making more of the saturated thing, or possibly supplementing, as a longevity drug, the amount of the saturated thing could be a new longevity drug; also i do not know if the saturated thing is a cell type, a receptor at the brain (CNS) and at many places at the body, or a chemical. If it is a cell type or receptor then the genetics of the saturated thing like SNPs, alleles, or copy number variations could be part of the genetics of greater longevity; if it is a cell type or receptor then the epigenetics that effect the amount of DNA transcription that effect how frequently or how many of that receptor gets made could be longevity heightening epigenetics, some epigenetics effects function at multiple generations of humans so it is actually possible taking a tuned HDAC inhibitor could turn making lots more of the saturated thing on, or make lots more of it, and that the heightened longevity effect transfers to your children and grandchildren.
Does making BDNF nerve growth factors or other growth factors at the pineal gland heighten longevity and healthspan.
Other pineal hormones, Epithalon, to my perception was developed from researching pineal peptides, it is possible some of the other pineal peptides are more longevizing but at the time a four amino acid quadropeptide was particularly easy to purify and make, it is possible there are lengthier amino acid sequence pineal peptides that can now simply be ordered to be constructed online and screened at mice to find out if they have greater longevizing effects than Epithalon
Does a 300 year lifespan tortoise have a pineal gland? What about a century bird lifespan bird, could a recently alive, hospice-care like administered multicentury lifespan whale's pineal gland have its peptides sequenced, all of these pineal peptides could be tested at mice to find out if they are heighten longevity above epithalon's published 24%
is it possible to grow stem cells from a multicentury lifespan whale, possibly using traces of GI tract tissue at whale poo as a source, or a plucked hair, and then differentiate the multicentury longevity whale's stem cells with tissue culture to make a source of whale tissue to develop longevity drugs from.
Do 300 year tortoises and 300 year sharks have pineal glands, if they do then their likely varied pineal peptide sequences could be characterized at mice as to longevity increase to find a peptide more longevizing than AEDG, epithalon
Longevity genes and proteins at multicentury whales: at humans, HARs, human accelerated regions are areas of the human genome that have changed and diverged with the most velocity, possibly as compared with other primates, humans living much longer than another primates could be linked to HARs, so at multicentury whales do they have cetacean accelerated regions compared with other whales, if they do then genes causing greater whale longevity could be located among these CARs, humans comparing those CARS, as well as human HARs To each other might find shared homologous genes of longevity (compared to nonhuman primates) with the multi century whale versions of the homologous CAR and HAR genes shared areas being particularly longevizing, the actual gene products, like proteins, of the longevizing versions could be heightened at humans as a longevity technology as well as CAR HAR most longevizing genetics gene therapy, germline gene modification, longevity drugs, it could also be that Whale CARs (comparing nearest genome at other whale species) have a completely non homologous to human genes longevity heightening gene area that could be used to develop new longevity techology as well as longevity genes as well.
CARs and HARs as sources of longevity genes, could be sources of longevity genes that benefit humans even when they arise at other species, imaginably noting epithalon's 24% longevity heightening effect, and that i think brain development areas are among the human accelerated regions, HARS, it is possible if you make pineal effecting HARs genes part of the mouse genome the mice might live longer
Complemtary
Thinkable: noting three of them as a proof is it possible, along with longevity with healthspan and wellness and being simultaneously benevolent and beneficial and effective at raising children, that there is anything at humans where a larger amoumt of it is always beneficial? This could actually have a mathematical interpretation where some axioms about iniverse math and topology create different and beneficial math limned options;
Getting around all the math of how varieties of sharing can occur at different math systems, dividing odd numbered things on a curved surface or a planar surface causing equal, unequal, matrix equal but anisotropic kinds of partioning, as well as the mathematics of nonpartitionable systems, also interconnected or stand alone systems where all agents always have perfect information arising from the math definitions of the system they are at, consider a person with 360 spherical vision living comfortably in a pleasant easily climbable bowl, who has used science to verify that like 20th century humans communicating the, to my perspective, MWI modified idea, that there is no thing space expands into; the person with the 360° spherical vision actually, at that math space, sees it all, and has the mathematical topological space of having perfect information; the "outer surface" of the bowl is absent detectability with physics, and to have the math function with everything that has ever been measured supports there being no exterior of the bowl (gideon's trumpet, nonfinite length, enumerable surface area possibly is reminiscent of a bowl with a math space where there is a region of presence and non presence at a thing); finding new math spaces that optimize human well being is beneficial, because they make worlds where polythings align with goodness
With math as a beautiful prompt, are there things that if there were heigtened amounts would always be beneficial; well i think it is possible to create a math space where kind of like a topology of all beings having perfect information (360° spherical vision unisided dish), any recombination always produces a more beneficial change in form than omitting any kind of recombination or sorting, while the previous to change universe, at that mathematical topology, is to any sentience fully optimal; any change could heighten an aleph number that a mathematician describes the universe' topology with, one possibility is
So thinking about where i have presence of being, is there a heightened amount is always beneficial
If i can just make atoms, is that a more is better thing, anyone can use them, and noting that the universe is good it just causes a greater amount of universe, using math the new atoms could have equational creatability at various equational areas of the universe, sort of like the way mathematicians are able to definitionally limn an area where "you can add 2 to anything and it will retain its odd or evenness" there is a math system like a topology where it is possible to put more atoms, at a kind of
This is different than the kind of langiage effect "can i find an exception" this is making new math environments where if you say torus then another person saying, thete are two or more circumferences is the way it goes( there is an exception though, if you put a gravitational singularity at the middle of a torus then that middle circumference ballons towards it and at 1 dimensional numbers a balooning occassion causes the middle circumferance to be identical to the outer circumference;
A computer scientist might say, oh, what you mean is algorithms with proofs that limn their behavior, and, among other mathematical forms, i think you would like thinking of mathematically limned "proofed" algorithms that, noting the universe is good, make the universe gooder, so you are utilizing a moment to think of thimgs where at any mathematical or definitional space a greater amount of any anything is gooder;
Whether it has an aleph number or not heighten the universe' aleph number
Just make more atoms, is there a way to figure out if just makimg bosons or just makimg fermions is gooder, have you asked aroumd about a greater quantity of spontaneously resolving quantum objects or also a greater quantity of quantum objects that are unresolvable
Is there a gooder quantum object like a linear photon that gradually builds its brightness so that any organism that liked it could experience it, or if they felt sleepy could just shut their eyelids and go to sleep, , or a true analog thing that is. Planck unit nondependent
If you have a network of n objects such that when superimposed the additive wave is always positive and high thing to the³ compared with thing² and the top half of ac is at an etalon and the container size and when I say container it could just be a parabola of frequencies with the upper part of the parabola a wave frequency larger than the span of the universe and the optics such that only optimal images would retroreflect
A parabolic mirror at a math space where everything was reflected twice at a frequency doubling crystal such that if it were reflected once it would traverse to outside the network and diffuse to the same frequency as the nearest most light emitting object, then shape the topological space so that always happened, all the images viewed would be right side up and the right handedness would be at each image the reflections would be a clearer image each time because they are vector graphics, a casimir flashlight could provide the light that gets
Casimir flashlight automatically motionizes vector graphics
Casimir flashlight attached to an oscillator always gives the oscillator a nudge with some surplus and the surplus makes the parabola higher and raises the curve at the base or at a math space does the up widening traverse thing as it is topologically gyreless, the parabola lifts at the same velocity the math space expands so the proportionate location does not change while the vector graphics reflect twice all the time with the raising and expansion causing a larger number of vector graphic reflections of higher resolution while (at a size changing topological universe)
This could also be accomplished with a gradient refractive image lens at a plasmid shaped topological universe, any occurrence at the sides of the lens would be at total refractive index, and the network nodes at the interior of the tir would experience connectivity without reaching the perimeter; an optical computer in the middle of a curved optic with 3d hat wave, egg cup, such that the tir caused retro reflection that was also a vector graphic; so what the network experiences is heightening vector image quality as the parabola lifts and heightens while the nonperceptible tir at the sides of the plasmid expanded, the duration of the reflected vector graphics is such that any node of the network was equidistant from a light patterns gradual and normal pace versions, the cofocalization of the sides of the parabola would cause the connectivity of the network as well as the nodes to accumulate presence of effect in phase with the network nodes that were around, with math I think you can have a simultaneous group of equations that does that, casimir flashlights work in water and the light would accumulate in place if there were no nodes, noting million year endoliths the nodes would usually be there and they could process the vector graphics from the sides of the parabola or each other the casimir flashlight could actually be a coating,
Thinking about math, although i perceive observing a new gooder thing and heightening the quantity is a gooderness maker
Is it possible; what is a way to observe a new gooder thing?
Well, you could find people that observed new gooder things, then with technology simulate them nonsentiently then actuate a trillion of the nonsentient simulations, then broadcast the new gooder things they observe at a math space of
Simultaneous linear equations of the amount of streamlining, also words that happen at my mind that are 40% or less of what i actually thought, although these 40% words may have a participateable theme of their own, intimations of pattern meaning from form being different
A drug that decreases streamlining some number of units, while being actually recognized as heightening absence of streamlining whete teduced externsl patjwayization is like 900 units of less automatic so another person bringing up an opportunity for a voluntary action would have 90 0units of greater possible voluntaryness this simultaneous equation space where automated respone forms habe less prompting while a new beneficial thing is questing agter psrticipation contributes to a mathematics supporting the possibility of voluntary action (like math supports physics) notably there could be many such drugs which happen to cause gooderness at most of the cumulative occurences, also there are some drugs that cause, at me, a high, while also decreasing streamlining and possibly 40% thoughts, a drug that might do that is phenibut, a nonintoxicatimg drug that removes the abridgement of actual feeling and thouhht of intent 900 units while a different benevolent thing is alignig 900 units of voluntariness as utilization capacity with the change like a beneficial thing, they favor
Genes of openness to experoence; genes of the words in your head being some percentage of what you mean, like actually 100% people, 90% people, 40% people being genomically compared and then their genes used to predict the statements about"words in my head are(amount)% that I mean", that a sample of people with genomes at a database make; when the computer model of the genes that cause some version of this is 95% predictive then the genes of 100% of the words in your head actually mean are promoted, perhaps even made available as a sample with gene therapy or drugs, then to the amount they can, people can purposefully opt for, along with their previously actually knowing what they mean, what they thought, and perhaps for some what they intend, the actual words in their head, like casual narrative thinking, such that then articulate that
It is my perception that the debrisifying or content mutation or content simplification that occurs when the words in my head are at a 40% thought that the actual capacity or ability to be simultaneously cohered at a voluntary action opportunity, so it is more actually voluntary like numbers derived from simultaneous linear equations solved amounts of the possibility an act is voluntary gets greater the more the words in your head are 100% what you mean;
Somebody reads an advertisement for something that is actually beneficial, if the words in their head are 100% of what they mean, and they actually get the beneficial advertised object, then their capacity, like their available amperes of voluntary, is more voluntary than a words at my head communicate only 20% of what I mean person, so this is genetics and drugs that heighten the capacity of humans to be less encumbering to others sense of wondering if they are being fair, if a 100% person volunteers it may actually be more ethical quantified like amperes (compared with ethical the dictionary definition)
genes of
It is possible a nuclear chain reaction, noting it always decoheres more things than it resolves, continuously might be a simple sytem that is unresolvable, a person could only ever say they saw part of it; also some of them are autocatalytic; what is the eentsiest always quantum unresolvable system that humans also like, white light, being physicsy, is definitionally omitting of sufficient observation to be described as its components, although there could be a math thing, or even a physics thing like we emitted some white light so we know how many watts occured,
Stomach lining 72 hour rrgrow
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Do placentas contain longevizing chemicals and genes, or perhaps also deleterious chemicals to immunize against or epigenetically decrease; placentas, seem like they are super well throughout pregnancy then, i perceive i read, disintegrate at high velocity, i am imagining less than an hour after birth, It could just be autodigestion with enzymes, possibly so things like cows find eating a placenta easier, there is also the possibility that they emit disintegration chemicals even when continuing to be connected to the mothers uterus, do placentas have post birth chemicals which if circulating at a nonpregnant person are deleterious, are genes of placental disintegration activate at nonpregnant people, what do those genes do at a nonpregnant person, would focused epigenetic drugs decrease the amount of what might be deleterious proteins produced from genes st nonpregnant persons; mouse rat tissue transplant is published, the larger abortive rat placentas or duration of research sequentialmultiple mouse abortive placentas prepared from liquid nitrogen frozen placentas could be compared with sequentially gathered live birth placentas so there is a dose every 24 hours; if there is an absence of mouse immunoreactivity to beaver placentas one or two beaver placentas, homogenized, centrifuged, and the supernatant used as a dose, could be administered to age batched mice for many months with the p
High velocity placenta disintegration after a successful birth reminds me of the absence of the octopus sex gland causing eight times greater longevity, also the chemicals at marsupials pregnancies could have different chemicals to screen that have some effects, there are numerous homologous genes at humans and marsupials
Think white
Things humans ever perceive that if there is a greater amount things are gooder
Math spaces like topologies or groups of simultaneous equations that create spaces where all items are fully optimal and liked at any consideration, if change occurs then the change is at a perfect knowledge (math words) which could be nonsentient, that the new changed optimal is more beneficial than the previous optima; if a change occurs without any initiation at a perfect knowledge environment, math, possibly network effects, cause the change to be more beneficial than the previous optima;
There's an image of a travel path that is ±hill both circular directions, it looks like it works because, to my perception the math space of 2 dimensions has different things about it than the math space of 3 dimensions; if I knew a mathematician I would have them advise me on how to make a topology, geometry, data structure, group of simultaneous equations, optimally with continuous curved mathematics that caused anything at that space to be optimal, if purpose occurred new optimal that a perfect knowledge omniscient (this can be nonsentient), observer recognizes as more optimal that the completely optimal thing that preceded it; if a nonsentient origin of change occurred then
Pleasantly giving greater and greater amounts of white light casimir light globe in a museum where every piece of art you see is even more optimal than the previous
Sequential networks at a benefit producing energy environment;
Could be accomplished with chronology, notably global art gallery could have perimeter of time expansion so as the casimir light gets light emittinger more artworks from further get illuminated while the previously near field time perimeter artworks are part of a mathematical topology gooder mathness of network effects that go optimal;optimaler;non sentience sourced optimaler that the math that networks is limned with
Just like a seed and guidelines, or a loop and a disk drive head can make a bunch of math, it is possible there is a parsimonious description of an optimal;sentiencified optimaller; non sentieceified optimaller possibly like a topology mathenatical system that is say all distal sides up or distal sides alternate, center is minimal perturbation (minimax curve), or at electrons on a van degraff sphere the field equation days spread out to equidistant points; so I think there are some parsimonious math descriptions of a trioptimal consistent math thing
So I heard about networks but I don't know anything, I think math networks that share state in realtime like a dish of water of a particular length that has a soliton in it would cause chronodurable geometry states if or when the soliton oscillated differently or dissipated, at a mathematics of a multioptimal network then it would be optimal
then a bunch of vases, each full a different amount, when all connected together will normalize the water
Optimized multioptimal basis description of a mathematical class of networks, the extensible capabilities, are produced at an always optimal environment which could cause anything the network does that the network has any referent to is also optimal; these are math networks with all that math stuff about amount of connections to neighbors, propagation, values (is it like floats, passable object classes(mp4), neural network node contents, aleph numbers)
As well as has virtuous cycle attributes
Multioptimal math with a network that does change causes optimalness where aleph numbers are items at the network and previously described is how changing the aleph number of MWI universes causes a different nomfinnitude of them to be authentically white benevolentultioptimal math space is a preferred configuration because the things that can occur at an optimal network are continuously optimal
Use green shift to make water lifts up valve, changes valve setting, changes the way water lifts up valve cycle like a math thing, doing this a bunch makes a time pump, a quantity of say atoms that have been made to have been energy and matter adjusted from green shift
Could do simple math functions like if there is a vector, or more than one thing, do matrix math on it to
traverse time that they gather together if they fall apart, or have energy distributions minimax point, opposite of minimax curve, or as a if there are two things at once, like calculating a new vector from making an arrow out of two other arrows, the length of the resultant arrow vector reminded of an electret) where if they
Library magazine put gather display; some things are only likely to spontaneously arise where they will succeed, preassured,; what if magazine display was 5000 times more likely to occur in a city of over 3 million, causing 99% likeliness of being imitated brings up the possibility of virtuous cycles that spontaneously arise where, pleasant that they are virtuous, they have a likeliness approaching 100 that they will continue and a near 100 likeliness that if humans are area agentic beings, human participation is voluntary and humans like the virtuous cycle so much it is near 100 pro0agation
Plurality of math forms that are mulioptimal; once an math form like an equation is found at some math there are vistas of generatable equations, it is possible that some of these equations will be math universes where preassured generativeness
Causes them to come into being where they will be authentically multioptimal
The generation of a multioptimal mathematical embodiment on earth, where I did not take a shower; it is possible that a vista of multioptimal equations will have a plurality of instantiations where if some or all of the network components are removed the system will continue optimality, so noting earth, where I did not take a shower if some of my dandruff alights on a circuit board, modifying the network with outside of network content the particular equation at the vista of multioptimal equations that is tested as having the greatest maintenance of multioptimality is the equation the network is built with
Planck length time crystal membrane from being Planck lengthy always has topological membrane shape that causes network to be locationally mathematically congruent with the equations of multioptimality
Eentsy branches to Planck length make time crystals and actualize multioptimal network geometric match space
Math of internet packet topologies
There are many networks at 2019 distribution networks, electrical networks, many-few-node networks like alibaba.com, people 5 year olds sit next to and talk to in kindergarten, phone tower backbone to WiFi sharing phone networks, it is possible that the 10,000 networks people are most cognizant of could be classified and schematized with software then find out if any of them are mathematically translation space translatable to multioptimal networks, of the first 900 that are those that would cost less after going multioptimal would be restructured, possibly just changing a few nodes and structuring data differently would vause multioptimal mathematical form, as the optimality wss perveived at humans as having value then the other networks, as math state spaces are made multioptimal
If they hosted computing molecules instantiating multioptimal networks then endolithic organisms (algae, fungi, cyanobacteria, bacteria) that have lived a million years could be instantiating multioptimal networks, that suggests that it is possible for a network, like all the linked physiochemistry of an algae, to have multioptimal function, as a human finding the math of and building of multioptimal networks that replace other networks that humans like less has value
At MWI universe technology it could be possible to modify the topology of MWI universes to favor the spontaneous generation of only multioptimal networks, and at such universes the emergence of preasssured multioptimal networks would occur at concentration of matter and energy
Cssimir flashlight snack ai lives on
th of thimgs
Longevity technology
There are perhaps more than thousands of species of easily cultured yeast and algae, biologically transformed 10HDA(10H2DA) could come in hundreds or thousands of molecular variations, these could be tested at c elegans and mice, and just to be entertaining finding a yeast and creating a product for less than $5000 could be possible at $32/hr at an MIT undergraduate
40 hours
10 hours
Get list of yeast cultures available from internet, perhaps 300, at $20 per culture that is $6000 so instead get the 72 most different from each other species $1440
Culture 40 flasks of yeast $200
Matrix combine 3 yeasts at one culture flask, culture, ultrasonicate, feed to c elegans at 14 c elegans dishes,
$280
Thats $1920
The MIT student is $ 1280
The remaining money could be used to find out if the two or three most longevizing yeasts, with their broth decanted into each other cause a second biotransformation that puts another moiety on the decanoic acid, centrifuge and do solvent extraction, if possible, feeding it to c elegans to find out if it causes greater longevity than either yeast alone. Then, use UV light on the caprylic acid transforming, longevizing yeast to generate mutants, culture at 7 separate UV flasks and then quantify any c elegans longevity gains from the modified yeast
There may still be enough money to expose 7 yeast cultures at different flasks to UV light until 1/100 are alive, regrow and create 100 millions of mutants, it is possible then with 63 c elegans, 9 per culture dish unless probing functions better with 3 per culture dish, probe the c elegans at day 33 on, to find out if the mutants' 1/100 fraction of the bio transformed caprylic acid has the heightened efficacy to cause greater longevity;
At the varied commercial yeast cultures probe c elegans at day 33 (30 days unengineered, doubled longevity from gene therapy at 60 days is published), days 34, 36,37,38 39, 42, 44, then every 24 hours; day 38 is 24% longevity heightening, day 45 is 50% longevity heightening
if the c elegans live more than 24% longer generously write to 100 mouse researchers asking if they would like a complimentary sample $100
Sake yeast, 4 times the hydroxylated ethyl alkane than regular s cerevisia
Not at the $5000 genetically modify a polyorganism broth of yeast derived from dirt sample sent from moist warm climate or like like Florida grass clippings, transform it with green fluorescent protein, perhaps without a protocol, although there may be one online the GFP will gradually accumulate making the most longevizes the most light emitting
GRAS food flavorings like heptyl esters are food flavorings that look almost like 10HDA
Caprylic acid C10, GRAS, could be fed to fluorescent yeast broth, flow cytometry might find a yeast that put a COOH group on it, the longest lived yeast would emit the most light; read up on if UV exposed yeast with mutations are still automatically GRAS, they might be. Noting just a few hundred yeast species and millions or more mutant yeast 20minutes of flow cytometry could find 99th percentile of longevity at millions of yeast or motr
Use a flow cytometer that lets the user divert the yeast to a flask on the side, so the most longevized yeast can be cultured, if it is a 300 yeast commercial variety use the microbiology lookup book i used in college or software to find out which one it is and order a fresh culture, or, better, and I read it is OK, culture the most light emitting yeast with other yeast until non fluorescent variety is produced, culture 11 flasks of those then matrix batch them for about 4 separate sequential hplcs then you have OK yeast that produces a yeast longevizing decanoic acid
Culture the yeast with caprylic acid and do hplc on one sample $370, possibly complimentary at MIT student
A different version of this that is particularly thrifty, Carolina biological supply has bacterial GFP transformation kits for about $60, you could find out what it does to yeast or you could find out what it does to 60 different, widely varying bacterial species, the bacteria might also do bio transformation, culture the most light emitting bacteria out of 100 (dilute bacterial culture to 24 per slide so you can, possibly, isolate the most light emitting ones or do flow cytometry on billions of them, it is not known if flow cytometry with a UV light next to it is affordable but it could be complimentary to an MIT student, culture and concentrate and dose the c elegans
$720 60 cultures, $120 media and flasks, $300 flow cytometry, $200 c elegans and 70 dishes
Suggest life extension use their affiliation with insilico genetics automated c elegans screening to verify efficacy at making c elegans live longer, then get permission to tell others about the results, that way cloned email letter to 100 supplements makers can be generated
The dyson company could make noiseless at the light coanda effect bathroom fans that operate automatically about twice a day even when no one is around
Longevity technology
I perceive I read some kind of emterosorbent made some sort of organism live 43% longer, yogurt is popular and thick, it is possible that a yogurt that is 4 ounces of emulsified enterosorbent at a cup of yogurt could be quantified at age batched marmosets as well as mice; kaopectate and alumina gel antacids (i perceive one of the enterosorbents i read about is an alumina gel) (aluminum has been linked to nonwellness though) taste good so it could be functional; one thing they could do at mice or pigs is find out if three times a week is sufficient to heighten beneficial longevity effects;
Mitochondrial uncoupling sweetener, I read online that NR nicotinamide riboside causes greater wellness, it also makes humans less strong perhaps because it causes mitochondria to change their form to lots more tiny mitochondria; a person online at imminst.org / longecity.org may have said their plan was to make many more mitochondria per cell, then cause them to be much larger with a high fat(?) Diet; they also linked to a reference that said that at the rat NR is digested into separate nicotinate and ribose, so the person tried taking them as separate ingredients and was less strong, as NR would do; it is possible the larger numbers of tinier mitochondria is linked to mitochondrial uncoupling, which at gene therapy c elegans doubles the lifespan; it is possible that ribose alone could have a longevity effect, a version of ribose that looks like sucrose might taste better than ribose; sucrose is dextrose connected with an acetyl group which enzymes at the small intestine membrane deacetylated, it is possible
Ribose acetyl dextrose
Ribose acetyl fructose
Could cause ribose to have a much better flavor, they could test this on age batched mice to find out if there is a longevity effect
Yeast live 400% longer on salicylic acid; screen a library of a million salicylates at yeast to find out if there are any that more than double that; the longevization effect at mice, i perceive was single digit; they could find out if the 99.999th percentile of longevization screened at yeast has an effect at human cells and tissues, notably stem cells, and things like cartilage, particular cytotypes might make a difference
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I saw a math equation once where there were some actual equations and then what I think of as an arbitrarily higher focusable arraying of distinguishable objects, the more times you did the leading sequence equations the higher the resolution got like a vector graphic, using that math as as guide to the optical like topology of the casimir flashlight as coating as light accumulated and twice reflectivity occurred the resolution of the vector graphic would heighten
If the Gödel Escher Bach light cube was actually a different shape, and every face was a vector graphic, the two reflections that cause the images to be right side up and right side right would reach the parabola coated with casimir flashlight from the math topology the leading equation part would always have the time traversing the parabola be utilized to magnify the details whether you went near or far or viewed at an angle the vector graphics resolution would always be higher than the cube
Could that also be utilized at each node at the network to make the kinds of variability that could occur have a so travel,
I think I should think about how to make the network of all the things a girls kindergartner does like goes near her friends and talks with them, how she does certain things at certain times because of the teacher and how to optimize thatp
Should the casimir flashlight coating build nodes faster than the nodes can run
A thing about theMWI is that because there are, i read,more branch universes than the source universes and they all make casimir flashlights with some multiple of casimir flashlight output that is used at the multioptimal network does that make communicating MWI universes (like overlapping MWI) does that give the capacity of the casimir flashlight at the source universe the ability to make more light, if so then the casimir flashlight can make more network nodes, arraying them at nonsaturated topology, than the network, at any velocity can saturate, the benefit is that thinking of kindergartners at kindergarten they are so saturated they ignore things. Some of the time rather than seeking the higher and higher vector graphic detail that PLLs their output, PLL bringing the ability to be on specification sufficiently to have a mathematically optimal output (perhaps one nonsentient node is making new vector graphics being informed and valenced from the other nodes) so that kind of originates optimality
To produce optimumness if a sentience does something benevolent or filler-like at the network the nonsentient nodes have numerous mathematical constructions, the sandwich theory of calculus with internode connections that create math noting the multiples of output of the casimir flashlight, and making nodes at a connection topology at higher velocity than they can be saturated if the sentience has any output to the network, mathematically because of the connection topology of the nodes the sentiences behaviors will always be less than saturation as well as greater than nonactivity because of the sandwich theory of calculus
Is it possible for a network to be optimal if the sentience is only partially attentive; the nodes store utilize and transmit data, transform things, replicate and recycle, depending on the sentiece, and the variety of nonattentiveness it is possible to use true neutral voluntary stimulus to cause a behavioral tropism at less than the threshold of awareness of the sentience, if the network notices the sentience has noticed anything then the stimulus thought to be neutral ceases occurring and a different truly neutral nonperveptible stimulus is utilized, the MWI could have accessible either what the sentience is likely to like, noting it can be encouraged as a tropism absent ever reaching the consciousness of the sentience, or, there could actually be a transfinitude of true neutral nonperceptible stimulus as available MWI data, if the sentience remains inattentive then the math of (is, is a different thing, did not think to participate, had not actually heard or thought of participating), the network is nonsentient, so the math concept of not in use or I have not read next years textbook yet have a math space. I will find out if I can do better than that as I am thinking optimum networks go with continuous math functions, thinking about optimal networks of kindergarteners
Another opportunity is making the math space the network is built at and built of is to find the math system that makes iterated function compression take as few or fewer steps to compress as it does to iterate, or at topology or geometry, simply look up a graphic or utilize an equation with a noniterated solution if you like you can record everything on the internet, find a tree with trillions or quadrillions of leaves and pack it into a human rememberable number sequence, that when a function, cellular automata or something is repeatedly applied to it the data string grows and after a number of iterations the original data, the entire internet is produced, what I perceive college professors and Microsoft found out about this is that it takes a bunch of computing cycles to compress the data tree to seed and equation or cellular automata action table. I think that it could be possible for a person to ask a mathematician "i heard there are noncommutative algebras and that factoring in them is less easy, might take more steps, or sometimes comes up with a big plurality of solutions, looking at it the other way is there such a thing as a hypercommutative algebra or topology where factoring is many times easier and uses fewer operations" note the hypercommutative algebra does not need to be supportive of the rest of known math" then the mathematician says well actually at a completely equational treatment of the 4th dimension it is absent possibility for a knot to stay knotted, the extra movement coordinates make it just slide apart, a topology that causes hyper commutation might actually have less than three dimensions because you are changing the number of state spaces available so there are a different fewer number, one thing that might function is a new fractal dimension between 1 and 2 or 2 and 3 like 2.7
The simplest kind of a casimir flashlight is just an array
Fun thing: a protein that makes a bunch of spaced fins so the space between the fins is the right size to generate casimir effect photons, electrons and even atoms, as a dry heap, at half the volume being gaps a kg of the protein would generate I think, a measurable amount of photons and electrons. There are many ways to produce this, visible photons could be produced
A casimir effect frequency doubling crystal with lanes of space at it internally could make photons then double their frequency
A puffy banana shape with a chamber, or line of chambers in the middle would light up the chambers interior to the puffy banana chambers and a sqiggle banana with a TIR surface and a refractive index could cause the photons to travel the gentle curves, even leading multiple curves to a most lit up chamber § ¿? …
A different thing was is the casimir output of a cool stellar mass, or a just less than fusion mass spaced out so it makes the most casimir photons and electrons possible
if 27 blobs on sticks all point towards a center do you get more casimir effect, does a pile of jacks with more tips generate more casimir effect, what about an atomized spray of quantum dots or a spray of dendric polymers with an omsimi Os at the center and 7, 8, or 9 lines coming from it
The parabola with the upper reaches at a wavelength larger than the diameter of the math topology it happens to be at heightens as the topological universe expands
The mathematical shape that would make the superposition of a minimax curve be planar is at the center of translation of each node at the network
even though minimax is like two u shaped things stacked, this might be like a Mini bowl fore each node, there could be a different, or function combined minibowl for each node, like a physical bowl for location
Could an electron minibowl at semiconductor technology, like at a laser diode, cause electron concentration that minimizes stachasticism and makes higher frequencies or less jitter possible, could electron mini bowls function as higher resolution capacitors with narrower specifiable output,
At a physical matter system could the two u shapes stacked or the sides of the
It you think of stacked U shapes, one inverted, as a minimax curve or bowl shape, with the gap between them less than the leakehage size of the atoms as petals then energy specific particles shape of each egg cups would have two different atoms anemeter scoop radial array is better if it is a globe-like 3D array of bowls (or minimax curves) with different atoms piling up, concentric plates of these (like candypanned sequential globe of anemoment coatings could pile different kinds of atoms or at nanotechnology, partially assembled shapes, if the nanotechnology repeatable building units were like T and [] and (), they could each pile up at optimal concentrations near each other
Breathsavers at base of bowl or minimax curve
Minimax curve inside a bowl, minimax curve with
Air popper popcorn maker with the warming motive air coming from the electrode like, breathsavers like, atom motionized and charge maker at the base of the mowl or the middle of the minimax curve
At a mathematical topology using the equations of 4D or 2D completely spatial topology are there more things a bowl curve or a minimax curve can do, or is there a completely new thing where the 4D causes a new spatial direction of favored velocitization or concentration, it seems like 3D would have
Bowl shaped and minax curve expansions at different spatial dimensions
1D,
2D, the available travel directioms vary distance travelled and velocity on the Y axis, and distributes items spatially on the x axis
At 3D, usual bowls an minimax curves with z-axis effect at bowls and minimax curves from y axis increase
At spatial 4D it could be that a completely new spatial dimension, which i might have read is sometimes called kana is produced, that gives the ability to make bowls that concentrate kana while ignoring z (high sides in kana, null length sides vertically (Z), or adjustable z sides in kana with zero x length, is still a bowl, that reminds me of a kind of tall teleporttion scan line (kana y and z bowl sides only) that if you physically moved it would traverse a person and teleport them to the different kana location, at an x,z, kana Bowl, spatially flat panel that if you put an item with enough energy at it gets out of the y and z and kana only bowl then traverses kana, if you made one then high energy items would teleport kana distances at 3D while remaining at original height and depth (the trajecories original travel path, specifying the curve equations at all 4 dimensions would make a bowl (a bowlful of teleport distance), or an acceleration region that moved things away from the center at a 4D minimax curve
1.2,3,4 with spatial D seem, to my perception to have a thing² amount of greater areas of effect like 2d looks like a U or a ^, and
Without gravity what do bowl curves and minimax curves do, well it is math so you just input the energy numbers at the equation as you like, it seems like bowls and minimax at popular culture just want to move to distal locations or gather at the middle of the bowl from unmentioned gravity, where every input to be calculated is actually a minimatrix or 2 element array, at floating point numbers the attraction or repulsion of any force at the 3Dimensions of the curve, like a bowl, cause movement effect, and the kind of static object new location use of the bowl curve equations are accomplished, and then you know the new location of the object, there are other applications as well, the varying acceleration of the object (Calculus) could be as interesting as where it goes, can you minimax a new idea or trend (hyper popularizing or hyper rejecting, noting that the same idea can be stated as its direct form or, sometimes as s rejectable that build something beneficial if the rejectable is beneficial todistance oneself from) and do different actions, media, or even locations have different minimax curves, or at a bowl, maintenance and continuity of a preferred thing are automatically reinforced (tropism to bowl curves initial x z y coordinates) unless the energy is so high, and at an application this can be benevolent beneficial energy, that the item gets out of the bowl, notably bowls actually select for propagating large qualitative, high amplitude changes while minimax curves actually select for least extraneous variables like friction or anisotropy of a field, so minimax separations, accelerations, and higher distance between origin and object is mathematically related, and equation-friendly, to easy changes of any weight
(What if you use a matrix of greater than 2 items at a bowl or minimax curve, perhaps sometes partially considered as a bowl or minimax curve with gravity) [G, weight], like a 2 times two matrix or a three times three matrix, then at another system of equations, or possible a curve made up of something differently curved than a rotated parabolic spline (bowl) or a stacked two units of parabolic splines of different ±ness,
Thinking about the way minimax curves utilize ±ness as part of their curves mathematical topological identity, could there be a three or four directionality of topological space variation greater than ±ness, possibly the (1i)+7 two component number could have a source identiness at curves (although, things being what they are weight or energy at stationaryness at origin is qualitatively different than curve traversal) so like the actual curved D object would look completely different if the curve math were based around the (±i with ±weight) variable form, I am reminded of the soil triangle with curved sides,
I like continuous functions but there is the possibility that presence or absence of functions causes a discontinuous function at A three or four curvature form, discontinuous functions, to my perception automatically instantiate being able to make a boolean logic math space
New to me is that a transistor on/off boolean logic is two state while the three or greater attributes of a new capability and attribute enhanced alternative expansion to bowl curve and minimax math curve has attributes as well as possible benefits, simultaneous general math awesomemess and actual applications, thinking of optimizing a network, the greater ability to heighten coherent-like behavior and be on-specification from less possibly spurious data or out of context operations has a noncoherence and spurious data preclusion that comes from having a replacement for a bit, or an extra bit, at every item, and, at those networks with data (like although kindergartners and their voluntary networks can be measured, kindergartners are different than, and qualitatively different and greater than just data), with the data at data transfering networks, curve topolgies that surpass minimax curves and bowls are three or four state and that ±i as well as ±weight at a number as attributes would have 2^2 (2²) as the base number of bits as its computational unit, and that zero has on one bit, the empty set has zero bits, a number like 2 has 4 bits, and a number like i0+2 has 3 bits and 2i+1 has has 5 bits, notably this is different than the number of bits at an integer at a bowl math curve or minimax math curve
So an application is this, if you have two systems with three state weight variables the ±amount complex number compont (3i), or Even just presence or absence of a complex number component and a ±integer weight as an application you can make a containing, with accelerative spread (minimax curve) or additional new attribute curve that contributes weighted items to the next, possibly triangular curve in the stack (rather than just grab the three attributes make a triangle it is possible a location tropism at a bowl you can accumulate numerous separate items of different weight
Two different math curves (niftier than bowl or minimax curve), bowl, or minimax, psssing traversing numerically weighted objects to each other, at some positional relations but not others (edge to edge dimers or meet in the middle of the bowl (makes everything from a )( to a two sides of a bowl omitting bases make a tube that gets traversed, absent gravity the new gathering area might be the middle of the tube which has the new attribute of being right at the vertical-like center of the two curves, aimimax vurve stacked on another would create a different mathematical space, with height effect on the weight having anitropy with the tall side connecting the upcurves of one with the upcurves of the other, without energy change at the weigh, but at gravity versions. The possibility of being with a rotation variation of linked rampswith the anitone curve inverted does a different thing)( dimers are anitropic, and stacks are height polarized but functional), >
At two stacked curves you make a new kind of binoast, or if you prefer a weight classifier, possibly much more efficient than some other weight sorters
Sutomated generation of things better than Turing machines, noting 0,0,1 automata, tree automata,
Deep learning ai looks at first million or billion generations of all the n-rule automata,like 0,0,1 where their combinatorial generative space can be computed in less than a month, possibly the first trillion distinct rule seys, at 700different, identical between ruleset different initial values, at some automata there are nstates per cell (stay, make neighbor, leave)
There might be 2^4 (2⁴) attributes to a curve traversing weight with a complex number form, that means those curves could have 16 different things that happen with the travelling mass, hop up, hole pass, chirality, beyond 2 state chirality like 3 symmetry or aperiodic tiling,
What are new attributes of bowl or minimax curves with a complex number component
1D seems to generate math, like things have discontinuous ness without putting boolean logical or set theory at the math space, to make a bowl you day, no travel is visible, unless it isgreater than or equals 700, and if it is above a certain amount then it is like origin + 700 instantly, while at minimax curve it is like saying any amount >0 causes any amount from .1 to 700 units of travel automatically, these have a kind of instantiation logic where if there is a thing, it appears on a number line differently, and, or, not each come from different combined 1D curves or equations for 1D with a minimax inside a bowl or a minimax with a dip in the middle of it, making computers and logic new and replacing set theory seems nice and has utiltity
A modification to 3D bowls and minimax curves is with with modification (upcurved ski jump, or pour spout) the z direction can be modified from monoeffect z± changes or things move up sides of bowls you get ski jump or pour spout as well, it is possible a perimeter lip (ski jumps or pour spouts) could always make output that considered as a group have soliton shapely
Noting 3D bowl or minimax distal tips adjusting z velocity, adding y and x component perhsps a soliton shaped bowl of minimax curve can be produced. Rather than just a U curve, among them one ~~~ frequency valley and two peaks, you could have the two peaks and a velley a U is made from have a soliton ~~~ shape
or a U stacked, the U shape would be direction
Noting soliton shaped emissions from modified lip bowls and minimax curves, when considered as a group are output as a soliton, could an atom beam, directed at a double slit do a new thing with the lines of interference produced, perhaps it would just make tighter narrow lines but I do not know. Soliton shaped beams could have an effect on the traversal distance or highness of resolution at the delayed quantum choice eraser lengthening the duration of the amount of retrocausal time that can be produced or also making effects more precise
At 4D time you get motion concentration or spread out from bowls or minimax curves that causes time pooling (the 4th dimension) or timelines that velocitize away from each other, a possible green shift MWI technology that bowls concentrating cosimilars at the different universes or separates them as much as possible
Schoedingers equation version of MWI is duotree branches, other new versions of or replacements of scroedingers equations might have more simultaneous near universeses, making multiramps at the 4D bowl or minimax curve do parallel sorting, or even realationing
Thinking network optimization casimir flashlight that traverses energy or even data between MWI (from nested overlap MWI connecting casimir flashlights) could use 4D bowl curve technology to drawn content from most similar MWI universe causing less data variability and greater network predictability, supporting optimal network continuity of function
Can minimax and bowl shaped atom-composed sorting curves at nanotechnology function well enough at Santa Barbara california USA June 1st daytime temperatures to make concentrations of nanotechnology repeat units to make nanotechnology objects even though it is warmer than liquid nitrogen on earth's surface , then that would be a Santa barbara temperature nanotechnology that can build things
Similarly could a physical minimax curve or bowl, likely with energy ramps be a catalyst, the bowl or minimax curve could have an osmium, cobalt, or rhenium atom at one angle of the bowl's energy tuned ramo to do catalysis of molecules right at that spot where there was a concentration of ramped atoms
Nanotechnology atom sorter, only atoms of a certain size can take a particular minimax shaped petal energetic acceleration (minimax effect) actual physical shape pathways, also could a stack of mimimax curves, possibly with spaces between them, effectively filter atoms to each of a different angle at 360° as the atoms had the spontsneous energy (like charge), input energy, like voltage, or even stochastic autowiggle to travel the minimax curve or take the right pitch of ramp to get out of the bowl
The tir plasmid is
Is it possible to use a vector graphic of a lookup table, such that if a light wave is in phase it is modally processed but at phase deviation it gets trimmed a Planck length per cycle from a nondynamic material
Longevity technology
They can make many organisms live Longer like double lifespan c elegans, 400% greater lifespan yeast as well as some published
100% and 60% mice; I think they should feed the 400% yeast to c elegans to find out what happens, they could also feed the blenderized c elegans to the yeast
Rather than
(new note)
[NOTE 17] Nanoassembler and nanotechnology
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Sat, Jan 25, 2020, 6:25 PM
to me
Nanoassembler and nanotechnology
NOR computer logic form
Sensors
Transport mechanisms
Hamster balls ac like electret pulsing polarization, wind up clock with piezo hands strobes outer surface to repel and attract on U (actually O) segments, hamster ball can carry cargo
Bootstrap nanoassembler
SiO2 ic chip lithography isotopic electret paths, molecule sorting dot twister mats, mems or 3 nm vacuum huts, hamster ball transporters made with material that sublimes to leave an empty compartment, a Tetris piece maker, an annular vibrating circle that vibra-plate and/or radial isotopic electret sorts Tetris pieces into separate piles, then
Audi/olympic circles with an inactive one (or several) that turns on after the Tetris piece sorter has grouped the Tetris pieces, at the overlapped part of the next Olympic circle a blend of two Tetris pieces occurs, and their compatible electretness or mechanics sticks them together, piezoelectric or other motion jiggles them outward to another annulus, that annulus has electret surface patterns that favor a particular configuration and form to probabilistically attach and stay around even with jiggling, the overlap with the next Olympic circle can have electret patterns on it that favor uniting two groups of two Tetris pieces, there is also a piezo pattern that vibrates things on the previous annuluses back to a stochastic distribution so the Tetris pieces that have not successfully matched and travelled out of stochastic I at I on range have another go at combining
Another ic 3nm technology is to make a coil spring @, toss it on an electret alignment maker and cause it to change shape with piezo electricity, storing tension and mechanical energy (it is encircled or point-kept from expanding, then when the piezoelectric energy is no longer supplied or the coil @ is moved it can supply continuous mechanical power
Quantum linked photon communication UV sticky tape/peel, parabolic dish 3nm ic size
Pinball bumpers that sort and decrease stochasticism imparting energy to things that bounce into them with vase/face contours, high up get energized, vase/face could be improved with flexi-shingles that dampen velocity rather than impart velocity and reflect to be nearer the base electret surface, vase/face with shingles could be made with 3-7nm IC technology, a nanoassembler making nanoassemblers component could be making vase/face with shingles from Tetris pieces sorted with annuli
with piezo electricity makeable from storing tension and mechanical energy at the wound @, then when the piezoelectric energy is no longer supplied or the coil @ is moved it can supply continuous mechanical power
I think non-drexlarian nanoassembler are possible (notes), some drexlerian nanotechnology has possible new technologies and improvement
I saw a Drexlarian nanotechnology video and at it they had a bunch of what looked like AFM tips on the perimeter of a wheel, to have them do pick and place of single atoms or entire Tetris pieces actual AFMs modulate charge, that would at first seem to go with e- conduction pathways to every AFM tipped wheel but another way to do it is to have a tall chunk of piezoelectric material, taller than the AFM tip that contacts a strike plate nest to the thing being built, that pulse of e- provides the energy to glom or unglom the atom or Tetris piece at the tip, another possibility is to have the flat sides of the afm-tread wheel have a (circle of) little raised columns that are struck periodically (or programmatically) and then conductive pathways (or possibly just electrostatic charge distributing ridges) cause e-changes at the AFM tips to vary their glommingness, this is kind of like a disk (rather than cylinder) music box
One Drexlerian nanotechnology uses C2H2 to make diamond, isotope and spin effects of deuterium could cause more maneuverability and responsiveness to varied kinds of electricity like exposure to spin polarized electrons, published material says that oxidizing No with spin polarized O2 is 40% different
Doped diamond can be a p or n semiconductor, it is possible that diamond sponge could be nano manufactured, with the possible advantage that the edge of each hollow would have surface-like charge anisotropy, the surface charge anisotropy would make the diamond more reactive, causing the 0°C or STP growth of diamond at the surface to be more chemical physics favored, perhaps even with Drexler's C2H2 acetylene feedstock, spintronics does varied things with crystal lattice anomalies (hollows, edges), and different versions of acetylene (C2D2, or even C2DH) are likely to grow, or AFM tip place differently and with a wider latitude of engineering material characteristics
Sticky tape x ray diamond dust maker, the cover of Science had a light and X-ray emitting roll of unpeeling sticky tape, it is possible that the light came from a line of plasma produced from the minute area of "nothing there" (vacuum) making plasma, there are are 273 kelvin plasma diamond CVD machines, so perhaps a sticky tape plasma nanotechnology could make diamond chunks at varied sizes
Are there "endothermic" (cooling) physics "reactions", like throwing a tarp on a pile of dust, a dendritic tree with electret branches, inserting rebar into premade holes at a column that is swaying, these could contact another system to make it jiggle less (cool it) that could benefit nanotechnology, an AFM tip with an annulus of dendritic tree electret material like an anti-wriggle wreath at the base of a AFM tip cone could wiggle less
There is a little more to this endothermic like physics, rather than just damping vib there is the p
Grapheme net with hexanes between cycles could be a cling to fit tarp over a pile of diamond nanodust or Tetris pieces
Little edge and chunk disturbances in electrets make them last longer, and putting 500 nm chunks has been published as doing this, so making Gaussian or other patterns of nanothings could benefit electret applications, electret sides at Tetris pieces and at material and nanoobject paths could have these as internal
It is likely genetic algorithms to heighten the capability of nanoassembler is described online, a bootstrap IC wafer version makes millions or billions of nanoassemblers then the ones best at assembling things are found, studied, their capabilities concatenated and genetic algorithm screened again
Analogous to a monopole-like Halbach array, electret square arrays could have a very electret side and a non electret, even electron ignoring side (without chemically being Teflon), if either or both of these is possible then super slippery non-sticktion material and nanoobject transport paths as well as very-much-stay on it paths could be made with SiO2 electret (bootstrap IC technology uses lithography to make these enhanced paths) paths and Tetris piece sides
At an SiO2 surface perhaps a nano hamster ball or hamster cylinder big sphere full of power, eentsy line tread could make voltages sufficient to resurface, modify electretness of travel pathways
Carbon dioxide food maker and social companion robot maker
At nanoassemblers that eat rocks Aluminum hydroxide gel batteries chromotography at insulator then connect conductive pathways to different chromatography bands use separate chrmotography bands as battery chemicals, thermoelectric, photovoltaic TiO2, sand dune collapse avalanche electricity, nernst battery arrays (chromatography and concentration) Fe3O2 ->Fe2O3 generates electricity, these occur in rocks, bacteria can live off an iron oxide cycle
With a Nernst battery evaporation can produce the separate values of ion concentration, if drexlerian acetylene to diamond makes warmth that could actually drive the Nernst battery, which uses water as a place to have the ions
At crystals phonons and plasmonics has to do with the.patterns and movements of holes in a crystal lattice, kind of reminds me of proton conductors, physicists could find out what the biggest plasmonic hole they can make in a crystal is, computer models could then figure out how to stimulate plasmonic inputs (likely but not necessarily at the perimeter)
Possibly Sponge on the exterior, plasmonics then travelizes the missing nuclei to designed locations in the crystal, making Tetris pieces from novel cleavage (custom shards), or making detailed hollows as mold forms, pallet nest tool/object hollows,Making the largest plasmonic hole could benefit thermal/jiggle management as well making shock absorbers and even dewar flask (thermos like) hollows,
Physics researchable, if you use just 1 or 10,000 photons at a detector can your optical path be much smaller than the wavelength of light, nanoparticle suspensions like Fe2O3 have color, are they reacting to wavelengths thousands of times bigger than they are, or kind of amusingly, are 1000 of them just lining up in solution to make a big antenna, IR spectroscopy of water and conversion of AGNO3 into silver from light suggests triatomic sizes of photon detectors are possible, if these can detect quantum entangled photons, causing another of them to identyize like New Scientist quantum camera then nanoassembler and nanotechnology could have data communication without light wave sized optical paths
A dense chunk, a beehive with frames, or calm worlds in a a feedstock refreshing fluidized bed, calm worlds at a fluidized bed might get continuous piezoelectric power from their exterior
Also, the antenna compared with Ag ion size difference, and the Fe2O3 nanoparticle solution having color even though i think the nanoparticles are smaller than a wavelength of light and quantum dots emitting at wavelengths hundreds of times their diameter, all make me think em power transmission can be done with a nanoantenna thousands of times eentsier than a wavelength of the EM energy
read about coherent warmth (different than IR)
What might work is a big area capacitor with electricalal connectors hanging down from it at part of the nanoassembler, also these are macro enough IC tech 7 nm conduction pathways, I am reminded of compressed air tanks with hang down places to connect pneumatic tools
Quantum dots on stalks as local energy harvesters, perhaps even though there is a huge wavelength mismatch they can absorb "coherent heat" that I read about or IR from it
Electrets last multiple decades or I think longer, it is apparently possible to recharge electrets without melting them
It is possible a nanostructures electret could
A flying (travels independently through gas) inkjet printer from human visible drone to nanotechnology, nanoassembler size
Quantum camera lens could scan a bigger thing at 3d then the other optical path could go through a shrinkifying lens to make a miniaturized image, like making a miniature figurine at AgNO3 gel, different than nanotechnology, at nanotechnology possibly a larger IC technology object could be quantum camera shrinkifying lensed into changing a nano material to make a shape, circles, curves, and things beyond Tetris pieces, that this can be done non-aqueously is suggested from the existence of solid phase batteries and solid catalysts, these suggest the write medium could be a crystal, or an orderly heap of nanodust, or a roll of bubble wrap
Trampolines of frequency change, along with vase/face with optional damping shingles that adjust the 3D form of a velocity and angle distribution I think it is possible to increase or reduce the frequency at which something jiggles, moves or rotates, these could be used at nanotechnology, a merry go round could use centripedal effects to make all the things at its perimeter wiggle ( linear translate, but also stochasticize differently) less, I do not know why a rotating penny at an angle to a plane makes a higher and higher frequency sound but that is one way to heighten a frequency, perhaps it still works without gravity if you have the nanopenny spinning on an attractive gravity replacing electret or an orders of magnitude higher attraction electrostatic voltage clamp, also if you put a pole or tube on just the upper side of a rotating penny-at-an-angle then the pole sswoops out a cone and is sort of like a continuously varying gear, with the top of the pole the widest radius gear, and all of the pole or tube where the diameter of the trace out (spline) is less than the diameter of the penny is like a gear smaller than the penny, this is kind of like a gear with one tooth, but if you like you can put a circle of tubes on the penny and make a variable multitooth/peg radius, and gear-for-ratio gear this could have value as an adjustable frequency (higher with option of less frequency amount) rotating motive power source at nanotechnology and nanoassemblers, after it winds down to lay flat a nanoactuator could lift the penny with tube back up to about 89° for it to rotate again
i have seen images of nanotechnology gears, which with gear ratios is another way to do something multiple times faster like flinging bismuth diamagnetic mold releaser onto tetris piece molds, predictably rotating a drexlerian AFM tip nubs on wheel as a perimeterized atom or nanoobject placer or at more gradual velocities using an AFM tip to actually break apart a molecule for materials
some systems automatically geometrize (the shape causes the effect) to have a fast and a slow region, computers could do something with Milliken oil drop levitating nanopowder reynolds numbers, a fluid travels faster in the middle of a pipe than the sides, if a nanoassembler wants to get a feed of some kind of atoms or nanoobjects at some velocity it could tap different areas of a pipe, this might or might hyperbolic paraboloids
Big chair/boat conformation molecules, optimally inorganic (Boron, Silicon, sulfur) benzene, not actually a gear but has possibilities, shift between a 3D crinkle boat and chair shapecrown ethers
At a travelling nanohampsterball
Inorganic Silicon polymer liquid crystals might be possible, twist and untwist, lengthening, also stiffen for better levers, it approaches being chemistry but one distal tip could have lots of charge or a dielectric paddle on it so it sticks to something it is levering, alternating current-like thermoelectric electrostatic things are previously described so it could glom when it wants to push or pull and go neutral or repel when it wanted to move away
Also Si liquid crystal Shock absorbers
Network theory have process at an intermediate value that you can velocitize or slow, so if you are nano assembling on a turning merry go round you can slow the merry go round, which uncompresses and causes things to spread out more when they jiggle, or speed it up to reduce stochastics and reduce the spontaneous travel length of material
As a human visible and hearable thing, Rotating Penny with acoustic pitch raising at each of a group of disks of sizes that make compatible notes together as their sound moves upward, a new to me thing
(new note)
[NOTE 49] At the 21 st century there was a kind of material known as plywood, and it seems like genetic algori
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Wed, Dec 9, 2020, 8:45 PM
to me
At the 21 st century there was a kind of material known as plywood, and it seems like genetic algorithm (math) optimzation of new new plywoods to be variously more durable, more on -true and even quieter are possible, the internet did really well with this one and a bamboo plywood got 23% better from genetic algorithms math
Plural and depthy and, if the retrocausauls are supported arrays of delayed quantum choice erasers that are made with genetic algorithms to be much more technological capable and include an optical computer component are suggested by the Nature artiçle https://www.nature.com/articles/s41598-018-29275-z the article also makes me think of using GA to make really precise Evansescent and forbidden zone light steering like the wax prisms and microwaves thing I read about; I'm probably just kind of of confused but it is sort of possible both the semicocoductor masks could have higher resolution and with micropatterned forbidden zones being micro detailed they could actually get to produce smaller feature size, but I am clueless
I read about how adding alumina to PTFE can make it five orders of magnitude more resistant to wear, GA are used to generate new polymers, " Evolution of polymers by natural operations of crossover, mutation, and selection over 100 generations leads to creation of 132 new (as compared to 4 already known cases) and chemically unique polymers with high T g and E g.
" that suggests that generating 132 or more new polymers for bearings is a rapid process, and that these non fluoro polymers or also fluropolymers could be tested with alumina to make better
Heat pumps are an energy efficiency technology around 2020 AD, it is likely they could be much improved and even posiibly replaced with heat pipe technology, " An integrated heat pipe cooling system has been proposed to reduce the energy consumption of cooling system by using natural cooling sources in our previous work. However, it still has huge energy-saving potential in the operating process. In this paper, the heat transfer model and energy consumption model of the integrated heat pipe cooling system was established to describe the relationship between operating parameters and energy efficiency. Based on genetic algorithm, energy efficiency optimization operation strategy was calculated at different load rates and outdoor ambient temperature. An experiment was carried out to verify the accuracy of the optimization algorithm. Compared with the previous work, the energy efficiency ratio of the integrated heat pipe cooling system can be improved by 2–3 times in natural cooling model and integrated cooling mode after energy efficiency optimization. " the 2-3 times GA improvement is really a big cooling improvement
It seems possible that Ga that new kind of solitons could be developed, I have heard of a human based kind called a dissipative soliton that is 100 times longer lasting than a regular solution, so GA that genenerate a new version of soliton could go well with phone radio antennas that GA are are already known to be better at humans than making to make higher efficieiency radioes with fewer base stations
I suppose this is sort of just entertainment, although halback arrays have a varerity of published the number of different parquet floor geometries, and materterials is vast to address at an GA space; also and area that could contain a technology is a an electromagnetic hall back arraray, supopposedly not possible they seem very posissible at 1-3 parts that are electromagnetic per 100 with the GA directinging the much higher % of elelectromagnetivity at the new kind of hallback array
Longevity technology, a bat researcher writes about , Here we conducted a comparative genomic and transcriptomic study on long-lived Myotis myotis (maximum lifespan= 37.1 years) and short-lived Molossus molossus (maximum lifespan= 5.6 years) to ascertain the genetic difference underlying their divergent longevities. Genome-wide selection tests on 12,467 single-copy genes between M. myotis and M. molossus revealed only three genes cdc30 looks a lot like Coiled-coil domain containing 130 is a protein that in humans is encoded by the CCDC130 gene. It is part of the U4/U5/U6 tri-snRNP in the U5 portion. This tri-snRNPcomes together with other proteins to form complex B of the mature spliceosome. The mature protein is approximately 45 kilodaltons (kDa) and is extremely hydrophilicdue to the abnormally high number of charged and polar amino acids.[5] CCDC130 is a highly conserved protein, it has orthologous genes in some yeasts and plants that were found using nucleotide and protein versions of the basic local alignment search tool (BLAST) from the National Center for Biotechnology Information. FATE1 and MLKL) that exhibited significant positive selection. Although 97.96% of 12,467 genes underwent purifying selection, we observed a significant heterogeneity in their expression patterns. Using a linear mixed model, we obtained expression of 2,086 genes that may truly represent the genetic difference between M. myotis and M. molossus"
So they have what look like $70 f4ont/back baby wearables snuggles at amazon and 3-5 on alibaba, a technology that might work better on either of these are cool side of the pillow mini whiffle air passthroughs
Longevity technology C60 is published as making rats live 90% longer, giving 100x dosage IP of the oral version, once then transplanting unexposed legs to the C60 body would find out if something the body produces in response to C60, but not actual direct c60 causes longevization, if those are say protein drugs they could be made a bigger part of the human germline
longevity technology c60 as well as nanoonions have published effects, other lamellar hydrocarbons like those at lanolin or a new possibility, silicone lanolin polymer could be tested for longevity effects, many lamellar polymers can have natural origin, suggesting making and finding longevity/wellness/crop yield (algae) heightening lamellar polymers and placing them in ubuquitious human plants like evergreens for longevization/wellness/crop yield gains like c60, if a longevity lanolin is possible that suggests an upgrade to drinkable human hair grease water could be a longevity drug
It would be beneficial if the potency of the lanolin like human hair grease drug were 11 times higher than the amount one person naturally makes
At
longevity technology senescent cytes do SaSp, and senolytic drugs get rid of senescent cytes causing greater lifespan, similar gfp seno, parabiosisb, diff fp, what pb tissues rescued with what; make that stuff,germline
MZ twin 100 healing colony