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Longevity technology
Klotho is a kidney gene that makes mice live longer and be twice as effective at finding things when genetically engineered to make a lot of it , it is possible that organisms that utilize their kidneys and brains a bunch simultaneously could have more effective versions of klotho, dolphins, whales and sea otters are organisms that may have this feature from gulping ocean water and processing it, beavers might gulp a lot of freshwater and as they build things may benefit from higher cognitive ability, klotho could, possibly or possibly not, contribute to beavers living 35 times longer than mice, squirrels which have orders of magnitude greater ability at remembering and finding objects, to my perception, compared with mice I previously mentioned as Klotho gene versions, with possible optimizability, as well as slight variations on the gene protein product as a protein drug, a longevity drug as well as a variation as a protein drug nootropic
Longevity technology
Klotho external protein is mentioned as receptor less but concentrating at a word like sialogangliosides, that suggests sialogangliosides could be tested as longevity drugs and nootropics
Supercentensrians were tested and found to have about 1.5 times greater likeliness of having the most favorable variant of the klotho gene
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Eat 1700 calories a dayday
It is possible that eating 400 calories a day does not provide sufficient protein for dermal integrity, take multivitamin with food
Suggest maintenance look at water dripping through bathroom ceiling, repair winter warmer
Clean up before alerting maintenance
Rewrite deletion note
Get dasatinib and quercetin $100
Get deprenyl
Get AEDG Epithalon $140
Find out if royal jelly has effects that are beneficial a few minutes after ingestion to half a day later and possibly align royal jelly dosages to activities like science museum, early near sunrise energeticness, amelioration of the effects of other things,
Possibly socializing
Give Bob Ruthven some royal jelly explaining DHA and DAEE, I think he would like it, after figuring out longevity dose give him two weeks amount and enteric capsules, from the mouse study he could live 3.5 days longer, he may like the scientific paper so print out a copy to give him with the royal jelly
Emulsified royal jelly with food 200-400% the absorption per dose, also piperine effect when taken with the rapamycin and piperine, particularly at enteric capsules
Put up flyer at community college to hire a person for 1 or 2 hours to make rapamycin pills, piperine pills, as well as enteric protein structure retaining royal jelly pills, order more enteric capsules on eBay
Go to grocery outlet when visiting shama house and get vegetables, avocados, pears, see in Bob is willing to drive at a canned vegetable garnering occurence
Take a multivitamin, 1/4 the usual calories a day could cause undernutrition
Text bob twice a week
Bob mentioned writing a book, be encoraging
Find out if the positive psychology group meeting once a week can happen
Volunteer a bay area hospital of if possible north bend medical center
Donate money to high impact charity
Does GABA the chemical have skin soothing effects orally even though it does not pass the blood brain barrier, online it says it does
Donate money to SMART program but consider if books at some global location might generate even more enthusiasm, enjoyment and personal options, perhaps donate to developing world libraries
It is possible the perspiration that phenylethylamine causes has to do with itchiness, are there any harmless or even beneficial things that reduce perspiration
Convert imminst.org rapamycin dosage calculation post to a liveleak and YouTube video, likely a powerpoint video, it is likely that 1k-5000 people will view it on liveleak and noting the one click through per 1k internet banner ads 1-5 people might click through to ordering rapamycin on alibaba as well as the actual journal articles
Think of something actual and ethical to do that Dave would like like saving mammals lives,
Listen to the Pixies, find out if they have high utility pattern content like "what I leg activity before becoming a Pixie" then see if any of it happened since '80s-90's, perhaps they have a song explaining the effect of food, or various numbers, as well as things I am absent thinking about yet,
I tried writing with the phone in sideways mode. Perhaps in about 9 minutes I will have breakfast, I wonder how long before the phenylethylamine is functioning, usually it functions better if I skip food. I read some comics today, how about a comic
Should robots have superhuman powers like vehicle escape, rescue, CPR and first aid, I think so, also what about the comforting baby carrying method I saw on YouTube and Deep AI cooing to babies to make then cease crying faster than the 99.999999999th percentile of parents, MWI of babies crying suggest happier babies immediately is highly beneficial, person who grow to be well, happy, cognitively 3, 4, 5, 9, 10, 11, 20, 21, 22, 23, or twenty four times more intelligent than Treon Verdery, from babies genetically engineered to cry one one hundredth the 20th century amount is a beneficial human germline modification
Another superpower robots could have is photonic brain scanning with Deep water technology as well as AI assisted truth detection like Anbar's digital thermography that on repeat or varied questions I once figured out gets to 99% accuracy, there could also be new words in the English language for truth written or typed and true, spoken and true,
Some kinds of truth that brain scanners see can be connected to new words, perhaps phrases of truth like "there's more to it than" amazing, or "i do not have the words for it but it's like", or even just "like amazingly hypnotically beautiful", deeply felt truth, like if you feel a thing is beautiful but perhaps say "amazing", it is better to say "it is like amazing, but more", social companion robots and software could teach the new phrases, there could also be a more apt accurate use of " I'm getting", like "I'm getting an image", there could also be a lighter word for "important" like "in the field", " being on time to the party is in the field" one of a few important things simultaneously
Another superpower robots could have is hyperadequate balance, so you could go bike riding or lean on one for steadiness, or perhaps they could tilt a waterslide optimally, or stand on tiptoes, or suddenly catch a dish with a movement a 20th century human could not do
Another superpower robots could have is they could have the ability to always write and speak the truth
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are there 5HT (serotonin) active peptides these could be antipsychotics, longevity drugs as well as gene therapy
Some genes with a promoter attached to a luminescent chemical glow when the gene is activated, these can also be used to screen molecule libraries and I think I read about a few AMU molecule drug that causes more beneficial klotho gene activation that was found this way, a human has about 20k genes, if 20k, or perhaps fewer, multiplexed, different spectra of light emitters could be found then movies of a human tissue culture cytes genetetic sequentialities could be made, like something before klotho, then klotho, then genes that get turned on after klotho, one possibility is that attaching an 8 factorial peptide, where each of the mers of the peptide is a very highly differently charged amino acid could have stronger spectrum adjusting effects, another possibility is linking a variably -OH and -H glycosylated sugar to the light emitter, another possibility is at multimillion well plates or 10 million cytes per second flow cytometry to get a trillion luminescent bacteria, expose them to mutagens and plasmid recombiners like Ca++ and then have the flow cytometer have a spectroscope and place at side containers any bacteria with a new light spectrum emissions line, it is possible the approximately 67 days to screen a trillion bacteria would find new colors, a longevity technology application would be to movie map all the connected genes at the king's holly, the million year endolith, the nondefinite but likely longer than a termite queen lobster, and a comparison of mouse,naked mole rat, beaver, and bat, they could also compare human and marmoset and other primate genetic movie maps, movie maps of human oocytes being generated compared with 72 hour stomach lining and neurons could also be compared
Microfluidics have pumps, and perhaps there could also be a material that changes ease of fluid flow with a laser, photoelectric decrease of surface tension or bunch up or unfurling of polymer molecules that coat a microfluidic item to heighten fluid flow or gradualize it, I think I read there is photoactive polymethylmethacrylate, it could be outside silicone or other polymer microfluidic channels and do peristaltic pumping in response to light
Paint technology is it possible to use a laser to engrave a hyperhydrophobic surface (eentsy points) on the side of something large that gets painted like a bridge, a truck, or a ship, is it possible to put a hyperhydrophobic paint undercoat with decorative paint above it so as the decorative paint microcracks, chalks off, or wears away the protective effect of the paint actually goes up, i may have read that hyperhydrophobic coatings accumulate gunk, but once cracking, chalking, and wear away have occurred it may be a good time to repaint anyway, also they could have hyperhydrophobic coatings with much higher amounts of slightly soluble white TiO2 to make the thing become whiter even while the gunk accumulates
Another possibility for hydrophobic paint is not just silicone, urethane, or another polymer but silicone bilayers, kind of like membrane lipids these would attach more to the base layer with the highly charged head group, which could even be heightened with lasers at laser curing
Lasers making a hyperhydrophobic or hyperhydrophilic surface on things like bridges, trucks, and ships might be able to make just 1/100 of the surface engraved, but with fractal like fluid flow channels so condensation and thin after rain films run off, but the aesthetic value changes only 1/100th
Is it possible to make a paint that curls inwards if it peels, then gravity would omit pulling it off
Longevity technology daphnia have livers, they might have kidneys, klotho variations could then be screened on them for beneficial longevity effects
Liposomal Nasal sprays are published as effective at delivering drugs, could a version where some harmless gelling agent be produced that makes clingy-thick mucous be produced so there is an absence of runny nose effect, or could there be microspheres of PMMA, or another polymer like that 14 day contact lenses are made from that gives 24-168 hour dosing
Gdf15 gene makes mice live 44% longer could its protein products be tested as a topical beauty liposome or microsome, they could also find out what better genetic versions do for milk cows, extending their production
Well, i read some cartoons and comics. Some of them were funny.
Phosphatidylserine is an emulsifier, perhaps it would taste good if it had a ribose attached to it, or a sweetness peptide, PTS liposomal encapsulated emulsified omega 3s like algae oil would taste good and they could put that and other beneficial things in food
Pigeon feathers and the feathers of other birds could be genetically engineered to produce beneficial longevity drugs as well as other beneficial drugs, the white, blue, or green color of the feather and iridescence could be linked to what the feather drugs actually do to benefit people, this could also benefit the birds
I favor utilizing animals to produce pharmaceuticals as well as plants
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A new note, I suppose just like people who take psychedelics sometimes say they can see new colors it is possible there are musicians who say they have heard new notes, and there are animals that hear ultrasonics, perhaps AI could use a vibrator next to the side of the ear and notice when people had the FMRI of hearing a pleasant note but base it on some new group of notes, like I hear wind chimes always sound harmonious because they are non-octave, perhaps there is something new like that to be found, it is also possible that stimulating hair cytes at different patterns could sound different, it is different than head hair but if there are whorls or tufts some counterclockwise or clockwise stimulation of them might sound different, it is beneficial that all the new notes be pleasurable to hear
One thing that is likely harmless if accomplished carefully is cofocalized microspeakers making only the outer ear canal feel like you put a puffy tipped bud in them and twirled it around, it seems like lasers could measure vibration and the microspeakers use ultrasonic beat frequencies to generate the sensation just at particularly pleasurable locations
Longevity technology
Things that fill children with happiness
Expanded comfort zones, kind of like big five Openness to Experience, but there could be other entirely beneficial things, like
Fun playground equipment
People have varying oral senses of taste, without effecting body weight they could find the genetics of the ability to taste food, and enhance it so more things tasted good more often, this could benefit children as I think I read that some 20th century children did not like the taste of vegetables and this way they would like the flavor, there could be things besides fMRI of flavor and genetics, it is possible having 32% more of particular enzymes at a human mouth causes better flavor while the saliva remains flavorless, also this is different than feeling appetized
A probiotics or topical gene therapy that precludes body odor are things that would benefit humans, I think they should make them, also there is a published genetics of not having body odor
They could have software that texts a person once every 4 days, always on a different day of the week if they took their medicine and what time they took it, software could estimate when to send a text for greatest increase in voluntary medicine compliance, the text could say "just reply with 'more often' if you would like more reminder texts per week', I do not know how much increase in compliance this would create but 1-3% could be 1.5-3 million people voluntarily taking their medications more often in the US, it is possible that some people would be more avid if asked to make an image of their pill containers once every couple months, they could experiment to find out if sending a funny image caused greater compliance as this functions well with advertising, this could function globally as well, at least twice this year I have put off getting refills and missed a pill, pharmacies could text reminders, and, I suppose advertise something like vaccinations to cover the $ of the system and earn some, the person at the pharmacy could say "your slider bar interest in getting vaccinated reminds me to ask you if you would like to get vaccinated, would you like to do that now?", Also, yelp will autodial your phone for you, when you get a refill reminder text it could autodial the phone for you or open a browser page
Ask Fred Meyer if they will candy coat my pills
Today at the Charleston Marine Life Center I saw a plurality of nice people, one of them sang, and they seemed to harmonize when they talked, it was sort of non optimal (at least to me) that I interrupted their harmonizing with a few words about an exhibit at kind of a different tone than their harmonizing conversation with each other, I think they will have many good conversations with each other anyway
I think perhaps I should go to sleep, get a girlfriend, enjoy a thrifty yet delicious pastry, and order some longevity drugs online. Of these four things I predict two or as many as three will occur during the next 49 hours. All four seem impossible, but perhaps with fortitude, fortune, the wind at my back, and like, some women, this could be possible, also Bob and I texted each other about going to a place that may have pastries that are thrifty. So I am kind of confused, I do not know, I do not know, also I only know a couple lyrics to "Polly wolly doodle all the day", whereas I have even enjoyed thinking of new lyrics to "the wheels on the bus go round and round".
This having a girlfriend thing sounds great, and I saw members of the harmonious group kissing, the young woman had just graduated from high school, her affectionate boyfriend was sweet and frank. There is more to it than that, but, but, how to write it?
Theanine is a very mild relaxing drug when I take 400-600 mg of it, I know, I know, why not screen a library of molecular variants, etc. I do not know what the molecule looks like, but if I did I could guess at where to put the halogen atom,
I looked up something online today, and viewed some memes and ate an avocado and a honey flavored peanut butter open faced sandwich, I also read the comic Monty by Jim Meddick.
It is 9:30 soon it will be 9:32 then it will be 9:40
I have a no deletion policy where if I set it down for 40 minutes some could read them, humans, that is people are welcome to read my notes
After reading that royal jelly causes mice not to itch I mixed 2 grams of royal jelly with a few milliliters of isopropynol, stirred it and waited a while then restirred it, the next day I decanted the fluid and dried it at 170°F to make little clear blobs that were kind of gooey, then I mixed it with something like 1-2 ml of moisturizing cream and then rubbed the material that would not come off the stirrer onto part of my arm that did not itch but had a slight rash, it did not itch and there is no perceptible effect yet
Is prenatal phosphatidylserine beneficial
The lines are green, the text is blue, there is also lots of white
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If I had data on my phone I could find out what happens when I use speech recognition for several second several minutes even several hours it on but I don't know how to going to go
I have seen and eaten mulberries
I could have a big nap this afternoon
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Longevity technology
Are there any multicellular endoliths with 100k year lifespans or longer, screen endolith homogenates and electrophoresisized multicellular endolith chemicals on yeast
Do human epigenetics of the Gdf15 gene have numeric association with greater longevity, drugs that effect those epigenetics to produce greater longevity drugs could be multi generational
I read that fMRI can be used to map blood flow to brain region, I perceive it shows glucose activity, an article says,"highlighted blood flow to each brain region-a measure that indicates how hard the brain is working on the task" [going on] that suggests that a nootropic drug that makes neurons better at telling their vasculature to provide them with more circulatory flow like they are already somehow able to communicate to cause would be nootropic, or could be used to benefit emotional well being or be a pleasurable drug. I have not ever heard of people with high blood pressure having obvious cognitive or emotional benefits, and i perceive trained athletes with lower blood pressure than median to be at a full normal distribution range of mental ability, like Olympic runners, so, noting my perception of what fMRI measures and what the article says, the nootropic would be anything, originating at the actual neurons or even possibly circulatory system millimeter area, that causes the fMRI heightened activity, that from many many studies has been linked to particular brain functions to increase, whether it is "hair trigger" heightening of glucose or lactic avid uptake, or as the article seems to suggest, actual blood volume availability a drug or genetics that effects this could heighten g (like IQ), mental wellness, pleasure and happiness. They could do fMRI of different primates brains to find out which have the highest intensity fMRI, as well as find the 99the percentile of highest intensity fMRI (similar to contrast) and find out if the genetics of high intensity fMRI are mathematically linkable to anything beneficial, they could also look at persons at the 99th percentile of happiness (subjective well being) as well as the 99.9th percentile of cognitive ability to find out what their fMRI intensity and contrast range is, then they could find out if drugs that cause people to be at that range cause beneficial happiness and cognitive effects, there could even be a broader perspective, perhaps imitation wisdom pill that causes brain activation at different areas to be more similar to each other, so a high neocortex contrast, medium nucleus accumbens contrast person could find out if having both higher, or both median intensity caused new entire possible perspectives
like elevated heart rate with normal blood pressure
Have a fiverr person find some people more creative and optimistic and white than me, have them make suggestions on what I should do, include a mathematician
Things that fill children's lives with happiness
They could test new versions of see see o playmate to find out if new versions are funner, perhaps some reach up in the air (rave arms) would be beneficial
Well I find myself having nothing to do
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NDGA is published as causing longer lifespan, the G is gauiretic acid, related to the amino acid gaunadine, the could look at the electric charge on gaunadine and find out if any other ND-A chemicals cause even greater longevity, there are only 24 physiologically occuring amino acids so they could screen a library of all of them to find out if any of them cause greater longevity as well
Polypill is a pill that confers net benefit to a population, described as reducing heart disease and cancer, they could heighten the activity of polypill ingredients with things like halogenation, ethynylization,membrane transport moieties, and enteric coating, as well as longevity drugs these could combine to make the mg per dose 900-3000 times eentsier, that provides various benefits like making it 1/10 of a ¢ per dose or less as a pleasant tasting printed on paper drug, and the ability to put it in that size, shape, and flavor of pill most people find most palatable, if heightened palatability causes .03 times more people to take it then that is tens of millions globally
Make a new friend benches, I read that there are benches at public spaces that are labelled as encouraging conversation between strangers, I perceive from what I read that they are at least mildly effective, they could make a stroll around the park 4-7 item personality test kind of like the myers Briggs that suggests which of four lengthy benches to sit on, with "you can sit on any bench" prominently displayed, the benches might seat introverts with ambiverts, myers Briggs N with myers Briggs N, and extroverts with myers Briggs J, and myers Briggs J with myers Briggs J it would be beneficial to use a camera to actually study which people from the psychometric actually got along the best, this could also be an impromptu lawn amusement as well as a kind of thing they have at a Rainbow Gathering
Sometimes I think: I Should Be Gooder, and then I think of something good to do and then do it, not all of the time just sometimes
I have not thought about Douglas B Verdery recently, my dad, he was an awesome wonderful person who went on many adventures he was beneficially interested in and knew a lot of science and technology, along with his work as a computer programmer he assisted a physicist, sailed on commercial boats, flew airplanes recreationally, played guitar, sent me to private school which I think went well, and liked to write, I think he studied physics and journalism at Reed College, he really appreciated some human potential potentiating classes he took called LifeSpring, I miss him
They could study things that cause children to play more, then compare them as adults, if there is a kind of telescope that can keep being in focus as distal lenses or mirrors are removed that could be at playgrounds and have parts removed as they wore out
Optical coatings or ultra high hardness alloys could be placed at mirrors at children's playgrounds that could withstand weather, sand, and cleaning, even rear silvered glass with chemical vapor deposition diamond could be functional
Longevity technology
C elegans and mouse longevity could be studied at supplementing them with the protein the Gdf15 gene makes, then they could make variants of these proteins to find out if any of them caused greater than the 44% mouse longevity heightening from overexpressing this gene, the new protein's gene could be tested in primates then, if both harmless and longevizing, made part of the human germline
I feel alert yet placid, poised for action with no action occurring to me, no words to write or thoughts to think, I am even yawning
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Spin polarized phosphorescence with quantum linkage (entanglement) if it is possible to send a beam of photons through a beamsplitter to charge up two 72 hour or longer phosphorescent coatings and have observing the spin of just one of the phosphorescent coatings affect the spin state of the phosphorescence of the other coating, then the two coatings could be separated and placed at different parts of the earth or outer space and transmit data without transit time, the thing is though that at 72 hour phosphorescence you do not know when the paired photon will emit from its phosphor, 1 second or 72 hours, so if the phosphorescence of the molecules varies from a normal distribution of 300 phosphorescent atoms one million times a second, and you make a point of only observing up photons, then there would be a numerically quantifiable tropism towards up photons at the other phosphorescence that could accumulate to transmit data, this could be used to route optical data, transmit financial data instantly, and connect recreational internet users laglessly worldwide, another use would be to connect things like CPUs to memory or cache making ICs spread out over meters possible, providing cooling and possibly (possibly not) greater bandwidth
fMRI as well as positron emission tomography of women that get at the 99th percentile of sexual arousal when watching sex videos could be used to find areas of brain activation these women share, then neurotransmitter active drugs localized to these brain areas could be developed as a drug that causes secual arousal and likely better sexual experience
There is a brain map of where specific body parts sensation is mapped to when particular body parts are stimulated, they could make neurotransmitter drugs localized to the genital region of brain maps to make a drug that causes sex to be even more pleasurable
The brain map that has a brain area for each body part could be used to make neurotransmitter drugs that concentrate at the uterine brain map area getting rid of menstrual cramps, it is possible this could also be used to get rid of arthritis sensationMucoussilicoaminoacids I have read about mucoproteins they make things gooey, would using silicon based amino acids to make these cause slippery solids perhaps deliquescent that always stayed wet, what about halogenated mucoproteins would they be slipperier or make things slippery with fewer mg, could a person or computer compare the amino acid sequences of the slipperiest mucoproteins and make new ones that were even slipperier
I read that mice frequently get cancer could they breed two kinds of mice, one with lower prevalence of cancer than humans and another that almost always got cancer, then they could compare the different mice' genes gene protein products, and immune system sensitivities to find out if any gene therapy, protein drug, or immunization prevents cancer or cures it at the cancerous mice, then they could find which genes, proteins are similar at humans then find out if they are effective at preventing and curing human cancer
I read about a senolytic longevity drug that is also an anti cancer drug, could it be possible to measure a reduction of cancer at people given the senolytics drug periodically for longevity purposes, at humans an anti-breast cancer drug could be administered to just a few hundred age batched women from 19 and older to provide data on breast and other cancer prevention while also measuring longevity increases
I read that BCG TB vaccine causes 2.5 times less lung cancer, they could make a bunch of BCG variants and give them to mice to find out if any, or if revaccination mid life causes mice to get less of a variety of cancers, it is possible that if they test 200 overlapping vaccines on 800 mice they will find a vaccine at the 99th percentile of effectiveness, these could then be tested on humans with the 7 most prevalent human cancers being prevented at mice being a basis for preferring the BCG variant, also, they could make BCG variants from completely different mycobacteria bacteria than mycoplasma bovis
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Bob
Might like car event at coos bay motor speedway, shore acres - restaurant, I cover parking
Gas contribution
Hike further on airport trail
Reperatory movie like animation festival
Gallery walk
Art museum
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Toow gig microparticulates
Things that fill children with happiness
Toy that cause longer interval of play, they could see if legos of different colors or textures like pen crops (rubberized feels good Legos as all of them or in the mix) cause longer interval of play, they could test different facial expressions and styles of dolls, as well as different fabrics, some children put their toys in the same place after they play with them, if they made a doll stand with the words 'play with me!" It might cause the child to play with the toy more often or cause them to just play more frequently if the entire toy place had those words, a camera computer could notice when they were especially happy at play and then play very gentle music, linking the happiness to the activity, then the gentle music could play at different times of the day when the child appeared to the camera to be feeling neutral or less than neutral, behavioral psychology would be used to get the ratios right like 4-7 happy plays to one cheer up and play music cue, they could ask the children if they were happy afterwards on a sliding scale as well
Could hand sanitizer be enriched with happiness causing, cancer preventing wellness producing chemicals, an immediately rewarding sensation could also be beneficial, possibilities are cyanocobalamin, Se element (it is possible that up to 3-10-20 applications a day would be physiologically harmless and cancer preventing at 1mg each without a residue), folic acid,iodine,modified epithalon peptide (halogens, other amino acids, synthetic amino acids), thymosin peptide,as well as skin beauty and wellness probiotics that hands unintentionally transfer to the skin like the face are some chemicals that might work, liposomal or microsomal applications could be more effective,the probiotics could be spores, microencapsulated, or bred to reduce sanitization
Entertainment software that teaches children to smile when something good happens to them could heighten happiness, heighten happiness interval, and cause other people to have behaviors more favorable to the children when they smile
Some people exercise on purpose, among those that do, some perspire, a wearable fitness electronic armstrap that increases performance with chemicals, as well as transports longevity wellness chemicals could function with chemicals like the hand sanitizer chemicals, it is possible halogenated body side only (does not pass blood brain barrier) halogenated body side only variant on caffeine or halogenated one by methyl amines could function this way without raising blood pressure, research could be done to verify that these caused greater voluntary, even thoughtless, greater duration or intensity of the voluntary fitness activity
Could air filters moistened with a "magic rocks" solution or other gradual crystallization solution puff up over months or years exposing fresh filter surface with time, improving and sustaining filter effectiveness with time, even crenellating filter polymer strands that then gradually relax could make a difference
Cabin air intake filter on vehicles could reduce breathing of microparticulates
Could a very thick dental sealant, like 400-700 micrometers thick on back teeth dose people with beneficial nanogram active drugs, there is one published study of epithalon being nanogram active, although usually it is published as microgram to mg active, ethynylized sex hormones are a nanogram or possibly picogram active drug, and 17 alpha estradiol causes mice to live 19 pct longer, so ethynylized halogenated 17 alpha estradiol or chemical variants could be made part of tooth sealants(ten teeth with 14 mg of sealant each, is 140 mg, so 10k days of 10 nanograms of drug diffusion a day is just 100,000 nanograms, 100 micrograms, or about one one thousandth of the volume of the tooth sealant and provides 60 years of longevity drug dosing,
nanogram active, nondigested D amino acid versions of nanogram active epithalon could also be effective
At an engine or other moving mechanical mechanism a laser could project a grid of dots and either detect them with a lensed camera or a nonreflected optics quantum camera (New Scientist magazine) then another laser could edit the mass of the visible areas mass to reduce or normalize vibration from subtracting mass from parts, previously described as having a laser meltable alloy change the distribution as well as the amount of mass, this could also be used on electric car wheel motors and other motors
Are diamond bearings or the material found that is harder than diamond at Washington state university better, if they are then coatings of these could function at bearing travel paths
Different crystals take up different different amounts of room at the same number of atoms, if they put one crystalline structure at the core of ball bearings or other bearings and then used cofocalized lasers to make the core alloy change shape to either expand it or compress it (like prestressed concrete) or make it softer would this benefit wear life or load responsiveness, some ferrous alloy wheels have paper cores possibly improving ride smoothness, this could also have an effect on vibration pattern or even wear durability
Some lubricants accumulate corrosive chemicals, could bearings, like ball bearings have a lubricant that gradually plated a coating onto the bearing causing it to last longer, polymers with silver attached to the carbon, or a silicone lubricants, attached to the silicon might do this, harder elements like tungsten might do this as well
If fluorine comes in different stable isotopic masses then one variety or another of isotopically pure fluorinated lubricants like PTFE could have better lubricant characteristics
Retroreflective layers tune vibration, they could have differently spaced layers at bearings that cause vibrations to modally or antinodally concentrate at the surface or be reflected sideways and out to reduce system vibration
U shaped bearing fourier, I think think vibrations have fourior components as well as resonance frequencies, they could have software that verifies that a bearing and its load always have very different resonance frequencies, alternatively, if a bearing and its load have a resonance frequency then a half wave shape on purpose like ( could produce highly predictable center and side stress and the bearing could be customized to that
Fourier decompositions of a bearings load and predictable vibrations could find waveforms that cause smoother less amplitude shifting vibrations when added to the rotating load, the bearing could be enhanced to produce some amount of those vibration plateauing Fourier component vibrations
Stripes at cylindrical bearings, it is possible laser or micronozzle cold hardening or millifiore bead construction of bearings could make it so when wear occurs hardened ridges that can bear the load remain which have the advantage of linear performance over distortions from deformation or abradement
Things that fill children's lives with happiness
They could test different densities of memory foam mattresses at babies and children to find out if their much lighter weight made even cushier memory foams more comfortable considering a 3 Kg baby compared with a 70 Kg person
Ball bearings and other bearings
3D printed bearings polymer or ceramic or metal could be laser smoothed and liquid nitrogen miconozzle hardened
Some proteins quaternary shapes have a rotating axle could the parts of other proteins facing the axle be thought of as bearings and.made more frictionless benefitting physiological function, if they are already minimally frictional could that be a new low friction protein amino acid sequence to coat things like joints with, do these possibly low friction proteins differ between species, and confer different advantages
If there are low friction axle proteins, do silicon amino acid versions of axle bearing proteins have industrial applications
Things that fill children's lives with happiness
Sidewalk chalk you can buff to glossiness, buffing is kind of fun, a kit could even have an electric lollipop buffer, could buff to metallic or pearlescent
Sidewalk chalk that has a powder poof pad to make big areas and high adherence ultra washable chalk
Non psychometric thematic apperception test,TAT, where 99 pct of children perceive something good, variant version has a turn to a stochastic number the book generates then the child makes up a story about the two pages together
Sidewalk chalk with embedded gems that are scrape resistant, perhaps it causes children to draw more
Stickers and adhering gems that go on sidewalk, complementing sidewalk chalk, fully de-adheres and biodegrades after a month, agar gems, rice paper
Headphones could have soft internal polymer bands that are adjustable (like polymer robot hands) just touch any part of the headphones three times quickly to have the material adjust to relieve pressure on that spot for children as well as adults
Robots could have an extra anti-harm processor that filters all centrally planned motions and then electrically softens polymers(like robot hands)as well as has airbag option if it falls over
Things that fill children's lives with happiness
Software that teaches live-in boyfriends to be nice to children might work
Refigure the rules on the most frequently used boardgames that children play, quantitatively measure the increase in their happiness
During 2019 AD some children watched media, I think other things might be better but it is possible that show pairs or lineups could be constructed that are quantitatively measurable at increasing child happiness
Do audiophiles clean out their ears with a kit
Is there any kind of non circular wear that have any advantages like cams, perhaps vibrations in engines and other mechanical mechanisms
Depth peening of metal parts with cofocalized acoustics might be possible, this could work with bearings
If you attach a peltier element to a bearing, like a solenoid bearing does the cooling make it last longer
Doped diamond bearings might be piezoelectric and that could have an effect on wear or lubricant wetting
At polymer bearings could internal origami RFID shapes change frequency if the bearing deforms with one RFID reader per entire machine able to suggest preventative maintenance
Reminded of sequined pillows where if you stroke them with the grain they feel smooth I read that the fastest folding proteins are faster than measurement or 170 microseconds at 4°C could a ruggedized amino acid protein like silicoprotein with fluorine atoms on it conform to micro vibrations even dampening them causing wider area of rotator support and gentler more spread out point contact forces causing longer life
Other primates and multi century whale joint lubricants might be slightly different chemicals are any better than what humans have
I read that sometimes when a machine like a generator is next to another machine like a backup generator that is unused that bearings at the unused machine sometimes wiggle in place, often with less lubrication, that causes asymmetric wear, posibbly called brinelling that causes the extra machine to be less durable, they could 3D print polymer pads tuned to cancel out brinelling vibrations more effectively than other pads based on a measurement or prediction of the vibration source, they could also 3D print spongy washers that do this, a very cheap spongy paper layer between pallet timbers could also have tuned acoustic dampening, perhaps a plastic pallet spray could spongify pallets as well
Vacuum cleaner could have three full size suction holes, then if one got clogged the computer would notice and suction through one of the other holes, and they could use what might be lighter weight electric car motors or dental tool motors to create a larger number of square inches of vacuum under the vacuum head
Rather than square waves, could round waves overlap with really brief dips for zeros occur, if 1 or 0 is detectable 20 times faster than the other then data transmission would go up 10 times
Or amplitude modulated waves where a semiconductor photonic detector that is always on just distinguishes between more photons and not as many photons, running these levels near the threshold of detection might make faster internet, if you sent 1/9 more photons as separate multiplexed IP packets then it would be 9 times greater transmission speed
One extra or two extra wires on Cat5 wires would double or quadruple internet speed to the dwelling, could they deground coax and conduct along the sheath, maybe, maybe not
Things that fill children's lives with happiness
Pat a cake robot or touchscreen on media display
Vinyl colorform(tm) lenses to put on media displays and phones
Gecko feet thicker post its and bookmarks
Would fluorine atoms on a liquid crystal make an electrically adjustable lubricant liquid crystal, would making a liquid crystal with So rather than C make a more durable warmth tolerant liquid crystal
Pillow with long balloon core does not develop center depression, might or might not be cooler
Electret car wax repels dirt
Topical GABA drug reduces scarring,GABA drug soaked or containing sutures reduce scarring
There is a product called liquid bandage, dilute that and put fluorcorticoids in it to make dabbable multi day antidermatitis medication
Massage chair that looks deep into body and spine to deliver even more pleasurable massage
Topical skin decal with DMSO adhesive accumulates body chemicals over a couple days and color change antibody beads react to trace chemicals, the person makes an image with their phone and uploads it or peels off the decal and dents it to the doctor, anemia, circulating antibodies, bacteria or other things
Phenibut reduces my positive symptoms of schizophrenia, if there is fMRI or positron emission tomography correlation perhaps au audio or visual areas of the brain for each particular occurrence of hallucination at the brain then they could find out if screening a library of phenibut variations and other GABA drugs finds some that are more effective, phenibut about twice a week seems to be OK, they could also find out if the genetics of GABA receptor variants or endogenous amounts of GABA are numerically linked to less schizophrenia among happy, creative, prosocial happy people
Optimal height moveable poles for people to lean against
After coating medicinal pills could be acoustically microfractured for faster dissolve, this could be beneficial at analgesics
Could electret polylactic acid (PLA) be possible or electret sugars or dextrins, attached to spices and flavors these might have completely new tastes
Are there any plant based electrets that could be attached to flavors protein or amino acid crystals
A robot could give you a sponge bath and a massage at the same time
Floor and ceiling mount IR lasers could beam optimal warmth onto a human like just after a shower or having nude houseguests
Yeast that turns methane to food could be genetically engineered making food anywhere or also from hydrocarbon deposits
Nerf whiffle bat strikeable is harmless two ways and makes an attractive vase
To reduce risk to humans, veterinary nonprimate gene therapies could all be verified as harmless to primates, and could often benefit from being based on human gene sources, that way if a non primate animal is given gene therapy that quadruples its lifespan, it is shown to be harmless to primates thus harmless as well as possibly beneficial to humans repurposing it
Green lines on highways instead of yellow are better
Progesterone like contraceptives could be more beneficial for girls from at or before their first period to when they are 18 to have minimal effects on height, bone development and to promote clear skin, new progesterone like contraceptives could be developed
A micro mechanical version of a cotton swab a person can harmlessly put in their ears, it could be even more pleasurable than a cotton swab, it might have microvibrating motion while being soft and also removing earwax, they could call it an R-tip
° Eric the circle looks even more circular with vector graphics
(Illuminated manuscript ° in color) Eric the circle goes to a renaissance faire
Find out if there are people who are absent a 13% reduction each decade in dopamine neurons after 40, do psychometrics on their personalities and find the 99th percentile of subjective well being (happiness) and find out if they have more youthful personalities, also do this with neurotransmitter neurons of any kind that decrease 7% or more per decade, these could be beneficial genetics of young personality and also have longevity benefits
perhaps I will think of an Eric the circle cartoon
h°llywood Eric lives like the rich and famous
If concrete can be prestressed perhaps metal can be prestressed, that could give springs and waffle springs longer life as well as different characteristics
Also laser soft spots, they could make one spring then use a laser to soften-anneal areas of the spring to customize its load response curve or increase life from reduced brittleness, a waffle spring might have more give and last longer, the laser could make a bunch of warming dots on the surface of the spring
Pressure relief gaskets might already be laser treated to give linear response regardless of how far the gasket material is from the perimeter, I read vehicle airbag covers that look like vehicle interiors are microperforated with lasers to make them disassemble harmlessly if the airbag inflates
(°) ( )
( ) Eric the circle has a pop with a veggieburger
° crop circle Eric
(Image of phone with a circle on it and the word Geometr on it) Eric swipes right!
Telomeres have just a few amino acids repeated, could enteric coated versions of that sequence, linked to a membrane transport and nuclear membrane transport molecule, with an enzymatically degradable linker lengthen telomeres, noting endoplasmic reticulum and individual amino acids I can't see why this would work, but if it does it would be a longevity technology, if it does work then using enzyme resistant D amino acids to make the telomeres supplement could cause greater telomeres durability
Things that fill children with happiness
Candy that sticks to the sides of your mouth, xylitol sucralose caramel but with children's most popular flavors is absent cavities
Affection from parents, what is best style for each MBTI type or big 5 cluster children
Unlikely, but that thing where people wave their fingers in front of their eyes could be used prophylactically even at the mentally well and happy, this could benefit already well children
Can you glue on refractive index matched facets to a gem to make it bigger and glitterier
Polyethylene terapthalate containers
I read there is a charity that urges people at the developing world to put water in .5 liter containers and leave it out in the sun where warmth sterilizes it, possibly with a UV component, they could make the educational effort include optically transparent but IR absorbing plastic additives so the water is ready much sooner, also if the UV component has an effect then containers with slightly different curves with UV lensing plastics could could make micro points of 11-100 times greater UV at interior convection areas of the water, the ones I saw an image of were a few feet off the ground on reflective posts, developing a flatter flask of higher volume with so much heightened efficiency from transparent ir absorber and UV lensing that it still sterilizes water even when just tossed on sunny ground, and sterilizes more quickly would be beneficial, it might be even more fiscally effective to make an adhesive polymer sticker that a person could put on any .5, liter, or, if possible 2 liter container to make that container generate drinkable water even if just tossed haphazardly on the ground. If such a sticker is 1-2¢ then a billion containers is $10-20 million
Siliconized balloons that are extra slippery
There is a drug that causes heightened orgasm and greater sexual interest called Foxy it might also be called 5-MEO or 5-methoxy tryptophan it is beneficial to screen a library of molecular variants to find versions that heighten orgasm even more and increase sexual avidity even more, putting a halogen or ethynyl group or phenoxy group may do this, finding a version that increases sex drive the most even when it wears off is beneficial, giving the drug to teens and children, optimally increasing their sex drive throughout their lives is beneficial, the brain, spinal cord and possibly peripheral nervous system areas that respond to Foxy could be genetically enhanced to spontaneously produce the same amount of pleasure, sexual avidity, and greater sex drive as being dosed with Foxy
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Verify ecstasy effect from solitude effect technology is published, causing absence of human interaction, make it so all grasses and tree leaves are edible, warm food or fire as well as fire visuals causes 72 hour dreamless narcolepsy while making people eternally youthful with death optional, make it so two or more people near each other continuously are dreamlessly asleep the entire time they are within 300 meters of each other, as well as being impervious to weather, particular groups of neurons may activate together or in sequence when a human perceives another human or any kind of companion, activation of that then causes narcolepsy, any organism that bites a human is instantly sterilized and is made unconscious and nonmoving for 96 hours, dermis, connective tissue, possibly a prion absent effect on humans
Kernal type addressable corn, that is maize could make a pixel level programmable image or also text representation of a high utility image like how to make a well, scion and root a nutritionally complete fruit tree, teach reading, the genetically engineered grasses bred to make microcorn ears could store thousands or more useful images, millions or billions at fields rebreeding, that is hybridizing the corn could make it so that if the image had a corn tube perimeter line of all one color or transparency then the image or text was the same as the content the corn was programmed to communicate, this way 21st century humans could use genetic engineering to program graphical descriptions of the million most beneficial and useful things to know into microear corn like grasses, dominant and recessive gene technology would, when the dominant genes were there, breed stays valid identical copies from a single kernal, a plurality of recessive genes with a normal distribution peak would combine,often,to make a viewable understandable copy, and further hybridization of the recessive material when it made a full perimeter line would be a high quality image
20-40 flash drive backups
Gig woow toot kook gog
I read that some drugs increase production of skin oils, could those be an oral dermatitis therapy, some might be sex hormones, do any variants of 17 alpha estradiol which is published as causing greater longevity produce beneficial only greater oil output, other chemicals like DHEA might do this
I favor people retaining all of their adult teeth, but during the 20th century some people had dentures, perhaps it is possible to make dentures completely comfortable if cofocalized lasers are used to desensitize or even ablate nerves under the gum line
Salicylic acid makes yeast live 400% longer, it looks like a benzene with a COOH and an OH on it, they could test all three alternate positions of the COOH and find out if any cause c elegans and yeast and mice to live even longer, possibly develop able into a human longevity drug, also they could find out where at the yeast cyte the salicylic acid causes the greater longevity, is it a surface receptor, something in the cytoplasm, or a nucleus thing, attaching a poly D amino acid to the salicylate might keep it out of the cyte but still be active at the surface, attaching the salicylic acid to a nuclear membrane transport peptide might concentrate it at the nucleus (isotope studies) and a membrane transport moiety might concentrate it at the cytoplasm, any of these might heighten the dose efficiency and benefit drug development for mice and humans
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Maddie mentioned wanting to be a child psychiatrist
Print out things at library for Maddie
You might rescue even more people as a drug developer, the Drug development multiplier 20-40 researchers on wellbutrin 100-200 million person years of wellness, 10 million person years of wellness per researcher, internships might be possible
Sat practice can raise scores 100 points, suggest practice MCAT anytime even as freshperson
Western tuition exchange, college internship offices
Get a medical patent to increase medical school admissions likeliness, see if you can license it
Family play dolls with accelerometers and positional locators could be combined with software to numerically diagnose, that is numerically link play style to the illnesses most responsive to medication
Consider the developing world, 1/10 of a cent dosing, and how iron supplements while pregnant prevent schizophrenia, what other supplements might be beneficial
Intern with doctors without borders
Amazon.com is likely to have a book called how to get into medical school
Mention rapamycin, it makes mice live 60% longer and is a nootropic, I am on it
Write on December 3rd
What majors have the highest medical school admissions success
Ask if taking college classes early was fun and a good idea
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