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Blackborow, M. & Packulak, C.
WELCOME TO OUR PRESENTATION
Did you know? By the late 20th century, Randomized Control Trials (RCTs) were recognized as the guideline used for therapeutics within medicine. In 2004, there were more than 150,000 RCTs published in the Cochrane Library (Randomized controlled trial, 2022).
Did you know? By the late 20th century, Randomized Control Trials (RCTs) were recognized as the guideline used for therapeutics within medicine. In 2004, there were more than 150,000 RCTs published in the Cochrane Library (Randomized controlled trial, 2022).
The RCT is often considered the 'gold standard' of clinical trials and the best way to generate evidence of a causal relationship (Anand, R., 2020, p. 1). The predominance of randomized controlled trials is being challenged by researchers who champion qualitative research methods as methods of gathering more robust and well-rounded evidence.
Early Examples of Blinding
Early Examples of Blinding
In Paris in 1784, a study was performed by the French Royal Commission on Animal Magnetism to evaluate a mystical force known as Mesmerism. Mesmerizers claimed the ability to heal patients by touch or even by contact with an object that was 'mesmerized'. An experiment was performed, and the sample was split into two groups, neither group aware if they were in contact with the mesmerized object or the placebo. When blinded, mesmerism lost its power but the effects of blinding were well proven (Anand, 2020).
Early Examples of RCT
Early Examples of RCT
The first published RCT was performed in the United Kingdom in 1948 by the Medicine Research Council testing the efficacy of Streptomycin in the treatment of Tuberculosis. One of the authors of this paper, Austin Bradford Hill, is credited with pioneering the modern RCT.
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