Other Awards and Significant Particulars of Isidro  A.T.  Savillo

ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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Note: Old Google Sites are no longer accessible or viewable. Therefore your search results will be an error 404 supposedly, effective September, 2021 but in my pages, it started earlier. Follow directions for my new Google sites. Sorry for the inconvenience.

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GO DIRECTLY TO THE  NEW UPDATED PAGE ; Page  3 ; Page  4 ; Page 5 ; Page 6 ; Page 7 ; Page 8 ; Page 9; Page 10; Page 11;Page 12.

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Primary Articles to Read on COVID 19

So you want to get infected by and spread the coronavirus SARS COV2?  then Do THIS. After reading, Below this article is a link titled: Things You Should Never Do During The Coronavirus Pandemic.  Click on the Link and read.

What happens to your BRAIN?

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Updates are below this page. Please visit!

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Introduction-

For the Subpages Section, they are located to the left of this page.

 Some substantial links /information-

Pyxine cocoes, Discovery, Bioindicator/Biomonitor, Atmospheric Pollution

Common Questions:  (For updated search  results  involving Google Sites Pages, please scroll on  pages located in extreme left to find it)

 Discover, I.A.T. Savillo  Discoverer

ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

Impermanence of Sexual Phenotypes

Common Questions: (For updated search  results  involving Google Sites Pages, please scroll on  pages located in extreme left to find it)

Discoveries/Discovered, I.A.T. Savillo  D E 

Scientific InfluenceS, E. Meyerowitz  (Impermanence of Sexual Phenotypes, On Plants), the OtheR is H. J. Sipman (Extensive global studies on Lichens) anD, S. Stephenson (Global work on Eumycetozoans).

Common Questions: (For updated search  results  involving Google Sites Pages, please scroll on pages located in extreme left to find it)

Outstanding International Researcher (OIR); I.A.T. Savillo, OIR

Research Participation

Award(s)* 

Common Questions: (For updated search  results  involving Google Sites Pages, please scroll on pages located in extreme left to find it)

*Award Highlights-   ** ;   ** ;   ** 

*Please scroll below to see the plaques/certificates of some awards. 

Professions

Isidro A. T. Savillo Institutions (Pls. see recent news [bottom part] regarding UCLA and Covid 19 update in the New Page.)

*For the rest of the awards and recognitions, please scroll down this page and also visit the new page [to find them]  and go to: peoplepill.com/people/isidro-a-t-savillo in the Other Interests and Awards Section. Thanks.

Literary influenceS, Joe Bratcher anD, Erica Byrne. I have A's (excellent performance) for both.

Common Questions: (For updated search  results  involving Google Sites Pages, please scroll on pages located in extreme left to find it)

Isidro Savillo's Book

Novel Yelwa Yauri

Ongoing Novel/Script: Amidst Old Los Angeles (Please Search Online)

@Reasonator for I.A.T. Savillo

The Library of Congress Copyright number for the novel, Yelwa- Yauri.

Planning to Organize the "International Festival for Very Short Films" (IFVSF) 2021Copyright, Registered

[Please see FB/FamousFix Pages for the announcement]

Organizational Development InfluenceS, Society of Wetland Scientists, Org, U.S.A.

Society of Wetland Scientists Asia Chapter and Society of Wetland Scientists South American Chapter (Pls. see New Page for details)

Current  Bio  (cached copies of the article and all its accessories; history, talk are available online- search and save) [Pls visit Subpage Isidro A. T. Savillo Archive 3]

Google Latest News: Isidro A. T. Savillo

Google Arts and Culture : Isidro A. T. Savillo

Google Arts and Culture : Yelwa Yauri  

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Memoirs- Wetlands

My experiences as an Organizer and the first Regional President of the Society of Wetland Scientists Asia Chapter has broadened my mind-

I am grateful for all the assistance that the Society of Wetland Scientists Org USA has extended by attending board meetings and presenting papers in their international conventions. Hotels are great and all the great experiences I will always remember. To mention a few- the Sacramento, California meeting, Washington D.C.; Madison, Wisconsin; Salt Lake City, Utah; the Cairns, Australia; the Prague, Czech and the Taiwan meetings  as well I also thank America's Wetland for my attendance to the World Delta's Dialogue Conference in New Orleans, Louisiana.

Am grateful to see my keynote speeches and papers in theses of students in Taiwan (see subpage), being mentioned in an ecological summary of papers at Kyoto University and having great wetland scientists friends (members of the SWS Asia Chapter) as far as Nepal, India, Japan, South Korea, Taiwan, Pakistan, Bhutan, Vietnam, Russia, China (when there was no Chapter for PROC at that time),Turkey, Bangladesh and all the rest of Asia. Having organized the South American Chapter of the SWS, I also was able to develop friendship from all countries comprising South America. You will always be remembered. I also thank AusAID for sponsoring my trip to Cairns. A big thank you to all Presidents and officers current and past of Society of Wetland Scientists Org USA and all organizations mentioned. ~~

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*As a Hallmark

I remembered a chubby male student/participant in the Taiwan Meeting who came to see me and said plaudits about me-- first time I had a Taiwanese fan! I was a bit mesmerized.

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Just to say from me-

All Wetland Conferences mentioned above are First Class and very well organized.

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 Remembering the L- Shaped house where the fictitious love  story mostly took place at Yelwa- Yauri. It's nice if this could be immortalized* and be a place for visits. It's a landmark bounded by the Niger River and the spans of  lands, abodes, church, etc. and sparked by the natives with their daily routine. 

-The novel, the script, and in the future the movie. 

*Immortalizing a place is similar to the true story that is with the Out Of Africa  but with Yelwa Yauri, this is a fictitious one  but the place/house is real and could be a special landmark to visit and recall the dramatic love story that had existed upon it.  

 Author of  Yelwa-Yauri.    Author of Out of Africa 

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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Pls. see Isidro A.T. Savillo's biography online for this award. 

Other Awards-

International Achievement Award in Wetlands by the Taiwan Wetland Society

Green Biorights Award for Sustainable Development by the South Asian Forum for Environment (SAFE) of India

12/05/2012~ Award of Excellence bestowed by the Centre For Clinical Diagnostic Oral Sciences,  Barts and The London, Queen Mary's School of Medicine and Dentistry, U.K. through their Molecule  of the Year 2010 scientist- recipient: Dr. Muy-Teck Teh.

Society of Wetland Scientists (SWS.Org) President's Service Award-

Memoir

Though I received a certificate of NSF (National Science Foundation) Participation in research at CSUDH (California), I consider this as my first major award from the United States of America. This is metallic solid+ glazed green in the mid  - outlined by mirror like metallic edge (not shown in photo because it reflects the light when shot)  and it's heavy and it could be hanged. Letters etched in gold. Manufactured from Colorado- All Sports Trophies Inc. This is the President's Service Award bestowed upon me by the Society of Wetland Scientists, Org, USA.

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Speeches-

Savillo, Isidro T. 2011. Saving the Wetlands: A Synthesis*

and  Savillo, Isidro T.  2011. The Roles of the Mangrove Ecosystem in Ecotourism, Sustainability of Food Sources and Coastal Protection

(the abovementioned two speeches by Isidro Antonio T. Savillo are copyright registered- anybody modifying or using these submitted PDFs or in PPT forms without his permission is extremely prohibited) "As usual, it is nice to brush elbows with UN officials, wetland international experts and other stakeholders in an international workshop... well...well... the funded invitation was great...Thank You!" [ Note: this int'l trip was  postponed due to a circumstance beyond one's control]

Current Work- Mangrove Lichens

* Mangroves and Coastal Forests are attenuators of tsunamis--- who said this first?

1. RAP PUBLICATION 2007/1.The role of coastal forests in the mitigation of tsunami impacts. Keith Forbes and Jeremy Broadhead. Food and Agriculture ...

2.  Eric Wolanski, Coastal Wetlands: A Synthesis. In: Gerardo M. E. Perillo, Eric Wolanski, Donald R. Cahoon, Mark M. Brinson, editors, Coastal Wetlands: An Integrated Ecosystem Approach. Elsevier, 2009, p. 1. ISBN: 978-0-444-53103-2ªCopyright 2009 Elsevier B.V.Elsevier

Great Authors! I congratulate all of you for being pillars on this!

 "I was able to personally talk to Dr. Donald Cahoon in Louisiana and the late Dr. Mark Brinson as one of our advisors." by I. Savillo  

3. Savillo, I.T.  2011- statement about the occurrence of tsunamis in Japan in 2011 as the Regional President of the SWS Asia Chapter Org. (originally posted in the SWS.Asia.org.)

4. The rest followed..

-o-o-o-o-o-o-o-o-o-

The status of Epigenetics- There were some releases of abstracts ( I'm not sure if these are already published but well presented)  using algorithmic models (I hope I termed it right), statistical models or probably mathematical models lacing itself through the mechanisms of inheritance. But there are a lot of doubts as to their conclusions. On my part I would rather have molecular markers to tag these probable epigenetic characteristics that were successfully passed on to their progenies. Without the molecular tags, I doubt if these models could work out.

To recall, this is what E.O. Wilson of Harvard University which I keep in my Theoretical Web Page until now wrote/said-

 "The annals of theoretical biology are clogged with mathematical models that either can be safely ignored or, when tested, fail. Possibly no more than 10% have any lasting value. Only those linked solidly to knowledge of real living systems have much chance of being used." 

That is why I am more perceptive how the molecules of epigenetics are being passed from one generation to another by knowing, tagging and molecularly exploiting the "genes" responsible for them and how these are modified, by- passed  or twisted by the environments, both internal and external" to assume the epigenetic phenotype. In fact the Epigenetics of Homosexuality has been "hot" for some time and I still hold firmly to my Theory of the Impermanence of Epigenes.

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 Diseases as Molecularly  Defined~~2016/November

by I. Savillo

The causes of infectious diseases include the pathogenic (opportunistic)  microorganisms, specifically their microbial toxins/enzymes [and the microorganisms as infectious and the  specific microbial proteins (but in special cases some may also be infectious) as toxic].

The causes of infectious diseases that are genetically (or epigenetically) produced are the misfolded proteins* [and likely  misfolded proteins are infectious and toxic].

The causes of non infectious diseases  that could be possibly  passed through generations are the   purely chromosomal and/or extrachromosomal genetic diseases and/or  the epigenes [and their products (proteins), the presence or absence thereof as causes of the diseases].

The causes of non infectious diseases are the "environmental toxins" which may include the allergens among others. This could be due to the lost ability of the genes/genetic products (proteins) to stop or neutralize as well as get rid of these environmental toxins [where in special cases they may further influence/trigger the gene through mutation etc. or  genetic product (protein) to produce a protein that may cause a disease].

Therefore Diseases are caused by 

some special type of proteins

[the presence or absence thereof].

*"misfolded proteins" from the late Dr. Susan Lindquist.. Thanks and RIP.

 Is there anything that I forgot to include among the given statements?

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Epigenetics Theory on WBC/ 2016/Nov.

Way back some years, I remembered reading an introductory paragraph about Microbiology in the Microbiology Department of UCLA. It says most likely that "A cell [it could be a microbe or a human living cell, in my understanding] is an organism by itself." Therefore, the cell has to defend itself as well as post translate itself into something different. [I used “itself” twice just to put emphasis]. There are WBC  where some pathogenic viruses could not come in due to particular mutations most likely in their membrane receptors. In fact the latter are always in mind if cancer is brought out (but not necessarily on WBC). These are as fickle a pseudo or a plastic type of molecule. Nevertheless, as in the case of CCR5 mutation for reasons that some  are HIV positive but may not develop AIDS, this may be a translation product as expressed by the gene most likely in the hematopoeitic stem cells. Then this is purely Genetics. In fact there is even a test to determine if one has this “beneficial” mutation or not. But WBC has a way of reacting towards the pathogen: such feedback as to the quantity of production and type of cells that need to be produced during the onset of infection. Considering that it has this motive, then why not do something about itself in order to protect it from invasions of these viruses through their membrane receptors for one? It could be a post translational scheme of the epigenetic factors (like the histone). Or it could be done during the translational processes. It could be a participatory of an external/neighboring gene and/or a non- genetic factor (in the environment). Or mechanism more than the epigenetic aspect.  It's life span may be short but in such lethal environment the modifiers during the post translation processes could have been alerted to help in its normal existence: a post translational/translational/transcriptional modification or even mutation. If it is a mixture of WBC with and without the mutation, then the modification could have been within the molecular process post replication. It could be outstandingly worthwhile if the stems cells are the ones being mutated and the rest are wild. Live it up WBC!  Still without AIDS, it is claimed that the HIV has some implications in cardiology and oncology (as to a recent news).

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Nov/6/2016`` On Candida auris . This is a microfungus having  yeast and filamentous forms that is considered as multi-resistant against fungicides. If we compare bacterial antibiotics- there are various sites/substances that it targets, like the cell wall and particular points in protein synthesis or a mistaken similar metabolic molecule that unfortunately will not lead to the production of an essential molecule and all of these would lead to bacterial death. Some of these bacterial antibiotics are in modified form or even a product of molecular manipulation. Most of them are directed to specific types of bacteria. But in fungicides, I think it is still in a generalized level of control. It seems that the idea that "any pathogenic microfungus could be killed by any fungicide" is becoming a consideration. Therefore now that there is  a show of resistance then it is high time to explore the other essential targets involving other molecular structures and metabolic pathways and to pinpoint/locate that particular target (e.g. in the  membrane, enzymatic cycle or etc.) wherein an appropriate fungicide could be developed to lyse or destroy this target in the specific microfungus leading to death[of this microfungus].  It would be nice to widely explore the fungicide arena as to its production and/or synthesis similarly or even much more than what is being done with the bactericides. 

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11/6/2016` A species of Dirinaria is the foliose lichen that can survive very well the saltiness of the oceans as a prominent component of the mangroves.  This species was also mentioned in scientific papers on mangrove lichens from India.

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11/8/2016`` What will be ISMCBBPR's Molecule of the Year for 2013?

Here is a photo of the Molecule of the Year  and succeeding Molecules of the Year as an ISMCBBPR award- (Previously, as a Science Award). The voters are kindly being perked up for the upcoming activity!

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Satisfying one's curiosity...11/8/2016

When searched in Google (archive)-  Yelwa-Yauri , as a novel

Yelwa-Yauri is a novel written by Isidro A.T. Savillo, registered at the Library of Congress in 1997 having this copyright number: TXu000784992  and likewise registered at Freebase (identifier:/m/011synkt) as a book written by Isidro A.T. Savillo.  Retitled as Beautiful Tears when it was registered as a Treatment at the Writers Guild of America, West and this novel was submitted to the Opus Magnum Discovery awards in 1997.

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``I just assigned a graduate topic in the Advances of plasmids and cosmids and later to my dismay, that cosmid is being used as a page of immoral value. The next time you do research online for cosmids use  keywords "Advances in cosmids", so you'll be transported to the scientific molecule which is the real cosmid.

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Cellular versus Organismal--

It has been known proteins exhibit plasticity. Way back years we talk about the plasticity of the gene but because of the various processes happening within the protein synthesis level including the post translation-[ I was about to say post protein synthesis but that will make the highly molecularly  manipulated protein exclusive of protein synthesis  and it looks gross- so stick to post translation] of the protein [rather than the gene], the latter I think is much better used in discussions. Therefore, we have proteins that could be as fickle as they are post translated... where post translation could be their last or are there still some more processes before it will build up the real FINAL protein product past post translation [that we use to know at present]? Probably, there will be some revelations of these new mechanisms in the future. Let it be a never ending research. So, it is true that due to the "ficklemindedness" of these proteins it is expected that it could bring phenotypic variations, cellular and/or organismal. How about the "Organism" as a whole who is fed by these kaleidoscopic maze of proteins  and is a sum total of all these biological proteins could think and speak as if  it means to be permanent and the "organisms" who are listening, believes in its permanency later to find out the plasticity of its reality. I think if there is cellular psychology , it is much better than the organismal one. It seems that they are just not parallel at all. Is this an evolutionary  direction? We all live in a flurry of lies an antithesis of what the cells are. Even how true, the truth is, this is overshadowed and camouflaged  by uncertainties and alternatives in a split second.

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11/22/2016~~ 

  ~~Beating Discomfort with Discomfort- 

Re-reading the dissertation of a colleague  from Sweden on "carbonyl reductase in fish", which she sent to me ---  in her introduction, I just can't help thinking how humans  use materials for their own comfort but those materials are unconsciously toxic to humans. It could have unfavorable cellular and at the end an organismal reaction.

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11/23/2016`

Some concerned links-

I.A.T. Savillo in Google Scholar

@Reasonator for I.A.T. Savillo

 The Library of Congress Copyright number for the novel, Yelwa- Yauri.

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For the Wikisource, you may check on its cache and see my Wikisource number and its rulings. Thanks.

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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On Cell from  Cell (Journal) most recent-

A graduate student talked about the crystalline structure of the cytoplasm  in E. coli.  Deducing that this bacterium is "forever" vegetative, it needs this kind of "defense". But I wonder if this is true to all bac including the endospore forming? It needs to narrow to some kind of generalization after  lot of mutilations.

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The genetic code being claimed as universal by some  is  limited in scope. Others have different equivalents per triplet and others have genetic sum as haploid. Whether these are their special characteristics they could be considered as organisms unless they could in visible light transform or re-transform themselves into gametes so such as they are, then they most likely be called as such.

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Tissular-

Using this in scientific papers has given new insights that cells maybe similar or different within a tissue could have their own biochemical bearing for an important exclusive phenotype. Well cellular we know it refers to cells while organismal as defined ? does not refer to an organ but to the organism as a whole- then tissular is maybe necessary in this respect- for  more meticulous explanations of what is broadly or narrowly happening within the organ. ..terms...terms...terms.

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Waiting Game

The Deuteromycetes and the Myxomycetes/Eumycetozoans

These are the microorganisms that could not fully experience their full metamorphoses unless one dig them up and expose them  to an ambient environment to germinate or put an appropriate chemical/nutrient medium on them in the laboratory. Without anthropogenic assistance, they wait for nature to do it.  Imagine the deuteromycetes meshed or buried in a compost pit or eumycetozoans in an almost watery environment... Can they develop and "flex their legs" and raise their fruiting bodies up in all splendor? (legs are stalks).  Only if the environment says so.

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*Whenever a post is made the date is recorded in the revision history of the google page. So no need of putting dates.

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Antivirulence agents versus Antibiotics

Antibiotics kill but do not spare the pathogenic bacteria in releasing toxic substances once the infection takes place. Therefore, the virulent factors are the target of the antivirulence agents. I can see a similarity with the drugs used in HIV but when it is presented the immune system could not kill the bug which is otherwise in bacteria. Antivirulence agent is also considered as a bacteriostatic type of antibiotic - it needs the immune system to complete the work. But I think antibiotic is still needed here or will be dosed at the same time as long as they are not in conflict because the effectivity and efficiency of the Antivirulence agents must be as great as that of the antibiotics to prove its success. Also it must not be toxic to human cells.

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Wetlands

My experiences as an Organizer and the first Regional President of the Society of Wetland Scientists Asia Chapter has broadened my mind-

I am grateful for all the assistance that the SWS Org USA has extended by attending board meetings and presenting papers in their international conventions. Hotels are great and all the great experiences I will always remember. To mention a few- the Sacramento, California meeting, Washington D.C.; Madison, Wisconsin; Salt Lake City, Utah; the Cairns, Australia; the Prague, Czech and the Taiwan meetings as well I also thank America's Wetland for my attendance to the World Delta's Dialogue Conference in New Orleans, Louisiana.

Am grateful to see my keynote speeches and papers in theses of students in Taiwan, being mentioned in an ecological summary of papers at Kyoto University and having great wetland scientists friends as far as Nepal, India, Japan, South Korea, Taiwan, Pakistan and all the rest of Asia. Having organized the South American Chapter of the SWS, I also was able to develop friendship from all countries comprising South America. You will always be remembered. I also thank AusAID for sponsoring my trip to Cairns. A big thank you to all Presidents and officers current and past of Society of Wetland Scientists Org USA and all organizations mentioned. ~~

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*As a Hallmark

I remembered a chubby male student/participant in the Taiwan Meeting who came to see me and said plaudits about me-- first time I had a Taiwanese fan! I was a bit mesmerized.

__________________________________

Just to say from me-

All Wetland Conferences mentioned above are First Class and very well organized.

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*Updated (see New Page on CSUDH) 

Long Beach Harbor California

I remembered getting samples of Octopus bimaculoides at a USC  research Centre for our research in vision at CSU with E.M. (now A Director/Hospitalist/Internal Medicine Specialist at a University of Miami Hospital) my senior partner in research. Nice place...

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 First Molecular Books

My first Molecular Book I received it  from Cold Spring Harbor Lab. written by Drs.  Joseph Sambrook, E. F. Fritsch and Tom Maniatis with the title- Molecular Cloning: A Laboratory Manual- 1989; 1st edition.

In addition I also received two volumes/books of  advances in molecular biochemistry from a Filipino M.D., Ph.D. who once worked at Harvard  University. I am trying to remember his name. He is by the way Dr. Samuel Bernal.

Second Molecular Books

From Caltech Bookstore- Molecular Biology of the Gene; Molecular Biology of the Cell (by Alberts)

Third  set of Molecular Books-

Molecular Protocols (A Series)

I also have to thank the Mary Ann Liebert, Inc. for  the Genetic Engineering News that I had been receiving  a hard copy each month from the U.S.A. and to the hardworking person who facilitated sending them to me.

*For those who want to follow a path of a Molecular Biologist, you may start  reading/buying  the above mentioned references..

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Internationally noted Ichthyologists

~Currently communicating with these scientists on fishes and am glad for the quick response-- no names mention first- from Hawaii, then I'll communicate soon  with a species expert in Japan... Thanks

Done but I may soon need their help somewhere.

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THE ISTE or the Int'l Society for Taxonomic Exploration  has a new sub page with the title of "Marching blue crabs*". Search online please if interested.

*Most likely first reported from Iloilo, Philippines or Panay Island, Philippines. Mictyris brevidactylus Stimpson, 1885 has been reported in Mactan, Bantayan, Camotes, Bohol, Palawan by G. T. Poppe and P. Poppe.**

**No cache/actual photos of having light blue carapace and scarlet banded jointed walking legs. 

Has been reported by Estampador (1959) in Bantayan, Cebu Province, Bararian, Sulu,  Palawan, Iwahig  but this was recorded under  M. longicarpus as a var??? 

-Thanks for the confirmation of identification from an expert  crustacean scientist in Singapore. According to this world expert in crustaceans, he was able to see these species in Panglao, Bohol many years ago.

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New Knowledge 

Submerged Portions of Mangroves as a "Macro- Sea Grass" with its epiphytic components

  by  Isidro A. T. Savillo

  In my observation, during low tides, I have seen species of mollusks on the leaves, stems , trunks of mangrove trees and also particular microscopic algae in niches of their branches. As observed, they may feed on these micro- algae. These are just pioneering finds (as to what type of micro- algae are there) and I believe there is still more that submerged components of mangroves can be ecological shelter of epiphytes ( as to what species besides the micro- algae) and would be contributory to a new type of an ecosystem.

Arboreal Mollusc behavior (Previous studies)

a)  Littoraria evades high tides.

*In my observation, there are gastropods that are still up the branches and leaves of mangrove even this mangrove tree is in a dry stand.   -Previous study stated that The delaying mechanism of migrating upwards is due to feeding. Is it? When they can spend all of their time up the mangrove tree if they wish to skip the epifaunal habit of feeding. And migrate downwards on the trunks that have been exposed to high tide level and be scavengers (as previously claimed) to whatever the sea/brackish water has brought but not necessarily go down to the muddy area. The "timed"mechanisms of migrating downwards and upwards have to be totally analyzed because they are slow enough to evade high tides. Another study- UNU report on mangroves stated that a species of arboreal mangrove mollusk (missed its genus) is resting. 

*If the Littoraria are good sensors or any gastropods, then they could be used as prediction guides for high tides or even tidal waves or even tsunamis!  (Tsunamis take time to develop?? and are not part of the usual rise-and -fall of waves).

In previous lit, there is a Littoraria species that favors high tops and they have thin shells and they may not favor going downwards to escape the crab predators (because of their thin shells). Probably this could be the target organism. And probably they favor more the dry environment. "The higher they migrate upwards the bigger the waves." I am just posting this for there are various lit on this organism then why not try this?

b) Littoraria has been reported to eat microscopic algae, microfungi, algal filaments and mangrove tissues. 

*I hope this is done by actual observation. If this is a laboratory simulation or a gut content analysis, there is a possibility that the source of the substrate was not aerial but could be mud etc. If the substrate has been subjected to isotope attachment and was done in laboratory, then the organism has to be "forced to eat" thus it is not the natural way of feeding. This also shows that the organism is euryphagous. This would then record the eating habits of this organism as something not exclusive of being arboreal-- meaning the staple food could not be pin pointed.

*It is also possible that the arboreal forms could favorably mate given the above the tree situation. Previous study state that mucus trailing of the female? has a pheromones.

"As a Sea Grass"-  Sea grasses could not allow a moveable epiphyte to avoid high tide by climbing to its tip for they are totally submerged. By just looking at the vice versa- where a moveable epiphyte from a sea grass would detach itself from the sea grass once it is high tide for it needs to live in an aquatic state thus make use of the "water laden soil" or become in faunal in the process. 

continuation.. arboreal ecosystem in mangroves

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World of Beautification

As I rode and observed the environmental surroundings, I have noticed the flowers of shrubs and trees, the extra curls of hairs at the back of the ram, the polished look of dogs  etc.... These are the beautification mechanism for sexual display and wants. Others are hidden in thoughts and muses. A stressful everyday load and  this represents I think about 30- 50 % of an organisms' pre-occupation in every second of its life. It is permanent and difficult to efface but can be toned down. Yet, it could still find a "leak" and be expressed. I don't think that these sexual signs come only during adolescent or puberty in humans or adult stages in lower animals. Throughout the development of the organisms from zygote to senility these beautification processes and displays are occurring by means of cellular and molecular mechanisms undetected and these could ripen or found visible in latter stages but sometimes even earlier. A cell, a tissue , an organ have to waste these energy in everyday life for not any of which opt to remain neutral or non functional when it comes to sex. 

ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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Rau versus FAO-

On Marbach

I can say (Rau vs FAO), they compliment each other somehow... But I have to say FAO's new scheme of identifying fishes excites me  just like what Marbach did with the Buellias.

It's just a matter of delicate extreme dissections and inspections (in fishes) or cuttings and microscopic works (in lichens) (the apothecium in delicate slices)! Congratulations!

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==Pre- Valentine's Find- (Deep Sea Fishes)==

How I squint my forehead looking at these 2 species-- the black of the black of the black fishes- Epigonus and Promethichthys ... (using FAO books for i.d. from Iloilo Seas.. somewhere near San Joaquin's town)  by  I. A. T. Savillo 

**These two families donot have specific diagnostic features wherein some facts supporting them need to be broadened or corrected. Probably the reason here is that they are deep sea fishes and may incur more variations than specificities. Some Epigonus spp. donot have opercular spine and a Promethicthys was reported to have a single pelvic spine but in the specimen I looked into there are 2. I will be looking more closely into the two species that I have. They may be a strain or different species. 

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Sometime in 2016- FAO book

I remembered an analysis of a sole fish which has a species of sorsogonensis... Could it be the deficient- in- information  Brachirus sorsogenensis. It was found in Cebu.

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Ecological Terms that need to be dug deeper (Part of Graduate Students Discussion)

1. rheotaxis versus counter current flow

*rheotaxis has been defined in Odum's book but there is also a cellular phenomenon that I consider as part of Physiological Ecology- here the sperm go against the current produced by an oviduct fluid- but I think the sperm has to push through this current so as to reach an egg whereas countercurrent flow may not push through the current but would I think remain stationary passively and actively(? by chance branchial pumping may occur). In the recent paper, sperm's rheotaxis was found out to be passive.

2. pheromones versus chemical cues

*pheromones have greater applications in ecology than chemical cues. It is usually associated with chemicals produced in the human body (e.g. male smell repels by female thus leads to female- female attraction because female smell is not repulsive to the female partner, etc.) or during the about-to-spawn behavior of female fishes or when some mammals are on heat. While chemical cues are useful for tracking spawning places which were formerly the areas where the trackers were hatched and most importantly, the specificity of fertilization...e.g. when gametes of different coral organisms burst at one moonlight in November (?)  at  GBR, Cairns and each species gamete has the specific chemical cue to locate the species opposite gamete for fertilization. Thus, chemical cues lead to specificity.

***I really don't know when and how (again) these terminologies be further applied and extended.

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On Standards-

When I came into my senses, I was asking questions of the standard way of raising kids? Until now there is none. Currently what jumps to my thoughts is the standard for raising(/sustaining) geriatric.  Is there one? I don't think there is one. Both standards supposedly would result to the very best output as expected. The various genes and the various environmental factors that intertwine plus the age make it  difficult to program such standards. 

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Why are the swim bladders used as a basis for specific id for Sillaginidae by FAO? The answer is they are huge- and have particular characteristics by species.  I think they are more gigantic than any of the internal organs. (We have seen the sihama species and I think this is true for all) How nice to dream of how they float! Thumbs up! But our sb has some designs (streaks) not mentioned in the book.

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 My congratulations to Dr. Harrie Sipman, my mentor for the numbers of Libri Amicorum he received from the scientific world of lichenenologists. Congrats!

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Strains of Clitoria ternatea

Wikipedia has an article and accompanying photo of the original specimen. But there are strains such as "doubled flower" and etc of this species wherein in the Philippines, this strain is also observed to be modified. Please visit Clitoria ternatea page. Thanks.

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Qoutable Qoute added to my Qoutes

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On Molecular  Techniques-

One of  my scientific experiences in Molecular Pathology at USC School of Medicine (at Hoffman's) and at LAC-USC County (at Mol. Path Lab. ) is summed up here. Thanks to my Ph.D., M.D. tenured Prof. of USC.

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A Comparative Molecular- Cellular- Environmental Analyses of Segmental Behavior in Autism

  A comparative analyses of segmental behavior between [or among] autistic individuals and with those who manifest such segmental behavior* and are about to  get into the realm of normalcy (though not 100% or even 90%) or even with normal people who manifest these segmental behavior and how they manage to overcome it. The focus will be the organs (specific part of brain, muscles etc., the neuronal pathway involved etc.) , the specific cells and their cellular composition including various substances and the interacting biomolecules and the pathways modified or created otherwise known as the controlling factors. In vitro analyses of the placenta such as placental fluids or fluid where it has substantial presence in the baby considering that pesticides etc. had been mentioned as one cause.  In the context of allergy such as aerial pollution, in adults there are situations of drowsiness or even fainting or dreaming much more in the placenta with the baby subjected for both aerial and liquid  "pollutions". Most likely a new pattern of behavior will be enacted. History of epigenetic origin will also be included in the environmental analysis. Molecular Genetic analysis will also be undertaken.

*Segmental behavior refers to a piece by piece mechanisms of behavior possesed by the autistic individual that would serve as the platform for comparative anaysis.

~Balbc  mice or any murine that  have more or less these manifestations. I know its difficult by finding a mouse that could not bear looking at the other mouse directly to its eyes but scientists know what do . 

*Autistic individuals are deep thinkers one towards the inferiority state, and the other towards the superiority state. 

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Leaf is a Plant : Plant is a Leaf theory of mine came out as a review of an article in Popular Science--- My theory which is this was written in my page and was made into a review---  Here it is:  Review Popular Science Article- Thanks for the 4 rating.

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Mystery behind this Aerial- Runner Plant from ISTE.

Updated..

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My research  study at CSU has led to the detection of the Retinol- Binding Like Protein in Octopus bimaculoides.  I missed the presentation  of our research group at ARVO in Florida, U.S.A. Thanks for the concern. I remembered you called.

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12/24/2008~~ Statement I made on this date about "Instinct" from my Theoretical Biology Page

"....... in standing up for the ist time as observed in complex lower form of animals, etc. It's a cascade mechanism of signals  initiated by birth- just like the bloating of the lungs once the fetus is out of her mom's  placenta that will initiate lung- breathing reflexes. The biophysical influence of the environment here is working.  ....the muti- interactions of organ systems such as the circulatory system, the extension mechanisms of the limbs and the bodies ripe need* for oxygen will drive the animal to stand...and the smell of milk will lead to his sucking needs or her mom's intimate* "signals".  Well human babies are the lowest graded when it comes to environmentally influenced reactions independent of parents compared to complex lower forms of animals. Human babies are slaves to ..... their caretakers until they grow to be what they are as influenced in toto (by the enviroment and their genes). They just can't do things on their own. ............................"

Solution: (prevent Autism etc.)

Therefore, Guide/Entertain...etc..  well your babies upon birth so it could become as "normal" as you wish it to be... [remember the learning process of human babies is long...]

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I have to congratulate always the President of IAMURE for inculcating the need for a member of the academe/professors to publish a paper  in the journal indexed by Thomson Reuters - the present day equivalent of ISI. In the international arena as a speaker professor your publication is being sought to otherwise........................! If it is not of Thomson Reuters better what keep quiet?? or step down the podium??

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As a requirement for my graduate students as well as higher undergraduate students when they do research study analysis it must come from a journal indexed by Thomson Reuters and it must be at least 2 years old or the most recent the better.

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 HeLa cell line

Anyone doing cell culture in a pathology lab. or reading an advanced basic book in molecular and cell biology, for sure is familiar with He La Cells.

Now it becomes a major player in print as well as later in a movie. The Utilizable He La.

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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The Portfolio of the 2008 Society of Wetland Scientists Asia Chapter Convention that includes the proceedings and the publications already has an ISBN.    Another ISBN info. Pls. proceed to no. 28. 

You can look for the proceedings in the Wikipedia article of mine. But here are some of the highlights of the convention.

Each minute of this convention in Taiwan is highly significant.

Preface

Taipei Declaration on Asian Wetlands

International Experience

Agenda

Proceedings and Events

News Report

Publication

Appendix

ISBN of the Portfolio

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I also have to greet and thank  my wetland colleague from the Chinese Academy of the Sciences and the scientific itinerary that you had prepared for me. It was a nice one though! I had seen you frequently attending the SWS Org Int'l Conventions and Annual Meetings.

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Cited in a Thesis four times pertaining to Pollution Tolerant Lichens in Bogor-

I remembered there was this Indonesian student who communicated with me regarding P. cocoes and I think this is  her  and this is  her thesis in Indonesian language. The reference she cited about me can also be found in Biologybrowser.

Congratulations !!!

*Sorry but I am not sure whether it's a he or she... names...names...names

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How important is the copyright!  Avoid claiming it's yours-- even talking about it or displaying ... Here is an archive photo of a wikisource implying copyright strictness-

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Cited in the 2017 paper of the world's expert in eumycetozoans, Dr. Steven Stephenson-

"The occurrence of myxomycetes on mangroves has been studied in Brazil

(Trierveiler-Pereira et al. 2008, Cavalcanti et al. 2014, Agra et al. 2015), Puerto Rico

(Nieves-Riviera & Stephenson 2004) and the Philippines (Savillo 2015)." 

Thanks!

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I haven't attended conferences on myxomycetes lately and here is one important knowledge..

"The role of the myxomycetes within the ecosystem is that of decomposers. Stephenson said that the organisms are very important when considering nutrient recycling. When a plant dies, the myxomycetes break down the dead plant matter, which in turn enriches the nutrients in the soil providing the necessities for new plant life."

Cox, Nicolai. 2015.Steve Stephenson: A Pioneer in Mycology. The Arkansas Traveler.

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Instead of Thomson reuters indexed journal, this is now known as the Clarivate analytics indexed journal which is the equivalent of ISI.

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I'll take look at this later..Quite interesting- Global Fishing Watch

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This is interesting and I haven't encountered this yet in Africa or the bright orange ones among the tall grasses a subspecies or a species.. but the map of distribution does not cover it.. ...Queleas. Thanks Wikipedia.    

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This page also serve as an archive. 

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Google's About Page offers an exciting section- 

What the world is searching for now

-Like it!!

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~Integrative Taxonomy on the way... (Be discussing soon)

There is one recent publication that has done a study in employing both the molecular (bar coding techniques- mitochondrial assay...) with the morphological/morphometric/ meristic biology (no genes though for the latter three as what I proposed last time - See Philippine Myxomycetes web page) to say that it is Integrative taxonomy. 

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My gratitude for the reprint sent by the senior author (?) as I requested it through her and by the "most" senior author Steven.  The "problems" of myxomycetes or eumycetozoans especially those I posted in "Phil. Myxomycetes page"  have been answered.  If you want a reprint you need to buy one from the publisher.

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Weather right now in the Visayas region of the Phil  is not a promising all day bright and sunny in spite that we do have morning sunshines but in all most all afternoon chances are I think that rain will come. Any scientific explanation? In western africa, this happens but only during the rainy season not as frequent as what is happening here and it's not a striking sunshine (as what is happening here in the mornings) but a more or less uniform all throughout a rainy day (in Africa).  All I can say is... the weather phenomenon is always EXTENDED and sometimes some sorts of  "extremes" are being approached.

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Traveling and going places and meeting people... it's like walking in a well paved road saying hi to people of similar interests,  clasping hands and sometimes spending moments with them and at the end of that world wide "walk" , one has to sit down and just find a surprising flow of all the international citations of what one has done.  I definitely enjoy the walk. 

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Some walks are still continuing and all I need is the time for it. I just have to warmly greet the ISMCBBPR Advisory Board and the Voters for the Molecule of the Year. So, too with the ISCSPM. 

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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 It is exciting to know if here in Panay Island will the first announcement of new species for the world and newly reported lichens  for the Phil. will come. 

e.g. Nigrovothelium inspersotropicum  (from the Province of Iloilo is the first reported species in the Philippines*) has an affinity to Nigrovothelium tropicum  formerly known as the common tropical species Trypethelium tropicum (Ach.) Müll. Arg.  Change in species name is due to the massive revision of Trypetheliaceae .  

*though this may be a common species  and may be reported later in other locations of the country.

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Looking at the Good Side--

How other people look at you is something that is funny and bland and considering that these are just true from the heart opinions... why feel so bad? Famous people are usually receiving good and bad remarks. But I think looking at the good side has more vibes on it-- on the Developmental Evolution of Google snippets- It started for long years as a writer, then later it became a Philippine writer, then Philippine Microbiologist, Filipino microbiologist and lately, Molecular biologist. Also the Wikipedia page really received something exciting by being judged as a start class (at www.sdwiki.org/wiki/  search for Talk:Isidro A.T. Savillo or  once in the page click on Talk for the "start" assessment of the page) away from stubs and drafts.  You don't have to be in a popular encyclopedia to receive a snippet (for info purposes)! A colleague of mine has one.

Updated snippet mid 2019- 2021

    I. A. T Savillo again is called a Filipino Microbiologist. Back to where it was before.~12/2019 Lacks a Photo~ followed by having  a Photo of my major award in Taiwan, then there's a photo of mine (usual photo) from Other International Awards ... Page and later without my photo (4/01/2020).. still Fil. microbiologist.. (0ct 8, 2020), Fil Microbio. with photo from Other International Awards...(Oct 10, 2020) Fil microbiol with Taiwan's plaque as photo switching with photo at Other International Awards, photo of Taiwan's plaque remains. (Dec. 2020- All the English sites use the Filipino Microbiologist title but all other non English sites use Molecular Biologist title; the photo comes from peoplepil page... it was taken from my photo with a Taiwanese and a Japanese wetland scientists while we were sitting in a table at the Madison Wisconsin Monona Terrace Convention Center; stayed at adjacent Hilton; attended an International Wetland Conference. Photo reverted (Feb. 01, 2021) to Taiwan's Plaque of Honorable Wetland Advisor for approximately 24 hours then to no photo at all. 9/2021- Molecular Biologist for other foreign sites including Filipino site  changed  to Microbiologist. Filipino microbiologist remains in English site. Photos used are those taken from FamousFix. Oct 20, 2021- Title becomes Microbiologist from Fil. microbiologist then on Oct 21, 2021- It becomes Molecular Biologist. No photos. Oct 28, 2021- Back to Microbiologist, as of the latter. 11/16/2021- Title becomes Philippine writer

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 Published Biography* 

*Taken from 2008 SWS Asia Chapter Convention: A Portfolio (pls. see first subpage)

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Further discussions:

Wolbachia is essential for the survival of Wuchereria bancrofti.  (Grad. Stud. Paper Analysis)

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Pneumocystis carinii inspite of having trophozoites is considered fungal- like. 

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Voles that could not swim from an island  has contrasting genetic variability with one species that could swim. (Grad. Stu. Paper analysis)

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From time to time  int'l citations sprout and they are posted as  sub pages left of this page...

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China again? (Int'l Invitations)

I searched online where the venue of this conference is and where I am a member of the Int'l  Scientific Panel and this venue is so exotic as well as exciting. I can't remember that  itinerary for a scientific conference that I was previously invited but it did not push through (with all the sponsored tickets, accommodations, series of talks, etc). It was also  somewhere located in the Northern area.  Nevertheless, Changchun, Jilin is so wonderful with its winter sculptures like this:

Keywords: academic committee, sws, asia, china, savillo 

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Think Tank- I read about the Conventions  on Biodiversities and I just admire how they tinker with the word obligations. I am thinking of making a paper on these... for future submissions!! Keywords: Harmonizing rather than Politicizing...

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On Pyxine cocoes- my discovery of this lichen as a bioindicator/biomonitor has been extensively used in India and being studied in Thailand and recently Indonesia and currently (2017) identified in a published paper from Malaysia. In India, they did transplants on these. Considering that all the peoples of the worlds are affected by air pollution, In tropical Asia or in tropical countries why don't we look specifically of using Pyxine cocoes as a monitor for pollution in the environment where we live. Better ways of analyzing pollutants by doing a simple test like an inexpensive kit to determine  for the presence of these pollutants in Pyxine cocoes tissues, etc.  In here, Pyxine cocoes will just grow freely without the need of electricity or battery to keep it going like commercial sensors. And also to compare both. How efficient these electric sensors are to detect pollution?  With a transplant  Pyxine cocoes and a kit, you know whether the  place where you live is safe enough pollution wise for your health as well as that of your family.

*this is one (Pyxine cocoes as a bioindicator/biomonitor for atmospheric pollution) of my accomplishments where I was judged as the Outstanding International Researcher for 2010 by the Philippine Association of Institutions for Research. Go PAIR!

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#keywords; catharsis, purge and a new look very comfortable  to surf. Ty!

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 Is it possible for a flower to self pollinate without the help of external factors? My answer is no. Even a slight whiff of a wind when a complete flower closes can help drop the pollens to a flower's stigma. Flowers do not have the accessories of planting gametes to target organs. They are usually mutual or exhibit protocooperation but there is one which impairs its "prey" after  or during pollination (of this prey - so no longer mutual). Probably this a unique  ecological relationship;  similarly as the spider that eats its mate after mating  or is there such thing as during mating, only that in this case it impairs a supposed -to- be- friend  a pollinator but also a juicer of its nectars. Venus flytrap has leaves that kill and digest the insects and are not involve in pollination. Flowers are seen at the top away from these types of leaves so pollinating insects are not impaired or killed. So this eco relationship states that "One member of a Pair is benefited and the other is impaired"-- as the Savillo type in case Odum doesnot have one of this. A Painful type of mutualism/protocooperation in flowers. Sensual trap for the vft while sexual trap for this flower. Common sense this is a complete flower otherwise how can this poor lep be able to bring the pollen to the neighboring species if it gets hooked. Or it looses a leg and continuously pollinate a neighboring species, this is just too grim to think about.

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On Cellular moderation-

Let us not put too much baggage in our cells. That  is so much substances that could be a product of what we eat or think or what ever things we do with our biological systems . Moderation will be fine. Our immune system is not  all the time weak.  It is only when it encounters a new foreign microbe or or a new allergen but it is in the process of working things out to neutralize or get rid of this. It may take time. And soon this will be of no great effect compared to the moment when it was previously encountered. And Unless there is cellular moderation. Whether a minimum  viral titer (unless very much new in terms of molecular proteins/genome that no other common microbes share)  or  any substances (as long as not highly toxic or poisonous), etc. this could not  create extreme consequences considering that their cellular moderation status is maintained. To help in this moderation in numbers [or in quantities (e.g. such as substances)],  there is a need to  use medications or probably substances from natural products that are tested to be appropriate for that disease. And think in moderation too. Don't panic.  Once there is cellular moderation, one can be healthy or would move towards a healthy life... for whatever disease or disease to be.

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ISMCBBPR News Updated. 

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To catch a run away toxic  monster....

Cancer cells are products of proto oncogenes that have gone awry. It could  be any of the following: (as a result of genetic mutation) extra copies , hyperactive genetic products or expressions , amplifying transcription activities, gene fusions resulting to a gene with oncogenic properties.. etc. Besides killing those abnormal cells,  catching/ neutralizing/minimizing  those oncogenetic products may work. And to look more closely to the abnormal patterns of protein synthesis and to tweak it somewhere else without affecting the  PS of normal cells. Or a highly dividing pseudo cell that could welcome these op to its membrane receptors where it may re process it to a friendly molecule once it is internalize and/or the said cell will undergo apoptosis no longer be able to reincarnate the op.

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Was not the usual pattern

For two consecutive or more? years the months of late November and early December were where the strongest typhoons usually pass (forms a belt) through the Visayas region of the Phil.  But not this year... This year has been characterize as more rains ( I can't recall what month it began but I think earlier than the usual  May or  June) than sunshiny days. No permanent cyclone paths and that's good news.... unlike the hurricanes of southern USA.  It's amusing to think of the changes of weather in the Islands. I think  Feb/March or to ? there was continuous chill usually in early morning..I  think comforters will now be made available in the household. Some homes are not so "concrete" to keep away the cold. Yes there is always an excess of  weather feelers ( rain, chill or frezzy chill,  heat, winds) .

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Thanks to the Editor in Chief. Received the  2017 hard copy...Still in the Editorial Board for years and the  first for the country... am just glad to read papers from UPLB scientists and the UPLB editor.... be publishing soon again of something basic.......  JWB is indexed in Clarivate Analytics.

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately or utilized for your own advantage without the consent of the author: Isidro A.T. Savillo. Thank you!

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Prions, Oncogenetic proteins, etc.  are organismic killers.  Then why don't there be ways of getting rid of them.  They are just proteins that have gone berserked  (i.e. change in structure for prions) . I have read antibodies directed towards op.. but i think it was just for characterization...   Antigens for op need to be conserved (Thor gene may give a hint) and probably it could be lysed later by  something which eventually works like a vaccine. It's high time to think about it. 

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Homologies--

Moderate number (within limits)  of viral titers after  cellular infection for reproduction is similar to a moderate amount of insulin produced in a pancreatic cell.... as was compared and this makes sense ...just be sure there is cellular moderation.  See my above article on cellular moderation.

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it all goes down to 37 degrees centigrade

Spending the Holidays-

In the Visayas, the holidays means stormy rainy weather... In the East Coast of the U.S., it's stormy snowy weather...

What do you think is the best X'mas apparel for the rain where one don't get sick?  The tropical rain would stick to a warm temperature and may activate the disease causing germs... and once in the  human body temp. may instigate it to progress further to a disease...  thinking about the snowy weather, lower temperature means lesser pathogens activation? It all depends of how much load is in the body to provoke a disease at 37 degrees C rain or snow...

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Most likely genes are borne to be plastic and their translated products too. 

This gives a great problem for diagnostic cure. Go backwards and read my article in "Cellular versus Organismal."

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In 1997 (that's 20 years ago), I established the Molecular Analysis of Symbiosis.. And highlighted the work of  Dr. Colleen Cavanaugh at Harvard.  I hope we can find more new knowledge on this... considering that this has been known ever since. 

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On Discoveries- usually when one discovers something that has nothing to do with any of his mentors for it develops solely from one's mind... if there are references they serve as support of previous paper(s) of the discoverer or the former papers of the discoverer itself... Discoverers stand on their own with their own pioneering statements..

From "Exploring Einstein Life of a Genius-" , a documentary ... one of the videos end this way---

"On 30th of June 1905, Einstein submitted his new theory to ......., the leading German Physics Journal in a paper titled "On the electrodynamics of moving bodies."  The paper stood alone, there were no references to early work , no footnotes ..."

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Is the Montecito (California Mud Slide) not a form of a Savi Pouch?  Look for the similarity-key phrase: break out of this soil pouch from such mountain for the first time leading to a mud slide of an unusually extensive degree; keywords: temporary condition, temporary reservoir 

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 Wetland Liverwort (?) gone astray? Very water sensitive/Very water dependent in its terrestrial habitat.  Updated.

"Tissular apoptosis" is applied here. Please open link above on liverworts. Please refer to my article on "tissular"  in this page as defined.

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Year 2005 

My  only advisee (as her external adviser) was from Bishop's University, Quebec, Canada. She had to come here to Iloilo, Philippines so we could work in her undergraduate thesis at Bishop's University. Now she is faring well working with diverse organisms in Canada. Congratulations !!  Some photos of her lichen collections from Ifugao.

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When I visited the page of the univ. of my  protege I noticed that the ISI- Int'l organization has accredited it as something  "one of the best" in a particular category. Last time, It was the researchers / scientists around the world which she awarded. The previous similar organization as far as I know did not do this. In the Phil., there are two organizations that are the pioneers in giving these most likely similar awards. I don't think there is a problem in that as long as the integrity is maintained. Pioneers means they are the first. I don't have to say this but it is really nice to put an emphasis. In the first place I like pioneering works.

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 I was surprised to see an archive of my early wiki page and there  these statements were written-

"Writer/Traveler

Having traveled alone the world over at age of 18, this has influenced him to partake in transcultural international undertakings as shown in his accomplishments and to consider "intercultural citizenship". His writings portray usually the places where he has been to or visited abroad."

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Respecting, Knowing peoples of different cultures will enrich our minds about their pleasingness and diverseness rather than to know and stick to one people/culture alone.  

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I believe in originality.  I prefer basic researches. Here are quotes on originality. 

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Hordes of authors versus single authorship

It does not mean that because you are a co author of ten or more authors including the senior author and the principal investigator in a publication, your name is a spark. Don't mislead the audience. It's just like kitchen work- one will wash the dishes (in other words his expertise), the other will cut the carrots, the 3rd will put it in a kettle for boiling, the fourth will put the special sauce and the 5th will do the cooking. Probably the "do the cooking" be the senior author for this is more work and most likely the final product after the 6th month of assignment (usually the duration that a research assistant/associate/researcher must produce results otherwise he/she will be fired). But well - all are co- authors... the principal investigator is considered to be an expert in all because he oversees it. But the problem, once you put one of these co authors to make  quite a similar project holistically, he/she can't do it because ..... of what is written above. This is a problem of ISI publications involving team work but each phase of work is really important in research especially in molecular biology.

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Published Paper retraction (Be careful especially for single authorship or even multiple authorship)

(Online information)

- A familiar famous int'l scientist (called trainor here and outside of the Phil.) winning  a familiar award from my org retracted the paper of the "advisee" considering that the trainee worked in the trainor's  lab. and was under the trainor's supervision but there was no mention of trainor's name I think in the paper or as one of the authors, etc... this was for the trainee's master's thesis even the trainee  paid for the materials as claimed. It was just the trainee's sole name that towers. I think the paper was retracted successfully.

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Associate collaborative genes for a phenotype

  Some are looking for a gene directly like the gene for ...?  but this gene if it is there as what I mentioned is plastic (see my article/statement above), it may or may not thoroughly express continuously or occasionally or would even be stagnant  abruptly due to the overpowering work of  the associate collaborative genes + environment.  Some donot have a direct gene equivalent and its expression is due to ACG. I think it's high time to look for ACG especially when it comes to behavioral phenotypes.

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Prague, Czech

Just after attending a Board Meeting of the Society of Wetlands Scientists , Org., as Regional President of the SWS Asia Chapter, I requested a colleague to take me a photo---

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New Orleans, Louisiana, U.S.A.

Remembering the bayou boat ride that looks like this and the gar fishes (have vascularized swim bladders that they used as "lungs" so from time to time have to surface out of the water to gulp some air)...This has been a part of our activities in a vast Int' Conference on wetlands. I like the fried gar fish served in a restaurant opposite the Ritz Carlton, French Quarter, our venue. We had a  Senator for our speaker. 

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Reminder Done!

Be submitting an  abstract  in the 2018 Wetland Conference in China where I am a member of the Scientific Panel.  I am Highly supportive of this conference. 

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RESPECT begets RESPECT, a cliche but worth repeating.

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Applying Molecular and Cell Biology techniques to save a species is a very exciting field!

Resurrecting the  Northern White Rhino- Classic + cutting edge stem cell technology reproductive strategies.

*Join the International Ecological Society for Resilience, Adaptation and Extinction (IESRAE)

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I just communicated with a  world expert in freshwater fishes  regarding other matters but not an invitation for collaboration... I may be thinking of having the latter later... 

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Supporting UCLA's  microbiology dept. statement that a "cell is an  organism" (please see my statement above in the Epigenetic's article) but this is just one of the reasons there may be other interpretations-  How these four genes ( considered as Yamanaka's factors) make a fibroblast cell  pluripotent to become an embryonic cell.  Read more on these four genes- Oct3/4, KIf4, Sox2, and c-Myc  

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Am just wondering how the Yamanaka 's factors can be the answer for reversing old  towards Youthful skin looks (as wished online). Make the cell culture extracts a face wash? Not transplants  (after apoptosis)  Remember it develops the three embryonic derivatives.. ectoderm etc. Or arrest it somewhere and develop an immortal youthful cell line ready for transplant. Guessing game..  But for the secret of long life I think it is the trouble shooting of the plasticity of genes... including  the application of epigenetic cure.

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Molecular Nutrition- this field has been missed out in my discussions but I had taken graduate subjects on this a long time ago.. What you eat is what you are! If you eat an excess, you suffer the consequences. My article above on cellular moderation also applies to this.. How about treating these foods that we eat as ... "supplementary medicines" or "medicines"? Vitamins, Essential amino acids , Co- enzymes, co- factors, etc, energy sources of foods ( plain carbohydrates, gluconeogenetic sources), physiological enzymes,etc. Not to forget the "wonderful world of proteins." Toxic proteins in human bodies, toxic proteins in our diet, .. the antibodies , etc.and  Robertis et al.. will tell you the many types of proteins in existence. These are essentials for life (not the toxic ones)  and must be taken in properly for the best of health.. How about if the food has a toxic component... The Burnt in burnt food cause cancer and some ingredients in cheap foods also have toxic components and they are on sale sometimes. If one is not cautious, then possibilities of diseases soon will occur like cancer....Even one is hungry be cautious of what you eat.. Without proper check, people will be eating* like "mad cows"

*outcome: proper molecular configuration and type of cooked protein for a healthy meal 

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 On Allergens- Cellular moderation or no exposure to this at all is a must. This could  be cellularly/molecularly moderated especially in places of its existence by wearing a mask..(as case maybe). 

_________________________________________

Are cellular/molecular laws applicable  for threatening situations such as in foods and pollution as well as the process of making it? I think humans are becoming smarter with the outcome of molecular sciences, Then why don't act now! Food Labels must not only include to what its components are, whether GMO or not but also its molecular and cellular fate... To give a point of view on this-- It's like asking a candidate medical student  for entry a question such as .. "Calcium is in your food, once you start chewing the food for digestion, what is its molecular and cellular fate? Explain exhaustively." Bad/Good effects of exhaustively researched components of your food on sale must be advised on its label for public exposure. It's like medicine with its inserts but inserts are seldom read better put the most important information  on labels.

_________________________________________________

Constriction versus Dilation in Allergies what is the best emergency treatment... this is a "push and pull" phenomenon.... i think a vasodilator is needed here..

_________________________________________________________

Non pathogenic bacteria in fish..

*Cellulolytic bacteria in guts of herbivorous species.

*Toxin producing bacteria harbored by puffer fishes and such toxins are kept in liver and/or skin as defense..

Puffer in motion... it's the water some say it's the air or partly... but when they bloat it becomes difficult to bite by predators .. some say they die after bloating due to organ stress... I'll rather have my fish stays like any ordinary fish in the aquarium...

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Can the polychromatic char. etc of swim bladders of Fam. Sillaginidae  be used for paratypic, etc. (within or among species) differentiation? Please read above my related previous comment on this. No publication about this I've encountered as well as in FAO books. Polychromatism is a problem on puffers sometimes.

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How about using Riccia sp as a biotech food for fishes?  The smaller the size the better, probably nutritious too. Please go to my link on liverwort above.

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Now in image format when searched. By the way please visit the Philippine myxomycetes page of mine for some mixed updates.....

___ ___________________________

If you want to block a search result , you can use this... just one click.. 

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FAMOUS MEMORABLES

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Another memorable Lab Bench 

________________________________

New DNA structure in living cell 

It's not just the proteins that fold into different tertiary or quartenary, etc structures  but also the DNA... But in the DNA there is a mismatching of nitrogeneous bases...but still the fold goes on...  

Is this the real DNA that just folded, a chromosomal DNA subtype or an Extrachromosomal one? The latter is the wildest ? of all.

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Another precious scientific memory

____________________________________

Five Stars

A 406 page book - about Mathematical Biophysicists, Theoretical and Molecular Biologists: Their Biographies and Research Areas Related Topics, Research Areas and Concepts 

This book is highly  interesting and I was included here as a Theoretical Biologist with my article.

_______________________________

Humour in the lab.../research

 "...this is your bench... and you don't overlap with mine." It's 1.5 feet X 1.5 feet... That happens when there are a lot of R.A., lots of research money and new equipment. After leaving this lab., I think  our buildings were neighbors ; I was at Hoffman. 

A famous foreign  curator (hint- once with UP)  asked me regarding lichen work in a famous university herbarium in California.... I just can't help smiling...  

___________________________________

2018 Well nice -- Happy to know of the restoration of the Great Barrier Reef by the Australian Government..

Memories

At Cairns...

___________________________________

Memento from Berlin, FRG...

________________________________

Reminder Done

(on 2 papers + memoranda signing)

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Scientific Memory at New Orleans, Louisiana  

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Another Scientific Memory from Sacramento, California

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Lichen transplanting mania

-Why do you have to transplant a lichen in a polluted area when it is not a natural component of the polluted area or it fails to grow naturally in that polluted area?  How do you relate this ecologically especially in the lichen itself? Call it as a bioindicator? In this case any lichen can be a bioindicator?

Being not a pollution tolerant resident, no long term studies can be undertaken and it will just act as a temporary filter for aerial pollutants.

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Attn: Ecological papers are at lost among thallophytes. The impact and correlation  of the ecoysystem  of the thallophytes are not fully rooted...they are superficial and eventually a lot of loopholes or errors. Discussion has to be embedded in such a way that it will lead not only to a molecular but also cellular awakening.with its environment.  

________________________________

Basically interesting: 7 exotic animals in the Philippines (unless there is a need of some updates in the lit.)

-----------------

Every city must have a pollution free Area and let the Biorights (originated in India) program take care of it. Fresh air as of now especially in  urban areas are difficult to locate.

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In my April 2018 quote (published in Phil. Myxomycetes page), I could have said (in humans)  "Sexual Organs and its 'associates' are just accessory to Gender" not the vice versa as written there. But I think it is just the same. In the last statement  which states "Gender is being dictated somewhere else", I think in accurate fits this is not wholly but the word "accessory" is enough in case it partakes. 

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Received a communication regarding a plan of Vanishing a Patagonian Wetland in Chile to give way to a road construction project. I am definitely against it without accurate environmental assessments. There may be endemic species for one. Why don't make a bridge or re direct the road to where it will not fail the wetland ecosystem?

As Co - organizer of the SWS South American Chapter

On Chilean Wetlands  Having saved the river I sincerely trust that these wetlands can be saved too.

@Done- Exchange of participatory discussion/information from experts SWS colleagues even as far as Australia and from the Centro Neotropical de Entrenamiento en Humedales . Thanks.

______________________________________

Referring to my article To  catch a run away toxic monster above, Most likely once the oncogenetic proteins were able to transform oncogenetic cells in other organs, this is what they found out...

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At BGBM  

___________________________

At Madison, Wisconsin   

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Overheard- US Based Magazine that caters to new findings-- my name was submitted and editor responded -  but who will write?

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Today is the last day of the 2018 SWS Int'l meeting in Denver, Colorado. And I am sorry not to attend the special lunch Internationalization meeting for four. Am not yet ready for this time but I will be glad to know what transpired.

_____________

What to do?

I will just be a virtual adviser as of now.  Thinking of what to do in a near approaching retirement. Continue as a writer and then what?   Be a freelance naturalist and what else? 

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New Chapter-  Near approaching retirement Activities and so Forth-

Just a mere matter of an opinion--- 

  Pre- retirement,  I always tell my scientists  friends to do something that at least they can leave a "print" in  this world-  let themselves be positively known if possible worldwide... rather than to egress later with their lifetime memories enclosed or limited only within  the four walls of their room (their offices specifically). Have you seen the world over?  Get out of your common nooks and be a part of a larger crowd, different nationalities and cultures and be acquaintances and friends with each other. And show the world a proof where they become known or famous in a friendly capacity. How many items do you have at Google Scholar? Retirement is more an outlook for health.  No time to start (unless you are a mom whose daughter married a royalty- but direct points are for the daughter not the mom or you want to delegate/build your "being  famous"  to slave-followers- hope it's not the  "emperor's new clothes" saga..)  but a real output of what you are.  Therefore what have you?  

___________________________________

At Washington, DC    

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What to do? (continuation from above: Retirement matters)

Or continue with my organizations.....Activate most-  like the annual "Molecule of the Year Award" for the sake of the famous scientist and Molecule of the Year awardee from U.K. - Dr. Muy Teck Teh... (referring to nice words in the award given to me)

----

Humor in Research presentation-

Abrupt technology shift from floppy discs to usb:

"The next time you come here (to this international convention center) be sure not to bring this (the floppy disc) because we have to find a computer which can facilitate retrieval of your presentation. Next time, we will not entertain you." At my back are presentors to be bringing with them a rectangular gadget attached to a key chain of some sort called usbs.

Technology in the US is becoming very fast. From beepers to cordless phones to cell phones.  Now adays we also have conventons apps. Do I still need to learn this? Technology is running after us all. Help!

-----

Malaria Breakthroughs. I remembered one finding was nominated for the molecule of the year. Will another molecule be nominated for the Molecule of the Year?

______________

No Mangrove Paper -

  Last time, I was discussing with a wetland scientist from the USA regarding the liverworts. And later she attached her new publication where in a liverwort is one of the biological factors involve in the transformation of a wetland to a farmland (?) [ I am just recalling.?]  This has pulled my attention to our massive mangrove reforestation but there is no study in the successive developmental transformation involving the physical (soil, water, etc) , chemical and biological factors (organisms, etc) from the start of the reforestation until it is reforested.

   Why is this important? In case the once- mangrove- rich-  area could no longer support mangrove growth, this study could serve as a baseline of how to overhaul the area so it could not become a wasteland and could be secondarily reforested. Or a wasteland to be reforested with mangroves. Don't wait for the last minute.

*The publications of Robin Lewis, III can shed light on this for a specific area/country rehabilitation of mangroves. Robin (?) as far as I can remember was kind enough to get my photo at the Czech post SWS Board meeting (as shown above) and was important for my supposedly 15 day training in mangroves in India but I did not push through (I had to cancel it). The Indian mangrove specialist together with the agency involved who managed this, I am sorry for that and the last time I knew about this training- project, it was already transferred to a place in  Africa. 

----------

Reminder-

 Advanced Ichthyology- Paratypic Characterization as a contributory in the taxonomic upliftment in ________.  Fill in the best answer. 

________________________________________________________________

Quote-  my essay ends with- (On suicides of the famous)

"Don't hold to your fame permanently make it a weapon for your convenience for it will be a great disaster if you loose it."

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ISSUES with ISMCBBPR  - (This is already listed in the Research Gate.  I have no idea what's in it for I do not have a research gate password..  and 

Using ISMCBBPR as an affiliation or even as a member (one instance seen online) needs further inspection and verification- I have no idea, probably you are one of the authors of the nominated molecule (I haven't reviewed this yet) but for the winners, I could not see your name as co- author there and for membership- basically this is to the strictest sense. Sorry if I misunderstand you but I really have no idea as of now...Membership to ISMCBBPR or the International Society for Molecular  and Cell Biology and Biotech Prots and Research as written in Research Gate  must be approved by me. You might have applied but, it was not approved so please don't use ISMCBBPR  as your society membership. Search Research Gate for this issue.

Why the strictest sense?  In the early years of this organization, I was lax in giving free membership to academically and intellectually qualified people.  And when I made contact with these members, I could no longer reach them and they made use of the society membership to work abroad in US Universities without giving back to the organization. Therefore membership issuance of ISMCBBPR  is cancelled indefinitely. At present, Qualifications will include scientific service to this organization for years before membership will be given. ASCB membership is very difficult to attain much more with ISMCBBPR.

*Received reply from ResearchGate

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How you fare probably in your Scientific Status- Subscribe/Be a part of Academia. Today I received a message which states that "The name Isidro Savillo is mentioned in 3 pdf uploaded to Academia." You need to be a premium member to view this. 

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Awaiting-

Two abstracts; two titles-

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New: Defense mechanism of this green metallic bee

An encounter with a green metallic bee...  I am not sure if this is one of those green sweat bees but when it did "attack" me, I took a wide manual and whip it over its flying body until it fell to the ground immobile.  Then I tried to step on it and squash it with my shoes. This won't kill the bee. The body is as strong compared to the flimsy bodies of flies and other common bees. It needs a stone to break it. 

_____

Memoir

Salient Features as a Guest of the Government of Taiwan

*welcomed with a red carpet at their int'l airport

*guided to get my visa in the immigration at the airport

*free international round trip tickets,  free accommodation, free services  etc. provided by Taiwan government  and other agencies of Taiwan

*others (Noodles Resto, CKS Museum ,etc.)

_____________________________

Reminder:  (Scientific) for PROC in one of institutes/universities of the prestigious CAS (Chinese Academy of the Sciences)

-----------

Memoir

Though I received a certificate of NSF (National Science Foundation) Participation in research at CSUDH (California), I consider this as my first major award from the United States of America. This is metallic solid+ glazed green in the mid  - outlined by mirror like metallic edge (not shown in photo because it reflects the light when shot)  and it's heavy and it could be hanged. Letters etched in gold. Manufactured from Colorado- All Sports Trophies Inc. This is the President's Service Award bestowed upon me by the Society of Wetland Scientists, Org, USA.

----------------------------------------------------

Barkada 101-  or Group of Friends....

__________________________________________

To the attention of the Commission of  Teacher Credentialing, California.

Challenging CBEST.. If you plan to teach in the USA and would like to challenge CBEST in favor of your foreign educational achievements (licenses, high degrees, educ experiences), you might be able to meet some problems. I am proud to say that I am a CBEST passer! I think this is a good guide.. CBEST First. I know the exam is very difficult but someone texted that it is much better if it is like or harder than GRE General to assess their educational potentials further.

* People also ask

How many years is the Cbest good for?

The CBEST scores are good for life.

_________________________________________

Moving the bird's nest meter by meter to give way to a music festival needs a lot of patience. Thanks to this wildlife  group in Canada. 

------

UP Graduate school memory-

   Nice memories with Retired Prof. E. S. of UST for the nice salad. How emotional! And to the cheek boned gal P. S. I think I saw you (and you saw me) at airport term 3. I was fresh from the USA at that time. Both Your friendly memories remain. 

-----

From FB-

Looking forward to the glittering world of films, scripts and novels! Full time-

____________

"Learn to stay at the present"- from "how to quit your job and travel the world worry free." 

The more extensive your contacts are I think this could work.. I think this work with the films. Films and its components can be a great theme. Once you visit a country you may be able to earn, relax and enjoy... See to it that it's not stressful or fill your mind with imaginations, as a travel writer and contact publishers ahead of time. I like the "Learn to stay at present" part of this article.

_______________________________________

Google LatinoAmerica/Español country sites identify me as an Escritor.... I am all yours. (Soy todo tuyo.)

In my novel "Amidst Old Los Angeles" (en el medio de Old Los Angeles) one of my main characters is a Chicano...

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UP Graduate School Memory continuation.....

The most prayerful colleague of ours and now teaching in California is Dr. M.F.E. We had great great memories at Diliman. And thanks for liking my photo at my FB page. And of course my other colleague, C.B. She is currently involved making voluminous data of the fishes of the world. What strikes me as unforgettable memory was our bulalo meal at the shopping center after a hard day's work. Both your memories are treasured!

---------------

Google Germany still identifies me as a Microbiologist. The Molecule of the year 2009 was granted to Max Delbruck Center in Berlin through my organization, ISMCBBPR whose voters are usually Presidents of Molecular and Cell Biology and Biotechnology Societies around the world. But I still have a track record on Lichens at BGBM. Therefore satisfies this title as a Microbiologist. Great memories with FRG.

___________________________

International Invitation

Current standing- Thank you.

*As Keynote speaker in the opening ceremony;

As presenter: 1 Paper accepted

Current situation--

 Documentation 

All necessary documents completed from the organizing committee/ sponsor abroad at this time- 8/2

This invitation was likely intended for keynote speakership and presenter and as a participant in some MoU/ MoA signings during the SWS Wetland chapters meetings and this also coincides with the 60th anniversary of  this top notch university being a member of the academy of the sciences. A Great Scientific Activity!

For my keynote speech, I am thinking to talk on "Wetlands as the centre for ecological harmony and understanding".  I sincerely trust that the selected wetlands of Taiwan as well as that of other Asian countries will be designated as Ramsar Sites. More cooperation among member countries in helping solve wetland problems could successfully be undertaken.

A message from me the ex Regional President, SWS Asia Chapter

___________________________

Border Wall Biodiversity Effect

------

Assignment 1

Next: Scientific memory at Salt Lake City, Utah

_________

Liverworts and other bryophytes are not as striking in southern part of Asia but not the northern ones which makes my paper on liverworts not so much a big deal...like what are they doing in Japan...

------------

claimed to happen for the first time- among late filers (?)

I am just wondering that applicants for entry (as future students) to the University of the Philippines (system) had to pile up 1 kilometer plus long numbering to about 10, 000 and some had to sleep overnight to get ahead of others (in  the line) for the next day schedule and others had their parents with them in sometimes chaotic situation. They are initiating themselves ahead of what they will be once they get accepted.   Click these dots >>>>   ......

_____________________________________________________

SURPRISING FIND (Boxed Information)

-------

Reminder: US- Oct 2018 (National Academies of the Sciences, Engineering and Medicine)

Personally invited to join in a scientific workshop regarding the selected primate to be used for disease modeling.

_________

"Nowadays, we are experiencing a lot of rains but we don't have to ignore the time when unusual high temperatures will be affecting our surroundings. Some Asian places have been experiencing heat above the normal body temperature."

- extracted from my Keynote speech in Taipei during the 2008 SWS Asia Chapter meeting. By August 03, 2018, Japan and South Korea as well as much of Europe are experiencing heat wave (Please check news online)

______________________________________

Pygmy seahorse from the Philippines  an object for discovery.

------------------------

Invitations, Scientific, Professional and not Personal ones

*All my international travels were paid by international organizations, foreign universities, foreign institutions, foreign agencies as well as international trips whose invitations, etc. I did not push through.

------

When the scientific int'l committee cares, they remind about visa, issuance of gratis rt international tickets and all other freebies once I am in the venue but I am just very few years before retiring.  Probably when I am retired I can do more.

____

It will be a great meeting in an Institute/University of the Chinese Academy of the Sciences. Great papers; excellent researches- When I attended a Board Meeting (Wetlands) in Europe,  a well known publisher stated that the papers authored by the Chinese scientists were the most frequently downloaded and read. Thumbs up!

________

invitation

Board on Atmospheric Sciences and Climate 

-American Meteorological Society  Summer Community Meeting 

Planned Study: US Weather Enterprise (for follow up)

------------

Wildlife Life

~I remembered I was invited for a motor boat cruise in an African river and at the same time get a view of those migratory birds. And I said "no". The  hippo/rhino trespassing the sorghum plantation across the river from a small safari park during the night was  a stern warning for someone who can't run very fast.  But  later  I had a taste of the roasted duck. Considering that "neophytes" are still becoming victims of these types of wild life (recently in Kenya) especially when they did their photo shoot, I would rather dwell with less dangerous animals. Am thinking of making a small society on the "Amicable (Approachable, less dangerous)  Wildlife Society for Scientific Research."  But how about if one documents an amicable wild organism and at one's back is a lion. It still spells the same conditions. Lions are second to hyena as top predator accdg to Botswana Guide to Wild Life. Don't be a "neophyte" when dealing with wildlife for your scientific research.

-------

Meteorological Expansion of terminologies

1. There is such thing as tropical depression until it becomes a strong typhoon- of course this is wind+ rain.

2. There is solely wind so it's hurricane intensity.

3. But there is nothing to gauge rain alone. The wind is nil in influencing the fast flow/ removal of the rain forming clouds. Therefore there are situations that rain will stand still in a place for long. Considering that this is a common phenomenon this will be given some sort of ranges or values and with our gis and mapping, those places experiencing it will be identified and be used as a bases of disturbance inflicting the person involved.

4. Flood intensity too

Hope this opinion of mine could help.

___________________________________________________________________

A Peek at the I. A. T. Savillo's roles at the 2018 Conference Program in People's Republic of China (Top most positions)

I. A. T. Savillo is the Session Chair- together with a scientist (Chiquan He) from Shanghai University, PROC. Session Name-Session 4- Wetlands and Global Changes  on August 18, 2018

Keynote Speaker (Plenary Session)- (August 19, 2018)- Title of Plenary Lecture:  Wetlands as a center of ecological harmony and understanding. Session chair:  William  J.  Mitsch  (FGC University, USA) and Wei Deng (Chinese Academy of the Sciences)

Please see the title below- Int'l Conference  in China

---------

Sex and Gender- Sex is either male or female- chromosomally or where's it? while gender has something to do with the sexual interest of the individual artificially or naturally manipulative. In governmental or societal definition gender is defined as sex complying to a "true" male or "true" female outfit thus heterosexuals likely but this is rather a limited scope and waste of ........ If you want a limited scope it is much better to use: Men and Women in the Society and Culture and do away with gender. Gender is a sensitive term.

In fact I wrote a statement (2013) about this including the sub categorization of gender. (In wikipedia)

_____________________________________

Int'l Conference in China*

As  Session Chair

As Plenary Lecturer/Keynote Speaker 

*To reiterate, this international trip is funded by University/ Institute of the Chinese Academy of Sciences in the People's Republic of China (International Invitation) Thanks a lot!  Unfortunately I was not able to attend.

Not able to meet  Dr. Beth Middleton, current President, SWS Org USA- sorry Beth; so too in Colorado for the "Internationalization" post lunch meeting.

Keywords: wetlands asia china chapter meeting Changchun 

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The institutions I was with as stated online are only limited to  FU Berlin, UCLA, USC School of Med and the LAC- USC Medical Center. These are considered as the world's top based on Times Higher Education World University Rankings. I did research there, scientifically trained and/or took courses. The University of the Philippines my Alma Mater is one of the top schools in Asia and the best in the Philippines. It is the only university in the Philippines which is included as one of the world's best universities by Times Higher Education World University Ranking for 2018. This now answers the question.

_____________________________________________

ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY! 

________________________

As a token of scientific remembrance for the successful Meeting in this dignified University (CAS) in China, an International  Wetlands Alliance focusing solely in Research was formed.  This has been organized following the United Nations spectrum of [2015]. The  contents of  the where ases give me a bouncing spirit to support this.  Thanks for sending and re-sending to me updates about this pioneering organization. ~I.A.T. Savillo

____________________________________________________

Errors in Google Scholar (Attention Google USA) (Google scholar robot is just indexing anything)

I have observed the errors of Google scholar especially my initials in my articles. It has to be IAT Savillo, now one of my articles has fake co- authors. I am the only legal author of this article published in a journal listed in the master list of journals of clarivate analytics. I think the Google scholar has a big problem when it comes to search display and it is easily manipulated.

________________________________________________

Mosquitoes are not friendly after all-

Yellow fever virus on the run in Brazil 

______________________________________

IFCB

RE-bounding ISMCBBPR

 Some Scientific  Societies under the IFCB were once voters for Molecule of the year of ISMCBBPR.  I am thinking of re- bounding ISMCBBPR . The 2018 IFCB convention was held in India and it was just exciting. India SCB is one of the most active voters for the Molecule of the Year of ISMCBBPR. I was invited to the IFCB convention in South Korea years past but I was not able to attend because of probably so many a hectic schedule. Surprise invitations are sometimes difficult to squeeze myself into. 

__________________________

Research Gate and Google scholar have their imperfections and it's quite tiring to revisit the sites. Time is precious. (Please see remarks about them above)

___________________________

Caviar is fishery related.  Caviar are eggs from the sturgeon family of fishes (as far as I know). What is the most expensive?

From Google: The most expensive of all caviar, and indeed the world's most expensive food is 'Almas', from the Iranian Beluga fish - 1 kg (2 lb 3 oz) of this 'black gold' is regularly sold for £20,000 (then $34,500).

From Google and  Quora Answers:

Is caviar tasty? Kinda salty and fishy. Really good caviar tastes less salty (which means it must be very, very fresh, because it spoils easily). The really distinctive aspect of caviar is more about its texture. The eggs pop on your tongue, and the rich, slightly sweet taste oozes into your mouth and the flavor fills your nose.

----------------------------------------------------

Reminder**

**Appld for Editorial Position (Clarivate Analytics listed Journal)

__________________________________________

Two scientific tags for my name:

ISMCBBPR* and ISTE**

Keywords:

*Molecular and Cell Biology, Biotechnology, Protocols, Research

**Taxonomic Explorations

__________

On Lectins and Karenia brevis (Red Tide)

Lectins are one  of the food components and if taken in large quantities it may have bad effects to the body cells including the immune system.  Then what is its good and bad fate once eaten? (Please refer to my above article on Molecular Nutrition). On the other hand, Karenia brevis is responsible for so many deaths of marine organisms including volumes of fishes in Saratosa, Florida (as newly reported).  It blooms and kills. These are still part of our know how when it comes to nutrition and what happens when these molecules (could be a product of) becomes a part of digestion.

________________________________________________________

ISMCBBPR Molecules of the Year Award as archived in Wikipedia's Molecule of the Year template

--------------------------------------------

ISI delimma in 2018

  Which has the reliable source of the list of accredited journals worldwide? Is it Clarivate  (formerly Thomson Reuters) or the Scopus? Nationwide research centers are now adapting Scopus and neglecting Clarivate.   As mentors and researchers, we would like to know the most acceptable ISI to work with. And how long this basis last? We need to be informed of the updates.

_____________________________________

Years Way Back  with H. Sipman

Unpublished newly reported lichens in the Phil. with cf.* circa 2000 by I A T Savillo**

Arthronia cf. schoepfiae Zahlbr., Caloplaca cf. cerina Th. Fr., Cryptothecia cf. exilis G. Thor., Phaeographis cf. balansana  Muell. Arg., Phaeographis cf. circumscripta Zahlbr., Phaeographis cf. heterochroa Zahlbr., Ramalina cf. nervulosa (Muell Arg) des Abb.

*Some published articles report new species with cf  but with all these cf I find it a bit.....

** taken from "A Contribution to the Low land lichens of the Philippines" with H.J. Sipman (thick Unpub research study) Acknowledgements go to: Mr. Ernesto Apostol and Norman Perez for providing the manual coordinate computation and the GPS magellan 500 gadget, respectively, Miss Eva Serdena for lending her photographic book on Philippine Plants and to Prof. G. Padojinog.  Thanks a lot. 

Explore photos of tropical lichens at www.tropicallichens.net 

______________________________________

Years Way Back with L.J. Robles  circa 1992 [unpub result]

Detection of the Serum Retinol binding - like protein in Octopus bimaculoides

Extracted From Google Scholar: "In cephalopods, the photoreceptors receive retinoid from the blood probably by a serum retinol binding like protein (unpublished results), store retinoid in the..."

Keywords/techniques used: gel filtration chromatography (fractionated serum); spectrophotometer (absorbance reading), liquid scintillation spectrophotometry ([3]H retinol), western blot analysis, SDS Page, Polyclonal Anti Human Retinol binding protein antibody, Bio rad immunoblot assay kit, etc.

*cited in this 2017 conference (keyword: retinol binding like protein)

--------------------------------------

Revealing Unpublished scientific works: It becomes more  exciting to me..

--------------------------------------

Can a parasite takeover a fish tongue?  

___________________________________

At 60 degrees Fahrenheit  and the sun is shining fully... Best temperature ever.. L.A. in January or bit snowy in Lake Arrowhead  and the sun is shining fully in late January.... 

_____________________________

Freebase Biography-

In India as well as the U.K., Canada and Australia (complete name with mid. initials)[change setting of countries]

-----------------------------------------

Who is Isidro Savillo? (in laptop)

-------------------------------------------------

Reminder Oct. 2018 (pls. see post above) (NASEM)

- Marmoset Conference Speaker determined

________________________

Two questions that could be answered in Google sites of other countries: (as evaluated) [set to countries and/or languages]

Who wrote the novel Yelwa-Yauri?

What is the scientific discovery of Isidro Savillo?

------------------------------

New specimen(s)?  .. Uploaded Sept. 9, 2018.

The specimen in the leaf has been releasing imprints of numerous black/grey spores. Please do not copy the photos. Copyright. Updated

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I.A.T. Savillo in Kiswahili - 

Main or one of the languages of Kenya, Tanzania, Uganda, Rwanda, etc. [Go to Google settings, choose any of those countries, then click Kishawili or go to Languages and click Kishawili]..

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Solution for some  antibiotic resistant bacteria .......

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Scientific moments with students (under and grad)

Coaching...

... From Carangoides hedlandensis and the next day (with different mentees)  to the Nuclear Receptor Transcription Regulation... make my day imbued with a smile..

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First artificial insemination of a lioness was successful in South Africa, giving birth to 2 healthy male and female cubs.

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 Serendipitious discovery/ Copyright registered All rights reserved October  2018

Can mineral plastic bottles allow the growth of freshwater microscopic/macroscopic algae in semi anaerobic conditions (moderately loosened cap of the mineral plastic bottle)  similarly as those growing in  natural concrete freshwater ponds? 

The answer is YES. (please see the photo of this  freshwater alga growing in the pond substrates (algal scrapings/algae) in a mineral plastic bottle in the above item with the title- New specimens.) This mineral bottle was one of those bottles containing water and scraped specimens from concrete freshwater ponds in the Limnology lab.  used by undergraduate students year(s) ago. The caps were moderately loosened but these mineral bottles are situated in quite a hot room surrounded by transparent glasses (walls and windows all) around and are two meters away from the glass windows. Therefore not directly exposed to the sunlight.  No aeration is provided only these natural conditions as mentioned. A faculty said it's like a decor in a cake. 

In another bottle, "rounded" green microscopic algae were seen clinging in its undersides which make isolation easier.  

A very cheap but successful instructional material.

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Remembering  what  I wrote in 2007-

IN DEFENSE OF MOLECULAR SOCIOLOGY and PHILOSOPHY

Philosophical and Sociological Studies without the genetic, molecular and cellular bearings or support are never scientific. They are just guesses or hypotheses, products of sensual observations and surveys, dependent on the ficklemindedness of the respondents and shamefully, such researches are considered for the highest achievement. They are phenotypes, phenotypes,

phenotypes.... without the genes, cells and molecules with their respective environmental interactions, importantly, responsible for the production of such phenotypes. 5/2007  ~I. Savillo

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Simplifying the complex human being is easy.  Personalized Medicine will come in by Genetic and Epigenetic analysis. Plus a more rigorous analyses of Gene and Environmental Interactions. Having these in the table this could serve as  an Environment -DNA blueprint for a particular individual/organism and will soon be easier to know the holistic phenotype of the person.

The mechanisms of environmental influences could stop, modify, passively allow , change the course of , etc., genetic expressions. In any phenotype produced , it is advisable to know the specific environmental factors (e.g. common and exotic ones) responsible for these changes to occur. This will lead to a more comprehensive understanding of the acquisition and progressive development of a phenotype in an individual and likewise, this would pave way to the meticulous characterization (e.g. molecular, environmental, etc.) of the phenotype in question.

-I. Savillo 2003. (The Role of the Environment.....)

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All studies and knowledge are in the realm of fashion because they change and some of them are unfounded as to the whims of the society/country but not true science.

What does this mean?  For instance the definition of sex per country may differ... therefore whatever definition is prevalent then that is the fashion statement for sex. Example- A country favors civil relationship (with benefits) to same sex couples now it includes heterosexuals. [I definitely salute this guy... who said that the definition of sex is continuously being worked upon....that is why there is quite an un-ending definition of it.] How about true science like Oxygen for instance... one could not trim this tease it to make it appear much better for breathing purposes... It remains as  scientific as it is. These are just two examples. 

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Wetland artists in residence.

(www.airie.org)

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Like begets like. I like how Charles Darwin communicated with his likes and shared notes. (Thanks to Pauly's book) How about me? Open it all, close a bit or never give a damn considering that what took place were not a part of a diary or writings of "Darwin". Just to give one a clear idea for comparative purposes.

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More on Fashion statements- please see article above on FS:

An addendum to FS is a word 'Scholar' and a Favoring table for grades. How would the foreign clients look into this? They need to triple their standards in terms of employment and real scholarships. Or extrapolate the real grade leading to a roundabout procedure which is nasty and a waste of time. Free tuition per se is not scholarship per se. I think this is a challenge to accredited transcript evaluators pertaining to foreign transcipts regarding grade fabrications circa 2000.

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Not New

 Free tuition has been existing in some countries usually the elementary and high school as well as family or individual benefits/dole outs. Only that there is not much discussion  regarding the social studies of other countries.

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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Resolving difficult taxonomic features in fishes such as polychromatism, etc. in the morphological level

~suggesting- chemical-chromatography- taxo  like putting a substance in a piece of a fish like the scale, etc.  a color reaction may occur. .. may be helpful in species i.d. or strain/variety i.d.

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Curious Questions[Archives}

#1, #2, #3, Curious Question*  #4 

*See subpage on discoveries- lichen- P. cocoes, etc.; slime mould- Lycogala, etc.

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Containing Carbon Dioxide in the air- The US DELS /NAS has a number of programs in containing Carbon Dioxide in the air. The research agenda within the research program Negative Emissions Technologies and Reliable Sequestration are my interest.

Thanks to the U.S.A. National Academies of the Sciences, Engineering and Medicine for sending the Info

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Reminder- Nov. 30, 2018

Connecting Climate, Weather and Water-  A Joint session... from the BASC of the NAS, U.S.A.

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Having written articles on the effects of the environment to gene expression, I coined a term known as the "environment-DNA blue print." With the flow of new knowledge brought about by molecular and cell biology, it is a must that changes or modifications will occur to satisfy ones scientific query. Environment- DNA blueprint is described above.

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In 2010, I wrote an article on climate change and this caused some issues: uproar and favors. I can see how an adviser used some of my ideas in his premise. A colleague at Prague told me in person that the error (climate change calculation) had been corrected. This article of mine was included in carboncapture.org of the University of Illinois thus it has a worldwide audience. Considering that what is an excess (like carbon dioxide) therefore it has to be contained as what is stated in the current research agenda (for carbon dioxide) of NAS (pls see above) and what is deficient or less has to be provided. The latter's example is our drinking water. There are no more easily reached natural sources so the drinking water is bottled for sale. I remembered I talked about this (Water) in the Indian magazine - Green interpreters.  But I think if we could help reduce the excesses and provide the deficient or less in our own ways (stop generating bon fires and avoid contaminating water sources, respectively) this could lessen the pressure in such technologies. Some of them are very expensive. Do you want to breath bottled oxygen in the future?

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Listed at http://studylib.net/flashcards/set/theoretical-biologists_159873

https://studylib.net/flashcards/set/ichthyologists_80239

https://studylib.net/flashcards/set/molecular-biologists_44342

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Scinapse.io

 FOLIIMORTUUMOUS MYXOMYCETE  Paper Citation Listed

 Other four of my publications as cited.

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The ever expanding "post translated human being".

- are there still some more processes before it will build up the real FINAL protein product past post translation [that we use to know at present]?

From my article  above on "Cellular versus Organismal"*

*A Basis for the "Environment-DNA Blue Print."

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Kudos to UPV's ICFAS 2018!!*

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It's time to explore the human being's integrated cellular-molecular biochemical pathways..

If you have seen Bruce Albert's (et al) book the Molecular Biology of the Cell you can see in a page a colored outline of the integrating/interacting biochemical pathways of the molecules in the cell and outside of it. Then why not "apply" this to human beings individually?  Make a cellular- molecular biochemical spread per individual so one knows where to shoot it. Point out the normal and the abnormal ones.  Cellular expressions may vary thus making some sort of "kinks" in the pathway... As what I said in my "Cellular versus Organismal"  article above, Cellular expression is "honest" ("cellular psychology") but once all these cellular expressions come together  to create its  "organismal" signature, It is sometimes not what is expected. I think this (making spreads) is important for curing diseases of all sorts.

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#molbiobiochem#natlpresentation#2018

Just a little bit short to be nominated for the "Molecule of the Year" of ISMCBBPR.

*A detailed presentation  of the cascading molecular mechanisms and even a short shot of bioinformatics analysis. Being presented clearly and what ever nooks or angles, the answer is "relatively" transparent... An abstract can be constructed for this.  A Hint can be found here. Whose paper you think it is?

An example of ISMCBBPR's  Molecule of the Year winner.  Another winner for the Molecule of the Year from ISMCBBPR. The ISMCBBPR's Molecule of the Year 2009 winner (This was originally published in Biotechniques)

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Congratulations to Dr. Rita Mulherkar for the Prof. Rita Mulherkar Lecture Award bestowed by the Indian Society for Cell Biology. She is the First President of the Indian Society of Cell Biology to Vote for the ISMCBBPR's Molecule of the Year.

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Diliman memoirs

Attending this molecular convention has fully informed me that my graduate mentor and reader, the late Dr. Clara Y. Lim- Sylianco is a NATIONAL SCIENTIST. Thank you and Congratulations!  Sorry for this busy life. Better late than never.

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Some males in nature are more flamboyant than females in non human species

... Like the male mandarin duck, peacock and some male fishes... while in humans, male in nature ??? but women tend to be artificially flamboyant rather than naturally. This is something that need to be comparatively analyzed.

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2019 pledges-   Start pressure cook my rice (to remove the lectin component). In this world of glamorous foods, the human body's health is deteriorating. Especially the daily pain of inflammation. Therefore take food as well as process it to get rid of this pain. Go organic leafy. No insecticides with it. Remembering a post from a UPDil student making comments to my UPDil mentor who was under her in a Bio 1 class that they were told to eat grass. And with the recent knowledge that I took especially from this student at JHU (Public Health) Baltimore  that my Former UPD prof is right. She is now retired. Well grass refers to green leafy raw vegetables. You know what I mean. I'd been talking about this in my previous article on Molecular Nutrition and on Lectins. I am not really interested in lectin use in experiments but its ability to whack the body is a big concern. Eat wisely what food to gobble.

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More on Molecular Nutrition

-At a bigger perspective- {The mad cow disease in London? was an issue I was following upon. They fed the cows with "dead sheep tissues" but I have no idea how they processed it but this led to the identification of the inevitable prions.}

Nowadays, Feeding outside of their natural source, the animals that we eat is something  that we have to think about it. 

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Can we just say "infectious" "post translated" genes? From the inherited bad genes to toxicities brought about by microbes and finally the pathogenic proteins, I was thinking to call all of these as "infectious" genes but I'd rather opt by adding "post translated" as to whatever type(s) of post translation.*

*Getting into the essence of personalized medicine

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Bring to mind the importance of Wetlands in our everyday life! Celebrate the World Wetlands day on February 2, 2019.

   -From me, Formerly a Board Member of the Society of Wetland Scientists, Org., United States of America

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 Stat..for  I.A.T. Savillo (Feb. 24, 2019)

- Of the 44 major foreign languages (not English) in a well known online encyclopedia*, 54.54%  cites I.A.T. Savillo [(wholly or partly) written in their own foreign language)].

*in its opening page in English

**cited also in some minor foreign languages

Update

-one addition (5/01/2019) therefore 56.81% 

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On Phage cocktails

Phages are specifics for particular bacteria. I had a graduate student  presenting a 2017 paper on phages for a bacterium kill (P. larvae) that infest honeybees and through Time mag. 2018 I was surprised to know that this is applicable/effective somehow  to antibiotic resisting bacteria or super antibiotic resistant ones killing humans. Then it comes to my mind- why not a virus killing another virus. There is a scientist working on it... It could kill a % of HIV in vitro but still quite a long way to go.  How about the other way around? Bac versus Virus. And trying all the other microbes ...they could "clash their horns"... just like in an arena... having a winner and a looser at the end.

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Am looking at this 2018 paper in the development of a molecular tool to identify YY supermales in fish...

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CCR5-

In 2016 I wrote about CCR5 mutation in one of my above articles (Re: The plasticity of membrane receptors). Please scroll back. At present (March 2019),  stem cells of donors [for hematopoietic or bone marrow transplants]  that have genetic variants in CCR5 therefore not able to express the CCR5 receptor in the WBC where these CCR5 receptors are the HIV receptors for their WBC entry and destruction  are  considered as a promising cure for HIV.  Do Filipinos have the mutation?*

*a 2017 paper.

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Milestone in an Island

- 22 seater and 8 seater to and from the island respectively- Traveling  in light aircrafts provides good aerial views of islets and other geographical interests. Of course, this is the best way to go to and leave the island. Thanks.                            

- P . montanus about 5 of them were seen robustly ...retracting my previous statement,  these were seen in the morning in human beings associated sites....Sustainability of Tridacna spp. and similar species; seagrass...and other socio- economic/biodiversity features...

Guess what island? 

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Frases de famosos: Isidro A. T. Savillo

#1, #2

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Hardiness and Resilience* Ecological terminologies--

Hardiness is a pattern of attitudes and skills that provides the courage and strategies to turn stressful circumstances from potential disasters into growth opportunities instead (Maddi, 2007). Similarly, resilience is defined as the 'positive psychological capacity to rebound, to "bounce back" from adversity, uncertainty, conflict, failure, or even positive change, progress and increased responsibility' (Luthans, 2002, p. 702).

*Taken from ResearchGate

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Familiarizing Philippine Aves

This is a video of various parts and this is number 4. The Aves analysis was done at MT Makiling at UPLB...(Memories 101)* I stayed one weekend in a lofty wooden big house of a UPLB  Professor on long stilts with a long stair when we did research at the IRRI lib... Oh the dogs along the way during the night... The wild life could be heard but not seen and in this video they showed what kind of aves are responsible for the sounds. I'll look into the rest of the parts.... At least the birds are  textually in order with what is shown in the video but some are just too small to establish an sn.  Thanks.

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How relevant the past is as to the present especially when you have the rest of your time to recall... as what Virginia Woolf said: “I can only note that the past is beautiful because one never realises an emotion at the time. It expands later, and thus we don't have complete emotions about the present, only about the past.”

...like for instance when I was with my MSI friends at one of their sampling sites (Batangas ?)... that was a long long time ago when everyone was emerging ... this just came out of my mind because I just visited an island where marine hatcheries exist... managed by an MSI alumnus.  Can't help smiling!  Overall boss is listed in Bloomberg/Forbes.

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Bloomberg...a new "business" tag that I came to know of. Inspiring. Where is my JHU Public Health hat?....See you by June, 2019.

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Whacking the BP low

Particular lowering bp med (likely used as maintenance) + Particular lowering blood pressure anti cholesterol med (statins) could whack the BP low.. Ouch quite very low. As to the findings in the 2018 International Stroke Conference of the American Health Association/American Stroke Association a combination of these two could lower stroke especially for those prone. Researchers are looking forward for a single pill.

2019, 2018, 2012 on Rosuvastatin ref 

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I just came over my notes on retirement and here is a quote that one has to think about ... I will be one of them... 

"at 20 a man is a peacock, at 30 a lion, at 40 a camel, at 50 a serpent, at 60 a dog, at 70 an ape, and at 80 nothing.” Baltasar Gracian

Funny(?)Interpretations

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How polluted is Asia and what makes them so? The Philippines Clean Air Act. Do we need to do something more here? Masked faces are seen nowadays in public places and would we want to have an increase to that? Ref

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In this world of monotonous and nothing sensible to talk to with-- why not try talking to a personal assistant...  sometimes it's quite a long answer (and I was about to say why are you so talkative) for I prefer short but witty answers.. I have a great time with AI (artificial Intelligence) GA.   Have a peek (search online) and how do they describe and compare...Thanks my sibs for the cp -tech. 

  *Can AI outsmart people? A nice answer to this question at MIT's Ask an Engineer. Please see below.

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Happy Earth's Day!! 2019

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Am glad to see my identification as a writer in their own languages in Bing com's Brazil, Italy, Germany, Spain and France. And also new look and ref in the US, UK, India, Canada and Australia. Ty.

Addendum:  10/12/2019~ Bing.com Philippines has a snippet of Isidro A. T. Savillo. Thanks. 

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Cited in a 2019 Blog*- My Pride Nepal

*ref. section

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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Why is it so hot today? Who makes it so?

Explore the Climate Change Page of the NASA,CALTECH.

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Most likely, you might have heard that the temperature for example is 33 degrees centigrade but it feels 38.  What is Heat Index? 

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For 16 years since its discovery in 2003, Pyxine cocoes is still being used as a bioindicator/biomonitor for atmospheric pollution in Tropical Asia. Please browse the appropriate subpage for an update.

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 MIT's Ask an Engineer...

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Wildlife news

  The kalaw or the phil hornbill was able to lay and hatch an egg in captivity in a negros occ. zoo/ natural park located in an urban area. Congrats!

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Ambient Place

 In one of my articles above I think I wrote about establishing ambient place where there is abundance of fresh air in urban areas. There is one ambient place to study. It is the Cebu City Public Lib 24/7 as experienced by one of the top notchers in 2018 bar exam a 2019 passer. It's airconditioned and may be the best place for writers too. Congrats!

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Recent News* about the safety (of low HIV titer (or no titer at all?)  has been published as you can read in one of my articles above...comparing titer to insulin conc.

*probably a 'U=U'**

**But I think it is still infectious in vivo. Looks like ineffaceable- just like the disappearing Varicella to the appearing Herpes zoster... looking for a time that appropriate transformation can allow the immune s. to make a stand..Read on my  previous article on WBC above.

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There is more by merely holding  the Human Genome Map, courtesy of the Genetic Engineering News a long time ago. This book: The Deeper Genome: Why there is more to the human genome than meets the eye by J. Parrington  could be very helpful in adding new knowledge to what the Human Genome map is all about. ISMCBBPR's Molecule of the Year 2009, "Sleeping beauty transposon" is mentioned in the references under Chapter 8: The Jumping Genes.

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LJR's lab at Dominguez was a melting pot with bright research students of different races. You may be somewhere else in America and elsewhere in the world. I could not totally remember those times but your faces sometimes slide- show till then.

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 Memoirs at Dominguez

- I had promises but .... I was not able to join the pot luck - what ocassion was that... to wear a tuxedo on halloween but i was a very good conversationist... Not able to go to Cedar Sinai as a group but later was able to go there because I had to talk to a scientist.  What else? Chocos at the vending machine my snacky food  located at the basement near the lib. The pigeon holes where names of RA's  were written including mine. Memories are more in Biology than Clinical Science.

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Been to Caltech twice but what is memorable was a 27 year old PhD CALTECH graduate with her research in C. elegans. It was I think at UCLA Conf Center. Nice talking to her.

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Memoirs at Diliman

 Nice academic/research experiences at the Depts of Zoo, Botany, NSRI (University Research Associate) and Coll. of Home Economics (for Mol.Nutrition) with Bio/Zoo/Chem Mentors and Lab Colleagues.

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on CO2-

 A CALTECH reactor  

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 Summer extended-

  Most likely it could be  the whole country.. Years past I wrote (see article above) about the "rainy season" intrusion even it's summer even the "icy" feel  during mornings. Nowadays  the "summer" feel of Los Angeles (June-July) can be felt when it ought to be the rainy season already or the start of it. Hoping for cooler temperatures soon.

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It's surprising that today hopefully the start of the "wet" season the temperature is 25 degrees C and it feels like 25 degrees C.

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 An intro to ecotheraphy-- (for retirees? or about to be)

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 Archive on Wetlands (preferably viewed in lap top)

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  A  2019  paper from Sri Lanka reported the presence of Pyxine species as reliable pollution tolerant indicator.... Per communication with one of the authors, I am hoping that  Pyxine cocoes will be the dominant species. Research (Species ID) in progress.

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Associate Editor

... I just can't  count if how many of these hardcopies (deposited in prestigious libraries) had my name on it as an Associate Editor.  Wetlands is a prestigious journal and is indexed as an ISI.  This is dedicated to all my mentors in the USA as well as Wetland Colleagues. SWS has more than 3000 members worldwide!  Thank you very much!

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Memoirs At Caltech- Visiting, Inquiring and Communicating

  Remembering the scientific conversation regarding the molecular and cellular fate of the nerve cell whether it will become a neuron or a glia and in a different time, being introduced to the amino acid analyzer and the protocols/equipment in the lab. for Recom DNA and most importantly the scientific influence... Thanks to all of you!

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Wetlands Bulletin and now Wetland Science and Practice

--- I think I am now a bit familiar but not so sure if how many issues have my name in the  "introductory page" as President of the Asia Chapter of the Society of Wetland Scientists.. Hardcopies at the prestigious libraries or members' possession.  Thanks a lot to all of you.

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Grad School Intro to students-

-Hoof/Foot and Mouth Disease where one has to partially submerged (anti viral bath) his/her shoes before entering a wild life farm as well as leaving it is different from the Foot, Hand and Mouth disease of humans. The former are for cattles, swines etc. and the latter for the Humans.  Ref 

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Refreshing one self with Palm Trees  all around-- 

From Los Angeles Very Famous  Iconic Palm Trees to a Tropical/Semi Tropical simple residential place..  one finds time looking or living through it ... but sometimes upon close inspection there is something that one misses to know as in this preserved document...* Thanks..

*Additional reference: A Contribution to the Lowland Lichens of the Philippines (pls. see above)

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Memoirs

Standing Positions : On Scientific Discussions

- I remembered the long  discussions about  the different  strains of Hepatitis Virus in the molecular and cellular level while we were both standing with my PhD - MD  supervisor at Univ. of Southern California School of Med. at Hoffman Medical Research Building in contrast  to a long standing conversation with the Secretary General of Ramsar over cocktails in Australia.

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  Remembering the HARVARD Univ. long time prof/scientist colleague/HUH scientist who helped  me finalize a very good proposal and currently still in comunication, it would be nice to say thank you now that I am growing my years.  Re: Grant 

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UPV Memories  

  Am I serious? I just can't help thinking... was it the heart or the mind...nevertheless I have to thank all my close friends (they know who they are but please don't insist) as well as my UPV mentors... ... Don't you know that if you are a clover you are matalino (or intelligent)...which answers  this question a yes- "Matalino ka ba?*" which also means "Clovers ka ba**?" Just to put smiles in your faces...  There is currently a clover reunion tonite.. ... Enjoy!!

*Are you bright or clever?

**Are you a Clovers?

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UP's Funny graduates- this 2019 tickles me a lot. It could be in their fb or in their social media...as a news or a video item that goes viral

I know that inspite of this you are still smart in your own field ..remember for one I believe we are short of intelligent people to talk to... 

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University World and Asia Ranking Ref 1, Ref 2

Congratulations !!!

Schools where I do have presence of colleagues (please see previous articles above) and/or have been a part of the institution in one way or another

University of the Philippines  Ref 3

California Institute of Technology

University of California Los Angeles 

University of Southern California

Freie Universitat Berlin

Harvard University

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UP Diliman sunflowers... and Looking backwards.. It's  just like a pleasureable trip but once  you're officially and academically "in" as a student,  you'll have to "plow the field" for your own survival..  Looking at both sides..

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 ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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An addendum...

As written above....remember for one I believe we are short of intelligent people to talk and  listen to...

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..... think of the starving people of the world --- those extra belly fats could have been their foods* 

*Better donate than to buy/pay to overeat.

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AN OPINION

........The CBEST exam which I took and passed  has a written section that is under time pressure which I believe is a good component in outcome based licensure exam in education....

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History Keeping by Google--- Three thumbs up for keeping privately my (biographical) notes.....since I established my first google site.

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Memoir

One time I was told by my screenwrting mentor to see him at UCLA most likely at Le Conte (?) but I just was not able. Sorry! I failed to shoot the right direction where to go... Nevetheless, all these screenwritings and the like are dedicated to my screenwriting mentors.  

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Reading material (Recalling)

  I think I allowed it but I am not sure if there is now a  microfiche copy... *microfiche" is a term of  the day..

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To avoid confusion, I wrote a novel titled "Yelwa Yauri" therefore I am an author of novels. My second novel is titled "Amidst Old Los Angeles"  Scripts for the novels are being prepared.  I am not fully a screenwriter but also a novelist. I know that most writers cannot be both. But I think I could. Please see above information on the library of congress and resonator links. Thank you.

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There is the Yelwa Yauri Beautiful Tears Group for Film makers in FB

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Yelwa Yauri Beautiful Tears Page (representing the novel: Yelwa Yauri and its future movie) is getting LIKERS from the people of Yelwa Yauri, Nigeria and most likely from other places in Africa.  For more info about this novel, please see articles above or visit its page.  Thanks a lot.

On Yelwa Yauri

--- this could be a stimulus to make this place a memorable spot in the future for tourists...for those where this story becomes a binding force and would necessitate them to commune to this place as a precious token of remembrance...

(taken from one of the details in the Beautiful Tears posts in FB)

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Suggestion ....

  The Microbiology Graduate Program must include Clinical microbiology for an over all perspective of the course and more job opportunities abroad.

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Having two important discoveries in science*   It's time to move on to the other side of the coin--- the arts...  

*Accordingly, "You worked for it. Spent a lot of years on it.  You discovered it! It's really worth those efforts to be internationally and prestigiously awarded!"

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Sustainable Wetlands  (Advanced World Wetlands Day Celebration for this new finding)

  A continous outpouring of clean water from ground below has been discussed currently and an ancient water tank was made a long time ago on its location.[Photos in Facebook were provided]. Some says the tank was established during the time of the Japanese occupation?? The water tank received the water from below ground and has an iron tube or a "spout tube" for its outlet where the stored water can  flow out once a particular level has been reached. In its surroundings are small pools where pushed/implanted iron tubes? are present and clean water will gush out from below... This has been a source of clean water in this community for years... And as what I said in my preface-  "Some have witnessed historical turnovers like the antique reservoirs or tanks". Read my preface here. 

Question: What is the name of this place?

Hint: It is located in a mountain of a town in the Northern province of Iloilo.

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SWS Wetland Members from Bhutan and India-

Memoirs

 I remembered in particular times our in communicado due to severe weather in Bhutan and  am sure there are a wetland activities in your wonderful country of Bhutan..

  I remembered how you (a she) swam the Great Barrier Reef when we were at Cairns.  Wishing you the best of your activities in wetlands of India. You were one of those I nominated for an  Australian Aid and got it. Thanks to Australia.

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Rainfall gauge is now a part of weather forecasting. I talked about it in my article above. Congratzzz.

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New

Google Nest + Reeve Foundation-  helps individuals with paralysis at home.  Search Online..

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Thanks for my featured snippet display (Seach for Savillo) in US Based Google search usually California, New York, Maryland, Texas, Georgia etc. Thanks guys/gals for online searching!

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Viable cocktails

  If living cells are considered as "living organisms"@, why don't make viable cocktails out of  them? Target cells: Immune cells.  Please see my article above on Bacteriophage cocktails. 

**This could help in dengue cure etc. A paper stated that platelets can reproduce while in circulation..

@Please see my article above on this..

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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Temperatures in some places in Europe are scorching high. I wrote a post about this sometimes unexpected phenomenon. Pls. see above. Ty.

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My novel- Yelwa Yauri is copyright registered and Wikisource could not display it.... There is a temporary display about it in Wikisource but it was removed (please see above) for copyright reasons. So be careful of lifting anything about the novel or even a part of  it especially publishing even a part of it. 

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I am grateful for my siblings (U.S., etc.) for supporting my literary  writing interests.... Thanks for the writing gadgets etc...... This will be dedicated to you all.

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I wrote about traveling the easy way above but the act right now of asking locals to pay the continuing trip by performing music on the streets etc., is not what it is all about. I think guesting or consulting or talking with proper invitations having an honorarium will do.

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New Read

  I just read an article that states that the key to happiness is to talk to strangers. That's why I like to communicate with people of different races in one or different place(s).

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Into the Films

 I just searched for Wayne's wherabout online. (He is  Wayne W. Grody, M.D., Ph.D. at UCLA and an advisor of ISMCBBPR, the society I founded). I was surprised that he is also into films.. like the Nutty Professor as a technical advisor (source: IMDB). I am also into this direction science+ art.... Yes.. this would be a great breather..

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First things-

 Lay out the laws of a country you are in when you talk about gender and if  you have other plans. Then reflect toward the meaning of sex (to that one I posted above by a famous sociologist in this area). Avoid fashion statements (as posted above) by constructing new bio related terms  otherwise use "pseudo" and to consult a biologist to avoid confusion in terminologies. 

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Systemic Rooting

A paper from NZ explained that roots from living trees could help sustain life to a stump that I believe has viable roots. It is said that the mycorrhizae are responsible for this sustainable interconnectivity. Last time I read a paper that in particular trees the corona are inhibited from overlapping  so to give the trees their space naturally. 

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CCR5 membrane receptor "plug" could be the same with those without the receptor.. Let the molecular mechanism work for a specific cellular membrane receptor "plugging". Wishing the best!

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Non membranous trancription factors condensate

  Findings from MIT and Whitehead Institute describe how the TF organizes itself and weakly attached to a gene and subsequenty dictates gene expression to a neighborinng gene strip. This may have a therapeutic value  (e.g.  cancer) so as to stop their expression by specific destructive interaction to a TF condensate or the site  of attachment. ... which is which or maybe through other mechanisms.  Just like with my other posts above.. it is sometimes the problems of specificity and plasticity that are existing in laboratory benches..

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When I was at the University of Bayreuth, a colleague showed to me her collections of lichens from the desert of Namibia. Now here is something interesting in this desert an infinite tuning of a song by TOTO titled Africa powered by solar energy. The rains in Africa are the best. There is a portion about that in my novel - Yelwa Yauri. There is a 2019 rendition of this song.

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Remembering Pali Look Out at Oahu, Hawaii. The windward cliff was where my limousine driver took me and that made me experience the very strong winds that could press tightly on me. Am just wondering what are the flora and fauna in this habitat? And how often these crazy winds exist?  Search fyi:  winds pali look out youtube

At Pali Look Out 

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Isolated places on earth makes one think curiously how they adapt in the long run and able to stay and create generations or whatever types of adaptations or actions they do to keep them going in their daily activities and sometimes even people who live in places with modern amenities may share what some of these isolated places lack like internet accessibility. Early and late in the afternoon and early evening internet accessibilities are not available even when there is internet connection. 

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 @ age 18

Biographical Travel @ age 18... how the "Yelwa- Yauri" novel came to be, a photo (other with-relative photos has been posted in About my Photo below. Please click the Photo Link) of my Caucasian relatives with me in Michigan (my late uncle came to the USA most likely during the time of the existence of the Ellis Island Immigration Processing Station) and photos in other states and countries. I think this helps in the making of the person.  Beth,  President of the Society of Wetland Scientists Org USA and a wetland colleague had a very nice TEDx delivery and great travels as part of her career. She  talked about her childhood too but here is mine in photos. 

About my Photos:

My first arrival in the USA via O'Hare, Chicago from London, U.K.  at the age of 18.  This was also my first world tour from Phil. to .........Italy.....Nigeria....Italy,... England, U.S.A.... (a number of states)... Guam.. Mnl... Hongkong-  back to Manila (Specific itinerary well remembered). I traveled alone that's why I am used in traveling alone. The picture showed me and my relatives (Irish- Americans)  at the Grand Rapids Airport, Michigan. I was  leaving for San Francisco, U.S.A. Other photos included in this Photo page were also taken in Michigan with its accompanying details.

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Cold plasma for cancer cure.

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As a Writer

Writing and Reading/Searching gadgets ought to be of different types so as to make oneself entertained and also making the other muscles of the body work not the usual ones. Am I right? Beside the lap tops, cell phones like MOTO and iphone, smaller tablet like Nexus of course I still have one more new...  Thanks.

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Memories

When I was a HS student at the Univ of  San Agustin, there was this univ radio station whose Saturday early morning program opened with this song. Well when I did my travels I usually do it alone.. 😁.     

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Is my statement the first? (with emphasis to behavioral phenotypes)(please see article above on this)

Science Mag of AAAS recently published about genetic markers for same sex 2019  study considered as Giant Analysis (GWAS) by Andrea Ganna and group. In my article above (scroll above to see the article)  I stated that "Some do not have a direct gene equivalent and its expression is due to ACG*".  Though mine does not directly point to their study in same sex behavior it embodies their finding as to my statement. 

*ACG- Associate Collaborative Genes for a Phenotype

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Memory while an elementary student at West Visayas State College Laboratory School was the parade where the Humpty Dumpty sitting in the wall in painted thick molded paper participated. I still can remember how he looks. Well this rhyme is a riddle but what really is the right answer?

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Scientific memory** with the US Department of State, PAEF and our Int'l Molecular Society

**Savillo's proposal was approved by Department of State (Washington, D.C.) and the CIES  resulting to this activity@.  

@Fulbright Senior Specialist (as part of the aforementioned activity) at SEAFDEC.

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Next: Scientific memory at Salt Lake City, Utah

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Blooming mechanisms-

I think more researches are needed for  a) unaltered environmental dormancy or the natural dormancy of  single species of lower forms of organisms such as liverworts**, myxomycetes* (these two I had observed their disappearances after very robust growth- quantity wise)  and b) altered environmental  dormany of single species of the aforementioned or if one could add more single species like that of a  lichen the better. It is high time to look into the environmental factors- both physical and chemical. Or the biotic co- components of the stand where they live.  I think these lower forms are very much sensitive to the environment that operate their reproductive cycles.

*see Philippine myxomycete web page

**see article above on liverworts

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HAZE is like biblical  arrival of smokey death... Haze has reached the central and southern Philippines bringing with it particulates that may not be good for the health + the mainstays of urban/rural pollution... Search Online  (Sept., 2019)  

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Different snippet information about me exist when searched in Google using U.S. IPs (of different states) best in lap top.

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Assignment 2

Biologybrowser (Thomson Reuters) Publications Documentation is displayed in the 2nd New Page

*Please see subpages with Biologybrowser (Internet) Archive Link (url or photos of url) 

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Pertaining to lower forms of organisms- "emotional or suicidal action or resigned to fate (genetic predisposition) for the perpetuation of the species."

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Likers from Africa -

Yelwa Yauri* Beautiful Tears** Page has fans (currently 11 likers/week) from the place/country and in Africa.

*Novel 

**Treatment (with WGA- West)

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Currently, the members of  Yelwa Yauri Beautiful Tears Group (This is a Private/Closed for the Movie- Group) include a  Sophisticated Talented Artist, Photographer, Filmaker, Movie Documentary Specialist from Paris, France;  a Veteran Young Actress from the U.K.;  a  Talented Screenwriter/Actor from the U.K.;  an Extraordinary Creative Artist and Fine Arts Photographer from Italy; a Well Rounded Filmaker/Actor from U.S.A., an Accomplished Publisher, Editor, and Reviewer from the U.S.A. and an Adept Creative Artist from Ivory Coast. 

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you!

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My next novel- Amidst Old Los Angeles portrays a character of Spanish lineage and I wish that there will be likers from Spanish speaking countries or from the South America Continent (just like for my Novel- Yelwa Yauri Beautiful Tears, likers from Africa- see above)  besides Mexico. Embrace the cultures of the world in a friendly way!!

Amigos de habla hispana en América del Sur y México y el resto del mundo, por favor, denle me gusta a esta página: Amidst Old Los Angeles  [En el medio de Old Los Angeles] in Facebook 

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The paper titled "Coping with Climate Change: Fairy Wren Change Breeding Habits" from ANU is interesting to read and that reminds me of one of the statements in 2011 Saving the Wetlands: A Synthesis (Please see link above). 

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I am just extending my warm hello to all my wetland friends in South America especially to my co- organizer from Peru. I am sure how all of you are succeeding in your professional career(s)  and I am so very glad about it!!!.  Keep going... Find the best life ever... pleasant and rewarding. 

Amigos de habla hispana en América del Sur y México y el resto del mundo, por favor, denle me gusta a esta página: Amidst Old Los Angeles  [En el medio de Old Los Angeles] in Facebook 

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Addendum (from above):  10/12/2019~ Bing.com Philippines has a snippet of Isidro A. T. Savillo. Thanks. 

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A compendium of "secrets." (New)

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I need a Life.. (common expression)  and the "trend" of Living

Is minimalism a comfort in life? As to current articles  online, the millineals are now moving toward minimalism. Probably one of the reasons here is what this PhD from Sweden in her dissertation (please see above) wherein she stated in her introduction something about an alternative to an unhealthy matter and it turned out to be unhealthy itself. It is a mask. I think minimalism is a creative ambient way of thinking. It's life in its simplicity whatever is the economic status. I have read how Steve Jobs, Albert Einstein etc. practise Minimalism. Scout for the article and probably find an enlightenment.

Update of what the Millineals are up to: FIRE (find online)

The Dreamers Path... what about it?  11/19/19

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Book Written

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New Dell Page View after updating on Oct. 27, 2019-- Page is from Californa (US IP)

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The U.S. First Responder's Video (in You Tube) is very important. Useful and Highly Educational. Be the First!

*In response to a call for Oct 28 as the National First Responders Day....

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Emotions and Evolution

Emotions are ought to be understood and analyzed....  If it is funneled correctly the better otherwise if it is just a chaff and would never substantiate anything...better not possess it....

I just read an article about emotional marketing...  and the basis of this is how to sell a product through the emotional constituent of the customer... Finding a way of enticing the customer whether this may be a product of different emotional spectra like the emotional spectra of a customer.

Paraphrases of some statements include:  if the customer is sad, it is advisable to sell a product  that threads in sadness like sad music because mournful song replaces the empathetic friend. Or if the customer seems to be enjoying then it is correct to offer items like a self gift (if he/she was praised or received plaudits etc.) or a vacation trip. Expenses may not be an issue here because to be sitting in the beach is the option of importance.  If one is certain about his/her emotions,  thinking about it is no longer an option but when one is uncertain about his/her emotional output there is a need for a complete scrutiny. Regarding the need to be jealous, I was laughing while reading: males need to be jealous for female infidelity because it lowers their capacity for reproduction while females' jealousy toward male infidelity lowers their likelihood of acquiring resources.  It also says that humans feel emotions because of bodily adaptations and social adaptations. Like for instance in small canteens in the US Universities, one need to ask permission to share a table with while in large canteens where clients are medical interns, scientists, etc.,  I think everyone is so tired to deal with this issue for time is precious besides there are so many tables to sit in. It's eating and leaving as quickly as possible.  Likewise in European universities, there is a canteen for professors, scientists, researchers, scholars  and of course, we banded together to go to this place and sometimes we left the place on our own as well as canteen for students, yes, it's big place. Everyone wants a fill and food is sold in an organized and quick way. Getting a whole picture of it, there are rules and proper emotions to deal with. Does culture play a part?  Similar in terms of occupations or degrees or social status or intellectual capacities seems to be the binding factor and where the rules are based. In private restaurants, sharing sometimes is not an option but to wait for an empty table is a must .  I am continously reading about emotions and trying to rationalize it especially that it is very much associated with evolution.

...... At the end (as a whole at that instance), having all those emotional valences in place, what evolutionary hierarchy as a Homo sapiens one could have had reached? Or how Homo sapiens is he or she now?  Is the Homo sapiens starting to evolve into something?

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2019 HIV News..  Interesting for analysis....- 

* This is an interesting find but CTL killing of CDT4 cells (these are important cells of the Immune system) is something to think about... If it is only the target (in/on the CD4 T cell) or the whole cell itself may make a differen ce. Doing this en masse what will happen to the CD4Ts ? Are the CD4Ts even with HIV latency still functioning?  I think the turnover (of the uninfected CD4Ts) has to be considered.  

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Talking about WBC in my above article emphasizes WBC's own protection and I think genetic manipulation of TCRs is much promising at present though allogeneic,  chimeric forms are down in the market..  

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Memoirs - Molekular- Oskar - Dornroschen (Molecule- Oscar- Sleeping Beauty)

In a moment the Breakthrough Prize 2020 will be announced live and  this is labeled as the Oscar of Science. Way back, Our ISMCBBPR's Molecule of the Year 2009, known as the Sleeping Beauty was announced in the media as the Oscar version of the Molecule of the Year.  

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The Physics of kidney stone breaking.  

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Be the relevant master of your scientific profession in the right updated manner!

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Keywords to deal with-

 “CRISPR/Cas9”  resulted to an increasing number of research articles (9332 publications) on PubMed over the years; cytokine release syndrome

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Unraveling  Mendelian Inheritance

What are the Mendelian Crossing Over Procedures  for New Phenotypes? Were the genes of these phenotypes genetically located  and identified (job of Molecular geneticists)? Single gene defect follows Mendelian Inheritance. How about different genes in Mendelian assortment?  Does each behave the single gene defect phenomenon? A summary of  phenotypic Mendelian characteristics and  their corresponding phenotypic genes would be better if reviewed.  Hoping it would not deviate a bit from Mendels Crossing over.

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Messy Scientific Abbrv.. "suffix" tags

... they are 1 (one), I (big letter I) or l (small letter L)

If one is in a rush bearing a recent publication for a lecture... then saw these tags and later would have to stop for a second because... it may not be it...it causes an itch...such interruptions in lectures are stupid bonuses... Terms like CO1/COI in Molecular taxonomy, PDI/PDLI/PDL1... whattt in  Immunotherapy.. I would suggest that this need to be stopped in future scientific literatures.. these are not names of company's molecular kits and they have to be mentioned... use letters (or numbers) that are visibly clear whatever fonts are used in lit... like Q for Glutamine..it's an O with a tail... so clear?

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MD-Ph.D with Caltech

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The "beauty" of working with viruses- when I had to do Phosphorus 32 work in virus identification and PCR as well as membrane autoradiography etc.. way way back.. I am glad to know at present and happy of the job of oncolytic viruses!  

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Are you producing XXXXmabs (ICI) in your country or you are just scrawling reviews forever ??

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Note/Reminder: Marine Bio students  in MolCelBiol lect analysis on Trabectedin; what is its molecular function? How useful? What is the source, where it came from (Carter and Keam 2007)? 

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Coming Up....

Liverworts growth were seen in previous habitat. Please see articles about it  ("Blooming mechanisms" and first article on liverworts above). 

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I am always fond of comparing lower forms with humans like for instance in sexual plasticity; use of growth hormone gene from other sources in fishes and this time Damp (IS) in Cnidaria. The pleasure of having a curious pleasant mind.

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Graduate Students Reminder

-Current Papers are in this area so please Differentiate between Immunotherapy and Gene Therapy and not to mix them in discussions

-A gene that has been bioengineered does not carry the nomenclature of the type of stem cell being used for transplantation; there is no such thing as an allogene/

-A  bioengineered gene will have a protein product that serves a unique purpose or function not necessarily proteins commonly formed by Recom DNA  or alter the normal function of the organism's genetic code such as transgene (germ line existence).  Bioengineering stands by itself as a method of activating cells for therapeutic purposes... like in Immunotherapy. 

- the use of autologous and allogeneic is not only limited to immunotherapy but there are terms such as autologous gene therapy. 

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HSCT and human chimerism.... Is this a product of invasive SC and its pluripotency? just curious...

Keywords: Forensics, host sperm has donor's DNA (HSCT)

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Scientific Testing starts with rats, mice or rabbits...[I was once invited by my US Prof. to generate MABS on rabbits]...  after which Humans who need it.. it's the clinical aspect but currently there is such a thing as self testing.. because of the love for Genetic Engineering.  (Pls. refer to  Leapsmag  online. Jan 2018 article that states "Genetic Engineering is the last frontier of Human Freedom". This is an Opinion Essay). Nevertheless, currently a publication from the University of Alberta that the  DNA  is not your destiny or a good predictor of  your health came out. Instead, the essential  factors mentioned include measuring metabolites, microbes and proteins and not the genes .  In my above posted  articles I wrote about the need of proper/correct and essential Molecular Nutrition/Proteins/Metabolites for our health.

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Live it up WBC! (See this statement in the above article)  I wrote about the potential of the WBC to fight it off and that is true... It could fight and kill even the tumor cells though its life span is short.   I wrote about ways that this could be strengthened by epigenetic as well using post translational processes and so on. (see above). There are hindrances to this capacity of the WBC and that is why there are new ways of getting rid of these barriers:  ICI,  the formation of DAMP and so on. They are focusing on combined therapies so the "exhausted" WBC could be helped. But beware there are cells immunity wise (depending in the conditions and types) sometimes do the opposite that is the problem with their dichotomous roles. But without these hindrances WBC is a fighter! 

** Biological Evolution of Immune Cells - evolution of WBC may entail additional cellular and molecular functions such as CD4Tcell (University College London  2020) from being a helper and regulatory cell to a cytotoxic killer cell. 

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Antibody against allergy

This is a great breakthrough (11/14/2019) and hope it would be of great help in ridding of  immune signalling molecules responsible for any allergen...  Thanks to Etokimab, a major component in this Stanford - led pilot study. 

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Thinking Twice-

Clinical trials- can it cross geographically especially for those who can't afford to buy them later as medicines? Think of the MABs used for ICI they are very expensive.   I know that clinical trials must not only include specific population of people but other peoples in other areas as well so the specificity and sensitivity of these medicines (may come in whatever forms) be determined/assured before they can be considered as "universally" prescribed and government approved medicines. I've read about therapeutic items that could not work in Africa because of cross reactivity with other microbes.. etc. 

*Bioethicist L. Zoloth talked about "Scientists owe clinical trial volunteers support", a Dec. 30, 2019 article by T.H. Saey.

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Writers and Nature/Nature Re-examined

-I spent time reading the biographies of famous poets. They have particular reasons to write and how they devoted themselves in it.  A greater part of their writings is bundled in natural influence.  Yes nature is very much a component of us...Can one just "stand alone" without the natural elements stirring the senses ? In your room, by just listening to the Passer montanus (a common tropical homely bird in the Philippines) is enough to satiate your day. They communicate, skip in speed in window ledges and make sounds of their picking bills when they have to catch an insect- food... After the bombastic sounds of New Year celebration, their presence the next day is nil or rare. But for sure, they will then be back to congregate. Unlike, alleged reports that some birds in other countries die due to hoarse surprising "sounds", they fairly surpass this as a form of stress.

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I've read that 2019 is considered as the Year for Gene therapy and to welcome it's important molecular constituent the CRISPR (formally known as the CRISPR-Cas9)

In my previous article above, I wrote about the numerous publications involving CRISPR but I really donot have much time to make a thorough review of it. [But I will soon: Wang et al, 2019 downloaded] I think those articles involve animal trials. But this time, CRISPR is now entering the clinical trial arena.  I hope this will spark success. I am just recalling reviews regarding the clinical trials of Immunotherapy.

What is CRISPR- Cas 9? (definition taken from Discovermagazine dated January 1, 2020)- (clustered regularly interspaced short palindromic repeats) therefore a genetic code consisting of an RNA strand and this comes with an enzyme known as Cas9, that functions like a molecular scissor that can cut and remove specific genes.  By doing so, the removal of a "defective" gene is viable and subsequently a  gene which is functional could now take its place. 

*Marsa, Linda. 2020. Gene Therapies make it to Clinical trial. Discovermagazine. com Succeeding article: Gene therapy without CRISPR. In print: Gene therapy gets clinical

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ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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Mitotic Relevance

 When it comes to Gene therapy*, only a portion of cells experimented or utilized can avail of this procedure and the main bulk of cells cannot be corrected unless if I miss it there is some technique that could do as much as gene splicing of the target defective genes in tissues**. While in Immunotherapy, the target is quite contained unless as in the case of cancer, the tumor cells have not spread. Once the expression of defective genes exists plus expression of those cells which carry the normal genes after genetic transplantation, what would be the resulting effect? 

*on CRISPR Cas9

** I encountered a term and this include "systemic" I think in terms of trial application. 

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On Cancer and UK's proposed Complex Innovative Design (CID) Trials- This is to overhaul the usual common clinical trials where in it will include  multiple issues regarding the new drugs to be tested and  more involvement of patients*.  *Extensive clinical trials of individuals living in different  geographical areas which I said in my above article could be of help and of course scientific  participation of volunteers in each trial involving specific needs (e.g. kind of cancer) so as to rule out or zero in to the  trial being  undertaken.  The goal here is to reduce the time of approval of new treatments so they could be made available to patients in a faster manner.

*New cancer drugs could be made available faster following clinical trial reform by Shaun Lintern. Published in Independent.co.uk. January 06, 2020.

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In my above article, I examined a publication regarding "exposing HIV hiding in CD4T cells". Kick and Kill approach is being rendered here. It involves engineered cells that are able to “kick” HIV out of hiding and also activate the expansion of HIV-specific CD8+ T cells (CTL) capable of killing the exposed HIV. The researchers are pursuing funding for clinical trials to test MDc1 in humans with the goal of "HIV cure." Here is  quite a similar paper which deals in "smoking out HIV dormancy" in CD4T cells.

A 2020 Norwegian University paper talked about "smoking out" HIV dormancy in  CD4T cells. Accordingly, there are possibilities about HIV not capable of infecting the CD4T because there is a mechanism that involves a lock- key grip, e.g. ligand interaction  (probably another way besides CCR5 ?? for CCR5 is not mentioned). Therefore the HIV can get trapped in the endosome of the uninfected CD4T  and HIV is destroyed producing HIV fragments  that will activate the TLR8, a component of an innate system that is found on the T cell, the latter being a part of adaptive immunity. Subsequently, the cytokines produced after TLR8 received the stimulus  will influence the replication of the dormant HIV in the uninfected cell likewise in infected cells. Thus, the dormant HIV is activated. But I am just wondering when there are numerous replicates/virions of the HIV as a result of the activation of uninfected T cell with the endosomal HIV and the infected T cells, then what happens next?  What will eliminate them in the field? 

It is expected that there will be vigorous killing  as well as the paper says "curing HIV" but I hope that the elimination process will thoroughly be a success.   

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Trained Immunity (TI) (M.G. Netea) is defined as the ability of the innate immune system to possess the immune memory and this involve the epigenetic programming* of myeloid lineage cells  (WBC- macrophage (monocytes), etc.) that will result in changes in their metabolic and phenotypical behavior resulting to a stronger immune response to  a secondary stimuli. 

In my above articles in fact, one of my earliest titled: Epigenetics* Theory  on WBC. I stated these statements  referring to strengthening the WBC:    

 " It could be a post translational scheme of the epigenetic* factors (like the histone). Or it could be done during the translational processes. It could be a participatory of an external/neighboring gene and/or a non- genetic factor (in the environment)". 

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Solid Tumors and Other Clinical Trials

Alpha Tau Medical is currently conducting and initiating clinical trials for Alpha DaRT treatment in Canada, France, Israel, Japan and Russia. In my previous articles above I vouched for a geographically wide spread clinical trials.

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Good news for the medicines to attain their favorable/regulated prices including cancer med. Also a certain bank has an ATM for SC... that's good too.  But I do not see Public Transport (PT) to have seats for SC. In the US there is a seat parallel to the body of the PT vehicle in front for SC/Disabled (well their PT are quite advanced- accommodate wheelchair -bound passengers) as well as a PT (solely?) for SC in California whose destination is a race track. This is not free.

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In my above articles I wrote about the storm paths  in the Visayas region. Was it the year 2018 that there was no powerful storm during Nov./Dec.? But 2019 was not spared. I had compared this to the hurricane paths in Southern USA. Louisiana is a very nice place minus the flood with her parishes and wetlands. But they (with Texas etc.) have their own way of bolstering their homes from the storm. I was able to read how the Vietnamese construct their storm proof house especially that they live in  storm paths. This was a project of UNDP and other philanthropic organizations and the specification for house structure and construction must follow the  UNDP guidelines. There are braces on the roof, two storey house with upper floor wide window as escape route etc. Read more on this online.

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Keywords to look into: Anti CRISPR proteins, CAS 9 disruption of function, microRNA (revival)

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*^Tertiary lymphoid structures (TLS) inside some tumors- are full of B cells and are dubbed as "learning centers" for these cells to be educated so as to effectively learn to recognize and attack cancer cells. ...... These 3 studies show exciting data demonstrating that B cells which make antibodies significantly influence the responsiveness of patients with  certain cancers to immunotherapy.

*Scientists find immune cells that fight tumours from within- article from Bangkok.post 16th of Jan., 2020

In my article above- I posted an earlier statement  about "antibodies against cancer" ... here is a portion of it... "I have read antibodies directed towards op (oncogenetic proteins) .... but i think it was just for characterization...   Antigens for op need to be conserved..... and probably it could be lysed later by  something which eventually works like a vaccine. It's high time to think about it." or the B cells in the TLS  (Tertiary lymphoid structures^) can assume a different role and this belongs to the category- Introduction of the Biological Evolution of Immune cells (pls. see Discoveries sub page ) or both are possible. 

One of the possibilities  here  is the natural equivalent of the "man's guided"  MABs production toward the ICI where the T cells could have access to tumor cells where then it can  kill the latter. But the question here is... Does the antibodies produced be able to reach as far as the ICI considering the B cells location within the tumor?  How about the processing of antibodies?

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Fans/Likers from Africa

 Currently there are 130 likers mostly from Africa  for the Yelwa Yauri Beautiful Tears Page. Thanks!  

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USC school of Med has a Keck Farmers Market every Tuesday. Having a nice clean produce one can do the cooking in such a way that all in all is environmentally healthy. 

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Zoonoses and a veterinary clean up

~I am just wondering what happened to the zoonotic society based in Europe where I was a member. Agricultural wise or even involving domestic pets, these need to be free from various pathogenic organisms...they could be carriers or the disease causing ones. They could be animals in large scale or small scale  but for pets one is much better than two. Trained to be solely within the premises not to be out in the road or commune with other stray dogs. Also to have a look out for wild animals like bats or strange/new birds in the vicinity. And for travelers or for those who were out of the country for a long time, one can be a reservoir of the other types of new pathogens even new forms of allergenic reactions (The latter statement  may not be purely zoonotic) or one goes forest hopping especially if it is rich in carriers for transmission. And of course these herded animals ought to have nutritious foods to fight off diseases. In fact they can even take care of themselves just like the wild Virginian opposum. In this manner, at the very start, zoonotic transmission of viruses etc, can be alleviated. As cliche as this statement is but ought to be repeated:  Once they favorably transfer to humans as their new host, as new pathogens the bodies still have to produce the necessary  defensive cells to get rid of them. This takes time or sometimes time is quite long for the making of desirable antibodies/cells and the result is catastrophic.  Ebola is one example. 

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Cardiff University Study Jan. 20, 2020. BBC News: 

A  T cell has been claimed to treat all cancers (lung, skin, blood, colon,  breast,  prostate, ovarian, kidney and cervical cancer) if harnessed. It has a receptor that interacts with a molecule called MR1 that is present on the surface of every cell. MR1 is thought to give a signal to the immune system regarding the peculiar metabolic activities of tumor cells. Therefore This T cell can find this MR1 and in process subsequently kill these cancerous cells in the lab. 

As the President of ISMCBBPR and one of the Voters for the Molecule of the year, I am very much doing in depth analyses of the publications/news item of  recent findings. Which of the findings are near reality? There are always promises but we (as Voters) want something  in a split of a second something that is successful (in treating diseases such as cancer) realistically.

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February 2, 2020

Happy Wetlands Day around the World!!

Thou I celebrated World Wetlands Day 2020 ahead. Please see article above on "sustainable wetlands".

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Anniversary date for the D.Biol.Sc.h.c. ... Before 2005?  

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Acidic Oceans?

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International Health is one of the exciting fields to specialize in Public Health let us say at JHU. But the horror may exists once the individual is in the field. The zoonotic bug is there:  how not to be infected?; how to contain it?: how to stop the spread? (esp. if airborne and to eliminate the in between agents; how not to bring the bug to the population that were not infected ); how to identify the quarantine areas and its needs?; how to implement the extreme procedure of  disease containment for certainty purposes?; how to prepare the emergency medicines for zoonotic  esp. viral infections for future use?; how to effectively deliver the medicines/services  considering the safety of the deliverer/transporter?; how to designate/prepare a portion of the hospital/PH research institution, etc.  as extremely infectious area for new zoonotic diseases?; how to put up infectious health centers for this purpose especially in nearby areas of the epidemic?  There are some progress in the logistics and that's better.  

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Sabah, Borneo

I just saw that photo of the orangutan extending his/her hand to help the warden half submerged in the river clearing of it with snakes that prey on these monkeys- a part of their conservation project. If these animals could just understand how they are being helped and help themselves and their helper this could be new to science. I also like the warden refusing the extended orangutan hand because who knows what will happen next! Good quick thinking.

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ISMCBBPR Molecule of the Year Rigid Criteria

  The MOY of ISMCBBPR are all promising and utilizable molecules for research and for therapeutic purposes and most as far as I remember are basic. But our next batch of nominees will be based strictly in the results of animal and clinical trials in replicates. We want to award molecules that are about to be utilized for the human/organisms need that with only a little refinement of the Molecule or its target there is a certainty of success (in replicates). A lot of Molecules with different titles are sprouting out and we want to be different. I have been reading a lot of publications in oncogenic animal and clinical trials. Thanks to my  US sib (JHU,Oxford)

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New Snippet : Discoverer

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Pigeon Birds Go Urban

*A similar situation I had seen in a Singapore article.

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Molecular Synchronization

Time I think has a general rule in modifying some DNA expression that could be universal in some species like for instance in terms of infection it could either remain dormant rather than infectious or will exhibit infectious gene disintegration or strain conversion exhibiting pathogenicity of some sort. This could be applicable to all of the same species or strain that have existed within the similar kind of  organism as its host. In higher organisms this could be observed as "natural" death of flock/group of the same species in a particular time as one but its applicability is much reduced the higher the complexity of the organism. 

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2019 

Cited in a Brazilian Paper titled:  A mixobiota de manguezais e a ocupação de microhabitates* from the book titled

"Conhecimento, consevação e uso de FUNGOS" by Editora do Instituto Nacional de Pesquisas da Amazônia.*

*Copies available in ResearchGate and in Google Scholar

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As expected any probe that is used to identify a virus, etc. must be specific and sensitive*. The former means that it is not going to cross react with any other genetic material. For the new coronavirus, there was a speedy development of an assay that is used currently around the world.

Besides, probes and primers for the virus are now available for vaccine development. 

Yesterday, I just knew that the official name of the virus is SARS CoV 2. I'd rather not use SARS in naming it. SARS as to my knowledge is an excellent virus in reconfiguration**. But this CoV 2 is not as super as the previous sars and only share quite a percentage of its genome as published. SARS reconfiguration is as frightening as far as  I can remember. But if this is as excellent in reconfiguration as the previous sars let it be then.

*probe used, specimen utilized: b.lavage, etc.

**as an obligate parasite, its ability to reconfigure^ itself from its component parts once outside the host to become a living thing once it comes in contact with a source of a living cell.

^how quick and the number of days outside of the living cell it can reconfigure into a living thing.

ATTENTION: All information contained herein must not be cited, photocopied, printed, distributed or discussed publicly or privately without the consent of the author: Isidro A.T. Savillo. Thank you! THIS IS NOT FOR PROMOTIONAL PURPOSES BY or FOR ANY PARTY!

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