Digital and Confocal Microscopy

The advanced confocal microscopy center of the LTTA laboratory is dedicated to innovation in cellular imaging technology, providing a highly competitive service through the use of technical expertise and innovative, sophisticated imaging instrumentation. Its range of applications extends from basic biomedical research to more specialized services, such as screening analysis of molecular activities of interest in the pharmaceutical field.

The remarkable technological progress made recently in investigative instruments and image analysis has enabled the achievement of high resolution and contrast even from complex samples, opening important new perspectives in biological experimentation. At the same time, the development of specific, synthetic, and engineered probes to label and dynamically track cellular structures or physiological parameters has allowed researchers to accurately distinguish various subcellular structures in a single experiment.

The goal of the advanced microscopy center is to serve as a reference point by providing access to state-of-the-art instrumentation, image acquisition methods, and highly competitive analytical technologies. Live imaging has become an indispensable tool in many research laboratories and a fundamental methodology in various medical disciplines, enabling the study of cellular architecture and the real-time analysis of dynamic molecular processes in living cells, thereby enhancing the understanding of cellular and tissue functions. Additionally, it allows for high-throughput assays in biological processes, extending its applicability and interest to pharmaceutical companies.

The technology available in our laboratory—supported by decades of experience in microscopy, the availability of recombinant probes, and expertise in developing optimal protocols—thus enables us to meet the needs of the scientific community and offers a functional screening method to track dynamic changes over time in hundreds of thousands of living cells.