Biobank

The research team managing Biobank service has a strong and solid background and recognized achievements in biomedical research. Their expertise spans a wide range of disciplines, including cell and molecular biology, vascular pathophysiology, stem cell research, and onco-hematology, as evidenced by numerous publications in leading international scientific journals. The Biobank actively supports the design of preclinical studies, aiming to evaluate the effects of drugs or bioactive molecules on key cellular parameters such as apoptosis, cell cycle progression, cytokine release, and the expression of specific surface markers.

Thanks to the advanced technologies available, Biobank is able to isolate, purify, expand, and characterize human primary cells obtained from various tissues (including peripheral blood, bone marrow, umbilical cord, and Wharton’s Jelly) collected from both healthy donors and patients. The isolated cells can be cryopreserved in nitrogen vapor for long-term storage (up to 10 years) while maintaining their viability. A computerized management system ensures security, full traceability, and donor anonymity, assigning each sample a unique barcode identifier.

The associated database allows for easy retrieval of samples with specific characteristics, thereby facilitating the launch of new targeted studies. In addition to cells, the Biobank also stores biological fluids such as sera and plasma, and performs cell-based assays to analyze parameters such as cytotoxicity or cellular responses to specific stress conditions.

Furthermore, Biobank is equipped with innovative technologies that enable:

• Multiplex analysis of soluble molecules in samples like serum, plasma or cell culture supernatants;

• Real-time analysis of cell viability, adhesion, and proliferation;

• 3D cell cultures development under controlled conditions, generating more physiologically relevant models for oncological and pharmacological research.