I recently gave a friend reishi - and her blood pressure dropped 20 points overnight. We were both shocked... then i find that nf-kappa b looks to be causing inflammation... so that is why reishi worked!
Hypotensive Effects and Angiotensin-Converting Enzyme Inhibitory Peptides of Reishi (Ganoderma lingzhi) Auto-Digested Extract
http://www.mdpi.com/1420-3049/19/9/13473/htm
Inflaming Hypothalamic Neurons Raises Blood Pressure
http://www.sciencedirect.com/science/article/pii/S1550413111002245
Inflammatory cause of metabolic syndrome via brain stress and NF-κB
http://www.impactaging.com/papers/v4/n2/full/100431.html
The sympathetic control of blood pressure
http://www.nature.com/nrn/journal/v7/n5/full/nrn1902.html
Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB
http://www.nature.com/nm/journal/v17/n7/full/nm.2372.html
Newfound Brain Cells Linked to High Blood Pressure
http://www.livescience.com/26266-new-brain-cell-blood-pressure.html
Inflaming Hypothalamic Neurons
Raises Blood Pressure
Prevalence of resistant hypertension in the United States, 2003-2008.
http://www.ncbi.nlm.nih.gov/pubmed/21502568
Common virus could cause high blood pressure
http://news.harvard.edu/gazette/story/2009/05/common-virus-could-cause-high-blood-pressure/