Ta-Chun Chien (簡大鈞)

I, graduated from National Taiwan University, was trained in transgenic mice technology. Since my academic pursuit is to disclose the function of neuronal circuitry, electrophysiology became apparently indispensable to my study. I am currently interested in the role of ASIC1a in fear memory. With my expertise in mouse genetics and the cutting-edge electrophysiology techniques, I wish to unravel how ASIC1a affects the gating of inhibitory circuitry, especially in the amygdala.

Education

B.S.    National Taiwan University

M.S.    National Taiwan University

PhD student  2010~

Taiwan International Graduate Program, Academia Sinica

Publications

Chiang PH, Chien TC, Chen CC, Yanagawa Y, Lien CC. ASIC-dependent LTP at multiple glutamatergic synapses in amygdala network is required for fear memory. Sci Rep. 2015 May 19; 5:10143. [PDF] [Supporting information] [PubMed]

Wu PY, Huang YY, Chen CC, Hsu TT, Lin YC, Weng JY, Chien TC, Cheng IH, Lien CC. Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory. J Neurosci 2013 Jan 30; 33 (5): 1828-32. [PDF] [PubMed]

Chiang PH*, Wu PY*, Kuo TW*, Liu YC, Chan CF, Chien TC, Cheng JK, Huang YY, Chiu CD, Lien CC. GABA is Depolarizing in Hippocampal Dentate Granule Cells of the Adolescent and Adult Rats. J Neurosci 2012 Jan 4; 32 (1): 62-67. *Co-First author [PDF] [PubMed]

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