Yen-Chu Lin (林晏竹)

I started to learn neuroscience and experimental techniques of electrophysiology in Lien Lab in 2007 and got the master degree in neuroscience in 2010. My past work focused on the functional expression of acid-sensing ion channels (ASICs) among different cell types in the rat hippocampus, which was studied with electrophysiological and molecular approaches. Now we are trying to reveal their functional role in the central nervous system by combing the genetic manipulation of ASICs. As a research assistant now, I also help investigate the pharmacological effects of an anti-epileptic drug, lamotrigine, under the pathological condition. I also expect to have a far broader learning in neuroscience research field.

Education

B.S.    National Sun Yat-sen University

M.S.    National Yang-Ming University (2007-2010)

Master of Science

Institute of Neuroscience, School of Life Sciences

Current position

Junior Specialist at UC Davis Medical center

Publications

鈣離子通透性酸偵測離子孔道在大鼠海馬迴NG2神經膠質細胞高密度之表現 (碩士論文)

High-Density Expression of Calcium-Permeable ASIC1a Channels in NG2 Glia of Rat Hippocampus (Master thesis)

Huang YY, Liu YC, Lee CT, Lin YC, Wang ML, Yang YP, Chang KY, Chiou SH. Revisiting the Lamotrigine-Mediated Effect on Hippocampal GABAergic Transmission. Int J Mol Sci 2016 Jul 22; 17 (7). E1191. [PDF] [PubMed]

Chan CF*, Kuo TW*, Weng JY*, Lin YC*, Chen TY*, Cheng JK, Lien CC. Ba2+- and bupivacaine-sensitive background K+ conductances mediate rapid EPSP attenuation in oligodendrocyte precursor cells. J Physiol (London) 2013 Oct 1; 591(19): 4843-58. *Co-First author [PDF] [PubMed]

Wu PY, Huang YY, Chen CC, Hsu TT, Lin YC, Weng JY, Chien TC, Cheng IH, Lien CC. Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory. J Neurosci 2013 Jan 30; 33 (5): 1828-32. [PDF] [PubMed]

Lin YC, Liu YC, Huang YY, Lien CC. High-Density Expression of Ca2+-Permeable ASIC1a Channels in NG2 Glia of Rat Hippocampus. PLoS ONE 2010 Sep 10; 5 (9): e12665-e12672. [PDF] [PubMed]

Weng JY, Lin YC, Lien CC. Cell Type-Specific Expression of Acid-Sensing Ion Channels in Hippocampal Interneurons. J Neurosci 2010 May 12; 30 (19): 6548-58. [PDF] [Supplemental Data] [PubMed]

Contact information