4. The cell membrane

4.1 Fluid mosaic membranes

The structure of cell surface membranes allows movement of substances between cells and their surroundings and allows cells to communicate with each other by cell signalling .

a) describe and explain the fluid mosaic model of membrane structure, including an outline of the roles of phospholipids, cholesterol, glycolipids, proteins and glycoproteins

b) outline the roles of cell surface membranes including references to carrier proteins, channel proteins, cell surface receptors and cell surface antigens

c) outline the process of cell signalling involving the release of chemicals that combine with cell surface receptors on target cells, leading to specific responses


The phospholipid bilayer

Structure and function of the bilayer

Fluid mosaic model and protein functions

Cell signalling

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4.2 Movement of substances into and out of cells

The fluid mosaic model allows an understanding of how substances enter and exit cells by a variety of different mechanisms. Investigating the effect of increasing the size of model cells allows an understanding of the constraints of obtaining resources across the cell surface and moving substances out of cells.

a) describe and explain the processes of diffusion, facilitated diffusion, osmosis, active transport, endocytosis and exocytosis (no calculations involving water potential will be set)

b) investigate diffusion and osmosis using plant tissue and nonliving materials, such as Visking tubing and agar

c) calculate surface areas and volumes of simple shapes (including cubes) to illustrate the principle that surface area to volume ratios decrease with increasing size

d) investigate the effect of changing surface area to volume ratio on diffusion using agar blocks of different sizes

e) investigate the effects of immersing plant tissues in solutions of different water potentials, using the results to estimate the water potential of the tissues

f) explain the movement of water between cells and solutions with different water potentials and explain the different effects on plant and animal cells

Diffusion

Surface area to volume ratio

Osmosis

Active transport

Membranes and transport study club

Investigating osmosis