Nicholas Santiago

Predicting Alzheimer’s Disease

Nicholas Santiago

My research is focused on neurodegenerative disease, more specifically Alzheimer’s Disease. Alzheimer’s Disease is a progressive disease that slowly destroys one's memory and cognitive abilities. One study that I found was about creating predictive models for the disease and improving them by exploring more genetic risk factors that could potentially lead to Alzheimer’s. A second study that I encountered was about analyzing gene panels which could be linked to pathogenic or causative variants. They would be able to identify mutations in those with early-onset Alzheimer’s. The last study that I read was about researchers who predicted Alzheimer’s disease based on blood gene expressions using three public data sets. Researching Alzheimer's disease prediction is very crucial for today’s world, as there is no current cure for the disease. Therefore, predicting if someone has Alzheimer’s early in life versus later is much better for receiving treatment and being able to plan ahead. I will pursue Ingenuity’s Research Practicum and hope to continue researching Alzheimer’s Disease with a researcher from Johns Hopkins University.


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