The key to the estimation of the disassociation energy is a database of radicals with associated dissociation energies. The dissociation energy of the target radical is estimated by finding a the largest (defined by the number of atoms in the structure) radical structure in this database that is a substructure. The database is based on the article of Luo[49] and consists of 109 radical species: 10 alkyl radicals up to 4 carbons, 23 alkene and alkyne radicals, 35 alkyl radicals with oxygen, 2 containing sulfer, 12 alkyl radicals containing nitrogen, 23 alkyl radicals containing halogens and 4 alkyl radicals containing silicon.