Stimulates alpha-1, alpha-2, and beta-1 receptors
Onset: very rapid
Half-Life: 2.5 minutes
Concentration: 4 mg/ 250 mL NS/D5W **
8 mg/ 250 mL (Central Line)
16 mg/ 250 mL (Central Line)
Starting Dose Range: 0.03 mcg/kg/min
Titration Dose Increment: 0.02 - 0.05 mcg/kg/min
Rate of Titration: 5 minutes
Maximum Dose: 1 mcg/kg/min
Maximum Peripheral Dose: 0.3 mcg/kg/min
Central/Peripheral: (See concentration above)
** may be administered peripherally if only ONE vasopressor and if infusion < 12 hours
Adverse Effects
Tachyarrythmias
Tissue NecrosisÂ
Ischemia