Stimulates mostly beta-receptors, with very little stimulation of alpha-receptors
Used for cardiogenic shock
Renally excreted
Onset: 1-2 minutes
Half Life: 2 minutes
NOTE: Prolonged infusion of DoBUTamine may cause desensitization of beta-receptors and reduced efficacy, making it easier to wean
Concentration: 250 mg/ 250 mL NS/D5W
500 mg/ 250 mL
Starting Dose Range: 2.5 mcg/kg/min
Titration Dose Increment: not titrated by RN; MD to order fixed dose
Rate of Titration: 5 minutes
Maximum Dose: 20 mcg/kg/min
Maximum Peripheral Dose: n/a
Central/ Peripheral: Central line preferred (for both concentrations)
Note:
Can cause hypotension in the presence of hypovolemia
Contraindicated if sulphite allergy
Doses up to 40 mcg/kg/min can be used, but is not common