Week 2: Background topics

Lecture 3: The healthcare industry

Topics/Videos

• Participants

• Medical Education & the Economics of Medicine in the US

Slides

• pdf

Required Reading

• None

Lecture 4: Evidence Based Medicine

Topics/Videos

• A brief history of medicine

• Evidence based medicine

  • Example: “Effect of Renin-Angiotensin-Aldosterone System Inhibitors in Patients with COVID-19: a Systematic Review and Meta-analysis of 28,872 Patients”, Baral et al Curr. Atherosclerosis Reports (2020) 22:61

Slides

• pdf

Required Reading

• “Effect of Renin-Angiotensin-Aldosterone System Inhibitors in Patients with COVID-19: a Systematic Review and Meta-analysis of 28,872 Patients”, Baral et al Curr. Atherosclerosis Reports (2020) 22:61

Optional Reading

• The Flexner Report

  • See also The State of Diversity in the Health Professions a Century After Flexner

• Evidence-based practice for individuals or groups: let’s make a difference, de Groot et al Perspect Med Educ (2013) 2:216–221

• Osteoporosis therapy: an example of putting evidence-basedmedicine into clinical practice, Hosking, Geusens, Rizzoli; QJM 98(6), pp. 403–413,

• "Why Most Published Research Findings Are False", Ioannidis, 2005, DOI: 10.1371/journal.pmed.0020124

• "Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials" , Anglemyer, et al Cochrane Database Syst Rev. 2014,Lancet. 2011 Nov 19;378(9805):1812-23. doi: 10.1016/S0140-6736(11)61539-0.

• "Clinical Versus Mechanical Prediction: A Meta Analysis" Grove et al Psychological Assessment, 2000 12(1) 19-30

• A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19, Boulware, et al. N Engl J Med. 2020 doi: 10.1056/NEJMoa2016638