1. Mohandass A, Surenkhuu B, Covington K, Baskaran P, Lehmann T, Thyagarajan B. Kainic Acid Activates TRPV1 via a Phospholipase C/PIP2-Dependent Mechanism in Vitro. ACS Chem Neurosci. 2020 Oct 7;11(19):2999-3007. PubMed PMID: 32833423.

  2. Mohandass A, Krishnan V, Gribkova ED, Asuthkar S, Baskaran P, Nersesyan Y, Hussain Z, Wise LM, George RE, Stokes N, Alexander BM, Cohen AM, Pavlov EV, Llano DA, Zhu MX, Thyagarajan B, Zakharian E. TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors. FASEB J. 2020 Aug;34(8):10887-10906. PubMed PMID: 32609392; PubMed Central PMCID: PMC7496617.

  3. Baskaran, P, L Markert, J Bennis, L Zimmerman, JH Fox, and B Thyagarajan. Assessment of Pharmacology, Safty,and Metabolic aActivity of Capsaicin Feedig in Mice. Scientific Reprts. 2019 9:8588.

  4. Baskaran, P, K Covington, J Bennis, A Mohandass, T E Lehmann and B Thyagarajan. Binding Efficacy and Thermogenic Efficiency of Pungent and Nonpungent Analogs of Capsaicin. Molecules 2018, 23 (12), 3199.

  5. Krishnan, V, Baskaran, P and B Thyagarajan. Troglitazone activates TRPV1 and causes deacetylation of PPAR gamma in 3T3-L1 cells. Biochimica et Biophysica Acta - Molecular Basis of Disease, Nov 2018. Accepted.

  6. Agarwal, S, J Fox, B Thyagarajan and JH Fox. Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochodnrial dysfunction and can be remlved pharmacologically. Free Radic Biol Med 2018 May 20; 120:317-329.

  7. Baskaran, P and B Thyagarajan. Measurement of Basal and Forskolin-Stimulated Lipolysis in Inguinal Adipose Fat Pads. J. Vis. Exp. 2017 Jul 21; 125

  8. Thyagarajan, B, JG Potian, JJ McArdle and P Baskaran. Perturbation to Cholesterol at the Neuromuscular Junction Confers Botulinum Neurotoxin A Sensitivity to Neonatal Mice. Toxicol. Sci. June 22, 2017 Doi:10.1093/toxsci/kfx127.

  9. Baskaran, M, P Baskaran, A Navamoney and B Thyagarajan. Preparation and Evaluation of PLGA-Coated Capsaicin Magnetic Nanoparticles. Pharm Res. 2017 Jun; 34(6):1255-1263.

  10. Baskaran, P, V Krishnan, K Fettel, G Pang, Z Zhu, J Ren and B Thyagarajan. TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue. Int. J. Obes. Feb. 2017 p 1-11.

  11. Baskaran, P, V Krishnan, J Ren and B Thyagarajan. Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms. Brit. J.Pharmacol. May 2016 DOI: 10.1111/bph.13514

  12. Asuthkar S, Demirkhanyan L, Sun X, Elustondo P, KrishnanV, Baskaran P, Velpula KK, Thyagarajan B, Pavlov E, ZakharianE. The TRPM8 Protein is a Testosterone Receptor. Part II: Functional Evidence for an Ionotropic Effect of Testosterone on TRPM8.J Biol Chem. 2014 Dec 5. pii: jbc.M114.610873.

  13. Asuthkar S, Elustondo PA, Demirkhanyan L, SunX, Baskaran P, Velpula KK, Thyagarajan B, Pavlov E, ZakharianE. The TRPM8 Protein is a Testosterone Receptor. Part I: Biochemical Evidence for Direct TRPM8-Testosterone Interactions. J Biol Chem. 2014 Dec 5. pii: jbc.M114.610824.

  14. Thyagarajan, B, JG Potian, P Baskaran andJJ McArdle. Capsaicin modulates acetylcholine release at myoneuroal junction. Eur. J. Pharmacol. 2014Dec 5;744:211-9. doi: 10.1016/j.ejphar.2014.09.044. Epub 2014 Oct 23.

  15. Padmamalini Baskaran and Baskaran Thyagarajan. Acute and chronic effects of botulinum neurotoxin A in mammalian neuromuscular junction. Muscle and Nerve. 2013 Nov 12. PMID: 24162247

  16. Baskaran, P, TE Lehmann, E Topchiy, NThirunavukkarasu, S Deshpande, BR Singh and B Thyagarajan. Effects of EnzymaticallyInactive Recombinant Botulinum Neurotoxin Type A at the Mouse NeuromuscularJunctions. Toxicon 2013 Jun 25. pii: S0041-0101(13) 00228-6. PMID:23810945

  17. Garcia CC, JG Potian, K Högnason, B Thyagarajan, L. G. Sultatos, VH Routh, and JJ McArdle. Acetylcholinesterase downregulation contributes to neuromuscular junction dysfunction in experimental type I diabetic neuropathy. Am. J. Physiol. 2012. PMID: 22739110. PMID: 21051321

  18. Ho, M, LHChang, M Pires-Alves, B Thyagarajan, JE Bloom, Z Gu, KK Aberle, SATeymorian, Y Bannai, JJ McArdle and BA Wilson. RecombinantBotulinum Neurotoxin A Heavy Chain-based Delivery Vehicles for Neuronal CellTargeting. Protein Eng Des Sel. 2011 Mar;24(3):247-53. PMID:21051321

  19. Potian JG, Vishwendra Patel, JJ McArdle and B Thyagarajan. The inveterate botulinum neurotoxin A ushers in exoendocytic crypts. The Botulinum J. 2010. 1(4). 418-430.

  20. Potian, JG, B Thyagarajan, K Hognason, F Lebeda, JJ Schmidt and JJ McArdle. Investigation of “CRATKML” derived peptides against botulinum neurotoxin A poisoning in vivo and in vitro. The Botulinum J. 2010. 1(4). 407-41

  21. Thyagarajan,B, JG Potian, CC Garcia, KHögnason, K Čapková, ST Moe, AR Jacobson, KD Janda& JJ McArdle. Effects ofhydroxamate metalloendoprotease inhibitors on botulinum neurotoxin A poisonedmouse neuromuscular junctions. Neuropharmacology. 2010. March 10. PMID:20211192

  22. Thyagarajan, B, N Krivitskaya, K Högnason, JGPotian, CC Garcia and JJ McArdle. Capsaicin protects functions of mouseneuromuscular junctions from the paralytic effects of botulinum neurotoxin A.J. Pharmacol. Exp. Ther. 2009; Nov; 331(2):361-71. PMID: 19654265.

  23. Patel, RJ, PD Patel, MM Patel, NJ Patel and B Thyagarajan. Mechanisms of potentiation of Angiotensin II-induced contractile response of isolated rat aorta by hydrogen peroxide and tert-butyryl hydroperoxide. Ind. J. Pharmacol. 2009; 41(3): 140-143. PMID: 20442823

  24. Zakharian, E, B Thyagarajan, RJ French, E Pavlov and T Rohacs. Inorganic polyphosphate modulates TRPM8 channels. PLoS ONE. 2009;4(4):e5404

  25. Thyagarajan, B, B Benn, S Christakos and T Rohacs. Phospholipase C mediated regulation of TRPV6 channels: implications in active intestinal Ca2+ transport. Mol Pharmacol. 2009. 75(3):608-16. PMID: 18528787.

  26. Hydrolysis of phosphatidylinositol 4,5-bisphosphate mediates calcium-induced inactivation of TRPV6 channels. Thyagarajan, B, V Lukacs and T Rohacs. J. Biol Chem. 2008. 283(22):14980-7

  27. Lukacs, V, Thyagarajan, B, A Balla, T Balla and T Rohacs. TRPV1 – Regulation b phosphoinositides. The Journal of Neuroscience, June 27, 2007 26 (26): 7070-7080 (First two authors contributed equally). PMID: 17596456

  28. Varnai, P, B Thyagarajan, T Rohacs and T Balla. Rapidly inducible changes in phosphatidyl inositol 4,5-bisphosphate levels to study multiple regulatory functions of the lipid in intact living cells. J Cell Biol. 2006 Nov 6;175(3):377-82. PMID: 17088424.

  29. Baskaran, T, R Malli, K Schmidt, WF Graier and K Groschner. Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling. Br. J. Pharmacol. 2002.137(6):821-30. PMID:12411413

  30. Thyagarajan, B, M Poteser, C Romanin, H Kahr, MX Zhu and K Groschner. Expression of Trp3 determines sensitivity of capacitative Ca2+ entry to nitric oxide and mitochondrial Ca2+ handling. J. Biol. Chem. 2001. 276 (51). 48149-48158. PMID: 11600493

  31. Lintshinger, B, MB Geldsetzer, T Baskaran, WF Graier, C Romanin, MX Zhu and K Groschner. Coassembly of Trp 1 and Trp 3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels. J. Biol. Chem. 2000 Sep 8; 275 (36). 27799-27805. PMID 18002720

  32. Dhanaraju, MD, KS Kumaran, T Baskaran and MS Moorthy. Enhancement of bioavailability of griseofulvin by its complexation with beta-Cyclodextrin. Drug Dev. Ind. Pharm. 1998. 24(6). 583-587


  1. Wang, M, and B Thyagarajan. Pain Pathways and Potential New Targets for Pain Relief. Biotechnology and Applied Biochemistry 2020. Accepted.

  2. Thyagarajan, B. and Foster, MT. Beiging of white adipose tissue as a therapeutic strategy for weight loss in humans. Horm. Mol. Biol. Clin. Investig. 2017. Jun 23;31(2).

  3. Baskaran, P, VKrishnan and B Thyagarajan. Implications of Obesity on Neuromuscular Functions - The known and unknown. BAOJ Obe Weigt Manage 2015, 1:1 1:003

  4. B Thyagarajan and SS Deshpande. Cotrimoxazole and Neonatal Kernicterus: A Review. Drug Chem Toxicol. 2013 Oct 7. PMID: 24099411

  5. Allman E, B Thyagarajan B and KW Nehrke. The Inositol 1,4,5-Trisphosphate Receptor in C. elegans. WIREs Membrane Transport and Signaling. 2012

  6. Rohacs, T, B Thyagarajan and V Lukacs. Phospholipase C mediated modulation of TRPV1 channels. Mol Neurobiol. 2008 Apr-Jun;37(2-3):153-63. PMID: 19073818

  7. Meru, AV, S Mittra, B Thyagarajan and A Chugh. Intermittent claudication: An overview. Atherosclerosis 2006 Aug;187(2):221-37. PMID:16386260


  1. Meier, MK, B Thyagarajan, and R Singh. Consumer’s Opinion on a Pharmacist’s Role in Nutritional Counseling. INNOVATIONS in Pharmacy. Accepted Jan. 2021.

  2. Menghini, M, R Singh, and B Thyagarajan. Understanding Food Preferences and Their Connection to Health Perception among Lean and Non-Lean Populations in a Rural State. INNOVATIONS in Pharmacy, 2020, Vol. 11, No. 4, In press.

  3. Singh, R, L Staubach, J Frantz and B Thyagarajan. Understanding Food Choice, Medication Use and Health From Lean and Non Lean Resident Perspectives in a Rural State. BAOJ Pharm. Sci. 2017, 3: 2 3: 034.