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Project Title: Infection Control and Antibiotic Stewardship Program to Improve Patient’s Outcome.
AMS Intervention Bundle for Critical Care Unit
Antimicrobial therapy is one of the three pillars of an integrated approach to strengthening health systems. Along with infection prevention and control (IPC), medication/patient safety, and antimicrobial use monitoring, AMS helps manage antimicrobial resistance by optimizing antimicrobial use. The execution and implementation of an appropriate and effective AMS intervention bundle for critical care units is necessary in light of the recent pandemic and its associated increased antimicrobial agent usage.
Current projects involve an extensive literature review to identify current concerns in antimicrobial stewardship programs, cross-sectional studies to identify targets for quality improvement in antimicrobial prescribing in critical care areas, developing and implementing context-appropriate AMS interventions followed by periodic post-intervention analyses. The general target of these projects is to improve the antimicrobial prescribing habits within critical care healthcare providers which will reduce antimicrobial agent usage and indirectly influence antimicrobial resistance rates positively.
2. Ventilator Associated Pneumonia (VAP) Prevention Educational Program
Ventilator-associated pneumonia (VAP) is one of the most commonly encountered hospital-acquired infections in intensive care units and is associated with significant morbidity and high costs of care. The pathophysiology, epidemiology, treatment, and prevention of VAP have been extensively studied for decades, but a clear prevention strategy has not yet emerged. Healthcare worker's teaching is an advocated strategy to improve compliance. Developing and implementing of a VAP prevention program for healthcare workers is essential to reduce the VAP rate in intensive care unit. Current projects involve the prevalence study, and cross-sectional pre and post-study to identify the gaps in knowledge and practices. Developing and implementing a training module. The main goal of this study is to improve compliance to VAP bundles which will reduce the rate of VAP.
3. Educational Training Module in Reducing Central Line Associated Bloodstream Infection (CLABSI)
Healthcare associated infections started in the early 1900s, and since then it has become one of the 6th deadliest infections. The occurrence of HAI continues to rise at an alarming rate. The most significant risk to patient safety has been shown to arise from healthcare-associated infections from invasive medical equipment used in the intensive care unit (ICU), particularly central line-associated bloodstream infection (CLABSI), ventilator-associated pneumonia (VAP), and catheter-associated urinary tract infection (CAUTI) continue to constitute a severe threat to particularly Intensive Care Unit (ICU) of low‑and middle‑income countries (LMICs). Developing and implementation of a training bundle is essential to reduce the number of CLABSI especially in intensive care units. Current projects involve the prevalence study, cross sectional pre and post study to identify the gaps in knowledge and practices. Developing and implementing a training module followed by post prevalence study. The main goal of this study is improving the compliance to evidence-based bundles which will reduce the rate of CLABSI.
Researchers:
Universiti Malaya Medical Centre team: Prof Dr Sasheela Sri La Sri Ponnampalavanar (1), Dr Nuryana binti Idris (2), Prof Nor'azim bin Mohd Yunos (3), Prof Rafidah binti Atan (3), Dr Ng Chiu Wan (6), Dr Maznah Dahlui (6), Dr Siti Zuhairah (7), Dr Tang Li Yoong (5), Dr Teo Chin Hai (8), Dr Anjanna Kukreja (1), Dr Sazali bin Basri (7), Dr Nur Alwani Suhaimi (7), Pn Suzana Saibon (7), Pn Haryani Che Hamzah (7), Pn Siti Norintan (7), Sister Prema (7), Sister Siti Shuhaida (7)
Hospital Kuala Kumpur collaborators: Dr Leong Chee Loon(9), Dr Ismaliza binti Ismail(9), Dr Khairil Erwan bin Khalid(9), Dr Nurwahida binti Jamaan(9), Dr Ismail Tan bin Mohd Ali Tan(9), Dr Kee Pei Wei(9), Dr Suliati Sulaiman(9), Dr Rahela Ambaras Khan(9), Ms Tan Sin Yee(9), Mr Andre Ye(9), Weng Hoong(9)
Hospital Tengku Ampuan Rahimah Klang collaborators: Dr Azureen binti Azmel(10), Dr Lee See Pheng(10), Dr Nor Hafizah Mohd Yunus(10), Dr Fun Suet Wen(10), Dr Muhd Arif bin Zainal Abidin(10), Ms Choo Yan Mei(10), Ms Nurish Ezzantie Mishan(10), Pn Nur Shazana binti Ashraf Alisha(10), Pn Shaleha binti Ismail(10), Pn Fatin Naqiah Abd Rahman(10)
Hospital Queen Elizabeth II collaborators: Dr Giri Shan Rajahram(11), Dr Vivy Sudiana Sudeii(11), Dr Abdul Jabbar bin Ismail(11), Dr Cassandra(11), Pn Rosetta Ann Anak Jihen(11), Pn Junaidah Jaidi(11), Matron Roslina Jenang(11),Pn Rosyta Dawat(11), Ms Goh Qing Liang(11), Ms Anith binti A. Aziz (11)
Ministry of Health (MoH) Malaysia collaborator: Dr Farah Bakhtiar (12)
Student(s): Dr Shairil Rahayu(4), Madam Nor Zehan(5), Ms Arulvani Rajandra(1)
Affiliations:
Department of Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Department of Anaesthesiology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Department of Nursing Science, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Department of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Universiti Malaya Medical Centre, Seksyen 13, 50603 Petaling Jaya, Wilayah Persekutuan Kuala Lumpur
Department of Primary Care Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia
Department of Medicine, Hospital Kuala Lumpur, Jalan Pahang, 50586 Kuala Lumpur, Malaysia
Hospital Tengku Ampuan Rahimah Klang, Jalan Langat, 41200 Klang, Selangor, Malaysia
Department of Medicine, Hospital Queen Elizabeth II, Lorong Bersatu, Off Jalan Damai Luyang, 88300 Kota Kinabalu, Sabah, Malaysia
Ministry of Health Malaysia, Aras 3-7, Blok E1 Kompleks E, Pusat Pentadbiran Kerajaan Persekutuan, 62590 Putrajaya, Malaysia
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