TRGS (MY-ERIC)

In this study, we aim to integrate a multifaceted approach to combat multidrug-resistant organisms (MDRO) in the intensive care unit (ICU), with novel technologies, targeted bundle care,  and  behavioral interventions. In brief, the psychosocial of healthcare workers in the ICU will be assessed to provide a better understanding of their practice in order to improve the training program of infection prevention and control. An apta-metabolome sensor will be developed to rapidly detect MDRO while the application of plasma technology will be used to tackle the problem of bacterial persistence in the environment as well as medical devices in hospitals. In addition, antibiotic prescription practice among doctors will also be assessed. Finally, all targeted interventions will be implemented to improve antibiotic prescribing practices and infection control measures in a cluster-randomized controlled trial that involves the ICU in four hospitals. This study will provide novel insights into disease prevention, diagnostics, and patient management strategies. This study could improve patient outcomes by reducing unintended health consequences during hospital stays.