Tissue Engineering & Regenerative Medicine

Major challenges in the field:

  • To chemically modify materials for better adhesion, where spatial control over cell adhesion can be achieved.
  • To develop new approaches to deliver multiple active bio molecules and modulate release profiles from a single delivery system.
  • To develop a new material that can assembled into higher order and respond to stimuli.

We are working on developing silk based scaffolds for regiospecific stem cell differentiation. We are also interested in understanding material properties that can effect stem cell differentiation, cellular attachment and cell growth.

Controlling the Cell Adhesion Property of Silk Films by Graft Polymerization

ACS Applied Materials & Interfaces 2014, 6 (7), 5005.

Modifications of silk film for dual delivery

Biomedical Materials, 2017, 12 (4), 045017

Spatially controlled functional group grafting of silk films to induce osteogenic and chondreogenic differentiation of human mesenchymal stem cells

Materials Science and Engineering: C, 2018,19, 796–805

Self-Patterning Silk Films for Cellular Coculture

ACS Appl. Bio Mater., 2018, 1 (5), pp 1355–1361