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Our initial efforts are focused on first developing in-vitro models mimicking tumour like environment and that can enable study of cancer cell’s invasiveness, microenvironment and growth rates. Towards this, via a microfluidic based technique, we have developed a 3D scaffold with nanoprobes that can sense various micro-environmental changes. Using our platform we are interested in probing the metastasis potential and invasiveness of cancer cells.
Recent work carried out in the lab:
Biocompatible Fluorescent Carbon Dots for Ratiometric Intracellular pH Sensing
Chemistry Select 2017, 2 (20), 5723-5728.
Cell microenvironment pH sensing in 3D microgels using fluorescent carbon dots
ACS Biomaterials Science & Engineering, 2017, 3 (12), 3620-3627
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