Sonoporation is literally the "creation of pores using ultrasound".
Sonoporation uses ultrasound to temporarily increase cell membrane permeability to facilitate the delivery of medication or gene therapy.
In sonoporation microbubbles are injected into the patient that bind with specific receptors on the cell membrane. Highly focused ultrasound is then used to induce the microbubbles to expand and contract or even implode(stable and transient cavitation). The cavitation then induces microscopic openings to appear in the cell membrane.
This increases cell membrane permeability and facilitates the delivery of drugs or gene therapy into the cell.
It really is amazing what ultrasound can do! You can read more about it here.