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The probe sonicators are indispensable for homogenisation and dispersion techniques across Monash's pharmaceutical nanomaterial and formulation development labs. These ultrasonic liquid processors utilise rapid vibrational tip movement to generate powerful shockwaves and high shear forces for disrupting particle agglomerates down to nanoscale sizes. Fully adjustable power output and pulsed sonication cycles prevent thermal heating for temperature-sensitive samples. The ergonomic sound-abating enclosure provides quiet operation, while special jackets facilitate processing small sample volumes. Complemented by a range of micro-tip sizes, the advanced probe sonicators thereby enable superior mixing, deagglomeration, and characterisation of novel nanoemulsions, solid dispersions, lipid vesicles and other nanosystems essential for next-generation oral, topical and intravenous drug delivery research efforts.