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The 3D mixer is an essential technology facilitating efficient non-uniform mixing and dispersion critical for complex dosage form development in the Monash labs. Employing proprietary 3-dimensional motion, high rotating speeds, and interchangeable vessels, the mixer provides much faster integration of powders and pastes than traditional approaches. Unique movement prevents granules and particles from sticking to the sidewalls, allowing total batch homogenisation within minutes. With flexible scale-up (50-gram to 10-kilogram capacity), real-time tracking of energy input, and 21 CFR compliance - the 3D mixer fundamentally enhances pilot plant productivity from direct compression to wet and dry granulation processes used widely across oral drug and controlled release matrix research undertakings. This robust mixing platform promotes greater efficiency, consistency, and innovation of novel pharmaceutical formulations destined to improve patient outcomes.