Molecular and cellular actors involved in human muscle regeneration, in muscle ageing and in muscular dystrophies including oculopharyngeal muscular dystrophy (OPMD) and Duchenne muscular dystrophy (DMD).

Development and growth of muscle and its links; cardiac growth and repair; zebrafish; mechanobiology, stem cells; aging, neuromuscular interaction, cell biology; evolution.

• Role of Wnt / beta-catenin signaling pathway in myogenesis

• Involvement of calpains in myogenesis and muscular dystrophies

• Cell fate choices, cell differentiation, and stem cell generation

• Assembly of body muscles and nerves and the evolution of vertebrate three-dimensional mobility

• Precursor cell development, cell migration, morphogenic movements

Molecular mechanisms and cellular adaptations involved in skeletal muscle regeneration. Understand the ways related to the control of the mitochondrial population and nutrients that can influence the regenerative process.

Role of Ca2+ and nitric oxide signaling in the contractile, metabolic and regenerative functions of skeletal muscles in different conditions (hypoxia, chronic inflammatory disease and aging).

Investigates the genetic basis of skeletal muscle stem cell action during development, evolution, regeneration and disease. Uses the zebrafish as a model organism to understand how skeletal muscle is build and regenerates.  

Understand signaling pathways that control protein synthesis and degradation, organelle biogenesis, autophagy, transcriptional regulation and how these systems reverberate from muscles to the entire body for healthy aging.

​​Physiology, with emphasis on Metabolism, mainly in the following themes: muscle atrophy and hypertrophy, autophagy and signaling mediated by GPCRs.

Cellular and molecular biology and bioinformatic methods for data mining and big data analysis, mainly in the study of molecular pathways involved in cancer-associated cachexia.

Cellular and molecular control of skeletal and cardiac muscle function and remodeling in physical training in heart failure and cancer.

• Dissection of cellular communication during muscle ageing, fibrosis and regeneration

• Development of therapeutic approaches.

Translational research identifying novel therapies for children with muscular dystrophy. Role of extracellular matrix and integrin signaling in muscle development and disease.