Student: Ethan Blank
Project Mentors: Dr. Brent Vernon – SBHSE
Dr. Claire Honeycutt – SBHSE
Dr. Jessica Weaver – SBHSE
YouTube Link: View the video link below before joining the zoom meeting
Zoom Link: https://asu.zoom.us/j/98243875228
Abstract
The leading cause of death or potential reduced life expectancy for people under the age of 65 in the United States is traumatic injuries. Traumatic wounds comprise a wide range of possible injuries, but commonly include high levels of blood loss. Hemostasis is pertinent to the process of wound healing. In the occurrence of a major traumatic wound, hemostasis may not be achieved properly causing considerable complications. Fibrin sealants have indications from the FDA in three crucial categories for wound healing applications, including blood clotting, providing a sealing barrier, and adhesive bonding. Fibrin sealants are synthesized by utilizing two components of the coagulation mechanism in the blood, where thrombin is added to fibrinogen and converted into a fibrin clot network. In this project, external traumatic wounds are targeted using a fibrin sealant loaded with antibiotic and local anesthetic for treatment.