Team 29
Southwest Endovascular: Anti-Refluxing and Plug Promoting Detachable Tip on Microcatheter for Onyx Delivery
Southwest Endovascular: Anti-Refluxing and Plug Promoting Detachable Tip on Microcatheter for Onyx Delivery
Team Members: Salma Leyasi, Edgar Manriquez-Sandoval, Margaret Miller, Samuel Rios - SBHSE
Team Mentors: Dr. Todd Abruzzo - Phoenix Children’s Hospital
Dr. Brent Vernon - SBHSE
YouTube Link: View the video link below before joining the zoom meeting
Zoom Link: https://asu.zoom.us/j/99264248460
Abstract
Arteriovenous Malformations (AVM) are abnormal tangles of blood vessels connecting arteries and veins in the brain. Around half of all AVM patients experience hemorrhagic strokes and irreversible brain damage due to disrupted blood flow. The current treatment for AVMs utilizes an embolizing agent which is administered via a transarterial microcatheter and solidifies upon contact with the blood. However, these microcatheters can become clogged at the tip during the step of the procedure where the AVM is being isolated from the blood flow but has not yet been filled. Surgeons must then completely remove the clogged microcatheter from the feeding artery and replace it with a new one in a different feeding artery which increases the risk to the patient and time to the procedure. We propose a solution that cuts the blood supply to the AVM while allowing surgeons to fill the remaining vasculature without having to reposition the microcatheter, reducing the risk to patients. Southwest Endovascular has accomplished this in the MohaveTM microcatheter prototype by implementing novel geometry which promotes the formation of an anti-reflux plug at the tip with radial ports and a central distal port to allow for filling of the AVM. Our design allows for the precise execution of the Plug and Push method by the use of a plug membrane. First, the distal end is plugged with the membrane creating the anti-reflux plug when the embolizing agent is pushed in. Once a reliable plug is formed, the membrane is broken and the distal end is free for an embolizing agent to fill the AVM. The tip becomes trapped in the AVM embolus and is left implanted in the patient, allowing for safe removal with minimal force.
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