sdj-10073

Melanotic Neuroectodermal Tumor of Infant: Two Case Reports from Sulaimani

* Marwa A. Hamied, Salwa M. Al-Shaikhani, *Balkees T. Garib, ***Suha N. Aloosi

* Department of Oral Diagnosis, College of Dentistry, University of Sulaimani, Sulaimani, Iraq.

** Department of Dental Nursing, Sulaimani Technical Institute, Sulaimani Polytechnic University, Sulaimani, Iraq.

*** Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Sulaimani, Sulaimani, Iraq.

Submitted: 15/03/2018; Accepted: 20/05/2018; Published 31/08/2018

DOI: https://doi.org/10.17656/sdj.10073

Abstract

Melanotic neuroectodermal tumor of infancy is a rare osteolytic-pigmented neoplasm that primarily affects the maxilla of newborn infants. Two cases of melanotic neuroectodermal tumor of infancy were presented to the department of oral and maxillofacial pathology in Sulaimani Dental College, 2015. Clinical assessment and histologic diagnosis of the classic findings supported the final diagnosis, and no recurrence was detected after one year follow up.

Keywords: Melanin tumor, Maxilla, Benign, Infant. 

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References:

1. Krompecher E. Zur histogene und morphologic den adamantinoma und sonstiger kiefergeschwulste. Beitr Pathol Anat. 1918;64:165-97.

2. Kilmer JB. The pigmented ameloblastomas or "retinal anlage" tumors. Report of two cases. Laryngoscope. 1963;73:1303-08. 

3. Allen MS, Harrison W, Jahrsdoerfer RA. "Retinal anlage" tumors. Melanotic progonoma, melanotic adamantinoma, pigmented epulis, melanotic neuroectodermal tumor of infancy, a benign melanotic tumor of infancy. Am J Clin Pathol 1969;51(3):309-14. 

4. Lurie HI. Congenital melanocarcinoma, melanotic adamantinoma, retinal anlage tumor, progonoma, and pigmented epulis of infancy. Summary and review of the literature and report of the first case in an adult. Cancer. 1961;14:1090-108.

5. Kruse-Lösler B, Gaertner C, Bürger H, Seper L, Joos U, Kleinheinz J. Melanotic neuroectodermal tumor of infancy: systematic review of the literature and presentation of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006; 102(2):204-16.

6. Soft tissue tumors. In: Neville BW, Damm DD, Allen CM, Chi AC, (editors). Oral and Maxillofacial Pathology. 4th ed. Canada: Saunders; 2016. ISBN:978-1-4557-7052-6.pp.499-500.

7. Agarawal P, Agarawal V, Raina VK. Melanotic neuroectodermal tumor of infancy: Case report of an unusual tumor. Indian J Plastic Surg. 2003; 36(2):123-25.

8. Piperi EP, Rake SA, Tosios KI, Vasilopoulou EE, Rake AP, Sandler NA, et al. a Mandibular melanotic neuroectodermal tumor of infancy treated conservatively with enucleation. J Craniofac Surg. 2010;21(3):685-88.

9. Krishnamurthy A, Vaidhyanathan A, Majhi U. Malignant melanotic neuroectodermal tumor of infancy arising in the mandible. J Cancer Res Ther. 2011;7(3):368-72.

10. Goncalves CF, Costa Ndo L, Oliveira-Neto HH, Jesus LA, Sant'Ana SS, Leles JL, et al. a Melanotic neuroectodermal tumor of infancy: report of 2 cases. J Oral Maxillofac Surg. 2010;68(9):2341-46.

11. Naidoo J, Potgieter L, Wieselthaler N, Pillay K. Melanotic neuroectodermal tumor of infancy, a rare cause for a bump on the head. Childs Nerv Syst. 2013;29(1):167-72.

12. Haque S, McCarville MB, Sebire N, McHugh K. Melanotic neuroectodermal tumor of infancy: CT and MR findings. Pediatr Radiol. 2012;42(6):699-05.

13. Béogo R, Nikiéma Z, Traoré SS, Bouletreau P. Maxillary melanotic neuroectodermal tumor of infancy management: is conservative surgery the best approach?. J Craniofac Surg. 2013;24(4):338-40.

14. Agarwal P, Saxena S, Kumar S, Gupta R. Melanotic neuroectodermal tumor of infancy: Presentation of a case affecting the maxilla. J Oral Maxillofac Pathol. 2010;14(1):29-32.

15. Kapadia SB, Frisman DM, Hitchcock CL, Ellis GL, Popek EJ. Melanotic neuroectodermal tumor of infancy. Clinicopathological, immunohistochemical, and flow cytometric study. Am J Surg Pathol. 1993;17(6):566-73.

16. Johnson RE, Scheithauer BW, Dahlin DC. Melanotic neuroectodermal tumor of infancy. A review of seven cases. Cancer. 1983;52(4):661-66. 

17. Halpert B, Patzer R. Maxillary tumor of retinal anlage. Surgery. 1947;22(5):837-41.

18. Haque S, McCarville MB, Sebire N, McHugh K. Melanotic neuroectodermal tumor of infancy: CT and MR findings. Pediatr Radiol. 2012;42(6):699-705.

19. Fowler DJ, Chisholm J, Roebuck D, Newman L, Malone M, Sebire NJ. Melanotic neuroectodermal tumor of infancy: clinical, radiological, and pathological features. Fetal Pediatr Pathol. 2006;25(2):59-72.

20. Surgical pathology of the head and neck. Barnes L (editor). 2nd ed. New York, USA. Marcel Dekker, 2001, pp 991-95.

21. Higashi K, Ogawa T, Onuma M, Usubuchi H, Imai Y, Takata I, et al. Clinicopathological features of melanotic neuroectodermal tumor of infancy: Report of two cases. Auris Nasus Larynx. 2016;43(4):451-54.

22. Bhulaxmi P, Salma M, Sreekanth K, Abdullahin SK Melanotic Neuroectodermal Tumor of Infancy (MNTI) – A case report. IJBR. 2015;6(5):349-52.

23. Tendon PN, Sah K, Kale A, Kadam A, Shah H, Chandra S. Melanotic neuroectodermal tumor of infancy: Report of a case associated with high urinary excretion of Vanilmandelic acid. Contemp Clin Dent. 2011;2(4):337-41.

24. Bangi BB, Tejasvi ML. Melanotic neuroectodermal tumor of infancy: A rare case report with differential diagnosis and review of the literature. Contemp Clin Dent. 2012;3(1):108-12.

25. Madrid C, Aziza J, Hlali A, Bouferrache K, Abarca M. Melanotic neuroectodermal tumor of infancy: A case report and review of the aetiopathogenic hypotheses. Med Oral Patol Oral Cir Bucal. 2010;15(5):e739-42. 

26. Barrett AW, Morgan M, Ramsay AD, Farthing PM, Newman L, Speight PM. Clinicopathologic and immunohistochemical analysis of melanotic neuroectodermal tumor of infancy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002; 93(6):688-98.

27. Tam J, Cheung WS, Senger C, Reichman M, Campbell KM.  Melanotic Neuroectodermal Tumour of Infancy: A Case Report. J Can Dent Assoc. 2015;81:f7.

28. Neven J, Hulsbergen-van der Kaa C, Groot-Loonen J, de Wilde PC, Merkx MA. Recurrent melanotic neuroectodermal tumor of infancy: A proposal for treatment protocol with surgery and adjuvant chemotherapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(4):493-96. 

29. Hamilton S, Macrae D, Agrawal S, Matic D. Melanotic neuroectodermal tumor of infancy. Can J Plast Surg. 2008;16(1):41-44.

30. Jain P, Saxena S, Aryya NC. Melanotic neuroectodermal tumor of infancy: A rare maxillary alveolar tumor. Eur J Plast Surg. 2003;26(1):35-37.

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