CHY 252

Organic Chemistry Laboratory I - CHY 252

Chalcone Synthesis

 Documents, Instructions, and Useful Websites

syllabus - Tracy (pdf)

project overview (pdf)

project reaction scheme (pdf)

schedule (pdf) 

MIT techniques videos:

TLC

organic extraction

column chromatography

recrystallization

USM Laboratory Safety Plan

MSDS search site

laboratory check-in list (pdf)

laboratory housekeeping (pdf)

Thin Layer Chromatography resources:

solvent polarity (pdf)

getting to know TLC (pdf)

Infrared Absorption Spectroscopy resources:

characteristic IR absorptions (pdf)

brief IR operation instructions (pdf)

Nuclear Magnetic Resonance Spectroscopy resources:

Varian 60MHz NMR operation instructions (pdf)

abbreviated NMR instrument instructions (pdf)

chemical shifts in 1H and 13C NMR spectra (pdf)

some addition 13C NMR chemical shifts (pdf)

Mass Spectroscopy resources:

GC/MS sample preparation (pdf)

mass spectroscopy homework (pdf)

DATA BASE OF SPECTRA

SDBS: Intgreated Spectral Data Base System for Organic Compounds

LABORATORY NOTEBOOKS and FINAL REPORTS

Laboratory Notebooks:

lab notebook guide (pdf)

lab notebook example (pdf)

lab notes rubric (pdf)

Final Reports:

instructions for final reports (pdf)

conclusion example (pdf)

final report example (pdf)

final report rubric (pdf)

Literature Assignment:

chalcone article (pdf)

chalcone literature assignment (pdf)

LABORATORY HANDOUTS: (all documents are pdf files)

Introduction to Thin Layer Chromatography

TLC_Intro TLC_Worksheet

Unit 1:  Synthesis of Benzaldehyde

U1_Procedure U1_Pre-Lab U1_Post-Lab

benzaldehyde & benzyl alcohol_IR_spectrum

Unit 2:  Synthesis of 1-Phenylethanol

U2_Procedure U2_Pre-Lab U2_Post-Lab

Unit 3:  Synthesis of Acetophenone

U3_Procedure U3_Pre-Lab U3_Post-Lab

acetophenone_13C_NMR_spectrum

Unit 4:  Synthesis of Chalcone

U4_Procedure U4_Pre-Lab U4_Post-Lab

trans-chalcone_13C_NMR_spectrum

Unit 5:  Synthesis of Substituted Chalcone

U5_Procedure U5_Pre-Lab U5_Post-Lab