Prof. Dale Srinivas
is
The Pride of Guyana
Prof. Dale Srinivas is World Champion in Pharmacology.
Question: What inspired you to enter into Pharmacology?
Answer: INFACT SINCE CHILD HOOD I WOULD LIKE TO ERADICATE SOME DISEASES BEFORE I ENTER IN TO MEDICINE I HAD PhD AND 3 POST DOCS IN THE UNITED STATES IN CHEMISTRY AND BIOMEDICAL RESEARCH AT BIOCHEMISTRY AND PHARMACOLOGY DIVISION WHERE I GET OPPORTUNITY WORK ON APOPTOSIS AND STEM CELL RESEARCH . , I CAME TO USA /WESTERN WORLD TO WIN NOBEL PRIZE AS A PhD AND MD I WILL HAVE TWO OPTIONS 1.CHEMISTRY 2. PHYSIOLOGY .TO CHANGE FUNCTIONS THROUGH BIOCHEMICAL MEANS AGONISTIC AND ANTAGONISTIC PATHWAYS NEEDED THESE WILL COME FROM PHARMACOLOGY AND ALSO CHEMISTRY BASE FOR PHARMACOLOGY . ACTUALLY SCIENCE ONLY ONE IN THAT PHARMACOLOGY IS A BRANCH WHICH BRINGS PHYSIOLOGICAL CHANGES WHICH HELPS MANKIND TO COME OUT OF FROM DIFFERENT DISEASES LIKE COVID , HIV ,INF. CANCER DIAB.HTN AND BACTERIAL AND VIRAL ETC
Question: Since how long, you have been into this Synthetic Organic Chemistry and Health Sciences and in which cities you have been associated for administration, entrepreneurship, teaching, research, commercial and training programs?
Answer:
SINCE 1988 I HAVE BEEN IN SYNTHETIC ORGANIC CHEMISTRY I USED TO WORK AT SOUTH INDIAN RESEARCH INSTITUTES TO MANUFACTURESMX/TMP , ISOPROTURON AND SEVERAL DRUGS . AT IICT HYDERABAD WE HAVE DEVELOPED PROCESSES FOR TAMOXIFEN CITRATE , CITRIAZINE , KAIROMONES AND SOME PHEROMONES AND WATER PURIFICATION SYSTEMS ETC IN HEALTH SCIENCES SINCE 2006 TO TODATE I WAS TEACHING AT DIFFERENT UNIVERSITIES WORKING ON STEM CELL RESEARCH , NANOTECHNOLOGY AND SEVERAL NEW METHODOLOGIES ETC
ADMIN : CURRENTLY IAM VICE CHANCELLOR , RESEARCH SCIENTIST FOR TWIN ISLAND UNIVERSITY,DEAN AMERICAN SCHOOL OF MEDICINE AND PROF AT 5 MEDICAL SCHOOLS TO TEACH ARTIFICIAL INTELIGENCE, BIOCHEM, PHARMACOLOGY IMMUNOLOGY,GENTICS ,EPIDEMIOLOGY AND NEUROSCIENCES ETC
ENTREPRENEURSHIP : MANAGER AND PARTNER FOR SENSOR SCIENTIFIC LTD , ADVISER/ PARTNER FOR PERFUME /OIL MANUFACTURING COMPANY , VICE PRESIDENT OF RAJIV GANDHI UNIVERSITY OF SCIENCE AND TECHNOLOGY, OWNER OF TWINISLAND UNIVERSITY ,AND PARTNER OF AMERICAN SCHOOL OF MEDICINE ETC
TEACHING AT DIFFERENT MEDSCHOOLS AND UNIVERSITIES SINCE 1990 ONWARDS IN DIFFERENT COUNTRIES
RESEARCH IS ALWAYS ON SO FAR I PUBLISHED MORE THANS 70 INTERNATIONAL PUBLICATIONS
COMMERCIAL AND TRAINING PROGRAMS FOR COMMERICIAL I TRAINED JAWA PROGRAMERS TRAINED DOCTORS AT LEAST 10000.I HAVEON THE GIVE SOME PhDS AND CONSULTANT FOR CHEMICAL COMPANIES
Question: What are your future plans for administration, entrepreneurship, teaching, research and training programs in Pharmacology and Health Sciences?
Answer:
FUTURE PLANS WOULD LIKE TO WORK ON RESEARCH PROJECTS WHICH CAN LEAD TO WINNING NOBEL PRIZE IN PHYSIOLOGY /CHEMISTRY . WE ARE WORKING ON AN APP WHICH CAN GIVE DATA BASE AND PHARMACOLOGICAL/DIAGNOSTIC INFORMATION TO DOCTORS , HEAMOJOIN SENSORS , SENSORS FOR MI, DB, HTN ETC, SENSORS FOR OXYGEN LEVELS IN CORONA ETC
Question: Please introduce yourself and How do you want to be remembered / known in world?
Answer: I AM DR DALE SRINIVAS MDPHD,MSMBA LLB,FRSC A HARD CORE RESEARCH SCIENTIST PROBABLY NOBEL LAURETTE PROBABLY REMEMBERED LIKE EINSTEIN /NEWTON AND JC BOSE HG KHORANA ., IF MY RESEARCH HELPS TO ERADICATE DISEASES TO HELP MANKIND /ANIMAL/PLANT KINGDOMS I WILL BE HAPPY
Question: What kind of businesses can be started in Sensor Technology? What minimum infrastructure would it need?
Answer: MAKING MI SENSORS , NITRIC OXIDE (NO) SENSORS TO TREAT (CORONA) VIRUSES , SENSORS FOR DIAGNOSTIC PURPOSES BY USING BIOMARKERS TREPONENE , CREATININE BUN HEAMOJOIN ETC WHICH CAN AT LEAST RAISE ONE BILLION DOLLARS AND PROVIDE AN EMPLOYMENT FOR 1000 PEOPLE. I WAS PART OF ESTABLISHING 15 UNIVERSITIES THROUGH OUT THE WORLD . PRESENTLY IAM RUNNING TWO UNIVERSITIES AND OIL /PERFUME COMPANIES /VIJAYS MEDICAL SUPPLIES ALSO
INFRASTRUCTURE A GOOD WELL EQUIPPED RESEARCH LAB AND AN ATTACHED HOSPITAL FOR STUDIES /CONDUCTING CLINICAL RESEARCH .AND R&D WITH AL CHEMICALS, I NEED TO GET ONE OR TWO NIH PROJECTS AND IN INDIA NEED TO GET CSIR PROJECT AND SOME COMPANY SPONSORSHIPS ETC
Question: What are your recommendations to improve the standards of journals publishing research articles on Pharmacology?
Answer: STANDARDS ARE GOOD AT AMERICAN AND BRITISH JOURNALS ESPECIALLY ALL ACS JORUNALS JMC, JACS, JOC , NATURE CELL , SCIENCE ANGIE WANDECHEMIE , NATURE DRUG DISCOVERY , PHARMCOLOGICAL REVIEWS , TRENDS IN PHARMACOLGICAL SCIENCE ETC . MOST OF THE PEOPLE ARE STANDARD DEVIATION METHODS GET THE DATA FROM EPIDEMIOOGY AND MAKING TABLES AND IGNORING OTHER INTEREACTIONS OF THE DRUGS.t1/2, XENOBIOTIC EFFECTS AND SIDE REACTIONS IMPACT OF THESE HAVE BEEN IGNORED IN RESEARCH PAPERS . ARTICLES SHOULD NOT BE TOO BIG SO THAT PEOPLE CAN READ EASILY .
Question: What are your recommendations to improve syllabus of Pharmacology for more creativity, applications and opportunities?
Answer: CHEMISTRY KNOWLEDGE OF KNOWING DRUG STRUCTURE AND ITS ACTIVITY ANRTUNITIESD RESISTANCE ETC NANOMEDICINE , ARTIFICIAL INTELIGENCE AND NEW INVENTIONS AND DISCOVERIES SHOULD BE ADDED INTEGREATED MEDICINE ALSO SHOULD BE ENCOURAGED RECENTLY INDIAN PM MODI, AND MR TEDROS WHO CHIEF STARTED A PROJECT IN INDIA FOR DEVELOPING INTEGRATED MEDICINE AND ANCIENT HERBS FROM AYURVEDA AND OTHERS .WE NEED TO OXYGENATE WORLD , OXYGEN PARKS SHOULD BE ENCOURAGED IN THE WORLD .MORE OXYGEN PROVIDING PLANTS SHOULD BE PLANTED PHARMACOLOGY STARTED IN SCHOOLS EARLY .PRIVATE AND PUBIC SECTOR SHOULD APPOINT PHARMACOLOGISTS . THERE ARE SEVERAL OPPORTUNITIES EXISTS FOR PHARMACOLOGISTS AS LONG AS DISEASES EXISTS PHARMACOLOGISTS NEEDED DOCTORS SHOULD TAKE PHARMACOLOGISTS HELP WHILE TREATING PATIENTS
Question: What are Blood Brain Barriers and Other Barriers? How medicines are developed to cross such barrier?
Answer: BLOOD BRAIN BARRIER, BLOOD GAS BARRIER BLOOD TESTIS BARRIER , BLOOD PLACENTAL BARRIER AND BLOODGLAND BARRIER ALL WILL BARRIER WILL ALLOW NONPOLAR MEDICINES TO ONLY . WE HAVE TO MAKE POLAR TO NON POLAR VIA ORGANIC TRANSFORMATIONS WITHOUT LOOSING ACTIVITY OR USING NANOZYMEWHICH MAKES/ DRAGS POLAR MOLECULE TO PASS THROUGH BARRIER .ITS OUR OWN TECHNOLOGY
Question: What are your recommendations to frame guidelines on funding of research projects on Signal transduction?
Answer:
WE NEED TO GET PROJECTS TO CONDUCT SIGNALTRANSDUCTION RESEARCH IN RELATION TO EVERY DISEASES WHICH EVENTUALLY HELPS BIOMEDICAL RESEARCH TOMAKE PHARMCOLOGICAL STUDIES MORE EASIER
Question: How can universities produce revolutionary PhD and Post Doc thesis and dissertations on Pharmacology? What are your recommendations to improve the academic standards?
Answer: FOR EVERY RESEARCH BASIC SCIENCE RESEARCH IS THE KEY FACTOR IF WE APPLY BASIC RESEARCH IN TO CLINICAL RESEARCH SO THAT WE CAN RESOLVE PHARMACO KINETICS AND PHARMCO DYNAMICS PROBLEMS EVENTUALLY IT LEADS TO SOCIETAL USAGE
Question: What are your views on SUZUKI COUPLING?
Answer: SUZUKI IS THE MILDER VERSION OF STILLE WHERE BORON REPLACING Sn, BUT OUR 2,3 DIHYDROXY BORONATES SUZUKI COUPLING THE IS UNIQUE YIELDS ARE LESS . FOR EXAMPLE 2, 3 DIHYDROXY BORONATES COMING FROM ALLYL BORONATE WITH SAD /ADMIX REACTIONS COUPLE TO VINYL/ARYL HALIDES IN SUZUKI CONDITION A METHYLENE /SP3 CARBON HAVING 2, 3 HYDROXY GROUPS COUPLIED TO VINYL GROUP . IN NO WAYWITH EXISTING CHEMISTRY WE CAN TRANSFER 2,3 HYDROXY BORONATES . IF ANY BODY ATTEMPTS OTHER METHOD EXCEPT OURS 2,3 HYDROXY BORONATES WILL UNDERGO INTRAMOLECULAR ELIMINATION WILL BECOME ALLYL ALCOHOLS HERE ALSO WE CHANGE CHEMISTRY COMPLETELY
FIRST TIME WE USED OXYGEN OF BORON TO FUNCTIONALISE NBS REACTIONS THAT MEANS AB , ABC SYSTEMS ONLY EXISTING SO FAR IN THE WORLD BUT BORONOLACTONISATION BECOMES ABD/ABE (ABX) STERIOCHEMISTRY ALSO CHANGING. SOFAR OXYGEN OF CARBON EXISTS IN IODOACTONISATION REACTIONS OXYGEN OF BORON WE USED .
PRESENTLY WE ARE CONCENTRATING ON AD MIX REACTIONS ON DIFFERENT REACTIONS ALLYL AND OTHER BORONATES ETC
Question: How can students seek job and career opportunities in New Diagnostic Methods?
Answer:
AS I SAID SCIENCE IS ONLY ONE PATIENT CARE FIRST PRIORITY . SEVERAL NEW DISEASES ARE COMING COVID ,EBOLA MONKEY POX HIV AND DIFFERENT KINDS OF CANCERS AND MIS ETC NEEDED BETTER EASIER AND TIME SAVING DIAGNOSTING METHODS . UNTIL NOW PCR IS TAKING ONE DAY IN CORONA DIAGNOSIS THERE IS NEED FOR FASTER METHODS OR SENSOR TECHNOLOGY BEFORE A PATIENT ENTERS INTO THE DOCTORS OFFICE DOCTOR SHOULD KNOW WITH GREEN LIGHT OR RED LIGHT IF PATIENT IS POSITIVE CASE OR NOT .
Question: What job titles are available in Cancer research?
Answer:
ONCOLOGIST, SCIENTIST, CHEMOTHERAPIST RADIO THERAPESUTETC
Question: Which are Typical employers in Stem cell research?
Answer:
STEM CELLS ARE ACTIVE AT YOUNGER INDUALLS OLDER STEM CELLS NOT WORKING PROPERLY STILL I BELIEVE BY USING PHARMACOLOGICAL METHODS /CERTAIN CHEMICALS WE CAN ACTIVATE /MANIPULATE STEM CELLS
Question: Which are the courses available in Pharmacology?
Answer
PHARMACOLOGY, PHARMCEUTICAL SCIENCE , MEDICINAL ORGANIC
Question: What are your recommendations to write a world class research article in Pharmacology? What essential components and factors must be there?
Answer IT SHOULD BE A BIOMEDICAL RESEARCH ONY .CHEMISTRY , MECHANISM OF ACTIONS EPIDEMIOLOGY FACTORS USAGE FOR MANKIND AND EFFECTS SHOULD BE INVOLVED
Question: What are your recommendations to establish a world class research institute for Pharmacology?
Answer
BEST RESEARCH TESTINGCENTER SHOULD BE ESTABLISHED PHARMACOLOGY RESEARCH INSTITUTE SHOULD HAVE ORGANIC CHEMSITRY LAB ATTACHED AND ATTACHED HOSPITAL FOR CLINICAL RESEARCH AND TOXICOLOGY UNIT AND COLABORATION WITH OTHER FACULTIES NEEDED
Question: What are your recommendations to improve employment and scope in Solar cell Energy project?
Answer: ADVOCACY NEEDED FOR SOLAR PROJECTS
STORING BATTERY CAPACITIES SHOULD BE INCREASED
YES NOT ONLY ECO/ENVIRONMENTAL FRIENDLY NO POLLUTION WE NEED TO CHANGE THE GOVT POLICY
Question: Would you start a campaign to request government to offer free of cost internet to all people of your country as fundamental right, because it plays a significant role in education, awareness, implementation of government policies and economic development of country?
Answer: YES FREE INTERNET WILL HAVE TREMENDOUS IMPACT ON EDUCATION , AWARENESS AND IMPLEMENTATION OF GOVT POLICIES
Question: What are your recommendations to authors, who are writing Books on Pharmacology for more creativity and understanding of the subject?
Answer: THEY HAVE TO INCLUDE CASE STUDIES , MECHANISMS OF CHEMITRY SHOULD BE EXPLAINED
Question: What according to you are the Top 5 major challenges (research problems) which need to be resolved urgently by world’s scientists in the area of Pharmacology?
Answer:
FUNDING
INFRASTRUCTURE
RESEARCHERS
RESEARCH GUIDES
ADVOCACY
RESEARCH TRAINING FROM HIGH SCHOOL LEVELS
Question: What are your recommendations to improve standards of Conferences in Pharmacology? How can they be brainstorming and more creative?
Answer: THEY NEED TO GIVE CHANCES SO GOOD RESEARCH WILL COME OUT
Question: Which major challenges do you see to establish Brazil as world leader in Pharmacology?
Answer: BRAZIL GOT GREAT POTENTIAL , NEEDS TO FOCUS ON EXPLORING MORE LIKE AMAZON FOREST MEDICINAL PLANTS IN COVID TIME WE LOOSE LOT DUE TO INFRASRUCTURE OXYGEN PLANTS , WE NEED TO PUT SOME INDUSTRIESTO MAKE MEDICINES ,OXYGEN PLANTS , OXYGEN PARKS WE NEED TO ADOPT PORTUGUES ALSO ALL ENGLISH INFORMATION SHOULD BE TRANSLATED IN TO PORTUGUES,SANSKRIT AND SPANISH
Question: Any other thing, you would like to share with World?
Answer:
YES EVERY RESEARCHER IN THE WORLD HAVE TO HAVE GREAT GOALS AT LEAST PUT AN EFFORT FOR NOBEL PRIZE RESEARCH FOR RESOLVING PROBLEMS KNOWN TO UNKNOWN SEARCH FOR THE TRUTH NOT COPYING SCIENTISTS SHOULD WORK FOR MAN KIND NOT FOR MONEY SHOULD NOT MANIPULATE RESULTS . HEALTHY COMPETITION IS NEEDED AMONG THE SCIENTIFIC FRATERNITY SCIENTISTS SHOULD NOT PLAY DIRTY POLITICS /DESTRUCTIVE POLICTICS THEY SHOULD ADOPT CONSTRUCTIVE CRITICISM HELP/COLLABORATE TO RESOLVE PROBLEMS
Dale Srinivas
X Faculty of Health Sciences.
University of Guyana
Presently in Guyana/Brazil
.
Work Experience
Twin Island University's Vice Chancellor Prof. Dale Srinivas From Guyana Wins At World Championship In Pharmacology
♦ Twin island university vice chancellor since 2014 till to date
Basic Science Dean of American International School Of Medicine
Prof. at AISM in Pharmacology and Green heart Medical University and Prof. at American University of Peace Studies
Lecturer at university of west indies St Augustine campis at Trinidad
University of Guyana as lecturer II 2008-2015© taught several subjects like pharmacology , biochem, physiology chemistry neurosciences genetics behavioral science pharmaceutical and natural products
♦ Part time Lecturer at UG /Associate Dean and Director of operations at Local off shore Medical school (GMU) Feb 2008- OCT 2008 .
♦ Full time lecturer used to teach neuroanatomy /Physiology /Biochemistry/Pathology and Behavioural science At Burnet International Medical School Haiti May 2005 –2006 Jan .
♦ Part time research consultant for Sensor Scientific Ltd. An American company which used to be in Stkitts. Got experience in making thermistors , different types of sensors etc. Duration 2000---2002 Dec, while full time Medical student at Windsor university .
♦ Post doctoral fellow at South western medical center , Biochemistry and pharmacology Department 1997—1999 , worked on Boron , IP3 , Arachidonic acid purification , sharpless Assymetric dihydorxylation , Suzuki coupling etc .
♦Short time Post doctoral fellow SMU, Oxford Mississippi worked on Artimycin and cephalosporins analogs and signal transduction
♦ Doctoral fellow at Indian institute of chemical technology 1992 – 1997 worked on Taxol research and developed different types methodologies developed New reagents .
M.BA ,Mumbai finished in Hospital management .LLB recently completed .
ACADEMIC ACHIEVEMENTS
1) FIRST TIME CREATED AB to ABX SYSTEM (OXYGEN OF BORONIC ACID IS USED FUNCTIONALISED NBS REACTIONS )
2) ALLYL BORONATES /ADMIX REACTIONS AND CONDUCTING SUZUKI COUPLING (WHICH IS NOT POSSIBLE THROUGH EXISTING CHEMICAL METHODS )
3) CHEMICAL/BIOCHEMICAL REACTIONS WITH NANOZYMES
4) MAKING SEVERAL REAGENTS IN CLAY CATLYSIS CLAYAN, CLAYSIN ,CLAYCOPP CLAYAC ETC AND MAKING CHEMICAL REACTIONS
5) FIRST ENANTIOSELECTIVE SYNTHEIS OF DIEPOXIDE AND ITS DEOXYGENATION TO GET 1,3 DIOL WITH AN OLEFINIC EXTENTION
6) MICHEAL WITTING REACTIONS INSITU USED, RADICAL CYCLISATION , WITTIG REARRANGEMENT CLAISENCONDENDENSATIONS,HORIZONTAL CLEAVAGE OF TAXOL/ USED FOR TAXOL SYNTHESIS
7) FIRST NH4CL AND ALCL3 FOR ENEVIRONMENTSL FRIENDLY REAGENTS FOR PROTECION AND DEPROTECTION SEVERAL GROUPS
8) PHOTOCHEMICAL AND MICROWAVE REACTIONS USING FOR SYNTHESIS OF DIFFERENT NATURAL PRODUCTS
9) TITANIUMAND ZIRCHONIUM INDIUM AND NICKEL USED IN ORGANIC SYNTHEIS OF DIFFERENT NATURAL PRODUCTS
10) NEW DIAGNOSTIC METHODS FOR DB,HTN MALRIA ETC
11) NANOPARTICLES USED IN PASSING THROUGH BLOOD BRAIN BARRIERS AND OTHER BARRIERS
12) A NEW WAY TO SYNTHSIZE THE TAMOXIFEN CITRATE AND MANUFACTURING PROCESS DEVELOPED
13) ALLOSTERIC EFFECTS AND OLIGOMER SYNTHESIS AND SEVERAL EXPLORED AND MORE
Research interests
1) Nanotechnology applications to medicine and other areas.
2) RNA research
3) Stem cell research
4) Hemozoin ; A new method for malaria diagnosis
5) Organometalics
6) Cancer research
7) Clay catalysis
8) Signal transduction
9) Solar cell Energy project
10) Bioethanol and WTE projects
11) Assymetric synthesis
12) Apoptosis
13) Suzuki coupling applications in natural products
Academic Background
♦ PhD in Synthetic Organic Chemistry, Osmania University, Hyderabad, worked with Dr. Yadav , Director , Indian Institute of ChemicalTechnology, Hyderabad 500007,India. and also worked as post doctoralfellow withProf Falck at UT south westernmedical center, Dallas Texas 75235(US).
Second PDF done with southern Methodist and oxford missisipi university .
♦ M.D at Windsor university,( off shore medical university ) Stkitts,West Indies.
M.B.B.S (A.M) India .
MBA in Hospital Management
♦ Masters In Organic Chemistry Osmania University
Research Experience
-Process developed for the manufacture of tamoxifen citrate (anti breast cancer drug), Ondoncetron (antiemetic drug)akairamones (insect hormones) widely applicable for rice and cotton pests.
-An efficient approach for highly functionalizedTexel ‘ABC ‘skeleton was accomplished by employing Wittig rearrangement as the key step.
-Approaches for TaxolSkeleton; A study on Diels-Alder vs.ENE reaction
-A short and efficient fully functionalized synthesis of Taxol A ring.
-Radical induced cyclisation from A to AB rings of Taxol
- Titanocene Mediated new synthetic Methods
1) Regio-selective reduction of vinyl Epoxides
2) Epoxy allyl alcohols to dienols
3) Diepoxy alcohols to 1ene 3,5 diols were achieved
4) An expedious way making a Trienol
-Boron Chemistry
4) Boronolactonisation 4) Suzuki coupling of beta and gamma hydroxyl boronates with vinyl/aryl halides- JOC 2000 .455. Titanium chemistry – ZirconoceneChemsitry
5) Finished M.D Program at Windsor University, working as part-timeLecturer .Of anatomy and associate physician.
6) Titianocene induced Deoxygenating of diepoxy alcohols- A convenient regio selective preparation of 1,3 diols Yadav J.S and Dale Srinivas Chemistry lett 1997 , 905.
7) Taxol synthesis ; Synthesis of A ring and a methodology for substituted cyclohexadienes Yadav J.S and Dale Srinivas Tetrahedron lett 1997, 7789-7792.
8) Indium in Organic synthesis; Convenient preparation of BY unsaturated ketones YadavJ.S& Dale Srinivas, S.R reddy , HimabinduKonuru Tetrahedron lett 1997, 8745-8748.
9) A general synthesis of Isothiocyanates from Dithiocarbomates using clay copp
HMMeshram Dale Srinivas and J.S Yadav Tetrahedron lett 1997 8743-8744
New Method for Esterification of t alcohols which is not possible with conventional methods
10) Zinc promoted mild and efficient method for esterification of acid chlorides with t alcohols . Yadav J.S Dale Srinivas and GS Reddy Synthetic communications 1998 28(13) 2337-2342.
11) Microwave Thermolysis; A rapid and general method for the regeneration of clay carbonyls using clay supported Ammonium nitrate under microwave irradiation
HM Meshram DaleSrinivas, GS reddy, and Yadav J.S 1998 5706-5713.
New reagents Clayan
12) Clay supported Ammonium nitrate ‘ Clayan ‘ A mild and highly selective reagent for the De Oximation of electron rich Oximes. MeshramH.M DaleSrinivas and GS Reddy, Synthetic commun 1998 5706-5713
New Deprotection Method
13) Amild and versatile method for the Tetrahydropyranilation of alcohols and their De tetrhaydropyronyaltion. YadavJ.S Dale Srinivas and GSReddy Synthetic Communications1998 1199-1404.
14) Microwave induced Wittigolefination of lactones Sabitha MMReddy, Dale srinivas and Yadav JS Tetrahedron Lett 1999165-166.
15) Microwave Thermolyisis. A direct Conversion of Acid Chlorides to Acetalenic esters through Wittig reaction, Sabitha Dale Srinivas& Yadav JS Tetrahedronlett 1999.203.
16) A novel and efficient Deprotection of Benzilic ethers and methoxybenzyllic ethers by NBS Yadav JS Dale Srinivas and GSReddy synthetic commun 1999 254.
17) approaches for Taxol skeleton ; A study of Diels – Alder vs. Ene reaction Yadav JS Mania pp &Dale Srinivas&Chandrashekaran J chem. Comm. 1996 , 1997.
18) A Radical approach; Synthesis of A- B ring system of Taxol Yadav JS & Dale Srinivas (manuscript under preparation)
19) Tantalum induced unprecedented region-specific cyclisation of homo allylic epoxides to substituted furans and its appliacation to Spiro compounds Yadav JS & Dale Srinivas synthetic communications 2002 , 345 .
20) Anew and novel method for Butyl lithium titrations using 2,2 Bipyridyl as catalyst.
Dale Srinivas * analytical chemistry PJC 2000 , 456.
21) Indium mediated allylsulphone synthesis in water. Dale Srinivas* PJC 2002 , 7
22) Poster presented titled Synthetic studies towards the total synthesis of Taxol ‘At International conference on Organicsynthesis (ICOS10) India 185 Dec 1994
23) Poster presented titled Titanocene induced new synthetic methods at International conference on Organic synthesis (ICOS10) India p 185. Dec 1994.
24) Poster presented titled ‘ A straight forward synthesis of Bis pyro phosphates ‘ National symposium ‘ Dallas, TX. US 1998
25) Work presented at year wise biochemistry symposium Nov 1997, Vanbrawnhels , TX.US
26) Participated in HPLC, NMR and Mass presentations, in Boron chemistry Dept 1998 at UT South Western medical center, Dallas.
27) American Chemical Society Publications, Journal of Organic Chemistry
JRFalckMuralidhar, Sylesh , and Dale SrinivasJ.Org.Chem 2001 66(21) pp 7148-7150.
28 ) Titanium (III) mediated regiospecific reduction of vinyl epoxides. Yadav JS, Shekaram T and Srinivas Dale Tetrshedronlett 33 7973 1992.
28) PMHS reduction of Acyl Halides and aryl halides amildrosenmund reaction
Dale Srinivas presented at Chicago ACS symposium.
29) Taxol Synthesis ; Ato AB Ring syntheis through Acyloin Condensation
Dale Srinivas presented at Chicago ACS symposium
30 ) Presently involved in Medical research as well as Bioethanol /Rice bran oil , Nanotechnology research , pheromone synthesis , Organometalics , RNA research and asymmetric synthesis etc .
31) Claysin : A new reagent for Isothiocyanatepreparation.Bull. Socchem..In 30 .1774,2010.
32) Intramolecular Suzuki coupling : A new Strategy for Platencin synthesis Chemical soc. Kr Manuscript under preparation .
33) Clay SN a new reagent for oxidative transformations of organic chemistry (protection and deprotection chemistry)
34) Nanozyme induced oxydo reductase reactions(manuscript underpreparation)
35) Nanoboats : Anew theory for polar drugs to pass Barriers (Blood brain , Blood gas Blood placental and blood testis barriers )( AISM Press).
36) Nanotechnology: Nanoparticle+K+ channel blocker complex induced enhancement of Ach efficacy by allosteric modulations.Dale Srinivas* VijayaSrivastava, CheddieValmicky, BhanedattCarissa and Brij.BTewari 4th ICDDT “Hot Topics in natural products”saif zone , sharzah,UAE 2012 feb
37) ClaySN: A new reagent for the organic transformations , Dale Srinivas*,Vijaya Srivastava, Cheddievalmicky , Bhanedatt Carissa and Brij.B. Tewari 4th ICDDT “Hot Topics in natural products”saif zone , sharzah,UAE 2012 feb
38) A methodology for Innovative Suzuki coupling and its applications towards the Taxol synthesis , Dale Srinivas*4th ICDDT “Hot Topics in natural products”saif zone , sharzah,UAE 2012 feb
39) Anew Idea for Malarial research: Studies directed towards the invention of Hemozoin sensors for SMA Diagnosis Dale Srinivas*, Vijaya Srivastava Carissa bhanedatt and Brij.B.Tewari4th ICDDT “Hot Topics in natural products”saif zone , sharzah,UAE 2012 feb.
40)“Titanocene in organic synthesis: An expeditious approach to the synthesis of tetraenols” – Conference held atThe University of Jordan, Amman, Jordan, April 2012.
41) Nanotechnology : An attempt to explain
Central problem for Origin of Life studies by using Clay Nanoparticles and Enzymes (Nanozyme) Conference held at 39th COSPAR Scientic Assembly, Banglore , India; May, 2012..
42)Boronic acid in Organic Synthesis : Borono-lactonisation of Conjugated Dienes as A new 1,4 Addition products with NBS/HOH. 39th COSPAR Scienti_c Assembly entitled
43)Antibacterial Therapy: the enhanced antibacterial potency of the active compounds found in turmeric and neem in the presence of sunlight. 2012 Northwest Regional Meeting, June, 2012.
44) NORM1268 titled "Antifungal Therapy: An Innovative Treatment for Pathogenic Yeasts by Garlic Extract .Turmeric paste independently or combination with and without ketoconazole.June , 2012.
45)NORM1253 titled "ClayLS: A new colloidal reagent for the Tetrahydropyranilation. 2012 Northwest Regional Meeting, June, 2012.
46) Turmeric in Antimicrobial therapy: An interesting study on Gram-ve and Gram+ve organism. Colloids and Nanomedicine 2012 converence, Netherlands, July, 2012.
47) Boronic acid in Organic Synthesis:Boronolactonisation of Conjugated Dienes as A new 1,4 Addition products with NBS/HOH. Colloids and Nanomedicine 2012 converence, Netherlands, July, 2012.
48)Nanotechnology : Nanozyme induced Allosteric effects. Colloids and Nanomedicine 2012 converence, Netherlands, July, 2012
49)Boronic acid in Organic Synthesis : Borono-lactonisation of Conjugated Dienes as A new 1,4 Addition products with NBS/HOH. 39th COSPAR Scienti_c Assembly, Mysore, India.
50) Interaction of Aromatic Amines with Metal Ferrocyanides and its
Relevance to Chemical Evolution and Origins of Life. Scientific Online Platform (ConfTool)Origins 2011 International Conference
Montpellier, France, July 3rd-8th 2011.
References
Dr. J. S Yadav
Director of India Institute of Technology
Hyderabad, India.
Dr .H.M Meshram
Scientist F , I.I.C.T
Hyderabad , India
Dr Izaac Vicepesident
AISM , NEW YORK
Prof. Brij Tewari
University of Guyana
Georgetown Guyana
Dr. Y R Reddy
Scientist north Carolina
USA