Virtue PostMortem

Soy

Soy contains phytoestrogens, which are molecules similar to the oestrogen molecules. Its effect on human hormones is generally anti-estrogenic.

Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies - PubMed

Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review

The anti-estrogenic activity of phytoestrogens is due to their structural similarity with 17-β-estradiol (E2), the main female sex hormone. As well as interacting with ERs, phytoestrogens can affect the secretion of gonadotropin-releasing hormone (GnRH). Phytoestrogens could disrupt the endocrine system by interfering with the hypothalamic–pituitary–gonadal axis, which controls estrogen secretion. The hypothalamus releases GnRH and stimulates the pituitary to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH), gonadotropins that promote the secretion of estrogen, progesterone, and testosterone by the ovaries or testes. Low estrogen levels are a signal for the hypothalamus to release GnRH, whereas high levels provide a negative feedback. Therefore, the presence of exogenous compounds structurally similar to E2 may interfere with this system.

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